v3.26.1
Segment Information - Schedule of Operating Segments (Details) - USD ($)
$ in Thousands
 3 Months Ended
Mar. 31, 2026
Mar. 31, 2025
Operating expenses:    
External research and development costs [1] $ 60,819 $ 46,387
General and administrative operations 21,953 16,709
Depreciation expense 408 207
Interest income, net (8,740) (7,840)
Provision for income taxes 79 83
Consolidated net loss (74,111) (55,339)
Reportable Segment    
Operating expenses:    
Research and development personnel-related (excluding equity-based compensation) [2] 18,542 15,296
External-discovery related costs and other [2],[3] 8,433 5,437
General and administrative personnel-related (excluding equity-based compensation) [2] 7,985 5,707
General and administrative operations [2],[4] 5,009 5,105
Equity-based compensation [2] 17,155 11,126
Depreciation expense [2] 408 207
Interest income, net [2] (8,740) (7,840)
Provision for income taxes [2] 79 83
Consolidated net loss [2] 74,111 55,339
Reportable Segment | Zumilokibart (APG777)    
Operating expenses:    
External research and development costs [2] 19,542 14,571
Reportable Segment | APG990 / APG279    
Operating expenses:    
External research and development costs [2] 5,444 3,213
Reportable Segment | APG333 / APG273    
Operating expenses:    
External research and development costs [2] $ 254 $ 2,434
[1] Includes related party amounts of $640 and $32 for the three months ended March 31, 2026 and 2025, respectively.
[2] The significant expense categories and amounts align with the segment-level information that is regularly provided to the CODM.
[3] External-discovery related costs and other include expenses related to APG808.
[4] General and administrative operations are comprised of finance, investor relations, business development, human resources, legal, facilities & IT, and certain overhead expenses.