| Segment Information |
Segment InformationAbbVie operates as a single global business segment dedicated to the research and development, manufacturing, commercialization and sale of innovative medicines and therapies. This operating structure enables the Chief Executive Officer, as chief operating decision maker (CODM), to allocate resources and assess business performance on a global basis in order to achieve established long-term strategic goals. Consistent with this structure, a global research and development and supply chain organization is responsible for the discovery, manufacturing and supply of products. Commercial efforts that coordinate the marketing, sales and distribution of these products are organized by geographic region or therapeutic area. All of these activities are supported by a global corporate administrative staff. The determination of a single business segment is consistent with the consolidated financial information regularly reviewed by the CODM for purposes of assessing performance, allocating resources and planning and forecasting future periods. The CODM regularly reviews net revenues, net earnings and significant segment expenses and uses net earnings as its principal measure of segment profit or loss. Net earnings and significant segment expenses reviewed by the CODM are reported on the condensed consolidated statements of earnings for the periods ended March 31, 2026 and 2025. The CODM uses net earnings as its principal measure of segment profit or loss to compare past financial performance with current performance and analyze underlying business performance and trends. The CODM does not use segment assets to make decisions regarding resources; therefore, the total asset disclosure has not been included. The following table details AbbVie’s worldwide net revenues: | | | | | | | | | | | | | | | | | | | | | | | Three months ended March 31, | | | | | | | | | | | | | | | | (in millions) | | 2026 | | 2025 | | | | | | | | Immunology | | | | | | | | | | | Skyrizi | United States | $ | 3,775 | | | $ | 2,919 | | | | | | | | | International | 708 | | | 506 | | | | | | | | | Total | $ | 4,483 | | | $ | 3,425 | | | | | | | | | Rinvoq | United States | $ | 1,405 | | | $ | 1,220 | | | | | | | | | International | 714 | | | 498 | | | | | | | | | Total | $ | 2,119 | | | $ | 1,718 | | | | | | | | | Humira | United States | $ | 357 | | | $ | 744 | | | | | | | | | International | 331 | | | 377 | | | | | | | | | Total | $ | 688 | | | $ | 1,121 | | | | | | | | | Neuroscience | | | | | | | | | | | Vraylar | United States | $ | 902 | | | $ | 763 | | | | | | | | | International | 3 | | | 2 | | | | | | | | | Total | $ | 905 | | | $ | 765 | | | | | | | | | Botox Therapeutic | United States | $ | 842 | | | $ | 723 | | | | | | | | | International | 167 | | | 143 | | | | | | | | | Total | $ | 1,009 | | | $ | 866 | | | | | | | | | Ubrelvy | United States | $ | 330 | | | $ | 233 | | | | | | | | | International | 9 | | | 7 | | | | | | | | | Total | $ | 339 | | | $ | 240 | | | | | | | | | Qulipta | United States | $ | 250 | | | $ | 172 | | | | | | | | | International | 46 | | | 21 | | | | | | | | | Total | $ | 296 | | | $ | 193 | | | | | | | | | Vyalev | United States | $ | 89 | | | $ | 6 | | | | | | | | | International | 112 | | | 57 | | | | | | | | | Total | $ | 201 | | | $ | 63 | | | | | | | | | Other Neuroscience | United States | $ | 46 | | | $ | 75 | | | | | | | | | International | 79 | | | 80 | | | | | | | | | Total | $ | 125 | | | $ | 155 | | | | | | | | | Oncology | | | | | | | | | | | Venclexta | United States | $ | 341 | | | $ | 312 | | | | | | | | | International | 429 | | | 353 | | | | | | | | | Total | $ | 770 | | | $ | 665 | | | | | | | |
| | | | | | | | | | | | | | | | | | | | | | | Three months ended March 31, | | | | | | | | | | | | | | | | (in millions) | | 2026 | | 2025 | | | | | | | | Imbruvica | United States | $ | 332 | | | $ | 529 | | | | | | | | | Collaboration revenues | 224 | | | 209 | | | | | | | | | Total | $ | 556 | | | $ | 738 | | | | | | | | | Elahere | United States | $ | 160 | | | $ | 165 | | | | | | | | | International | 38 | | | 14 | | | | | | | | | Total | $ | 198 | | | $ | 179 | | | | | | | | | Epkinly | Collaboration revenues | $ | 51 | | | $ | 36 | | | | | | | | | International | 32 | | | 15 | | | | | | | | | Total | $ | 83 | | | $ | 51 | | | | | | | | | Other Oncology | United States | $ | 24 | | | $ | — | | | | | | | | | Aesthetics | | | | | | | | | | | Botox Cosmetic | United States | $ | 371 | | | $ | 295 | | | | | | | | | International | 297 | | | 261 | | | | | | | | | Total | $ | 668 | | | $ | 556 | | | | | | | | | Juvederm Collection | United States | $ | 85 | | | $ | 75 | | | | | | | | | International | 147 | | | 156 | | | | | | | | | Total | $ | 232 | | | $ | 231 | | | | | | | | | Other Aesthetics | United States | $ | 248 | | | $ | 270 | | | | | | | | | International | 38 | | | 45 | | | | | | | | | Total | $ | 286 | | | $ | 315 | | | | | | | | | Other Key Products | | | | | | | | | | | Mavyret | United States | $ | 183 | | | $ | 142 | | | | | | | | | International | 168 | | | 164 | | | | | | | | | Total | $ | 351 | | | $ | 306 | | | | | | | | | Creon | United States | $ | 361 | | | $ | 355 | | | | | | | | Linzess | United States | $ | 272 | | | $ | 139 | | | | | | | | | International | 11 | | | 9 | | | | | | | | | Total | $ | 283 | | | $ | 148 | | | | | | | | | All other | | $ | 1,025 | | | $ | 1,253 | | | | | | | | | Total net revenues | $ | 15,002 | | | $ | 13,343 | | | | | | | |
See the following for additional information about certain income and expenses included in net earnings: intangible assets amortization expense (Note 6), change in fair value of contingent consideration (Note 7), interest income and expense (Note 2), depreciation expense (Note 2), litigation matters (Note 11) and income tax expense (Note 10).
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