Note 4 - Balance Sheet Components 1 (Tables)

3 Months Ended

12 Months Ended

Mar. 31, 2026

Dec. 31, 2025

Notes Tables

Cash, Cash Equivalent, and Investment [Table Text Block]

		*Amortized*				*Gross Unrealized*								*Estimated*				*Cash and Cash*				*Short-Term*
		*Cost*				*Gains*				*Losses*				*Fair Value*				*Equivalents*				*Investments*
March 31, 2026
Cash at banks		$	3,837			$	—			$	—			$	3,837			$	3,837			$	—
Money market funds			44,121				—				—				44,121				44,121				—
U.S. Treasury securities			4,190				—				(2	)			4,188				2,788				1,400
Commercial paper			8,881				—				(5	)			8,876				—				8,876
Total		$	61,029			$	—			$	(7	)		$	61,022			$	50,746			$	10,276

		*Amortized*				*Gross Unrealized*								*Estimated*				*Cash and Cash*				*Short-Term*
		*Cost*				*Gains*				*Losses*				*Fair Value*				*Equivalents*				*Investments*
December 31, 2025
Cash at banks		$	3,583			$	—			$	—			$	3,583			$	3,583			$	—
Money market funds			46,164				—				—				46,164				46,164				—
U.S. Treasury securities			14,063				1				(4	)			14,060				4,067				9,993
Total		$	63,810			$	1			$	(4	)		$	63,807			$	53,814			$	9,993

		*Amortized*				*Gross Unrealized*								*Estimated*				*Cash and Cash*				*Short-Term*
		*Cost*				*Gains*				*Losses*				*Fair Value*				*Equivalents*				*Investments*
December 31, 2025
Cash at banks		$	3,583			$	—			$	—			$	3,583			$	3,583			$	—
Money market funds			46,164				—				—				46,164				46,164				—
U.S. Treasury securities			14,063				1				(4	)			14,060				4,067				9,993
Total		$	63,810			$	1			$	(4	)		$	63,807			$	53,814			$	9,993

		*Amortized*				*Gross Unrealized*								*Estimated*				*Cash and Cash*				*Short-Term*
		*Cost*				*Gains*				*Losses*				*Fair Value*				*Equivalents*				*Investments*
December 31, 2024
Cash at banks		$	8,740			$	—			$	—			$	8,740			$	8,740			$	—
Money market funds			16,489				—				—				16,489				16,489				—
U.S. Treasury securities			23,802				7				(4	)			23,805				—				23,805
Commercial paper			2,688				1				—				2,689				—				2,689
Total		$	51,719			$	8			$	(4	)		$	51,723			$	25,229			$	26,494

Deferred Costs, Capitalized, Prepaid, and Other Assets Disclosure [Table Text Block]

		*March 31, 2026*				*December 31, 2025*

Prepaid clinical and manufacturing expenses		$	10,869			$	18,920
Prepaid insurance			98				168
Prepaid rent			562				539
Other prepaid			965				677
Other current assets			614				667
Prepaid expenses and other current assets		$	13,108			$	20,971

		*December 31, 2025*				*December 31, 2024*

Prepaid clinical and manufacturing expenses		$	18,920			$	1,998
Prepaid insurance			168				282
Prepaid rent			539				521
Other prepaid			677				1,449
Other current assets			667				318
Prepaid expenses and other current assets		$	20,971			$	4,568

Property, Plant, and Equipment [Table Text Block]

		*March 31, 2026*				*December 31, 2025*

Laboratory equipment		$	13,963			$	14,005
Office and computer equipment			1,158				1,142
Leasehold improvements			3,929				3,929
Construction in progress			335				158
Total property and equipment			19,385				19,234
Less: accumulated depreciation			(14,558	)			(13,801	)
Property and equipment, net		$	4,827			$	5,433

		*December 31, 2025*				*December 31, 2024*

Laboratory equipment		$	14,005			$	13,806
Office and computer equipment			1,142				1,140
Leasehold improvements			3,929				4,107
Construction in progress			158				160
Total property and equipment			19,234				19,213
Less: accumulated depreciation			(13,801	)			(10,508	)
Property and equipment, net		$	5,433			$	8,705

Intangible Asset, Finite-Lived [Table Text Block]

		*March 31, 2026*				*December 31, 2025*

Developed technology		$	5,000			$	5,000
Intellectual property			80				80
Total cost			5,080				5,080
Less: accumulated amortization			(2,437	)			(2,254	)
Intangible assets, net		$	2,643			$	2,826

		*December 31, 2025*				*December 31, 2024*

Developed technology		$	5,000			$	5,000
Intellectual property			80				80
Total cost			5,080				5,080
Less: accumulated amortization			(2,254	)			(1,523	)
Intangible assets, net		$	2,826			$	3,557

Intangible Asset, Finite-Lived, and Capitalized Cost, Software to be Sold, Leased, or Marketed, Estimated Amortization Expense [Table Text Block]

Year Ending December 31,		*Amount*
2026 (nine months remaining)		$	549
2027			731
2028			727
2029			636
Total		$	2,643

Year Ending December 31,		Amount
2026		$	732
2027			731
2028			727
2029			636
Total		$	2,826

Contract with Customer, Contract Asset, Contract Liability, and Receivable [Table Text Block]

		*March 31, 2026*				*December 31, 2025*

Balance at beginning of period		$	68			$	65,400
Revenue recognized			(45	)			(65,513	)
Amounts collected or invoiced			—				181
Balance at end of period		$	23			$	68

		*March 31, 2026*				*December 31, 2025*

Balance at beginning of period		$	14,976			$	—
Revenue recognized for collaboration			(2,815	)			(2,108	)
Amounts collected or invoiced			—				17,084
Total deferred collaboration revenue			12,161				14,976
Current portion			(11,716	)			(12,952	)
Long-term portion		$	445			$	2,024

		*December 31, 2025*				*December 31, 2024*

Balance at beginning of period		$	65,400			$	—
Revenue recognized			(65,513	)			—
Amounts collected or invoiced			181				65,400
Balance at end of period		$	68			$	65,400

		*December 31, 2025*

Balance at beginning of period		$	—
Revenue recognized for collaboration			(2,108	)
Amounts collected or invoiced			17,084
Total deferred collaboration revenue			14,976
Current portion			(12,952	)
Long-term portion		$	2,024

Schedule of Accrued Liabilities [Table Text Block]

		*March 31, 2026*				*December 31, 2025*

Accrued compensation		$	2,259			$	4,244
Accrued clinical and manufacturing expenses			32,728				42,455
Accrued professional and consulting services			718				552
Other liabilities, current portion			821				628
Total		$	36,526			$	47,879

		*December 31, 2025*				*December 31, 2024*

Accrued compensation		$	4,244			$	5,087
Accrued clinical and manufacturing expenses			42,455				5,134
Accrued professional and consulting services			552				623
Other liabilities, current portion			628				534
Total		$	47,879			$	11,378