75000 - Document - Document and Entity Information
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75010 - Statement - Condensed Balance Sheets
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75020 - Statement - Condensed Balance Sheets (Parenthetical)
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75030 - Statement - Condensed Statements of Operations and Comprehensive Loss
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75040 - Statement - Condensed Statements of Stockholders Equity
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75050 - Statement - Condensed Statements of Stockholders Equity (Parenthetical)
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75060 - Statement - Condensed Statements of Cash Flows
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995455 - Disclosure - Description of Business and Basis of Presentation
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995465 - Disclosure - Summary of Significant Accounting Policies
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995475 - Disclosure - Fair Value Measurements
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995485 - Disclosure - Property and Equipment
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995495 - Disclosure - Long-term Investment
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995505 - Disclosure - Accrued Expenses and Other Current Liabilities
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995515 - Disclosure - Leases
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995525 - Disclosure - Capital Stock
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995535 - Disclosure - Stock-Based Compensation
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995545 - Disclosure - Net Loss Per Share
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995555 - Disclosure - Commitments and Contingencies
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995565 - Disclosure - License, Acquisition, Research and Collaboration and Sponsored Research Agreements
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995575 - Disclosure - Segment Information
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995585 - Disclosure - Subsequent Events
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995595 - Disclosure - Summary of Significant Accounting Policies (Policies)
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995605 - Disclosure - Fair Value Measurements (Tables)
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995615 - Disclosure - Leases (Tables)
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995625 - Disclosure - Property and Equipment (Tables)
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995635 - Disclosure - Accrued Expenses and Other Current Liabilities (Tables)
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995645 - Disclosure - Capital Stock (Tables)
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995655 - Disclosure - Stock-Based Compensation (Tables)
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995665 - Disclosure - Net Loss Per Share (Tables)
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995675 - Disclosure - Segment Information (Tables)
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995685 - Disclosure - Description of Business and Basis of Presentation - Additional Information (Details)
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995695 - Disclosure - Summary of Significant Accounting Policies - Additional Information (Details)
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995705 - Disclosure - Fair Value Measurements - Schedule of Fair Value Hierarchy for Assets and Liabilities Measured at Fair Value on Recurring Basis (Details)
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995715 - Disclosure - Fair Value Measurements - Schedule of Investments in U.S. Treasury Securities Classified as Available-for-Sale Securities (Details)
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995725 - Disclosure - Property and Equipment - Schedule of Property and Equipment, Net (Details)
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995735 - Disclosure - Long-term Investment - Additional Information (Details)
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995745 - Disclosure - Accrued Expenses and Other Current Liabilities - Summary of Accrued Expenses and Other Current Liabilities (Details)
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995755 - Disclosure - Leases - Additional Information (Details)
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995765 - Disclosure - Leases - Components of Operating Lease (Details)
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995775 - Disclosure - Leases - Reconciliation of Remaining Undiscounted Contractual Rent Obligations (Details)
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995785 - Disclosure - Leases - Reconciliation of Remaining Undiscounted Contractual Rent Obligations (Details) 2
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995795 - Disclosure - Leases - Components of Equipment Finance Leases (Details)
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995805 - Disclosure - Leases - Reconciliation of Remaining Equipment Finance Lease Obligations (Details)
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995815 - Disclosure - Leases - Reconciliation of Remaining Equipment Finance Lease Obligations (Details) 2
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995825 - Disclosure - Capital Stock - Additional Information (Details)
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995835 - Disclosure - Capital Stock - Schedule of Fair Value Assumptions of Warrants (Details)
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995845 - Disclosure - Capital Stock - Schedule of Common Stock Reserved for Future Issuances (Details)
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995855 - Disclosure - Stock-Based Compensation - Additional Information (Details)
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995865 - Disclosure - Stock-Based Compensation - Summary of Stock Option Activity (Details)
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995875 - Disclosure - Stock-Based Compensation - Summary of Estimated Fair Value of Stock Options Granted Using Black-Scholes Option Pricing Model with Following Assumptions (Details)
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995885 - Disclosure - Stock-based Compensation - Summary of RSU Activity and PRSU Activity (Details)
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995895 - Disclosure - Stock-Based Compensation - Summary of Stock-based Compensation Expenses (Details)
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995905 - Disclosure - Net Loss Per Share - Schedule of Net Loss Per Share Attributable to Common Stockholders (Details)
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995915 - Disclosure - Commitments and Contingencies - Additional Information (Details)
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995925 - Disclosure - License, Acquisition, Research and Collaboration and Sponsored Research Agreements - Additional Information (Details)
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995935 - Disclosure - Segment Information - Additional Information (Details)
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995945 - Disclosure - Segment Information - Summary of Additional Information On Company's Net loss Including Segment Expenses (Details)
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995955 - Disclosure - Subsequent Events - Additional Information (Details)
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Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Vested in Period, Weighted Average Grant Date Fair Value
Weighted average grant date fair value, vested
License and Acquisition and Research Collaboration and Sponsored Research Agreements Disclosure [Text Block]
License and acquisition and research collaboration and sponsored research agreements disclosure.
License, Acquisition, Research and Collaboration and Sponsored Research Agreements
All other research and development expense
Other Research and Development Expense
Internal Use Software
Software Development [Member]
Finance Lease, Liability
Total finance lease liabilities
Entity Incorporation, State or Country Code
Finance Lease, Liability, to be Paid, Year Four
2029
Increase (Decrease) in Accounts Payable, Total
Accounts payable
Increase (Decrease) in Accounts Payable
Supplemental disclosure of non-cash activities
Cash Flow, Noncash Investing and Financing Activities Disclosure [Abstract]
Plan Name [Axis]
Research and Development Expense [Abstract]
Research and development expense
Equity [Abstract]
Grantee Status [Domain]
Entity Current Reporting Status
Third Parties for Pharmaceutical Manufacturing and Research Activities
Third Parties For Pharmaceutical Manufacturing And Research Activities [Member]
Third parties for pharmaceutical manufacturing and research activities.
Proceeds from Warrant Exercises
Proceeds from exercise of common warrants
Operating expenses
Operating Expenses [Abstract]
Level 2 [Member]
Fair Value, Inputs, Level 2 [Member]
Commitments and Contingencies
Commitments and Contingencies Disclosure [Text Block]
Common stock, Authorized
Common stock shares authorized
Common Stock, Shares Authorized
Convertible preferred stock, par value
Temporary Equity, Par or Stated Value Per Share
Investment, Policy [Policy Text Block]
Long-term Investment
Document Fiscal Period Focus
May Two Thousand Twenty Five Private Placement [Member]
May two thousand twenty five private placement.
May 2025 Private Placement [Member]
Total lease payments
Finance Lease, Liability, to be Paid
Finance Lease, Liability [Abstract]
Included in the balance sheet:
Entity Shell Company
Convertible Preferred Stock Outstanding
Temporary equity, balance, shares
Temporary equity, balance, shares
Convertible preferred stock, shares outstanding
Temporary Equity, Shares Outstanding
Grantee Status [Axis]
Other current liabilities
Other Accrued Liabilities, Current
Dividends, Common Stock, Cash
Dividends, common stock, cash
Maximum Increase Or Decrease In Ownership Percentage
Maximum increase or decrease in ownership percentage.
Maximum increase or decrease in ownership percentage
Summary of Significant Accounting Policies [Line Items]
Summary of significant accounting policies.
Cash and cash equivalents at end of period
Cash and cash equivalents at beginning of period
Cash and cash equivalents, including restricted cash
Cash and cash equivalents
Cash and Cash Equivalent
Cash and Cash Equivalents, at Carrying Value, Total
Research and Development Arrangement, Contract to Perform for Others, Type [Axis]
Common Stock, Shares issued
Common Stock, Shares, Issued
Common stock, shares issued
Share based compensation payment description
Share Based Compensation Payment Description
Share based compensation payment description.
Statement Table
Statement [Table]
Office Facility and Laboratory Space
Office Facility and Laboratory Space [Member]
Office facility and laboratory space.
Restricted cash included in long-term assets at end of period
Restricted cash included in long-term assets at beginning of period
Restricted cash
Restricted Cash, Noncurrent
Weighted average grant date fair value, granted
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Grants in Period, Weighted Average Grant Date Fair Value
Weighted-average grant date fair value of stock options granted
Statement [Line Items]
Statement [Line Items]
Leerink Partners LLC [Member]
Leerink Partners LLC.
Business Combination [Domain]
Weighted average exercise price, Expired
Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Expirations in Period, Weighted Average Exercise Price
Warrant [Member]
Warrants
Entity Filer Category
Third UCSD License Agreement
Third UCSD License Agreement [Member]
Third UCSD License Agreement.
Liabilities and Equity
Total liabilities and stockholders' equity
October 2025 Financing Transactions [Member]
October 2025 Financing Transactions.
Long-term Investment
Long Term Investment Policy Text Block
Long term investment policy text block.
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Weighted Average Exercise Price
Weighted average exercise price, Options exercisable
Two thousand twenty one and two thousand twenty three equity incentive plan.
Two Thousand Twenty One And Two Thousand Twenty Three Equity Incentive Plan [Member]
2021 Plan and 2023 Plan
2021 Plan and 2023 Plan [Member]
Long-Lived Tangible Asset [Axis]
Finance Lease, Liability, to be Paid, Year Three
2029
Asset acquisition percentage of outstanding stock acquisition
Business Combination, Voting Equity Interest Acquired, Percentage
Development and commercialization milestones due
Development and Commercialization Milestones Due
Development and commercialization milestones due.
Cash and Cash Equivalents, Fair Value Disclosure
Cash equivalents (money market)
Offering price per share
Shares Issued, Price Per Share
Subsequent Event [Line Items]
Exercise of Outstanding Stock Options
Finance Lease, Liability, to be Paid, Remainder of Fiscal Year
2026
Investment Income, Interest
Interest income
Treasury Stock, Common, Value
Treasury stock, at cost, 3,827 common shares as of March 31, 2026 and as of December 31, 2025
Royalty payments description
Research and Development Arrangement, Contract to Perform for Others, Description and Terms
Second Amendment To The Third Cornell License Agreement
Second Amendment To The Third Cornell License Agreement [Member]
Second Amendment to the Third Cornell License Agreement [Member].
Debt Securities, Available-for-Sale, Noncurrent
Non-current portion of investments in U.S. Treasury securities
Common stock shares issued on early exercise of unvested stock options.
Common Stock Shares Issued On Early Exercise of Unvested Stock Options
Common stock shares issued upon early exercise of unvested stock options
Additional paid-in capital
Additional Paid in Capital, Common Stock
Series A Convertible Preferred Stock
Series A Convertible Preferred Stock [Member]
Series A convertible preferred stock.
Third-Party Commissions And Offering Costs Incurred Upon October 2025 Financing Transactionsmmissions and offering costs incurred upon October 2025 Financing Transactions
Third-party commissions and offering costs incurred upon October 2025 Financing Transactions
Third-party commissions and offering costs incurred upon October 2025 Financing Transactions
Equity Securities, FV-NI, Noncurrent
Long-term investment
Summary of Significant Accounting Policies
Significant Accounting Policies [Text Block]
Property, Plant and Equipment [Line Items]
Third Portfolio
Third Portfolio [Member]
Third portfolio.
Measurement Input, Risk Free Interest Rate [Member]
Risk-free Interest Rate [Member]
Vesting [Domain]
Granted, shares
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Grants in Period, Gross
Schedule of Net Loss Per Share Attributable to Common Stockholders
Schedule of Earnings Per Share, Basic and Diluted [Table Text Block]
Research and Development Expense LX2006
Research and Development Expense LX2006.
LX2006
Investment, Name [Axis]
Schedule of Aggregate Fair Values of Investments Classified as Available-for-Sale Securities With Unrealized Losses and Gains
Investments Classified by Contractual Maturity Date [Table Text Block]
Earnings Per Share, Basic
Earnings Per Share, Basic, Total
Net loss per common share, basic
Net loss per share attributable to common stockholders, basic
Common Stock During Offering Period
Common Stock During Offering Period
Common stock during offering period
Number of shares outstanding, ending
Number of shares outstanding, beginning
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Number
Schedule of Available-for-Sale Securities Reconciliation [Table Text Block]
Schedule of Investments in U.S. Treasury Securities Classified as Available-for-Sale Securities
Number of former employees.
Number of Former Employees
Number of former employees
Total current liabilities
Liabilities, Current
Adjustment to Reconcile Net Income to Cash Provided by (Used in) Operating Activity [Abstract]
Adjustments to reconcile net loss to net cash used in operating activities:
Operating lease end date
Operating Lease End Date
Operating lease end date.
Consolidation Items [Domain]
Consolidation Items [Domain]
Equity, Attributable to Parent [Abstract]
Stockholders' equity:
Entity Small Business
Unpaid Offering Costs Included In Accounts Payable And Accrued Expenses
Unpaid Offering Costs Included In Accounts Payable And Accrued Expenses
Unpaid offering costs included in accounts payable and accrued expenses
Accumulated deficit
Retained Earnings (Accumulated Deficit)
Retained Earnings (Accumulated Deficit), Total
Forfeited, shares
Forfeited, shares
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Forfeitures in Period
Investee
Investment in Equity Securities of Investee [Member]
Investment in equity securities of investee.
Imputed interest rate
Lessee, Finance Lease, Discount Rate
Volume-weighted average price per share
Sale of Stock, Price Per Share
General and Administrative Expense Employee Compensation Expenses
General and administrative expense employee compensation expenses.
Employee compensation expenses
Aggregate intrinsic value, exercised
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercises in Period, Intrinsic Value
Intrinsic value of stock options exercised
Warrants and Rights Outstanding, Measurement Input
Measurement input
Stock-Based Compensation
Share-Based Payment Arrangement [Text Block]
Organization, Consolidation and Presentation of Financial Statements [Abstract]
Leases [Abstract]
Lessee, Lease, Description [Line Items]
Amendment
Amendment Flag
Loss Contingencies [Line Items]
Proceeds from Sale, Maturity and Collection of Investments
Proceeds from Sale, Maturity and Collection of Investments, Total
Proceeds from sales or maturities of investments
Class of Warrant or Right, Number of Securities Called by Warrants or Rights
Warrants to purchase shares of common stock
Interest on finance lease liabilities
Finance Lease, Interest Expense
Net Loss per Share
Earnings Per Share, Policy [Policy Text Block]
Liabilities and Equity [Abstract]
Liabilities and Stockholders' equity
Entity Address, Postal Zip Code
Leerink At The Market Sales Agreement [Member]
Leerink at the market sales agreement.
Leerink At The Market Sales Agreement [Member]
Fair Value Of Warrants Per Share
Fair value of warrants per share.
Fair value of warrants per share
Net cash used in operating activities
Cash flow from operations
Cash Provided by (Used in) Operating Activity, Including Discontinued Operation
Termination notice period (in days)
License agreement termination notice period
License Agreement Termination Notice Period
License agreement termination notice period.
Increase (Decrease) in Operating Lease Liability
Lease liabilities, operating
Common Stock [Member]
Common Stock [Member]
October 2025 Private Placement
October 2025 Private Placement [Member]
October 2025 Private Placement.
Weighted average exercise price, granted
Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Grants in Period, Weighted Average Exercise Price
Lessee, Operating Lease, Liability, to be Paid, Year Three
2029
Less: accumulated depreciation and amortization
Accumulated Depreciation, Depletion and Amortization, Property, Plant, and Equipment
Accumulated Depreciation, Depletion and Amortization, Property, Plant, and Equipment, Ending Balance
Accumulated Depreciation, Depletion and Amortization, Property, Plant, and Equipment, Beginning Balance
Accumulated Depreciation, Depletion and Amortization, Property, Plant, and Equipment, Total
Less: accumulated depreciation
Debt Securities, Available-for-Sale [Line Items]
Research and Development Arrangement, Contract to Perform for Others, Type [Domain]
Entity Address, Address Line One
Schedule of Share-Based Payment Award, Stock Options, Valuation Assumptions [Table Text Block]
Summary of Estimated Fair Value of Stock Options Granted Using Black-Scholes Option Pricing Model with Following Assumptions
Fair Value Hierarchy and NAV [Axis]
Payroll Deductions at Price
Payroll Deductions at Price
Payroll deductions at price
Earnings Per Share [Abstract]
Abiomed Agreement [Member]
Abiomed Agreement [Member].
Total gross
Finance Lease, Right-of-Use Asset, before Accumulated Amortization
Operating lease right-of-use assets
Lease right-of-use assets - operating
Operating Lease, Right-of-Use Asset
Less: imputed interest
Less: imputed interest
Finance Lease, Liability, Undiscounted Excess Amount
Fair value of unearned employee stock ownership plans
Fair Value of Unearned Employee Stock Ownership Plans
Fair Value of Unearned Employee Stock Ownership Plans
Changes in operating assets and liabilities:
Increase (Decrease) in Other Operating Assets and Liabilities, Net [Abstract]
Class of Warrant or Right [Axis]
Document Type
Document Type
Collaborative Arrangement and Arrangement Other than Collaborative [Axis]
Number of monthly installments
Number Of Monthly Installments Lease
Number of monthly installments lease.
Collaborative Arrangement and Arrangement Other than Collaborative [Domain]
CIK
Entity Central Index Key
October 2025 Public Offering [Member]
October 2025 Public Offering.
October 2025 Public Offering
Net change in cash, cash equivalents and restricted cash
Cash, Cash Equivalent, Restricted Cash, and Restricted Cash Equivalent, Period Increase (Decrease), Including Exchange Rate Effect and Discontinued Operation
Subsequent Event Type [Domain]
Two Portfolios
Two Portfolios [Member]
Two portfolios.
Antidilutive securities excluded from Computation of diluted net loss per common share
Antidilutive Securities Excluded from Computation of Earnings Per Share, Amount
Leases
Lessee Operating And Financing Leases Disclosure [Text Block]
Lessee Operating And Financing Leases Disclosure.
Common stock, par value per share
Common Stock, Par or Stated Value Per Share
Security deposit
Security Deposit
One-time up-front non-refundable fees
One Time Up Front Non Refundable Fees
One time up front non refundable fees.
Share-Based Payment Arrangement, Tranche One [Member]
Vest Over 4 Month to 11 Month [Member]
Operating Lease, Right-of-Use Asset, Periodic Reduction
Reduction in the carrying amount of ROU assets, operating
Weighted average remaining contractual term
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Remaining Contractual Term
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Volatility Rate, Maximum
Expected volatility, range, maximum
Fair Value Of Shares Received
Fair value of shares received.
Fair value of shares received
Debt Securities, Available-for-Sale, Amortized Cost
Amortized Cost Basis
Amortized Cost Basis
Workers' Compensation Liability, Current
Accrued compensation and other personnel costs
Fair Value
Debt Securities, Available-for-Sale
Available-for-sale securities
Schedule of Common Stock Reserved for Future Issuances
Schedule of Stockholders Equity [Table Text Block]
Treasury stock repurchase
Treasury stock repurchase
Treasury Stock Repurchase
Treasury stock repurchase.
Series B Convertible Preferred Stock
Series B Convertible Preferred Stock [Member]
Series B convertible preferred stock.
Exercised, shares
Exercise of stock options, shares
Exercised, shares
Stock options exercised
Development and regulatory milestones due
Development and Regulatory Milestones Due
Development and regulatory milestones due.
Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Line Items]
Current Fiscal Year End Date
Document Quarterly Report
Entity Address, State or Province
Investment Income, Net, Amortization of Discount and Premium
Investment Income, Net, Amortization of Discount and Premium, Total
(Amortization of premium) accretion of discount on investments in U.S. Treasury securities, net
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Number
Number of shares unvested, ending balance
Number of shares unvested, beginning balance
Long Term Investment [Text Block]
Long term investment.
Long-term Investment
Investment, Name [Domain]
Comprehensive loss
Comprehensive Income (Loss), Net of Tax, Attributable to Parent
Comprehensive loss
Gross Unrealized Gains
Debt Securities, Available-for-Sale, Accumulated Gross Unrealized Gain, before Tax
2023 Plan
Two Thousand Twenty Three Equity Incentive Plan [Member]
Two Thousand Twenty Three Equity Incentive Plan.
Total shares of common stock reserved for future issuance
Common stock, shares reserved for issuance
Common Stock, Capital Shares Reserved for Future Issuance
All Other Officers [Member]
All Other Officers.
All Other Officers
Second cornell license agreements.
Second Cornell License Agreements [Member]
Second Cornell License Agreements
Class of Warrant or Right [Domain]
Thereafter
Finance Lease Liability Payments Due After Year Four
Finance lease liability payments due after year four.
Other General and Administrative Expense
All other general and administrative expense
Two thousand and twenty three equity incentive plan.
Two Thousand and Twenty Three Equity Incentive Plan [Member]
2023 Plan
2023 Plan [Member]
Exercise of stock options, value
Stock Issued During Period, Value, Stock Options Exercised
Accrued Expenses and Other Current Liabilities
Accounts Payable, Accrued Liabilities, and Other Liabilities Disclosure, Current [Text Block]
Subsequent Event
Subsequent Event [Member]
Contractual term grant date
Share Based Compensation Arrangement by Share Based Payment Award Contractual Term Grant Date
Share Based Compensation Arrangement by Share Based Payment Award Contractual Term Grant Date
Property, Plant and Equipment [Abstract]
Current portion of investments in U.S. Treasury securities
Debt Securities, Available-for-Sale, Current
Antidilutive Securities [Axis]
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Expirations in Period
Expired, shares
Expired, shares
Vesting period, percentage
Share-Based Compensation Arrangement by Share-Based Payment Award, Award Vesting Rights, Percentage
Payment of regulatory milestones
Payment of Regulatory Milestones
Regulatory milestone to be paid
Summary of Stock-Based Compensation Expenses
Share-Based Payment Arrangement, Cost by Plan [Table Text Block]
AOCI Attributable to Parent [Member]
Accumulated Other Comprehensive Income (Loss) [Member]
Treasury stock, common shares
Treasury Stock, Common, Shares
Cash and Cash Equivalents [Domain]
Option to extend
Lessee, Operating Lease, Option to Extend
Amended UCSD Sponsored Research Agreement [Member]
Amended UCSD Sponsored Research Agreement [Member].
Minimum
Minimum
Minimum [Member]
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Grants in Period, Weighted Average Grant Date Fair Value
Weighted average grant date fair value, granted
Financial Instrument [Axis]
Current assets:
Assets, Current [Abstract]
Non-Cash Gain on Long-term Investment
Non-cash gain on long-term investment
Non-cash gain on long-term investment
Non-cash gain (loss) on long-term investment.
Nonredeemable Convertible Preferred Stock [Member]
Nonredeemable Convertible Preferred Stock
Level 3 [Member]
Fair Value, Inputs, Level 3 [Member]
Notes issued
Notes Issued
Monthly installment payment amounts
Finance Lease Monthly Installment Payment Amounts
Finance lease monthly installment payment amounts
Segment Reporting [Abstract]
Segment Information [Abstract]
Segment Information [Abstract]
Net unrealized gain (loss) on investments
Unrealized gain (loss) on investments
Unrealized gain (loss) on investments
Unrealized comprehensive gain (loss) on investments in U.S. Treasury securities
Schedule of Fair Value Hierarchy for Assets and Liabilities Measured at Fair Value on Recurring Basis
Fair Value, Assets Measured on Recurring Basis [Table Text Block]
Current liabilities:
Liabilities, Current [Abstract]
Loss Recognized from Uninsured Balances
Loss recognized from uninsured balances
Loss recognized from uninsured balances.
Payment of annual license maintenance fees
Payment of Annual License Maintenance Fees
Annual license maintenance fees
Balance, shares
Balance, shares
Shares, Outstanding
Renewal term
Lessee, Operating Lease, Renewal Term
Number of Shares Automatically Increase in Available Shares of Common Stock Under Plan
Number of shares automatically increase in available shares of common stock under plan
Number of Shares Automatically Increase in Available Shares of Common Stock Under Plan
2021 Plan
Two Thousand Twenty One Equity Incentive Plan [Member]
Two thousand twenty one equity incentive plan member.
2021 Plan [Member]
Total proceeds
Proceeds from Stock Plans
Increase decrease in finance lease liability.
Lease liabilities, finance
Increase Decrease In Finance Lease Liability
Commitments and Contingencies
Commitments and contingencies (Note 11)
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Weighted Average Grant Date Fair Value
Weighted-average grant date fair value, unvested, ending balance
Weighted-average grant date fair value, unvested, beginning balance
General and administrative expense
General and Administrative Expense [Member]
Total operating lease liabilities
Operating lease liabilities
Current portion of lease liabilities - operating
Operating Lease, Liability
Scenario Forecast
Forecast [Member]
Stelios Therapeutics Inc
Stelios Therapeutics Inc [Member]
Stelios Therapeutics Inc.
Current portion of lease liabilities - finance
Finance Lease, Liability, Current
Lessee, Lease, Description [Table]
Weighted average effective interest rate
Weighted Average Effective Interest Rate
Finance Lease, Weighted Average Discount Rate, Percent
Non-current liabilities
Liabilities, Noncurrent [Abstract]
Accumulated amortization
Finance Lease, Right-of-Use Asset, Accumulated Amortization
Net loss
Net Income (Loss), Including Portion Attributable to Noncontrolling Interest
Net Income (Loss), Including Portion Attributable to Noncontrolling Interest, Total
Share-Based Payment Arrangement, Recognized Amount [Abstract]
Loss Contingencies [Table]
Weighted-average common shares outstanding, basic
Weighted Average Number of Shares Outstanding, Basic
Weighted Average Number of Shares Outstanding, Basic, Total
Weighted-average number of shares outstanding used in computation of net loss per common share, basic
Scenario [Axis]
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Intrinsic Value
Aggregate intrinsic value, Options exercisable
Segment Reporting, Expense Information Used by CODM, Description
Segment Reporting, Expense Information Used by CODM, Description
Schedule of Share-Based Compensation Arrangements by Share-Based Payment Award [Table]
Long-Lived Tangible Asset [Domain]
Two Thousand Twenty Three Employee Stock Purchase Plan [Member]
2023 Employee Stock Purchase Plan.
2023 ESPP
2023 ESPP [Member]
Proceeds from Issuance of Private Placement
Gross proceeds from private placement
Proceeds from issuance of common stock upon March 2024 Private Placement Offering
Weill Cornell Medical College
Weill Cornell Medical College [Member]
Weill Cornell medical college.
Subsequent Events
Subsequent Events [Text Block]
Research Agreements Term
Research agreements term.
Research agreements term
Clinical and regulatory milestone paid
Payment Of Clinical And Regulatory Milestone
Payment Of Clinical And Regulatory Milestone.
Balance, value
Balance, value
Equity, Attributable to Parent
Total stockholders' equity
Purchases of investments
Payments to Acquire Investments
Payments to Acquire Investments, Total
Purchases of investments
Preferred stock, par value per share
Preferred stock at par value
Preferred Stock, Par or Stated Value Per Share
Existence of option to extend
Lessee, Operating Lease, Existence of Option to Extend [true false]
Statement of Stockholders' Equity [Abstract]
Remaining lease payment terms
Operating Lease Weighted Average Remaining Payment Term
Operating lease weighted average remaining payment term.
Vest Over Two Year
Share-Based Payment Arrangement, Tranche Two [Member]
Use of Estimates
Use of Estimates, Policy [Policy Text Block]
Equity Method Investment [Table]
Treasury Stock, Common [Member]
Treasury Stock [Member]
Leasehold Improvements
Leasehold Improvements [Member]
Entity Address, Address Line Two
Fair Value Measurements
Fair Value Disclosures [Text Block]
Reconciliation of Remaining Equipment Finance Lease Obligations
Finance Lease, Liability, to be Paid, Maturity [Table Text Block]
Two Thousand Twenty Five Inducement Equity Plan [Member]
Two thousand twenty five inducement equity plan.
2025 Inducement Equity Plan [Member]
2025 Inducement Equity Plan
Debt Instrument, Name [Domain]
Fair Value Of Shares Received Per Share
Fair value of shares received per share.
Fair value of shares received per share
Accrued research and development expenses
Accrued Research And Development Expense Current
Accrued research and development expense current.
Asset acquisition date of acquisition
Business Combination, Effective Date of Acquisition
Share-Based Compensation Arrangement by Share-Based Payment Award, Per Share Weighted Average Price of Shares Purchased
Purchase price
Weighted average purchase price
Thirty-day Underwriter Option [Member]
30-day Underwriter Option [Member]
30-day Underwriter Option
Segment Reporting, CODM, Individual Title and Position or Group Name [Extensible Enumeration]
Segment Reporting, CODM, Individual Title and Position or Group Name [Extensible Enumeration]
UCSD Sponsored Research Agreements
UCSD Sponsored Research Agreements [Member]
UCSD sponsored research agreements.
Plan Name [Domain]
Accrued General And Administrative Expenses And Other Professional Fees Current
Accrued general and administrative expenses and other professional fees
Accrued general and administrative expenses and other professional fees current.
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Credit Facility [Axis]
Equity Method Investment, Ownership Percentage
Ownership percentage
Finance Lease, Liability, to be Paid, Year One
2027
Fair Value Of Warrants
Fair value of warrants.
Fair value of warrants
Total finance lease expense
Finance Lease Expense
Finance lease expense.
Entity Address, City or Town
Treasury stock repurchase, Shares
Repurchase of shares
Stock Repurchased During Period, Shares
Number of Reportable Segments
Number of reportable segment
Security Exchange Name
Issuance costs related to convertible debt included in accounts payable and accrued expenses
Debt Issuance Costs Incurred During Noncash or Partial Noncash Transaction
Credit Facility [Domain]
Total property and equipment
Property, Plant and Equipment, Gross
Property, Plant and Equipment, Gross, Ending Balance
Property, Plant and Equipment, Gross, Beginning Balance
Property, Plant and Equipment, Gross, Total
Adjustments To Additional Paid In Capital Reclassification From Deposit Liability Share Based Compensation And Exercise Of Stock Options, Share
Adjustments to additional paid in capital reclassification from deposit liability share based compensation and exercise of stock options, share.
Amounts reclassified from deposit liabilities upon the vesting of early-exercised stock options previously subject to repurchase, Shares
Counterparty Name [Axis]
Loss from operations before income taxes
Income (Loss) from Continuing Operations before Income Taxes, Noncontrolling Interest
First cornell license agreements.
First Cornell License Agreements [Member]
First Cornell License Agreements
Measurement Input Type [Domain]
Antidilutive Securities, Name [Domain]
Cash, Cash Equivalents, Restricted Cash, and Restricted Cash Equivalents, Total
Cash, Cash Equivalent, Restricted Cash, and Restricted Cash Equivalent, Continuing Operation
Cash, cash equivalents and restricted cash at beginning of period
Cash, cash equivalents and restricted cash at end of period
Number of license agreements
Number of License Agreements
Number of license agreements.
Share-Based Payment Arrangement, Nonemployee [Member]
Non-employee [Member]
Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Table]
Statistical Measurement [Domain]
Excercise price of warrant
Class of Warrant or Right, Exercise Price of Warrants or Rights
Exercise Price
Total current assets
Assets, Current
Total stock-based compensation expense
Share-Based Payment Arrangement, Expense
Increase in aggregate number of shares of common stock reserved for issuance
Increase In Common Stock Capital Shares Reserved For Future Issuance
Increase in common stock capital shares reserved for future issuance.
Period End Date
Document Period End Date
Equity Method Investments and Joint Ventures [Abstract]
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Weighted Average Volatility Rate
Expected volatility, weighted-average
Fair Value Hierarchy and NAV [Domain]
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Number
Number of shares, Options exercisable
Other Third Party [Member]
Other third-party.
Other Third-party [Member]
Employee compensation expenses
Research and Development Expense Employee Compensation Expenses
Research and development expense employee compensation expenses.
Summary of Significant Accounting Policies [Table]
Summary of significant accounting policies.
Statement of Financial Position
Statement of Financial Position [Abstract]
Restricted Stock Units (RSUs) [Member]
Restricted Stock Units [Member]
Vesting [Axis]
Class of Stock [Axis]
Restricted Stock Units and Performance Based Restricted Stock Units [Member]
Restricted stock units and performance based restricted stock units.
RSUs and PRSUs [Member]
Total liabilities
Liabilities
Equity-Based Arrangements, Individual Contracts, Type of Deferred Compensation [Domain]
Incremental borrowing rate
Lessee, Operating Lease, Discount Rate
Financial Instruments [Domain]
Finance lease right-of use assets and finance lease liabilities recognized
Finance Lease Right-of Use Assets And Finance Lease Liabilities Recognized
Finance lease right-of use assets and finance lease liabilities recognized.
Measurement Input, Exercise Price [Member]
Exercise Price [Member]
Authorized capital stock
Capital Units, Authorized
LX1001
Research and Development Expense LX1001
Research and development expense LX1001.
Third cornell license agreements
Third Cornell License Agreements [Member]
Third Cornell License Agreements
Research agreement termination notice period
Research Agreement Termination Notice Period
Research agreement termination notice period.
Lessee, Operating Lease, Liability, to be Paid, Year Two
2028
Specific clinical and regulatory milestones due.
Specific clinical and regulatory milestones due
Specific Clinical and Regulatory Milestones Due
Amortization of right-of-use assets, finance
Finance Lease, Right-of-Use Asset, Amortization
Reduction in the carrying amount of ROU assets, finance
Weighted-average common shares outstanding, diluted
Weighted Average Number of Shares Outstanding, Diluted
Weighted Average Number of Shares Outstanding, Diluted, Total
Weighted-average number of shares outstanding used in computation of net loss per common share,diluted
Entity File Number
Upfront payment in cash
Upfront Cash Payment
Upfront cash payment.
Cover
Cover [Abstract]
Expected volatility, range, minimum
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Volatility Rate, Minimum
Measurement Input Type [Axis]
Development and commercialization milestones description
Aggregate Development And Commercialization Milestones Description
aggregate development and commercialization milestones description.
Prepaid Expense and Other Assets, Current
Prepaid expenses and other current assets
Number of shares, forfeited
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Forfeited in Period
Number of shares, forfeited
Potential Future Product Sales Milestones
Potential future product sales milestones.
Potential future product sales milestones
Scenario [Domain]
US Treasury Securities [Member]
U.S. Treasury Securities [Member]
Number of operating segment
Number of Operating Segments
Sale of Stock [Domain]
Segment Reporting Disclosure [Text Block]
Segment Information
General and administrative
General and Administrative Expense
General and Administrative Expense, Total
Liquidation Preference
Convertible preferred stock, Liquidation Preference
Temporary Equity, Liquidation Preference
March Two Thousand Twenty Four Private Placement [Member]
March two thousand twenty four private placement.
March 2024 Private Placement [Member]
Subsequent Event [Table]
Payment To Additional Data Transfer Process
Payment to additional data transfer process.
Payment to additional data transfer process
Total operating lease expense
Operating Lease, Expense
Capital Expenditures
Capital Expenditures
(Property and equipment purchased in the prior period and paid in the current period), net of property and equipment purchased in the current period included in accounts payable
Useful Life
Estimated useful life
Property, Plant and Equipment, Useful Life
Reconciliation of Remaining Undiscounted Contractual Rent Obligations
Lessee, Operating Lease, Liability, to be Paid, Maturity [Table Text Block]
Share-Based Payment Arrangement, Restricted Stock and Restricted Stock Unit, Activity [Table Text Block]
Summary of RSU Activity and PRSU Activity
Percentage of automatically increase in available shares of common stock on beginning of each calendar year
Percentage of Automatically Increase in Available Shares of Common Stock on Beginning of Cach Calendar Year
Percentage of automatically increase in available shares of common stock on beginning of each calendar year.
Vesting period
Share-Based Compensation Arrangement by Share-Based Payment Award, Award Vesting Period
Third-party commissions and offering costs incurred upon Private Placement Offering
Payment of Financing and Stock Issuance Costs
Payment of Financing and Stock Issuance Costs, Total
One-time up-front non-refundable fee paid
Payment of One Time Up Front Non Refundable Fee
Payment of one time up front non refundable fee.
Risk-free interest rates, minimum
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Risk Free Interest Rate, Minimum
Costs incurred for research
Research and Development Arrangement, Contract to Perform for Others, Costs Incurred, Gross
Potential future product development milestones
Potential Future Product Development Milestones
Potential future product development milestones.
Amounts Reclassified From Deposit Liabilities Upon The Vesting Of Early-exercised Stock Options Previously Subject To Repurchase, Net Of Proceeds Received From Early Exercise Of Unvested Stock Options Subject To Repurchase And Recorded As Deposit Liabilities
Amounts reclassified from deposit liabilities upon the vesting of early-exercised stock options previously subject to repurchase, net of proceeds received from early exercise of unvested stock options subject to repurchase and recorded as deposit liabilities.
Amounts reclassified from deposit liabilities upon the vesting of early-exercised stock options previously subject to repurchase
Common stock, Outstanding
Common Stock, Shares, Outstanding
Common Stock, Shares, Outstanding, Ending Balance
Common Stock, Shares, Outstanding, Beginning Balance
Current portion of lease liabilities - operating
Operating Lease, Liability, Current
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Document Transition Report
Total operating expenses
Operating Expenses
Research and Development Expense
Research and development
Research and development
Research and development expenses
Statement of Cash Flows [Abstract]
Stock Issued During Period, Value, New Issues
Issuance of common stock, Value
Summary of Stock Option Activity
Share-Based Payment Arrangement, Option, Activity [Table Text Block]
Equity [Text Block]
Capital Stock
Proceeds from Issuance of Common Stock, Pre-funded Warrants and Warrants to Purchase Common Stock
Proceeds from issuance of common stock, pre-funded warrants and warrants to purchase common stock.
Proceeds from issuance of common stock, pre-funded warrants and warrants to purchase common stock upon May 2025 Private Placement Offering
Net Loss Per Share
Earnings Per Share [Text Block]
Measurement Input, Expected Dividend Rate [Member]
Expected Dividend Yield [Member]
Purchase of internal use software
Payments to Acquire Software
Net Loss
Net loss
Net Loss
Net loss
Performance Restricted Stock Unit [Member]
Performance Restricted Stock Unit.
Aggregate intrinsic value, ending
Aggregate intrinsic value, beginning
Aggregate intrinsic value, beginning
Aggregate intrinsic value, ending
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Intrinsic Value
Operating lease expense
Operating Lease, Cost
Warrants and Rights Outstanding, Term
Expected term (in years)
Common Stock Issuable Upon Conversion
Preferred Stock, Convertible, Shares Issuable
Converted shares into common stock
Expected dividend yield
Expected dividend yields percentage
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Dividend Rate
Adverum License Agreement
Adverum License Agreement [Member]
Adverum license agreement.
Cash paid for amounts included in the measurement of lease liabilities, included in operating cash flows
Operating Lease, Payments
Assets
Assets [Abstract]
Cornell University
Cornell University [Member]
Cornell university.
Risk-free interest rate
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Risk Free Interest Rate
Prepaid expenses and other current assets
Increase (Decrease) in Prepaid Expense and Other Assets
Document Fiscal Year Focus
Accrued expenses and other current liabilities
Total accrued expenses and other current liabilities
Accrued Liabilities And Other Liabilities Current
Accrued liabilities and other liabilities current.
Number of common shares on conversion of debt instrument
Shares issued on debt exchanged
Debt Conversion, Converted Instrument, Shares Issued
Equity-Based Arrangements, Individual Contracts, Type of Deferred Compensation [Axis]
Cash flows from investing activities:
Cash Provided by (Used in) Investing Activity, Including Discontinued Operation [Abstract]
Accounts payable
Accounts Payable, Current
Accounts Payable, Current, Total
Total grant date fair values of options vested
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested in Period, Fair Value
Interest Expense, Nonoperating, Total
Interest Expense, Nonoperating
Interest expense
Pre Funded Warrants [Member]
Pre-funded warrants.
Pre-funded Warrants
Research and Development Expense
Research and development expense
Research and Development Expense [Member]
Stock-based compensation expense
Shares Issued, Value, Share-Based Payment Arrangement, after Forfeiture
Shares Issued, Value, Share-Based Payment Arrangement, after Forfeiture, Total
Stock Offering Value Shares Authorized To Be Sold
Stock offering value shares authorized to be sold.
Common stock aggregate offering price
Net Proceeds from Issuance of Common Stock
Net proceeds from issuance of common stock.
Net proceeds received
Proceeds from exercise of stock options
Proceeds from Stock Options Exercised
Fair Value Disclosures [Abstract]
Deferred offering costs included in accounts payable and accrued expenses
Deferred Offering Costs Included In Accounts Payable And Accrued Expenses
Unpaid offering costs included in accounts payable and accrued expenses
Commitments and Contingencies Disclosure [Abstract]
Measurement Input, Share Price [Member]
Stock Price [Member]
Lessee, Operating Lease, Liability, to be Paid, Year One
2027
Sale of Stock, Consideration Received on Transaction
Net proceeds
Finance Lease Liability Payments Due After Year Three
Finance lease liability payments due after year three.
Thereafter
Offering costs included in accounts payable and accrued expenses.
Offering Costs Included In Accounts Payable And Accrued Expenses
Offering costs included in accounts payable and accrued expenses
Debt Instrument [Axis]
Share-Based Payment Arrangement [Abstract]
Unrecognized stock-based compensation expense
Share-Based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Amount
Share-Based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Amount, Total
Debt Securities, Available-for-Sale [Abstract]
Available-for-sale securities:
Total assets
Assets, Fair Value Disclosure
Assets, Fair Value Disclosure, Total
Sale of Stock [Axis]
Cash Provided by (Used in) Investing Activity, Including Discontinued Operation
Net cash provided by investing activities
Private Placement [Member]
Private Placement Offering
Private Placement Offering [Member]
Development milestone paid
Payment of Development Milestone
Payment of development milestone.
Weighted average remaining lease payment term
Weighted Average Remaining Lease Payment Term (in years)
Finance Lease, Weighted Average Remaining Lease Term
Title of 12(b) Security
Schedule of Segment Reporting Information, by Segment [Table]
Schedule of Segment Reporting Information, by Segment [Table]
Weighted average exercise price, forfeited
Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Forfeitures in Period, Weighted Average Exercise Price
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Forfeitures, Weighted Average Grant Date Fair Value
Weighted average grant date fair value, forfeited
Money Market Funds [Member]
Collaborative Arrangement and Arrangement Other than Collaborative [Table]
Convertible Preferred Stock Issued
Convertible preferred stock, shares issued
Temporary Equity, Shares Issued
Research and development Aarrangement, ontract to perform for others, dditional costs incurred.
Research and Development Arrangement, Contract to Perform for Others, Additional Costs Incurred
Additional costs incurred for research
Lessee, Operating Lease, Liability, to be Paid, Remainder of Fiscal Year
2026
Net book values
Finance Lease, Right-of-Use Asset, after Accumulated Amortization
Finance Lease, Right-of-Use Asset, after Accumulated Amortization, Total
Lease right-of-use assets - finance
Schedule of Property and Equipment, Net
Property, Plant and Equipment [Table Text Block]
Weighted average exercise price, beginning balance
Weighted average exercise price, ending balance
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Exercise Price
Fair Value, Recurring and Nonrecurring [Table]
Accrued Liabilities and Other Liabilities [Abstract]
Additional Paid-in Capital [Member]
Additional Paid-in Capital [Member]
Accrued expenses and other current liabilities
Increase (Decrease) in Accrued Liabilities and Other Operating Liabilities
Measurement Frequency [Domain]
Statement of Income Location, Balance [Axis]
Trading Symbol
Property and Equipment
Property, Plant and Equipment Disclosure [Text Block]
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Risk Free Interest Rate, Maximum
Risk-free interest rates, maximum
Second UCSD License Agreement
Second UCSD License Agreement [Member]
Second UCSD license agreement.
Subsequent Event Type [Axis]
Commissions and offering costs.
Commissions and Offering Costs [Member]
Commissions and Offering Costs
Operating Lease, Liability [Abstract]
Included in the balance sheet:
Cash flows from financing activities:
Cash Provided by (Used in) Financing Activity, Including Discontinued Operation [Abstract]
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Term
Expected term (in years), weighted-average
Fair Value Recurring [Member]
Fair Value, Recurring [Member]
Entity Ex Transition Period
Schedule of Equity Method Investments [Line Items]
Total lease payments
Lessee, Operating Lease, Liability, to be Paid
Less: present value adjustment
Lessee, Operating Lease, Liability, Undiscounted Excess Amount
Equity Components [Axis]
Total other income and expense
Nonoperating Income (Expense)
Other income and expense, net
Other income
Equity Component [Domain]
Amended First UCSD Agreement.
Amended First UCSD Agreement [Member]
Amended First UCSD Agreement
Business Combination [Axis]
Number of research agreements.
Number of research agreements
Number of Research Agreements
Payment of Annual Data Transfer Fee
Annual data transfer fee
Payment of annual data transfer fee.
Issuance of Common Stock Upon Vesting and Settlement of Restricted Stock Units
Issuance of common stock upon vesting and settlement of restricted stock units
Issuance of common stock upon vesting and settlement of restricted stock units, shares
Issuance of common stock upon vesting and settlement of restricted stock units, shares
Depreciation and amortization expense
Depreciation, Depletion and Amortization, Nonproduction
Depreciation, Depletion and Amortization, Nonproduction, Total
Maximum
Maximum
Maximum [Member]
Statistical Measurement [Axis]
Weighted average exercise price, exercised
Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Exercises in Period, Weighted Average Exercise Price
Common stock, $0.0001 par value, 18,125,051 shares authorized, 1,660,650 shares issued and 1,633,206 shares outstanding, actual; 18,125,051 shares authorized, 15,220,250 shares issued and 15,192,806 shares outstanding, pro forma
Common Stock, Value, Issued
Common stock, $0.0001 par value, 500,000,000 shares authorized as of March 31, 2026; 74,087,063 shares issued and 74,086,737 shares outstanding as of March 31, 2026; 500,000,000 shares authorized as of December 31, 2025; 73,001,766 shares issued and 73,001,350 shares outstanding as of December 31, 2025
Finance lease, commencement date range, start
Lessee, Finance Lease, Commencement Date Range, Start
Lessee, finance lease, commencement date range, start.
Payments on finance leases
Cash paid for amounts included in the measurement of lease liabilities, included in financing cash flows
Finance Lease, Principal Payments
Adverum Biotechnologies Inc
Adverum Biotechnologies Inc [Member]
Adverum Biotechnologies Inc.
Laboratory Equipment
Lab Equipment
Equipment Finance Lease [Member]
Thereafter
Lessee Operating Lease Liability Payments Due After Year Four
Lessee operating lease liability payments due after year four.
R Nolan Townsend.
R. Nolan Townsend
R Nolan Townsend [Member]
Milestone received
Milestone Received
Milestone received
Expected volatility
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Volatility Rate
Preferred stock, shares authorized
Convertible Preferred Stock Authorized
Preferred stock shares authorized
Percentage Of Ownership Considered for Warrant Exercise
Percentage of ownership considered for warrant exercise.
Percentage of ownership considered for warrant exercise
Employee Stock [Member]
Employee Stock Purchase Plan
Employee Stock Purchase Plan [Member]
Registrant Name
Entity Registrant Name
Gross Unrealized Losses
Debt Securities, Available-for-Sale, Accumulated Gross Unrealized Loss, before Tax
Payment to research and development
Payments to Acquire in Process Research and Development
Other Nonoperating Income (Expense)
Other Nonoperating Income (Expense), Total
Other expense, net
Subsequent Events [Abstract]
Net proceeds received from Private Placement.
Net Proceeds Received from Private Placement
Net proceeds from private placement
Income taxes
Income Tax Expense (Benefit)
Income Tax Expense (Benefit), Total
Measurement Frequency [Axis]
Treasury stock repurchase, Value
Treasury stock repurchase, Value
Treasury stock repurchase, Value
Shares repurchased value
Stock Repurchased During Period, Value
Proceeds from issuance of common stock
Proceeds from common stock issuances under 2023 ESPP
Gross proceeds received
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]
Fair Value Measurement Inputs and Valuation Techniques [Table Text Block]
Schedule of Fair Value Assumptions of Warrants
Entity Common Stock, Shares Outstanding
Concentrations of Credit Risk
Concentration Risk, Credit Risk, Policy [Policy Text Block]
Capital Expenditures Incurred But Not Yet Paid, Net of Paid Amount
Capital expenditures incurred but not yet paid, net of paid amount.
Property and equipment purchased in the prior period and paid in the current period, net of property and equipment purchased in the current period included in accounts payable
LX2020
Research and Development Expense LX2020
Research and development expense LX2020.
Accumulated Other Comprehensive Income (Loss), Net of Tax
Accumulated Other Comprehensive Income (Loss), Net of Tax, Total
Accumulated other comprehensive gain (loss)
Consolidation Items [Axis]
Consolidation Items [Axis]
Purchase of property and equipment
Payments to Acquire Property, Plant, and Equipment
Payments to Acquire Property, Plant, and Equipment, Total
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Grants in Period
Number of shares, granted
Total assets
Assets
Property, Plant and Equipment [Table]
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Weighted Average Remaining Contractual Term
Weighted average remaining contractual term, Options exercisable
Income Statement [Abstract]
Stock Based Compensation Expense
Share-Based Payment Arrangement [Policy Text Block]
Total aggregate monthly installment payment amount
Finance Lease Aggregate Monthly Installment Payment Amounts
Finance lease aggregate monthly installment payment amounts.
Shares issued
Sale of Stock, Number of Shares Issued in Transaction
Additional offering costs incurred related to issuance of common stock upon private placement offering
Stock Issued During Period Value New Issues Additional Offering Costs Incurred
Stock issued during period value new issues additional offering costs incurred.
Additional offering costs incurred related to issuance of common stock upon private placement offering
Number of common shares issued and sold
Stock Issued During Period, Shares, New Issues
Issuance of common stock, Shares
Convertible Preferred Stock Authorized
Convertible preferred stock, shares authorized
Temporary Equity, Shares Authorized
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Vested in Period
Number of shares, vested
Number of shares, vested
Number of shares vested
Business Combination [Abstract]
Net loss per common share, diluted
Net loss per share attributable to common stockholders, diluted
Earnings Per Share, Diluted
Earnings Per Share, Diluted, Total
Notes with outstanding principal exchanged
Debt Conversion, Original Debt, Amount
Schedule of Segment Reporting Information, by Segment [Table Text Block]
Summary Of Additional Information On Company's Net loss Including Segment Expenses
Operating Segments
Operating Segments [Member]
City Area Code
Stock Offering Gross Proceeds Percentage
Stock offering gross proceeds percentage.
Stock Offering Gross Proceeds Percentage
Other Comprehensive Income (Loss), Net of Tax
Total other comprehensive gain
Total other comprehensive gain (loss)
Commercialization milestones due
Commercialization Milestones Due
Commercialization milestones due.
Non-current portion of lease liabilities - finance
Finance Lease, Liability, Noncurrent
Leases
Leases of Lessee Disclosure [Text Block]
Weighted average remaining amortization term
Weighted Average Remaining Amortization Term (in years)
Finance Lease Weighted Average Remaining Amortization Term
Finance lease weighted average remaining amortization term.
Counterparty Name [Domain]
Variable lease expense
Variable Lease, Cost
Remaining lease terms
Operating Lease, Weighted Average Remaining Lease Term
Segment Reporting Information [Line Items]
Segment Reporting Information [Line Items]
Amounts reclassified from deposit liabilities upon the vesting of early-exercised stock options previously subject to repurchase, Value
Adjustments To Additional Paid In Capital Reclassification From Deposit Liability Share Based Compensation And Exercise Of Stock Options
Adjustments to additional paid in capital reclassification from deposit liability share based compensation and exercise of stock options.
Components of Equipment Finance Leases
Components of Equipment Finance Lease [Table Text Block]
Components of equipment Finance lease.
Letter of Credit
Letter of Credit [Member]
Payment to selling shareholders
Business Combination, Consideration Transferred, Equity Interest
Total property and equipment, net
Property and equipment, net
Property, Plant and Equipment, Net
Total property and equipment, net
Operating loss
Operating Income (Loss)
Research Collaboration Agreement
Research Collaboration Agreement [Member]
Research collaboration agreement.
Retained Earnings [Member]
Accumulated Deficit [Member]
Cash and Cash Equivalents [Axis]
Stock-based compensation expense
Stock based compensation expense
Share-Based Payment Arrangement, Noncash Expense
Share-Based Payment Arrangement, Noncash Expense, Total
Measurement Input, Price Volatility [Member]
Expected Volatility [Member]
Net of issuance costs
Underwriting discounts, placement agent fees, commissions and offering expenses
Payments of fees and offering costs
Components of Operating Lease
Components of Operating Lease [Table Text Block]
Components of operating lease.
Finance lease, commencement date range, end
Lessee, Finance Lease, Commencement Date Range, End
Lessee, finance lease, commencement date range, end.
Non-current portion of lease liabilities - operating
Operating Lease, Liability, Noncurrent
Level 1 [Member]
Fair Value, Inputs, Level 1 [Member]
Class of Stock [Line Items]
Cash Provided by (Used in) Financing Activity, Including Discontinued Operation
Net cash provided by financing activities
Cornell License Agreements
Cornell License Agreements [Member]
Cornell license agreements.
Operating lease agreement entered date
Operating Lease Agreement Entered Date
Operating lease agreement entered date.
Other income and expense
Nonoperating Income (Expense) [Abstract]
Debt Securities, Available-for-Sale [Table]
Entity Interactive Data Current
Statement of Income Location, Balance [Domain]
Cash flows from operating activities:
Cash Provided by (Used in) Operating Activity, Including Discontinued Operation [Abstract]
Furniture and Fixtures
Furniture and Fixtures [Member]
Accretion (Amortization) of Discounts and Premiums, Investments
Amortization of premium (accretion of discount) on investments in U.S. Treasury securities
Other programs
Research and Development Expense Other Programs
Research and development expense other programs.
Entity Tax Identification Number
Description of Business and Basis of Presentation
Organization, Consolidation and Presentation of Financial Statements Disclosure [Text Block]
First UCSD License Agreement
First UCSD License Agreement [Member]
First UCSD license agreement.
Proceeds from Issuance or Sale of Equity
Proceeds from Issuance or Sale of Equity, Total
Net proceeds from stock issuance
Local Phone Number
Thereafter
Lessee Operating Lease Liability Payments Due After Year Three
Lessee operating lease liability payments due after year three.
Denominator:
Weighted Average Number of Shares Outstanding, Diluted [Abstract]
Finance Lease, Liability, to be Paid, Year Two
2028
Deferred financing costs included in accounts payable and accrued expenses.
Deferred Financing Costs Included In Accounts Payable And Accrued Expenses
Deferred financing costs included in accounts payable and accrued expenses
Operating lease commencement date
Operating Lease Commencement Date
Operating lease commencement date.
Accounting Policies [Abstract]
Numerator:
Net Income (Loss) Attributable to Parent [Abstract]
Payment of license issue fee and initial data transfer fee
Payment of License Issue Fee and Initial Data Transfer Fee
License fee and initial data transfer fee
General and Administrative Expense [Abstract]
General and administrative expense
Lessee, Operating Lease, Liability, to be Paid, Year Four
2029
Class of Stock [Domain]
Labor and Related Expense
Lab-related costs and supplies
Number of shares available for future grants
Share-Based Compensation Arrangement by Share-Based Payment Award, Number of Shares Available for Grant
Unrecognized compensation expense, weighted-average period of recognition
Share-Based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Period for Recognition
Cash, Cash Equivalents, and Short-Term Investments
Cash, Cash Equivalents, and Short-Term Investments, Total
Cash and cash equivalents, including restricted cash and investments
Summary of Accrued Expenses and Other Current Liabilities
Schedule of Accounts Payable and Accrued Liabilities [Table Text Block]
Stock, Class of Stock [Table]
Entity Emerging Growth Company