Cover [Abstract] Document Information [Table] Document Information [Line Items] Document Type Document Quarterly Report Document Period End Date Document Transition Report Securities Act File Number Entity Registrant Name Entity Incorporation, State or Country Code Entity Tax Identification Number Entity Address, Address Line One Entity Address, Address Line Two Entity Address, City or Town Entity Address, State or Province Entity Address, Postal Zip Code City Area Code Local Phone Number Title of 12(b) Security Trading Symbol Security Exchange Name Entity Current Reporting Status Entity Interactive Data Current Entity Filer Category Entity Small Business Entity Emerging Growth Company Entity Shell Company Entity Common Stock, Shares Outstanding Entity Central Index Key Current Fiscal Year End Date Document Fiscal Year Focus Document Fiscal Period Focus Amendment Flag Statement of Financial Position [Abstract] Statement [Table] Statement [Line Items] Assets [Abstract] Assets, Current [Abstract] Current assets: Cash and Cash Equivalent Cash and cash equivalents Debt Securities, Available-for-Sale, Current Short-term marketable securities Represents the amount receivable from collaboration partners under the collaborative arrangement. Receivables from Collaboration Partners Receivables from collaborative arrangements Receivables from Milestone and Royalty Assets, Current Receivables from Milestone and Royalty Assets, Current Receivables from milestones and royalty assets Other Prepaid Expense, Current Other prepaid and current assets Assets, Current Total current assets Debt Securities, Available-for-Sale, Noncurrent Long-term marketable securities Property, Plant and Equipment, Net Property and equipment, net Operating Lease, Right-of-Use Asset Operating lease assets Restricted Cash, Noncurrent Restricted cash Other Assets, Noncurrent Other assets Assets Total assets Liabilities and Equity [Abstract] Liabilities, Current [Abstract] Current liabilities: Accounts Payable, Current Accounts payable Employee-related Liabilities, Current Accrued personnel-related expenses Carrying value as of the balance sheet date of obligations incurred through that date and payable for obligations related to clinical development services. Used to reflect the current portion of the liabilities (due within one year or within the normal operating cycle if longer). Accrued Clinical and Development Expenses, Current Accrued clinical and development expenses Accrued General and Administrative Expenses Accrued General and Administrative Expenses Accrued general and administrative expenses Operating Lease, Liability, Current Operating lease liabilities Accrued Income Taxes, Current Income tax payable Other Accrued Liabilities, Current Other accrued liabilities Liabilities, Current Total current liabilities Operating Lease, Liability, Noncurrent Long-term operating lease liabilities The amount of future royalty payment contingencies. Future Royalty Payment Contingencies Future royalty payment contingency Unrecognized Tax Benefits, Noncurrent Unrecognized Tax Benefits, Noncurrent Unrecognized tax benefits Other Liabilities, Noncurrent Other long-term liabilities Commitments and Contingencies Commitments and contingencies (Note 11) Equity, Attributable to Parent [Abstract] Shareholders' Equity Preferred Stock, Value, Issued Preferred shares, $0.00001 par value per share: 230 shares authorized, no shares issued or outstanding Common Stock, Value, Issued Ordinary shares, $0.00001 par value per share: 200,000 shares authorized; 51,515 and 51,069 shares issued and outstanding at March 31, 2026 and December 31, 2025, respectively Additional Paid in Capital Additional paid-in capital Accumulated Other Comprehensive Income (Loss), Net of Tax Accumulated other comprehensive income Retained Earnings (Accumulated Deficit) Accumulated deficit Equity, Attributable to Parent Total shareholders' equity Liabilities and Equity Total liabilities and shareholders' equity Stockholders' Equity, Number of Shares, Par Value and Other Disclosure [Abstract] Preferred Stock, Number of Shares, Par Value and Other Disclosure [Abstract] Preferred shares Preferred Stock, Par or Stated Value Per Share Preferred shares, par value (in dollars per share) Preferred Stock, Shares Authorized Preferred shares, shares authorized (in shares) Preferred Stock, Shares Issued Preferred shares, shares issued (in shares) Preferred Stock, Shares Outstanding Preferred shares, outstanding shares (in shares) Common Stock, Number of Shares, Par Value and Other Disclosure [Abstract] Ordinary shares Common Stock, Par or Stated Value Per Share Ordinary shares, par value (in dollars per share) Common Stock, Shares Authorized Ordinary shares, shares authorized (in shares) Common Stock, Shares, Issued Balances (in shares) Balances (in shares) Ordinary shares, shares issued (in shares) Common Stock, Shares, Outstanding Ordinary shares, shares outstanding (in shares) Income Statement [Abstract] Revenues [Abstract] Revenues: Revenue from Contract with Customer, Excluding Assessed Tax Total revenues Revenue from Contract with Customer, Product and Service [Extensible Enumeration] Revenue from Contract with Customer, Product and Service Operating Expenses [Abstract] Expenses: Research and Development Expense Research and development Selling, General and Administrative Expense Selling, general and administrative Restructuring and Related Expenses Restructuring and Related Expenses Restructuring expenses Total restructuring expenses Restructuring expenses (including share-based compensation) Operating Expenses Total expenses Operating Income (Loss) Loss from operations Loss from operations Interest Expense, Nonoperating Interest expense (non-cash) Other Nonoperating Income (Expense) Interest and other income, net Interest and other income, net Income (Loss) from Continuing Operations before Income Taxes, Noncontrolling Interest Loss before income taxes Income Tax Expense (Benefit) Provision for income tax benefit Provision for income tax expense Net Income (Loss) Attributable to Parent Net loss Net loss Net loss Earnings Per Share, Diluted [Abstract] Net loss per share: Earnings Per Share, Basic Net loss per share - basic (in dollars per share) Earnings Per Share, Diluted Net loss per share - diluted (in dollars per share) Weighted Average Number of Shares Outstanding, Basic Shares used to compute net income loss per share - basic (in shares) Weighted-average ordinary shares outstanding - basic (in shares) Weighted Average Number of Shares Outstanding, Diluted Weighted-average ordinary shares outstanding - diluted (in shares) Shares used to compute net income loss per share - diluted (in shares) Statement of Income Location, Balance [Axis] Statement of Income Location, Balance [Domain] Research and Development Expense [Member] Research and Development Selling, General and Administrative Expenses [Member] Selling, General and Administrative Restructuring and Related Expenses [Member] Restructuring and Related Expenses [Member] Restructuring Expenses Compensation Items [Abstract] Income Statement Compensation Expense Items [Abstract] Share-Based Compensation Expense Share-Based Payment Arrangement, Expense Share-based compensation expense Restructuring, Settlement and Impairment Provisions [Abstract] Restructuring Charges [Abstract] Restructuring Charges Restructuring Charges Cash-related expenses Net accruals Restructuring Charges, Noncash Related Expenses Restructuring Charges, Noncash Related Expenses Non-cash related expenses Non-cash related expenses Statement of Comprehensive Income [Abstract] Net Income (Loss) Attributable to Parent [Abstract] Net loss Other Comprehensive Income (Loss), Net of Tax, Portion Attributable to Parent [Abstract] Other comprehensive income: OCI, Debt Securities, Available-for-Sale, Unrealized Holding Gain (Loss), before Adjustment, after Tax Net unrealized loss on marketable securities Net unrealized loss on available-for-sale investments Comprehensive Income (Loss), Net of Tax, Attributable to Parent Total comprehensive loss Statement of Stockholders' Equity [Abstract] Equity Components [Axis] Equity Component [Domain] Parent [Member] Common Stock [Member] Ordinary Shares Additional Paid-in Capital [Member] Additional Paid-In Capital AOCI Attributable to Parent [Member] Accumulated Other Comprehensive Income (Loss) Retained Earnings [Member] Accumulated Deficit Increase (Decrease) in Stockholders' Equity [Roll Forward] Increase (Decrease) in Stockholders' Equity Equity, Including Portion Attributable to Noncontrolling Interest Balances Balances Stock Issued During Period, Value, New Issues Proceeds from the sale of ordinary shares Stock Issued During Period, Shares, New Issues Proceeds from the sale of ordinary shares (in shares) APIC, Share-Based Payment Arrangement, Increase for Cost Recognition Employee share-based compensation expense Stock Issued During Period, Value, Restricted Stock Award, Gross Issuance of restricted shares Stock Issued During Period, Shares, Restricted Stock Award, Gross Issuance of restricted shares (in shares) Stock Issued During Period, Value, Stock Options Exercised Option exercises Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercises in Period Exercised (in shares) Option exercises (in shares) Share-Based Payment Arrangement, Decrease for Tax Withholding Obligation Repurchase of shares to satisfy tax withholding Share-Based Payment Arrangement, Shares Withheld for Tax Withholding Obligation Repurchase of shares to satisfy tax withholding (in shares) Statement of Cash Flows [Abstract] Cash Provided by (Used in) Operating Activity, Continuing Operation [Abstract] Operating activities Net Income (Loss), Including Portion Attributable to Noncontrolling Interest Net loss Adjustment to Reconcile Net Income to Cash Provided by (Used in) Operating Activity [Abstract] Adjustments to reconcile net loss to net cash provided by operating activities: Other Depreciation and Amortization Depreciation and amortization Amortization and Accretion Income Amortization and Accretion Income Amortization and accretion on investment securities, net The accretion of interest on liability for sale of future royalties. Interest Accretion on Future Royalty Payment Contingencies Future royalty payment contingency interest accretion Share-Based Payment Arrangement, Noncash Expense Share-based compensation Operating Lease, Right-of-Use Asset, Periodic Reduction Amortization of right-of-use assets Deferred Income Taxes and Tax Credits Deferred income taxes Other Noncash Income (Expense) Other Adjustment to Reconcile Net Income to Cash Provided by (Used in) Operating Activity, Increase (Decrease) in Operating Capital [Abstract] Changes in operating assets and liabilities: The increase (decrease) during the reporting period in receivables from collaboration partners. Increase (Decrease) in Receivables from Collaboration Partners Receivables from collaborative and licensing arrangements Increase (Decrease) in Receivables for Milestone Payments Increase (Decrease) in Receivables for Milestone Payments Receivables from milestones and royalty assets The increase (decrease) during the reporting period in prepaid clinical and development services. Increase (Decrease) in Prepaid Clinical and Development Services Prepaid clinical and development services Increase (Decrease) in Prepaid Expenses, Other Other prepaid and current assets Amount of increase (decrease) in right-of-use assets for an operating lease. Increase (Decrease) in Right-of-use Assets Right-of-use lease assets Increase (Decrease) in Other Operating Assets Other assets Increase (Decrease) in Accounts Payable Accounts payable Increase (Decrease) in Accrued Liabilities Accrued personnel-related expenses, accrued clinical and development expenses, and other accrued liabilities Increase (Decrease) in Operating Lease Liability Operating lease liabilities Period Increase (Decrease), Unrecognized Tax Benefits Period Increase (Decrease), Unrecognized Tax Benefits Unrecognized tax benefits Increase (Decrease) in Other Noncurrent Liabilities Other long-term liabilities Cash Provided by (Used in) Operating Activity, Including Discontinued Operation Net cash provided by operating activities Cash Provided by (Used in) Investing Activity, Continuing Operation [Abstract] Investing activities Payments to Acquire Debt Securities, Available-for-Sale Purchases of marketable securities Proceeds from Sale and Maturity of Debt Securities, Available-for-Sale Maturities of marketable securities Cash Provided by (Used in) Investing Activity, Including Discontinued Operation Net cash provided by investing activities Cash Provided by (Used in) Financing Activity, Continuing Operation [Abstract] Financing activities Proceeds from Issuance of Common Stock Proceeds from the sale of ordinary shares Proceeds from Stock Options Exercised Proceeds from option exercises Payment, Tax Withholding, Share-Based Payment Arrangement Repurchase of shares to satisfy tax withholding Cash Provided by (Used in) Financing Activity, Including Discontinued Operation Net cash used in financing activities Cash, Cash Equivalent, Restricted Cash, and Restricted Cash Equivalent, Period Increase (Decrease), Including Exchange Rate Effect and Discontinued Operation Net increase in cash, cash equivalents, and restricted cash Cash, Cash Equivalent, Restricted Cash, and Restricted Cash Equivalent, Continuing Operation Cash, cash equivalents, and restricted cash at end of period Cash, cash equivalents, and restricted cash at beginning of period Total cash, cash equivalents, and restricted cash Supplemental Cash Flow Information [Abstract] Supplemental disclosure of cash flow information Income Taxes Paid, Net Cash (received) paid for income taxes, net Organization, Consolidation and Presentation of Financial Statements [Abstract] Organization, Consolidation and Presentation of Financial Statements Disclosure and Significant Accounting Policies [Text Block] Organization and Summary of Significant Accounting Policies Earnings Per Share [Abstract] Earnings Per Share [Text Block] Net Loss per Share Revenue from Contract with Customer [Abstract] Revenue from Contract with Customer [Text Block] Revenue Segment Reporting [Abstract] Segment Reporting Disclosure [Text Block] Segment Information Cash and Cash Equivalents [Abstract] Cash and Cash Equivalents Disclosure [Text Block] Cash, Cash Equivalents, and Restricted Cash Fair Value Disclosures [Abstract] Fair Value Disclosures [Text Block] Investments and Fair Value Measurements Leases [Abstract] Lessee, Operating Leases [Text Block] Subleases Share-Based Payment Arrangement [Abstract] Share-Based Payment Arrangement [Text Block] Share-Based Compensation Income Tax Disclosure [Abstract] Income Tax Disclosure [Text Block] Income Taxes Restructuring and Related Activities [Abstract] Restructuring and Related Activities Disclosure [Text Block] Organizational Restructuring Commitments and Contingencies Disclosure [Abstract] Legal Matters and Contingencies [Text Block] Commitments and Contingencies Basis of Accounting, Policy [Policy Text Block] Basis of Presentation Use of Estimates, Policy [Policy Text Block] Use of Estimates Disclosure of accounting policy for liquidity and capital resources. Liquidity and Capital Resources [Policy Text Block] Liquidity and Capital Resources Disclosure of accounting policy for significant accounting policies. Significant Accounting Policies [Policy Text Block] Significant Accounting Policies Disclosure of accounting policy for future royalty payment contingency. Future Royalty Payment Contingency [Policy Text Block] Future Royalty Payment Contingency New Accounting Pronouncements, Policy [Policy Text Block] Recently Issued Accounting Pronouncements Not Yet Adopted Schedule of Earnings Per Share, Basic and Diluted [Table Text Block] Schedule of basic and diluted net income (loss) per share Disaggregation of Revenue [Table Text Block] Schedule of amounts were recognized within revenue Tabular disclosure of implied share of total net sales in a collaborative arrangement. Collaborative Arrangement, Implied Share of Net Sales [Table Text Block] Schedule of implied share of total net sales Schedule of Segment Reporting Information, by Segment [Table Text Block] Summary of significant segment expenses Tabular disclosure of cash, cash equivalents and restricted cash as to withdrawal or usage. Schedule of Cash, Cash Equivalents and Restricted Cash [Table Text Block] Schedule of reconciliation of cash, cash equivalents, and restricted cash Schedule of Available-for-Sale Securities Reconciliation [Table Text Block] Summary of available-for-sale securities Debt Securities, Available-for-Sale, Unrealized Loss Position, Fair Value [Table Text Block] Schedule of available-for-sale debt securities with unrealized losses Fair Value, Assets Measured on Recurring Basis, Unobservable Input Reconciliation [Table Text Block] Schedule of changes to the contract derivative Lessee, Lease, Description [Table] Lessee, Lease, Description [Line Items] Lease, Cost [Table Text Block] Schedule of operating leases Schedule of Share-Based Compensation Arrangements by Share-Based Payment Award [Table] Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items] Share-Based Compensation Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Table Text Block] Schedule of share-based compensation expense included in the condensed consolidated statements of operations Share-Based Payment Arrangement, Option, Activity [Table Text Block] Summary of option activity Share-Based Payment Arrangement, Restricted Stock Unit, Activity [Table Text Block] Schedule of RSU activity Restructuring and Related Costs [Table Text Block] Schedule of elected information relating to accrued restructuring expenses Accounting Standards Update and Change in Accounting Principle [Table] Accounting Standards Update [Axis] Accounting Standards Update [Domain] Accounting Standards Update 2024-03 [Member] Accounting Standards Update 2024-03 New Accounting Pronouncements or Change in Accounting Principle [Line Items] Recently Issued Accounting Pronouncements Change in Accounting Principle, Accounting Standards Update, Adopted [true false] Change in Accounting Principle, Accounting Standards Update, Adopted Net Income (Loss) Available to Common Stockholders, Diluted [Abstract] Numerator: Net Income (Loss) Available to Common Stockholders, Basic Net loss available to common stockholders, basic Net Income (Loss) Available to Common Stockholders, Diluted Net loss available to common stockholders, diluted Weighted Average Number of Shares Outstanding Reconciliation [Abstract] Denominator: Collaborative Arrangement and Arrangement Other than Collaborative [Table] Collaborative Arrangement and Arrangement Other than Collaborative [Axis] Collaborative Arrangement and Arrangement Other than Collaborative [Domain] Collaborative Arrangement [Member] Collaborative Arrangement Collaborative Arrangement, Transaction with Party to Collaborative Arrangement [Member] Collaborative Arrangement, Transaction with Party to Collaborative Arrangement Counterparty Name [Axis] Counterparty Name [Domain] Viatris [Member] Viatris [Member] Viatris Geographical [Axis] Geographical [Domain] UNITED STATES United States European Union [Member] European Union Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] Collaborative Arrangement Collaborative Arrangement, Profit and Loss, Sharing Arrangement, Percentage, Counterparty Share Collaborative Arrangement, Profit and Loss, Sharing Arrangement, Percentage, Counterparty Share Collaborative arrangement, profit and loss, sharing arrangement, percentage, counterparty share (as a percent) Collaborative Arrangement, Profit and Loss, Sharing Arrangement, Percentage, Entity Share Collaborative Arrangement, Profit and Loss, Sharing Arrangement, Percentage, Entity Share Collaborative arrangement, profit and loss, sharing arrangement, percentage, entity share (as a percent) Collaborative Arrangement, Royalty, Tiered Royalties Receivable, Low End of Range Collaborative Arrangement, Royalty, Tiered Royalties Receivable, Low End of Range Collaborative arrangement, royalty, tiered royalties receivable, low end of range (as a percent) Collaborative Arrangement, Royalty, Tiered Royalties Receivable, High End of Range Collaborative Arrangement, Royalty, Tiered Royalties Receivable, High End of Range Collaborative arrangement, royalty, tiered royalties receivable, high end of range (as a percent) Collaborative Arrangement, Milestones, Global Sales and Regulatory Milestone, Receivable, Maximum Potential Collaborative Arrangement, Milestones, Global Sales and Regulatory Milestone, Receivable, Maximum Potential Collaborative arrangement, milestones, global sales and regulatory milestone, receivable, maximum potential Collaborative Arrangement, Milestones, Global Sales and Regulatory Milestone, Receivable, Maximum Potential, Monotherapy Collaborative Arrangement, Milestones, Global Sales and Regulatory Milestone, Receivable, Maximum Potential, Monotherapy Collaborative arrangement, milestones, global sales and regulatory milestone, receivable, maximum potential, monotherapy Collaborative Arrangement, Milestones, Global Sales and Regulatory Milestone, Receivable, Maximum Potential, Future Potential Combination Products Collaborative Arrangement, Milestones, Global Sales and Regulatory Milestone, Receivable, Maximum Potential, Future Potential Combination Products Collaborative arrangement, milestones, global sales and regulatory milestone, receivable, maximum potential, future potential combination products Collaborative Arrangement, Milestones, Sales and Regulatory Milestones, Receivable, Maximum Potential Collaborative Arrangement, Milestones, Sales and Regulatory Milestones, Receivable, Maximum Potential Collaborative arrangement, milestones, sales and regulatory milestones, receivable, maximum potential Collaborative Arrangement, Milestones, Sales and Regulatory Milestones, Receivable, Maximum Potential, Monotherapy Collaborative Arrangement, Milestones, Sales and Regulatory Milestones, Receivable, Maximum Potential, Monotherapy Collaborative arrangement, milestones, sales and regulatory milestones, receivable, maximum potential, monotherapy Collaborative Arrangement, Milestones, Sales and Regulatory Milestones, Receivable, Maximum Potential, Future Potential Combination Products Collaborative Arrangement, Milestones, Sales and Regulatory Milestones, Receivable, Maximum Potential, Future Potential Combination Products Collaborative arrangement, milestones, sales and regulatory milestones, receivable, maximum potential, future potential combination products Collaborative Arrangement, Milestones, Sales and Regulatory Milestones, Receivable, Maximum Potential, Monotherapy, Sales Milestones Collaborative Arrangement, Milestones, Sales and Regulatory Milestones, Receivable, Maximum Potential, Monotherapy, Sales Milestones Collaborative arrangement, milestones, sales and regulatory milestones, receivable, maximum potential, monotherapy, sales milestones Collaborative Arrangement, Milestones, Sales and Regulatory Milestones, Receivable, Maximum Potential, Monotherapy, Regulatory Approval Collaborative Arrangement, Milestones, Sales and Regulatory Milestones, Receivable, Maximum Potential, Monotherapy, Regulatory Approval Collaborative arrangement, milestones, sales and regulatory milestones, receivable, maximum potential, monotherapy, regulatory approval Product and Service [Axis] Product and Service [Domain] Licensing and Milestone [Member] Licensing and Milestone [Member] Licensing and Milestone License [Member] Licensing Milestone [Member] Milestone [Member] Milestone Collaborative Arrangement, Milestones, Sales and Regulatory Milestones, Achieved, Net Sales in Period, Domestic Collaborative Arrangement, Milestones, Sales and Regulatory Milestones, Achieved, Net Sales in Period, Domestic Collaborative arrangement, milestones, sales and regulatory milestones, achieved, net sales in period, domestic Disaggregation of Revenue [Table] Disaggregation of Revenue [Line Items] Legal Entity [Axis] All Entities [Member] YUPELRI Monotherapy [Member] YUPELRI Monotherapy [Member] YUPELRI Monotherapy Theravance Biopharma, Inc. [Member] Theravance Biopharma, Inc [Member] Theravance Biopharma, Inc. Revenues Revenues Segment Reporting, Disclosure of Entity's Reportable Segments [Abstract] Segment Reporting, Disclosure of Entity's Reportable Segments Number of Reportable Segments Number of reportable segments Segment Reporting, CODM, Individual Title and Position or Group Name [Extensible Enumeration] Segment Reporting, CODM, Individual Title and Position or Group Name Schedule of Segment Reporting Information, by Segment [Table] Segments [Axis] Segments [Domain] Single Reportable Segment [Member] Single Reportable Segment [Member] Single Reportable Segment Segment Reporting Information [Line Items] Segment Information Research and development expense during the period related to salary and wages. Research and Development Expense, Salary and Wages Employee-related (Research and development) Research and development expense during the period related to external party. Research and Development Expense, External Related Expense External-related (Research and development) Research and development expense during the period related to facilities, depreciation and other allocated expenses. Research and Development Expense, Facilities, Depreciation and Other Allocated Expenses Facilities and other allocated expenses (Research and development) Other General and Administrative Expense Supporting general and administration functions Selling and Marketing Expense Sales and marketing, and medical affairs Costs associated with normal operations except for the portion of these expenses which can be clearly related to production and included in cost of sales or services. Includes selling, general and administrative expense excluding any non recurring costs. Recurring Operating Expenses Total recurring operating expenses Cash, Cash Equivalent, Restricted Cash, and Restricted Cash Equivalent, Continuing Operation [Abstract] Cash, Cash Equivalents, and Restricted Cash Restricted Cash Restricted cash Debt Securities, Available-for-Sale [Table] Financial Instrument [Axis] Financial Instruments [Domain] US Treasury and Government [Member] US Treasury and Government Corporate Note Securities [Member] Corporate Note Securities Commercial Paper [Member] Commercial Paper Debt Securities, Available-for-Sale [Line Items] Debt Securities, Available-for-Sale, Fair Value to Amortized Cost, after Allowance for Credit Loss [Abstract] Debt Securities, Available-for-Sale, Fair Value to Amortized Cost, after Allowance for Credit Loss Debt Securities, Available-for-Sale, Amortized Cost, after Allowance for Credit Loss Amortized cost, available-for-sale securities Amortized cost Debt Securities, Available-for-Sale, Accumulated Gross Unrealized Gain, before Tax Gross unrealized gains Debt Securities, Available-for-Sale, Accumulated Gross Unrealized Loss, before Tax Gross unrealized losses Debt Securities, Available-for-Sale Estimated fair value Estimated fair value, available-for-sale securities Fair Value by Fair Value Hierarchy Level, Extensible Enumeration [Abstract] Fair Value by Fair Value Hierarchy Level, Extensible Enumeration Debt Securities, Available-for-Sale, Fair Value by Fair Value Hierarchy Level [Extensible Enumeration] Debt Securities, Available-for-Sale, Fair Value by Fair Value Hierarchy Level Money Market Funds, at Carrying Value Money market funds Debt Securities, Available-for-Sale, and Money Market Funds, Amortized Cost Debt Securities, Available-for-Sale, and Money Market Funds, Amortized Cost Amortized cost, total Debt Securities, Available-for-Sale and Money Market Funds Debt Securities, Available-for-Sale and Money Market Funds Estimated fair value, total Statistical Measurement [Axis] Statistical Measurement [Domain] Maximum [Member] Maximum Weighted Average [Member] Weighted Average Debt Securities, Available-for-Sale [Abstract] Debt Securities, Available-for-Sale Debt Securities, Available-for-Sale, Term Debt securities, available-for-sale, term Fair Value, Net Asset (Liability) [Abstract] Assets, Fair Value Disclosure [Abstract] Assets, Fair Value Disclosure Fair Value, Assets, Level 1 to Level 2 Transfer, Amount Fair Value, Assets, Level 1 to Level 2 Transfer, Amount Fair value of assets transferred from Level 1 to Level 2 Fair Value, Assets, Level 2 to Level 1 Transfer, Amount Fair Value, Assets, Level 2 to Level 1 Transfer, Amount Fair value of assets transferred from Level 2 to Level 1 Debt Securities, Available-for-Sale, Unrealized Loss Position, Fair Value [Table] Debt Securities, Available-for-Sale, Unrealized Loss Position [Line Items] Debt Securities, Available-for-Sale, Unrealized Loss Position [Abstract] Debt Securities, Available-for-Sale, Unrealized Loss Position Debt Securities, Available-for-Sale, Continuous Unrealized Loss Position, Less than 12 Months Estimated fair value, less than 12 months Debt Securities, Available-for-Sale, Unrealized Loss Position Estimated fair value, total Debt Securities, Available-for-Sale, Unrealized Loss Position, Accumulated Loss [Abstract] Debt Securities, Available-for-Sale, Unrealized Loss Position, Accumulated Loss Debt Securities, Available-for-Sale, Continuous Unrealized Loss Position, Less than 12 Months, Accumulated Loss Gross unrealized losses, less than 12 months Debt Securities, Available-for-Sale, Unrealized Loss Position, Accumulated Loss Gross unrealized losses, total Debt Securities, Available-for-Sale, Amortized Cost, after Allowance for Credit Loss [Abstract] Debt Securities, Available-for-Sale, Amortized Cost, after Allowance for Credit Loss Debt Securities, Available-for-Sale, Allowance for Credit Loss Debt securities, available-for-sale, allowance for credit loss Debt Securities, Available-for-Sale, Continuous Unrealized Loss Position, Number of Positions [Abstract] Debt Securities, Available-for-Sale, Continuous Unrealized Loss Position, Number of Positions Debt Securities, Available-for-Sale, Unrealized Loss Position, Number of Positions Debt securities, available-for-sale, unrealized loss position, number of positions Proceeds from Sale and Maturity of Debt Securities, Available-for-Sale [Abstract] Proceeds from Sale and Maturity of Debt Securities, Available-for-Sale Proceeds from Sale of Debt Securities, Available-for-Sale Available-for-sale securities sold Collaborative Arrangement, Closing Consideration Payment Collaborative Arrangement, Closing Consideration Payment Collaborative arrangement, closing consideration payment Collaborative Arrangement, Milestones, Regulatory Approval, Receivable Collaborative Arrangement, Milestones, Regulatory Approval, Receivable Collaborative arrangement, milestones, regulatory approval, receivable Fair Value, Assets Measured on Recurring Basis, Unobservable Input Reconciliation, Calculation [Roll Forward] Fair Value, Assets Measured on Recurring Basis, Unobservable Input Reconciliation, Calculation Fair Value, Measurement with Unobservable Inputs Reconciliation, Recurring Basis, Asset Value Contract derivative, ending balance Contract derivative, beginning balance Fair Value, Measurement with Unobservable Inputs Reconciliation, Recurring Basis, Asset, Gain (Loss) Included in Earnings Unrealized gain Fair Value, Asset, Recurring Basis, Unobservable Input Reconciliation, Gain (Loss), Statement of Income or Comprehensive Income [Extensible Enumeration] Fair Value, Asset, Recurring Basis, Unobservable Input Reconciliation, Gain (Loss), Statement of Income or Comprehensive Income Fair Value Measurement Inputs and Valuation Techniques [Abstract] Fair Value Measurement Inputs and Valuation Techniques Derivative Asset, Measurement Input Derivative asset, measurement input Derivative Asset, Measurement Input [Extensible Enumeration] Derivative Asset, Measurement Input Derivative Asset [Abstract] Derivative Asset Derivative Asset Contract derivative Derivative Asset, Statement of Financial Position [Extensible Enumeration] Derivative Asset, Statement of Financial Position Long-Lived Tangible Asset [Axis] Long-Lived Tangible Asset [Domain] Land and Building [Member] Building [Member] South San Francisco Lease [Member] South San Francisco Lease [Member] South San Francisco Lease Lessee, Operating Lease, Description [Abstract] Lessee, Operating Lease, Description Area of Real Estate Property Area of real estate property Lessee, Operating Sublease, Description [Abstract] Lessee, Operating Sublease, Description Lessee, Operating Sublease, Area Lessee, Operating Sublease, Area Lessee, operating sublease, area Lessee, Operating Sublease, Subtenants, Number Lessee, Operating Sublease, Subtenants, Number Lessee, operating sublease, subtenants, number Lessee Disclosure [Abstract] Income and Expenses, Lessee [Abstract] Sublease Income Sublease Income Operating sublease income Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Table] Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Line Items] Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Abstract] Share-based compensation expense Restructuring Plan [Axis] Restructuring Plan [Domain] Organizational Restructure, 2026 [Member] Organizational Restructure, 2026 [Member] Organizational Restructuring, 2026 Share-Based Payment Arrangement, Plan Modification, Incremental Cost Share-based payment arrangement, plan modification, incremental cost Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding [Roll Forward] Number of Shares Subject to Outstanding Options Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Number Ending balance, outstanding (in shares) Beginning balance, outstanding (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Forfeitures in Period Forfeited (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Expirations in Period Expired (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Exercise Price [Abstract] Weighted-Average Exercise Price of Outstanding Options Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Exercise Price Ending balance, outstanding (in dollars per share) Beginning balance, outstanding (in dollars per share) Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Exercises in Period, Weighted Average Exercise Price Exercised (in dollars per share) Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Forfeitures in Period, Weighted Average Exercise Price Forfeited (in dollars per share) Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Expirations in Period, Weighted Average Exercise Price Expired (in dollars per share) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Additional Disclosures [Abstract] Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Additional Disclosures Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Weighted Average Remaining Contractual Term Weighted-average remaining contractual term, exercisable Award Type [Axis] Award Type [Domain] Restricted Stock Units (RSUs) [Member] Restricted Stock Units (RSUs) Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Number of Shares [Roll Forward] Number of shares subject to outstanding RSUs Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Number Ending balance, outstanding (in shares) Beginning balance, outstanding (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Grants in Period Granted (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Vested in Period Released (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Forfeited in Period Forfeited (in shares) Income Tax Expense (Benefit), Continuing Operations [Abstract] Income Tax Expense (Benefit), Continuing Operations Deferred Tax Liability Not Recognized, Undistributed Earnings of Foreign Subsidiaries [Abstract] Deferred Tax Liability Not Recognized, Undistributed Earnings of Foreign Subsidiaries Deferred Tax Liability Not Recognized, Amount of Unrecognized Deferred Tax Liability, Undistributed Earnings of Foreign Subsidiaries Provision for income taxes on undistributed earnings of foreign subsidiaries Restructuring Cost [Table] Minimum [Member] Minimum Restructuring Cost and Reserve [Line Items] Restructuring and Related Cost [Abstract] Restructuring and Related Cost, Positions Eliminated [Abstract] Restructuring and Related Cost, Positions Eliminated Entity Number of Employees Entity number of employees Restructuring and Related Cost, Expected Number of Positions Eliminated, Percent Restructuring and Related Cost, Expected Number of Positions Eliminated, Percent Restructuring and related cost, expected number of positions eliminated, percent (as a percent) Restructuring and Related Cost, Expected Cost [Abstract] Restructuring and Related Cost, Expected Cost Restructuring and Related Cost, Expected Cost Restructuring and related cost, expected cost, cash-related expenses Restructuring and Related Cost, Expected Cost, Noncash Related Expenses Restructuring and Related Cost, Expected Cost, Noncash Related Expenses Restructuring and related cost, expected cost, non-cash related expenses General and Administrative Expense [Member] General and Administrative Expense Restructuring Reserve Disclosures [Abstract] Restructuring Reserve [Roll Forward] Restructuring Reserve Restructuring Reserve Balance at end of period Balance at beginning of period Loss Contingencies [Table] Loss Contingencies [Line Items] Loss Contingency Accrual, Disclosures [Abstract] Loss Contingency Accrual, Disclosures Loss Contingency Accrual Loss contingency accrual Litigation Case [Axis] Litigation Case [Domain] Patent Infringement, Generic Companies [Member] Patent Infringement, Generic Companies [Member] Patent Infringement, Generic Companies Loss Contingency, Information about Litigation Matters [Abstract] Loss Contingency, Information about Litigation Matters Number of patents listed in orange book. Number of Patents Listed in Orange Book Number of patents listed in orange book