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  <xsd:element abstract="true" id="atxi_Atx04Member" name="Atx04Member" nillable="true" substitutionGroup="xbrli:item" type="dtr-types:domainItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="atxi_AvenueBaergicFoundersAgreementMember" name="AvenueBaergicFoundersAgreementMember" nillable="true" substitutionGroup="xbrli:item" type="dtr-types:domainItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="atxi_BaergicbioIncMember" name="BaergicbioIncMember" nillable="true" substitutionGroup="xbrli:item" type="dtr-types:domainItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="atxi_ClassAPreferredSharesMember" name="ClassAPreferredSharesMember" nillable="true" substitutionGroup="xbrli:item" type="dtr-types:domainItemType" xbrli:periodType="duration"/>
  <xsd:element id="atxi_ClassOfWarrantOrRightAggregateIntrinsicValue" name="ClassOfWarrantOrRightAggregateIntrinsicValue" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="credit" xbrli:periodType="duration"/>
  <xsd:element id="atxi_ClassOfWarrantOrRightExpiredDuringPeriod" name="ClassOfWarrantOrRightExpiredDuringPeriod" nillable="true" substitutionGroup="xbrli:item" type="xbrli:sharesItemType" xbrli:periodType="duration"/>
  <xsd:element id="atxi_ClassOfWarrantOrRightExpiredDuringPeriodWeightedAverageExercisePrice" name="ClassOfWarrantOrRightExpiredDuringPeriodWeightedAverageExercisePrice" nillable="true" substitutionGroup="xbrli:item" type="dtr-types:perShareItemType" xbrli:periodType="duration"/>
  <xsd:element id="atxi_CommissionFeePercentFee" name="CommissionFeePercentFee" nillable="true" substitutionGroup="xbrli:item" type="dtr-types:percentItemType" xbrli:periodType="duration"/>
  <xsd:element id="atxi_CommonStockIssuableShares" name="CommonStockIssuableShares" nillable="true" substitutionGroup="xbrli:item" type="xbrli:sharesItemType" xbrli:periodType="instant"/>
  <xsd:element id="atxi_CommonStockIssuedToFortressValue" name="CommonStockIssuedToFortressValue" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="debit" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="atxi_CommonStockWarrantLiabilitiesTable" name="CommonStockWarrantLiabilitiesTable" nillable="true" substitutionGroup="xbrldt:hypercubeItem" type="xbrli:stringItemType" xbrli:periodType="duration"/>
  <xsd:element id="atxi_CommonStockWarrantLiabilitiesTextBlock" name="CommonStockWarrantLiabilitiesTextBlock" nillable="true" substitutionGroup="xbrli:item" type="dtr-types:textBlockItemType" xbrli:periodType="duration"/>
  <xsd:element id="atxi_ContingentFeeMaximumAllowableAmount" name="ContingentFeeMaximumAllowableAmount" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="credit" xbrli:periodType="instant"/>
  <xsd:element id="atxi_ContingentFeePercentageOfProceedsOfFutureFinancings" name="ContingentFeePercentageOfProceedsOfFutureFinancings" nillable="true" substitutionGroup="xbrli:item" type="dtr-types:percentItemType" xbrli:periodType="duration"/>
  <xsd:element id="atxi_ContractualObligationContractualMilestoneAmount" name="ContractualObligationContractualMilestoneAmount" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="credit" xbrli:periodType="instant"/>
  <xsd:element id="atxi_ContractualObligationMaximumFuturePayments" name="ContractualObligationMaximumFuturePayments" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="credit" xbrli:periodType="instant"/>
  <xsd:element abstract="true" id="atxi_DeferredRestrictedStockUnitsMember" name="DeferredRestrictedStockUnitsMember" nillable="true" substitutionGroup="xbrli:item" type="dtr-types:domainItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="atxi_DocumentAndEntityInformation" name="DocumentAndEntityInformation" nillable="true" substitutionGroup="xbrli:item" type="xbrli:stringItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="atxi_DukeUniversityMember" name="DukeUniversityMember" nillable="true" substitutionGroup="xbrli:item" type="dtr-types:domainItemType" xbrli:periodType="duration"/>
  <xsd:element id="atxi_EligibleTerminationPaymentsCommercialSalesMilestones" name="EligibleTerminationPaymentsCommercialSalesMilestones" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="debit" xbrli:periodType="instant"/>
  <xsd:element id="atxi_EligibleTerminationPaymentsDevelopmentAndRegulatoryMilestones" name="EligibleTerminationPaymentsDevelopmentAndRegulatoryMilestones" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="debit" xbrli:periodType="instant"/>
  <xsd:element id="atxi_EligibleTerminationPaymentsRoyaltyPercentageOnNetSales" name="EligibleTerminationPaymentsRoyaltyPercentageOnNetSales" nillable="true" substitutionGroup="xbrli:item" type="dtr-types:percentItemType" xbrli:periodType="instant"/>
  <xsd:element id="atxi_ExcessInNetAssetsValue" name="ExcessInNetAssetsValue" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="debit" xbrli:periodType="instant"/>
  <xsd:element abstract="true" id="atxi_FortressBiotechIncMember" name="FortressBiotechIncMember" nillable="true" substitutionGroup="xbrli:item" type="dtr-types:domainItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="atxi_FortressMember" name="FortressMember" nillable="true" substitutionGroup="xbrli:item" type="dtr-types:domainItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="atxi_FoundersAgreementAndManagementServicesAgreementMember" name="FoundersAgreementAndManagementServicesAgreementMember" nillable="true" substitutionGroup="xbrli:item" type="dtr-types:domainItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="atxi_GeneralAndAdministrativeMember" name="GeneralAndAdministrativeMember" nillable="true" substitutionGroup="xbrli:item" type="dtr-types:domainItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="atxi_IncentiveStockOptionsMember" name="IncentiveStockOptionsMember" nillable="true" substitutionGroup="xbrli:item" type="dtr-types:domainItemType" xbrli:periodType="duration"/>
  <xsd:element id="atxi_IncreaseInAnnualConsultingFee" name="IncreaseInAnnualConsultingFee" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="credit" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="atxi_InsiderTradingArrangementsTable" name="InsiderTradingArrangementsTable" nillable="true" substitutionGroup="xbrldt:hypercubeItem" type="xbrli:stringItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="atxi_InvagenPharmaceuticalsIncMember" name="InvagenPharmaceuticalsIncMember" nillable="true" substitutionGroup="xbrli:item" type="dtr-types:domainItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="atxi_IvTramadolMember" name="IvTramadolMember" nillable="true" substitutionGroup="xbrli:item" type="dtr-types:domainItemType" xbrli:periodType="duration"/>
  <xsd:element id="atxi_LicenseAgreementDisclosureTextBlock" name="LicenseAgreementDisclosureTextBlock" nillable="true" substitutionGroup="xbrli:item" type="dtr-types:textBlockItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="atxi_LicensesSupplierAgreementsTable" name="LicensesSupplierAgreementsTable" nillable="true" substitutionGroup="xbrldt:hypercubeItem" type="xbrli:stringItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="atxi_ManagementServicesAgreementMember" name="ManagementServicesAgreementMember" nillable="true" substitutionGroup="xbrli:item" type="dtr-types:domainItemType" xbrli:periodType="duration"/>
  <xsd:element id="atxi_NoncontrollingInterestsPolicyTextBlock" name="NoncontrollingInterestsPolicyTextBlock" nillable="true" substitutionGroup="xbrli:item" type="dtr-types:textBlockItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="atxi_NoteToFinancialStatementDetailsTextual" name="NoteToFinancialStatementDetailsTextual" nillable="true" substitutionGroup="xbrli:item" type="xbrli:stringItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="atxi_NotesToFinancialStatements" name="NotesToFinancialStatements" nillable="true" substitutionGroup="xbrli:item" type="xbrli:stringItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="atxi_NotesToFinancialStatementsAbstract" name="NotesToFinancialStatementsAbstract" nillable="true" substitutionGroup="xbrli:item" type="xbrli:stringItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="atxi_October2022WarrantsMember" name="October2022WarrantsMember" nillable="true" substitutionGroup="xbrli:item" type="dtr-types:domainItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="atxi_OrganizationPlanOfBusinessOperationsTable" name="OrganizationPlanOfBusinessOperationsTable" nillable="true" substitutionGroup="xbrldt:hypercubeItem" type="xbrli:stringItemType" xbrli:periodType="duration"/>
  <xsd:element id="atxi_PaymentOfContingentFee" name="PaymentOfContingentFee" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="credit" xbrli:periodType="duration"/>
  <xsd:element id="atxi_PaymentsUponTerminationOfAgreement" name="PaymentsUponTerminationOfAgreement" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="credit" xbrli:periodType="duration"/>
  <xsd:element id="atxi_PercentageConsideredForTheCalculationOfOnetimeFee" name="PercentageConsideredForTheCalculationOfOnetimeFee" nillable="true" substitutionGroup="xbrli:item" type="dtr-types:percentItemType" xbrli:periodType="instant"/>
  <xsd:element id="atxi_PercentageOfAdditionalConsiderationOfEquityFee" name="PercentageOfAdditionalConsiderationOfEquityFee" nillable="true" substitutionGroup="xbrli:item" type="dtr-types:percentItemType" xbrli:periodType="instant"/>
  <xsd:element id="atxi_PercentageOfEquityFee" name="PercentageOfEquityFee" nillable="true" substitutionGroup="xbrli:item" type="dtr-types:percentItemType" xbrli:periodType="instant"/>
  <xsd:element id="atxi_PercentageOfEquityOrDebtFnancing" name="PercentageOfEquityOrDebtFnancing" nillable="true" substitutionGroup="xbrli:item" type="dtr-types:percentItemType" xbrli:periodType="instant"/>
  <xsd:element id="atxi_PercentageOfFullydilutedOutstandingEquity" name="PercentageOfFullydilutedOutstandingEquity" nillable="true" substitutionGroup="xbrli:item" type="dtr-types:percentItemType" xbrli:periodType="instant"/>
  <xsd:element abstract="true" id="atxi_PolicyTable" name="PolicyTable" nillable="true" substitutionGroup="xbrldt:hypercubeItem" type="xbrli:stringItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="atxi_PolpharmaMember" name="PolpharmaMember" nillable="true" substitutionGroup="xbrli:item" type="dtr-types:domainItemType" xbrli:periodType="duration"/>
  <xsd:element id="atxi_ResearchAndDevelopmentExpenseLicensesAcquired" name="ResearchAndDevelopmentExpenseLicensesAcquired" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="debit" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="atxi_ResearchAndDevelopmentMember" name="ResearchAndDevelopmentMember" nillable="true" substitutionGroup="xbrli:item" type="dtr-types:domainItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="atxi_RevogenexLicenseMember" name="RevogenexLicenseMember" nillable="true" substitutionGroup="xbrli:item" type="dtr-types:domainItemType" xbrli:periodType="duration"/>
  <xsd:element id="atxi_ServiceProvidedExpenseRecordedPercentage" name="ServiceProvidedExpenseRecordedPercentage" nillable="true" substitutionGroup="xbrli:item" type="dtr-types:percentItemType" xbrli:periodType="duration"/>
  <xsd:element id="atxi_TerminationPaymentsReceivable" name="TerminationPaymentsReceivable" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="debit" xbrli:periodType="instant"/>
  <xsd:element id="atxi_TerminationPaymentsReceivableNet" name="TerminationPaymentsReceivableNet" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="debit" xbrli:periodType="instant"/>
  <xsd:element abstract="true" id="atxi_TwoThousandFifteenIncentivePlanMember" name="TwoThousandFifteenIncentivePlanMember" nillable="true" substitutionGroup="xbrli:item" type="dtr-types:domainItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="atxi_statement-statement-note-2-significant-accounting-policies-antidilutive-securities-details" name="statement-statement-note-2-significant-accounting-policies-antidilutive-securities-details" nillable="true" substitutionGroup="xbrli:item" type="xbrli:stringItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="atxi_statement-statement-note-2-significant-accounting-policies-tables" name="statement-statement-note-2-significant-accounting-policies-tables" nillable="true" substitutionGroup="xbrli:item" type="xbrli:stringItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="atxi_statement-statement-note-5-accounts-payable-and-accrued-expenses-accounts-payable-and-accrued-expenses-details" name="statement-statement-note-5-accounts-payable-and-accrued-expenses-accounts-payable-and-accrued-expenses-details" nillable="true" substitutionGroup="xbrli:item" type="xbrli:stringItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="atxi_statement-statement-note-5-accounts-payable-and-accrued-expenses-tables" name="statement-statement-note-5-accounts-payable-and-accrued-expenses-tables" nillable="true" substitutionGroup="xbrli:item" type="xbrli:stringItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="atxi_statement-statement-note-7-stockholders-equity-restricted-stock-unit-and-award-activity-details" name="statement-statement-note-7-stockholders-equity-restricted-stock-unit-and-award-activity-details" nillable="true" substitutionGroup="xbrli:item" type="xbrli:stringItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="atxi_statement-statement-note-7-stockholders-equity-stock-warrants-details" name="statement-statement-note-7-stockholders-equity-stock-warrants-details" nillable="true" substitutionGroup="xbrli:item" type="xbrli:stringItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="atxi_statement-statement-note-7-stockholders-equity-stockbased-compensation-expense-details" name="statement-statement-note-7-stockholders-equity-stockbased-compensation-expense-details" nillable="true" substitutionGroup="xbrli:item" type="xbrli:stringItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="atxi_statement-statement-note-7-stockholders-equity-summary-of-stock-option-activity-details" name="statement-statement-note-7-stockholders-equity-summary-of-stock-option-activity-details" nillable="true" substitutionGroup="xbrli:item" type="xbrli:stringItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="atxi_statement-statement-note-7-stockholders-equity-tables" name="statement-statement-note-7-stockholders-equity-tables" nillable="true" substitutionGroup="xbrli:item" type="xbrli:stringItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="atxi_statement-statement-note-8-common-stock-warrant-liabilities-fair-value-of-warrants-liabilities-measured-within-level-3-on-recurring-basis-details" name="statement-statement-note-8-common-stock-warrant-liabilities-fair-value-of-warrants-liabilities-measured-within-level-3-on-recurring-basis-details" nillable="true" substitutionGroup="xbrli:item" type="xbrli:stringItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="atxi_statement-statement-note-8-common-stock-warrants-schedule-of-warrants-under-monte-carlo-simulation-and-blackscholes-model-details" name="statement-statement-note-8-common-stock-warrants-schedule-of-warrants-under-monte-carlo-simulation-and-blackscholes-model-details" nillable="true" substitutionGroup="xbrli:item" type="xbrli:stringItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="atxi_statement-statement-note-8-common-stock-warrants-tables" name="statement-statement-note-8-common-stock-warrants-tables" nillable="true" substitutionGroup="xbrli:item" type="xbrli:stringItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="atxi_statement-statement-significant-accounting-policies-policies" name="statement-statement-significant-accounting-policies-policies" nillable="true" substitutionGroup="xbrli:item" type="xbrli:stringItemType" xbrli:periodType="duration"/>
</xsd:schema>
