Condensed Balance Sheets - USD ($) $ in Thousands	Mar. 31, 2026	Dec. 31, 2025
Current assets
Cash and cash equivalents	$ 22,190	$ 45,445
Short-term investments	148,702	145,499
Prepaid expenses and other current assets (Note 5)	3,132	4,464
Property and equipment held for sale (Note 4)	906	1,040
Total current assets	174,930	196,448
Property and equipment, net (Note 4)	2,664	2,940
Operating lease right-of-use assets (Note 15)	23,131	23,966
Restricted cash	1,482	1,482
Other non-current assets	389	392
Total assets	202,596	225,228
Current liabilities
Accounts payable	362	480
Accrued research and development	4,141	4,804
Accrued liabilities (Note 6)	4,143	9,634
Operating lease liabilities, current (Note 15)	1,713	1,447
Total current liabilities	10,359	16,365
Operating lease liabilities, non-current (Note 15)	27,071	27,658
Long-term debt (Note 7)	0	0
Total liabilities	37,430	44,023
Commitments and Contingencies (Note 14)
Stockholders’ equity
Preferred stock, $0.0001 par value per share; 10,000,000 shares authorized at March 31, 2026 and December 31, 2025, 300,000 shares designated as Series A Junior Participating Preferred Stock at March 31, 2026 and December 31, 2025; and none issued or outstanding at March 31, 2026 and December 31, 2025 (Note 8 and 10)	0	0
Common stock, $0.0001 par value per share; 300,000,000 shares authorized at March 31, 2026 and December 31, 2025; and 61,914,569 and 61,449,290 shares issued and outstanding at March 31, 2026 and December 31, 2025, respectively; (Note 9)	6	6
Additional paid-in capital	1,044,937	1,040,610
Accumulated deficit	(879,436)	(859,396)
Accumulated other comprehensive loss	(341)	(15)
Total stockholders’ equity	165,166	181,205
Total liabilities and stockholders’ equity	$ 202,596	$ 225,228

Accrued research and development expenses, current

No definition available.

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Namespace Prefix:	plrx_
Data Type:	xbrli:monetaryItemType
Balance Type:	credit
Period Type:	instant

- Definition

Carrying value as of the balance sheet date of liabilities incurred (and for which invoices have typically been received) and payable to vendors for goods and services received that are used in an entity's business. Used to reflect the current portion of the liabilities (due within one year or within the normal operating cycle if longer).