75000 - Document - Document and Entity Information
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75010 - Statement - Condensed Consolidated Balance Sheets (unaudited)
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75020 - Statement - Condensed Consolidated Balance Sheets (Parenthetical) (unaudited)
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75030 - Statement - Condensed Consolidated Statements of Operations and Comprehensive Loss (unaudited)
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75040 - Statement - Condensed Consolidated Statements of Operations and Comprehensive Loss (Parenthetical)
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75050 - Statement - Condensed Consolidated Statements of Stockholders' Equity (Unaudited)
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75060 - Statement - Condensed Consolidated Statements of Stockholders' Equity (Unaudited) (Parenthetical)
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75070 - Statement - Condensed Consolidated Statements of Cash Flows (Unaudited)
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995455 - Disclosure - Nature of Operations and Basis of Presentation
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995465 - Disclosure - Summary of Significant Accounting Policies
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995475 - Disclosure - Asset Acquisition and Private Placement with a Related Party
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995495 - Disclosure - Fair Value Measurements
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995505 - Disclosure - Accrued Expenses and Other Current Liabilities
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995515 - Disclosure - Redeemable Convertible Preferred Stock
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995525 - Disclosure - Redeemable Convertible Preferred Stock Tranche Liability
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995535 - Disclosure - Commitments and Contingencies
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995545 - Disclosure - Related Party Transactions
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995555 - Disclosure - Stock-Based Compensation
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995565 - Disclosure - Net Loss Per Share
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995575 - Disclosure - Segments
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995585 - Disclosure - Restructuring Costs
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995595 - Disclosure - Subsequent Events
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995605 - Disclosure - License Agreements
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995615 - Disclosure - Summary of Significant Accounting Policies (Policies)
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995625 - Disclosure - Summary of Significant Accounting Policies (Tables)
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995635 - Disclosure - Asset Acquisition and Private Placement with a Related Party (Tables)
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995655 - Disclosure - Fair Value Measurements (Tables)
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995665 - Disclosure - Accrued Expenses and Other Current Liabilities (Tables)
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995675 - Disclosure - Redeemable Convertible Preferred Stock (Tables)
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995685 - Disclosure - Redeemable Convertible Preferred Stock Tranche Liability (Tables)
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995695 - Disclosure - Commitments and Contingencies (Tables)
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995705 - Disclosure - Stock-Based Compensation (Tables)
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995715 - Disclosure - Net Loss Per Share (Tables)
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995725 - Disclosure - Segments (Tables)
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995735 - Disclosure - Restructuring Costs (Tables)
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995745 - Disclosure - Nature of Operations and Basis of Presentation - Additional Information (Details)
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995755 - Disclosure - Summary of Significant Accounting Policies - Schedule of Fair Value Measurements (Details)
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995765 - Disclosure - Asset Acquisition and Private Placement with a Related Party (Additional Information) (Details)
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995775 - Disclosure - Asset Acquisition and Private Placement with a Related Party - The Fair Value of the Total Consideration Comprised of the Components (Details)
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995785 - Disclosure - Asset Acquisition and Private Placement with a Related Party - Schedule of Assets Acquired And Liabilities Assumed In Athenen Acquisition (Details)
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995795 - Disclosure - Fair Value Measurements - Schedule of Fair Value of Assets and Liabilities Measured on Recurring Basis (Details)
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995805 - Disclosure - Fair Value Measurements (Additional Information) (Details)
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995815 - Disclosure - Accrued Expenses and Other Current Liabilities - Summary of Accrued expenses and other current liabilities (Details)
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995825 - Disclosure - Accrued Expenses and Other Current Liabilities - Summary of Accrued expenses and other current liabilities (Details) 2
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995855 - Disclosure - Investments - Investments in a continual unrealized loss position (Details)
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995865 - Disclosure - License Agreements (Additional Information) (Details)
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995875 - Disclosure - Investments - Additional Information (Details)
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995885 - Disclosure - Certain Balance Sheet Accounts - Summary of Prepaid Expenses and Other Current Assets (Details)
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995895 - Disclosure - Certain Balance Sheet Accounts - Summary of Other Long-Term Assets (Details)
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995905 - Disclosure - Certain Balance Sheet Accounts - Summary of Other Long-Term Assets (Details) 2
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995915 - Disclosure - Redeemable Convertible Preferred Stock - Schedule of Convertible Preferred Stock (Details)
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995925 - Disclosure - Redeemable Convertible Preferred Stock - Additional Information (Details)
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995935 - Disclosure - Redeemable Convertible Preferred Stock Tranche Liability - Additional Information - (Details)
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995945 - Disclosure - Redeemable Convertible Preferred Stock Tranche Liability - Schedule of Valuation of The Redeemable Convertible Preferred Stock Tranche Liability (Details)
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995955 - Disclosure - Redeemable Convertible Preferred Stock Tranche Liability - Schedule of The Rollforward Redeemable Convertible Preferred Stock Tranche Liability (Details)
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995965 - Disclosure - Commitments and Contingencies - Future Minimum Lease Payments Under Non-Cancelable Operating Leases (Details)
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995975 - Disclosure - Commitments and Contingencies - Additional Information (Details)
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995985 - Disclosure - Related Party Transactions (Additional Information) (Details)
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995995 - Disclosure - Stock-Based Compensation - Additional Information (Details)
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996005 - Disclosure - Stock-Based Compensation - Summary of Assumptions Used in Black-Scholes Model (Details)
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996015 - Disclosure - Stock-Based Compensation - Summary of Stock Option Activities (Details)
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996025 - Disclosure - Stock-Based Compensation - Summary of Stock Option Activities (Parenthetical) (Details)
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996035 - Disclosure - Stock-Based Compensation - Summary of Restricted Stock Awards (Details)
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996045 - Disclosure - Stock-Based Compensation - Summary of Share-based Compensation Expense (Details)
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996055 - Disclosure - Net Loss Per Share - Additional Information (Details)
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996065 - Disclosure - Net Loss Per Share - Basic and Diluted Net Loss Per Share (Details)
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996075 - Disclosure - Net Loss Per Share - Schedule of Antidilutive Securities Excluded from Computation of Net Loss Per Share Attributable to Common Stockholders (Details)
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996085 - Disclosure - Segments - Schedule of Forth Disaggregated Research and Development Expenses (Details)
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996095 - Disclosure - Segments (Additional Information) (Details)
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996105 - Disclosure - Restructuring Costs (Additional Information) (Details)
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996115 - Disclosure - Restructuring Costs - Schedule of restructuring liability (Details)
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996125 - Disclosure - Restructuring Costs - Schedule of restructuring costs in statement of operations (Details)
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996135 - Disclosure - Subsequent Events (Additional Information) (Details)
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Underwritten public offering.
Underwritten Public Offering [Member]
Underwritten Public Offering
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Vested in Period, Weighted Average Grant Date Fair Value
Vested, weighted average grant date fair value per share
Percentage of temporary equity shares outstanding.
Percentage Of Temporary Equity Shares Outstanding
Percentage of outstanding shares
Restructuring Liability, Ending Balance
Restructuring Liability, Beginning Balance
Restructuring Reserve
Restructuring Reserve, Total
Pre Funded Warrant [Member]
Pre Funded Warrant [Member]
Pre Funded Warrant [Member]
Entity Incorporation, State or Country Code
Entity Incorporation, State or Country Code
Statement of Financial Position Location, Balance [Domain]
Increase (Decrease) in Accounts Payable, Total
Increase (Decrease) in Accounts Payable
Accounts payable
Cash Flow, Noncash Investing and Financing Activities Disclosure [Abstract]
Supplemental disclosure of non-cash investing and financing activities:
Financing Receivable Portfolio Segment [Axis]
Plan Name [Axis]
Plan Name
Entity Current Reporting Status
Entity Current Reporting Status
US Government Agencies Debt Securities [Member]
US Government Agencies Debt Securities [Member]
Operating Expenses [Abstract]
Operating expenses:
Development Regulatory Commercial and Sales Milestones Member]
Development Regulatory Commercial and Sales Milestones Member]
Fair Value, Inputs, Level 2 [Member]
Level 2 [Member]
Level 2
Commitments and Contingencies Disclosure [Text Block]
Commitments and Contingencies
Common Stock, Shares Authorized
Common stock, shares authorized
Redeemable convertible preferred stock tranche liability.
Redeemable Convertible Preferred Stock Tranche Liability Disclosure [Text Block]
Redeemable Convertible Preferred Stock Tranche Liability
Sera Services Agreement [Member]
Sera Services Agreement [Member]
Sera Services Agreement [Member]
Temporary equity, par value
Temporary Equity, Par or Stated Value Per Share
Temporary Equity, par value
Option Indexed to Issuer's Equity, Type
Option Indexed to Issuer's Equity, Type [Axis]
Product and Service [Axis]
Fair Value by Liability Class [Domain]
Fair Value by Liability Class
Research And Development Asset Acquired In Process
Research and development asset acquired in process
In-process research and development, related party
Acquired in-process research and development, related party
Document Fiscal Period Focus
Document Fiscal Period Focus
Business Combination Consideration Transferred Settlement Of Pre-Existing Loan
Settlement of pre-existing loan
Amount of a pre-existing loan that was settled as part of a business combination.
Entity Shell Company
Entity Shell Company
Temporary Equity, Shares Outstanding
Ending balance (in shares)
Beginning balance (in shares)
Temporary Equity, Shares Outstanding
Other Accrued Liabilities, Current
Other accrued expenses and current liabilities
Direct Transaction Costs
Direct Transaction Costs
Direct transaction costs
Cash and Cash Equivalents, at Carrying Value, Total
Cash and Cash Equivalents, at Carrying Value, Beginning Balance
Cash and Cash Equivalents, at Carrying Value, Ending Balance
Cash and Cash Equivalent
Cash and cash equivalents
Tabular disclosure for rollforward of redeemable convertable preferred stock tranche liability.
Schedule Of The Rollforward Redeemable Convertible Preferred Stock Tranche Liability Table [Text Block]
Schedule of the Rollforward Redeemable Convertible Preferred Stock Tranche Liability
Subsidiary Sale Of Stock [Line Items]
Subsidiary, Sale of Stock [Line Items]
Common Stock, Shares, Issued, Total
Common Stock, Shares, Issued
Common stock, shares issued
Common stock
Statement [Table]
Statement [Table]
Proceeds from issuance of redeemable convertible preferred stock and related tranche rights, net of issuance costs
Proceeds from issuance of redeemable convertible preferred stock, net of issuance costs
Proceeds from Issuance of Redeemable Convertible Preferred Stock
Schedule of restructuring liability [Table Textblock]
Schedule of restructuring liability
Schedule of restructuring liability
Right-of-Use Asset Obtained in Exchange for Operating Lease Liability
Operating lease liabilities arising from obtaining right-of-use assets
Interest Receivable
Accrued interest receivable
Investment interest receivable
Pre-Funded Warrant [Member]
Pre-Funded Warrant [Member]
Pre-Funded Warrant [Member]
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Grants in Period, Weighted Average Grant Date Fair Value
Options grants in period, weighted average grant date fair value
Fair value of share of common stock
Share-Based Compensation Arrangement by Share-Based Payment Award, Purchase Price of Common Stock, Percent
Share based payment award, purchase price of common stock, percent
Marketable Securities
Marketable Securities [Member]
Marketable Securities [Member]
Temporary Equity, Issue Price
temporary equity issue price
Temporary equity issue price.
Statement [Line Items]
Statement [Line Items]
Business Combination [Domain]
Other [Member]
Other Expense [Member]
Entity Filer Category
Entity Filer Category
Eliem [Member]
Eliem [Member]
Eliem [Member]
Liabilities and Equity
Total liabilities and stockholders' equity
Total liabilities assumed
Business Combination, Recognized Liability Assumed, Liability, Current
Business Combination, Recognized Identifiable Assets Acquired and Liabilities Assumed, Current Liabilities, Total
Gain Contingencies [Line Items]
Payments to Acquire Marketable Securities, Total
Payments to Acquire Marketable Securities
Purchase of marketable securities
Purchases of marketable securities
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Weighted Average Exercise Price
Weighted average exercise price, options exercisable
Restructuring Type [Axis]
Summary of Investment Holdings [Line Items]
Share based compensation arrangement by sharebased payment award contribution percent maximum
Share Based Compensation Arrangement By Sharebased Payment Award Contribution Percent Maximum
The maximum amount an employee is allowed to contribute for the purchase of common stock under a share based compensation plan, as a percentage of their earnings
Fair Value, Liabilities Measured on Recurring Basis [Table Text Block]
Schedule of Fair Value Measurements
Prepaid Expenses and Other Current Assets [Member]
Prepaid Expenses and Other Current Assets [Member]
Percentage of share capital acquired
Business Combination, Voting Equity Interest Acquired, Percentage
Restructuring and Related Costs [Table Text Block]
Schedule of restructuring costs
Deferred Revenue [Domain]
Number of shares of common Stock outstanding percentage
Number of Shares of Common Stock Outstanding Percentage
Cash equivalents
Cash and Cash Equivalents, Fair Value Disclosure
Subsequent Event [Line Items]
Distribution Agreement [Member]
Distribution Agreement [Member]
Investment Income, Interest
Interest income
First Day of Offering Period [Member]
First Day of Offering Period [Member]
Milestone Payment, Amount Reduced
Milestone Payment, Amount Reduced
The amount of reduction in milestone payments due upon performing specified services.
Debt Securities, Available-for-Sale, Noncurrent
Estimated Fair Value, Long-term marketable securities
Contractual maturity
Debt Securities, Available-for-Sale, Term
Additional Paid in Capital, Common Stock, Ending Balance
Additional Paid in Capital, Common Stock, Beginning Balance
Additional Paid in Capital, Common Stock
Additional paid-in capital
Related Party [Member]
Related Party [Member]
Significant Accounting Policies [Text Block]
Summary of Significant Accounting Policies
Option Granted
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Grants in Period, Gross
Number of options granted
Long Term Marketable Securities [Member]
Long Term Marketable Securities [Member]
Long Term Marketable Securities [Member]
Schedule of Basic and Diluted Net Loss Per Share
Schedule of Earnings Per Share, Basic and Diluted [Table Text Block]
Budoprutug Service [Member]
Budoprutug Service [Member]
Budoprutug Service [Member]
Earnings Per Share, Basic
Earnings Per Share, Basic, Total
Net loss per share, Basic
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Number
Number of options outstanding, ending of period
Number of options outstanding, beginning of period
Schedule of Available-for-Sale Securities Reconciliation [Table Text Block]
Marketable securities consisted of available-for-sale securities
Business Combination, Recognized Asset Acquired, Asset, Current
Total assets acquired
Sales Milestones [Member]
Sales Milestones [Member]
Liabilities, Current
Total current liabilities
Adjustment to Reconcile Net Income to Cash Provided by (Used in) Operating Activity [Abstract]
Adjustments to reconcile net loss to net cash used in operating activities:
Other long term assets.
Other Long Term Assets
Other Assets
Consolidation Items [Domain]
Milestone Payments
Milestone Payments
The amount due from the Company upon achievement of specified milestones, as part of a license agreement.
Equity, Attributable to Parent [Abstract]
Stockholders' equity
Entity Small Business
Entity Small Business
Retained Earnings (Accumulated Deficit)
Accumulated deficit
Retained Earnings (Accumulated Deficit), Ending Balance
Retained Earnings (Accumulated Deficit), Beginning Balance
Retained Earnings (Accumulated Deficit), Total
Nature of Operations [Text Block]
Nature of Operations and Basis of Presentation
Subsidiary or Equity Method Investee, Sale of Stock, Type [Table]
Subsidiary Or Equity Method Investee Sale Of Stock By Subsidiary Or Equity Investee [Table]
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Forfeitures in Period
Number of options, forfeited
Options exercised
Sale of Stock, Price Per Share
Per share price
Sale of Stock, Price Per Share
Aggregate intrinsic value of options exercised
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercises in Period, Intrinsic Value
Remaining Loan Commitment Amount
Remaining Loan Commitment Amount
Remaining loan commitment amount
Share-Based Payment Arrangement [Text Block]
Stock-Based Compensation
Income tax.
Income Tax
Amount of income tax
Organization, Consolidation and Presentation of Financial Statements [Abstract]
Lease Contractual Term [Axis]
Leases [Abstract]
Lessee, Lease, Description [Line Items]
Amendment Flag
Amendment Flag
Product and Service [Domain]
Aggregate gross sales proceeds under sales agreement
Aggregate Gross Sales Proceeds Under Sales Agreement
Definition: The aggregate gross sales proceeds available under a sales agreement to sell shares of the Company's common stock.
Warrants issued for purchase of common stock
Class of Warrant or Right, Number of Securities Called by Warrants or Rights
Chief Executive Officer [Member]
Chief Executive Officer [Member]
Liabilities and Equity [Abstract]
Liabilities and Stockholders' Equity
Entity Address, Postal Zip Code
Entity Address, Postal Zip Code
Cash Provided by (Used in) Operating Activity, Including Discontinued Operation
Net cash used in operating activities
Increase (Decrease) in Operating Lease Liability
Operating lease liabilities
Increase decrease in operating lease liability
Recoverable research and development tax credits noncurrent.
Recoverable Research And Development Tax Credits Noncurrent
Recoverable research and development tax credits
Legacy Program Expenses [Member]
Legacy Program Expenses [Member]
Legacy Program Expenses [Member]
Segment Reporting Codm Profit Loss, Description
Segment Reporting, CODM, Profit (Loss) Measure, How Used, Description
Common Stock [Member]
Common Stock [Member]
Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Grants in Period, Weighted Average Exercise Price
Weighted average exercise price, options granted
Debt Securities, Available-for-Sale [Line Items]
Temporary equity automatic conversion sale of common stock price per share.
Temporary Equity Automatic Conversion Sale Of Common Stock Per Share
Temporary equity, automatic conversion, sale of common stock, price per share
Consultant
Consultant [Member]
Consultant [Member]
Entity Address, Address Line One
Entity Address, Address Line One
Prepaid research and development expenses.
Prepaid Research And Development Expenses
Prepaid research and development expenses
Summary of Stock Options Valuation Assumptions
Schedule of Share-Based Payment Award, Stock Options, Valuation Assumptions [Table Text Block]
Marketable Securities [Table]
Fair Value Hierarchy and NAV [Axis]
Fair Value Hierarchy and NAV
Earnings Per Share [Abstract]
Accrued External Research And Developments Expense
Carrying value as of the balance sheet date of obligations incurred through that date and payable for external research and development. Used to reflect the current portion of the liabilities (due within one year or within the normal operating cycle if longer).
Accrued external research and development expenses
Temporary Equity, Carrying Value
Ending balance
Beginning balance
Temporary Equity, Carrying Amount, Attributable to Parent
Redeemable convertible preferred stock, $0.0001 par value, 10000000 and 12,909,389 shares authorized, 7140157 shares issued and outstanding with aggregate liquidation preference of $0 and $49,891 at September 30, 2021 and December 31, 2020, respectively
Supplemental Cash Flow Information [Abstract]
Supplemental disclosure of cash flow information:
Foreign Currency
Foreign Currency Transactions and Translations Policy [Policy Text Block]
Statement of Financial Position Location, Balance [Axis]
Operating Lease, Right-of-Use Asset
Operating lease right-of-use assets
Class of Warrant or Right [Axis]
Document Type
Document Type
Preferred Stock, Per Share Amounts of Preferred Dividends in Arrears
Preferred dividend, per share
Total Restructuring Charges
Total Restructuring Charges
Total Restructuring Charges
Collaborative Arrangement and Arrangement Other than Collaborative [Axis]
Stock Issued During Period, Shares, Period Increase (Decrease)
Available Increase Shares
Collaborative Arrangement and Arrangement Other than Collaborative [Domain]
Entity Central Index Key
Entity Central Index Key
Present value adjustment for minimum lease commitments
Present value adjustment for minimum lease commitments
Present value adjustment
Derivatives used in Net Investment Hedge, Net of Tax, Beginning Balance
Derivatives used in Net Investment Hedge, Net of Tax, Ending Balance
Derivatives used in Net Investment Hedge, Net of Tax
Net of tax, Investment
Cash, Cash Equivalent, Restricted Cash, and Restricted Cash Equivalent, Period Increase (Decrease), Including Exchange Rate Effect and Discontinued Operation
Net change in cash and cash equivalents
Subsequent Event Type [Domain]
Subsequent Event Type
Antidilutive Securities Excluded from Computation of Earnings Per Share, Amount
Redeemable convertible preferred stock
Balance Sheet Related Disclosures [Abstract]
Common Stock, Par or Stated Value Per Share
Common stock, par value
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExpiresInPeriod
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExpiresInPeriod
Options expired
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Remaining Contractual Term
Weighted average remaining contractual terms (in years) outstanding
Debt Securities, Available-for-Sale
Debt Securities, Available-for-Sale, Total
Marketable securities
Amount of in-process research and development assets acquired
Amount of in-process research and development asset acquired in business combination and recognized at acquisition date
In-process research and development
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercises in Period
Number of options exercised
Issuance of common stock upon exercise of stock options, shares
Ownership [Domain]
Temporary Equity Discount Rate
Temporary equity discount rate.
Discount rate
Current Fiscal Year End Date
Current Fiscal Year End Date
Document Quarterly Report
Document Quarterly Report
Preferred Stock, Amount of Preferred Dividends in Arrears
Dividends preferred stock
Temporary equity, per share
Temporary equity value per share.
Temporary Equity Value Per Share
Entity Address, State or Province
Entity Address, State or Province
Number of shares, Unvested
Number of shares, Unvested
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Number
Summary of Purchase Consideration For The Acquisition Based On The Fair Value Of The Net Assets Acquired By The Company
Business Combination [Table Text Block]
Comprehensive loss
Comprehensive Income (Loss), Net of Tax, Attributable to Parent
Debt Securities, Available-for-Sale, Accumulated Gross Unrealized Gain, before Tax
Unrealized Gain
Common stock reserved for future issuance
Common Stock, Capital Shares Reserved for Future Issuance
Class of Warrant or Right [Domain]
CODM [Member]
Chief Operating Officer [Member]
Short-term marketable securities
Marketable Securities, Current, Total
Marketable Securities, Current
Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Table Text Block]
Summary of Share-based Compensation Expense
Research And License Agreement Upfront Payment Due
Research And License Agreement Upfront Payment Due
Research And License Agreement Upfront Payment Due
Stock Issued During Period, Value, Stock Options Exercised
Issuance of common stock upon exercise of stock options
Accounts Payable, Accrued Liabilities, and Other Liabilities Disclosure, Current [Text Block]
Accrued Expenses and Other Current Liabilities
Performance Shares [Member]
Workforce reduction number of employees
Workforce reduction number of employees
Workforce Reduction Number Of Employees
Proceeds from Sale and Maturity of Marketable Securities, Total
Proceeds from Sale and Maturity of Marketable Securities
Proceeds from maturities of marketable securities
Subsequent Event [Member]
Subsequent Event [Member]
Share-Based Compensation Arrangement by Share-Based Payment Award, Number of Additional Shares Authorized
Share based compensation arrangement by share based payment award
Other Assets, Noncurrent
Other long-term assets
Total other long-term assets
Total other long-term assets
Gain (Loss) on Contract Termination
Termination related expense
Debt Securities, Available-for-Sale, Current
Estimated FairValue, Short-term marketable securities
Deferred Revenue Arrangement Type [Axis]
Antidilutive Securities [Axis]
Antidilutive Securities
First Anniversary [Member]
First Anniversary Member
First Anniversary Member
Prepaid expenses and other current assets
Business Combination, Recognized Asset Acquired, Prepaid Expense and Other Asset, Current
Debt Securities, Available-for-Sale, Amortized Cost, Noncurrent
Amortized Cost, Long-term marketable securities
Share-Based Compensation Arrangement by Share-Based Payment Award, Award Vesting Rights, Percentage
Share-based payment award, award vesting rights, percentage
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Vested in Period, Fair Value
Fair value upon vested
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Outstanding, Aggregate Intrinsic Value
Aggregate intrinsic value options vested and expected to vest
Issuance of promissory loan in connection with asset acquisition
Issuance Of Promissory Loan In Connection With Assets Acquisition
The cash outflow associated with the issuance of a promissory loan in connection with an asset acquisition.
Share-Based Payment Arrangement, Cost by Plan [Table Text Block]
Summary of Share-based Compensation Expense
Related Party Transaction [Axis]
Accumulated Other Comprehensive Loss [Member]
AOCI Attributable to Parent [Member]
Unvested restricted stock awards member.
Unvested Restricted Stock Awards [Member]
Unvested Restricted Stock Awards
Acelyrin Asset Purchase Agreement [Member]
Acelyrin Asset Purchase Agreement [Member]
Cash and Cash Equivalents [Domain]
Summary of Total Consideration Comprised of Following
Asset Acquisition, Contingent Consideration [Table Text Block]
Business Combination, Consideration Transferred
Business Combination, Consideration Transferred, Total
Total consideration
Minimum [Member]
Minimum [Member]
Granted, weighted average grant date fair value
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Grants in Period, Weighted Average Grant Date Fair Value
Financial Instrument [Axis]
Acquisition Agreement [Member]
Acquisition Agreement
Acquisition Agreement [Member]
Assets, Current [Abstract]
Current assets:
Series A1 redeemable convertible preferred stock member.
Series A1 Redeemable Convertible Preferred Stock [Member]
Series A1 Redeemable Convertible Preferred Stock [Member]
Fair Value, Inputs, Level 3 [Member]
Level 3 [Member]
Level 3
Liabilities, Fair Value Disclosure [Abstract]
Liabilities:
Segment Reporting [Abstract]
Milestone Payments Due
The amount due as a result of achievement of specified milestones, as of the balance sheet date.
Schedule of Fair Value, Assets and Liabilities Measured on Recurring Basis
Schedule of Fair Value, Assets and Liabilities Measured on Recurring Basis [Table Text Block]
Business Combination [Policy Text Block]
Business Combination
Liabilities, Current [Abstract]
Current liabilities:
Short Term Marketable Securities [Member]
Short Term Marketable Securities [Member]
Short Term Marketable Securities [Member]
Restructuring and Related Activities Disclosure [Text Block]
Restructuring Costs
Simple interest
Debt Conversion, Original Debt, Interest Rate of Debt
Interest rate
Related Party Transactions [Abstract]
Shares, Outstanding
Ending balance, shares
Beginning balance, shares
Commitments and Contingencies
Commitments and contingencies (Note 6)
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Weighted Average Grant Date Fair Value
Unvested, weighted average grant date fair value per share, ending balance
Unvested, weighted average grant date fair value per share, beginning balance
Upfront Payment Paid
The amount of upfront payment paid during the period as part of a license agreement.
Upfront Payment Paid
General and Administrative Expense [Member]
General and Administrative Expense
Operating Lease, Liability
Total operating lease liabilities
Increase (Decrease) in Prepaid Expenses, Other
Prepaid expenses and other current assets
CLYM116 [Member]
CLYM116 [Member]
CLYM116 [Member]
Long-term marketable securities
Marketable Securities, Noncurrent
Effect of Exchange Rate on Cash, Cash Equivalents, Restricted Cash and Restricted Cash Equivalents, Including Disposal Group and Discontinued Operations, Total
Effect of Exchange Rate on Cash, Cash Equivalent, Restricted Cash, and Restricted Cash Equivalent, Including Discontinued Operation
Effect of exchange rate changes on cash and cash equivalents
Net loss
Net loss and comprehensive loss
Net loss and comprehensive loss
Net Income (Loss), Including Portion Attributable to Noncontrolling Interest
Lease Contractual Term [Domain]
Business Combination, Recognized Asset Acquired, Cash and Cash Equivalent
Cash and cash equivalents
Common stock issued in exchange for in-process research and development assets
The value of common stock issued in exchange for in-process research and development asset as part of an asset acquisition.
Issuance of common stock in exchange for in-process research and development
Weighted Average Number of Shares Outstanding, Basic
Weighted Average Number of Shares Outstanding, Basic, Total
Weighted-Average Number of Shares Outstanding, Basic
Increase Decrease In Operating Lease Assets
Increase decrease in operating lease assets
Amount of increase (decrease) in operating lease right-of-use assets.
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Intrinsic Value
Aggregate intrinsic value options exercisable
CODM Description
Segment Reporting, Expense Information Used by CODM, Description
Offering Cost, Expense
Offering cost
Schedule of Share-Based Compensation Arrangements by Share-Based Payment Award [Table]
Schedule Of Share Based Compensation Arrangements By Share Based Payment Award [Table]
Schedule of Operating Leased Assets [Table]
Recoverable research and development tax credits.
Recoverable Research And Development Tax Credits
Recoverable research and development tax credits
Proceeds from Issuance of Private Placement
Issuance of common stock in private placement
Proceeds from issuance of common stock in private placement, net of issuance costs
Subsequent Events
Subsequent Events [Text Block]
Direct transaction costs
Asset Acquisition, Consideration Transferred, Transaction Cost
Related Party Transactions Disclosure [Text Block]
Related Party Transactions
Fair Value Inputs Level 1, 2 and 3 [Member]
Fair Value, Inputs, Level 1, Level 2, and Level 3 [Member]
APIC, Share-based Payment Arrangement, Increase for Cost Recognition, Total
APIC, Share-Based Payment Arrangement, Increase for Cost Recognition
Stock-based compensation
Equity, Attributable to Parent
Ending balance
Beginning balance
Total stockholders' equity
Mabworks Agreement [Member]
Mabworks Agreement [Member]
Mabworks Agreement [Member]
Basis of Accounting, Policy [Policy Text Block]
Basis of Presentation and Principles of Consolidation
Statement of Stockholders' Equity [Abstract]
Cash paid for leases included in operating cash outflows
Cash paid for leases included in operating cash outflows
Cash paid for leases included in operating cash outflows
Series A redeemable convertible preferred stock member.
Series A Redeemable Convertible Preferred Stock [Member]
Series A Redeemable Convertible Preferred Stock [Member]
Type of Restructuring [Domain]
Use of Estimates, Policy [Policy Text Block]
Use of Estimates
Defined Benefit Plan Disclosure [Line Items]
Foreign Currency Transaction Gain (Loss), before Tax, Total
Gain (Loss), Foreign Currency Transaction, before Tax
Unrealized foreign currency transaction loss
Foreign currency (loss)
Total Development And Regulatory Milestones
Total Development And Regulatory Milestones
Total Development And Regulatory Milestones
Entity Address, Address Line Two
Entity Address, Address Line Two
Amount of in-process research and development asset acquired
In-process research and development, related party
Amount of in-process research and development asset acquired in business combination and recognized at acquisition date
Fair Value Disclosures [Text Block]
Fair Value Measurements
Additional Office Space Through 2026 [Member]
Additional Office Space Through 2026 [Member]
Fair market value, common stock percentage
Percentage of fair market value, common stock
Percentage of fair market value of common stock
Entity Incorporation, Date of Incorporation
Entity incorporation date
Schedule of Accrued Liabilities [Table Text Block]
Summary of Accrued Expenses
Debt Instrument, Name [Domain]
Total accrued expenses and other current liabilities
Accrued Liabilities and Other Liabilities
Accrued expenses and other current liabilities
ProBioGen Sales Milestones [Member]
ProBioGen Sales Milestones [Member]
ProBioGen Sales Milestones Member
Segment Reporting, CODM, Individual Title and Position or Group Name [Extensible Enumeration]
Sublease Income [Member]
Sublease Income [Member]
Plan Name [Domain]
Plan Name
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items]
Temporary equity automatic conversion sale of common stock gross proceeds.
Temporary Equity Automatic Conversion Sale Of Common Stock Gross Proceeds
Temporary equity, automatic conversion, sale of common stock, gross proceeds
Business Description and Basis of Presentation [Text Block]
Nature of Operations and Basis of Presentation
Business Combination, Recognized Liability Assumed, Liability [Abstract]
Liabilities assumed
Restructuring Plan [Axis]
Related and Nonrelated Parties [Axis]
Asset Acquisition and Private Placement with a Related Party
Asset Acquisition [Text Block]
Total Marketable Securities [Member]
Total Marketable Securities [Member]
Total Marketable Securities [Member]
Entity Address, City or Town
Entity Address, City or Town
Incremental Share Based Compensation Expense
Incremental ShareBasedCompensationExpense
Incremental ShareBasedCompensationExpense
Share Based Compensation Arrangement By Share Based Payment Award, Equity Instruments Other Than Options, Grants In Period, Total, Fair Value
Share Based Compensation Arrangement By Share Based Payment Award, Equity Instruments Other Than Options, Grants In Period, Total, Fair Value
Aggregate fair value of share based awards granted during the period.
Number of Reportable Segments
Number of Reportable Segments
Security Exchange Name
Security Exchange Name
Schedule of Redeemable Convertible Preferred Stock
Temporary Equity [Table Text Block]
Aggregate Loan Commitment Amount
Aggregate Loan Commitment Amount
Aggregate principal amount
Aggregate Loan Commitment Amount
Aggregate Gross Sales Proceeds Under Sales Agreements
The aggregate gross sales proceeds available under a sales agreement to sell shares of the Company's common stock.
Aggregate gross sales proceeds under sales agreement
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Outstanding, Number
Number of options, vested and expected to vest
Antidilutive Securities, Name [Domain]
Antidilutive Securities, Name
Redeemable convertible preferred stock tranche liability.
Redeemable Convertible Preferred Stock Tranche Liability [Member]
Redeemable Convertible Preferred Stock Tranche Liability [Member]
ProBioGen Manufacturing Service [Member]
ProBioGen Manufacturing Service [Member]
ProBioGen Manufacturing Service Member
Series A Athenen acquisition redeemable convertible preferred stock member.
Series A Athenen Acquisition Redeemable Convertible Preferred Stock [Member]
Series A Athenen Acquisition Redeemable Convertible Preferred Stock [Member]
Cash, Cash Equivalents, Restricted Cash and Restricted Cash Equivalents, Total
Cash, Cash Equivalent, Restricted Cash, and Restricted Cash Equivalent, Continuing Operation
Cash and cash equivalents at beginning of period
Cash and cash equivalents at end of period
Statistical Measurement [Domain]
Statistical Measurement
Exercise price
Class of Warrant or Right, Exercise Price of Warrants or Rights
Assets, Current
Total current assets
Share-Based Payment Arrangement, Expense
Total stock-based compensation expense
Stock Based Compensation Expense
Aggregate Loan Proceeds
Aggregate Loan Proceeds
Aggregate loan proceeds
Document Period End Date
Document Period End Date
Title and Position [Axis]
Fair Value Hierarchy and NAV [Domain]
Fair Value Hierarchy and NAV
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Number
Number of options exercisable, end of period
Net Operating Lease Payments [Member]
Net Operating Lease Payments [Member]
Accrued Interest Receivable
Accrued Interest Receivable
Accrued Interest Receivable
Statement of Financial Position [Abstract]
Restricted Stock Units
Restricted Stock Units (RSUs) [Member]
Business Combination, Recognized Asset Acquired, Asset [Abstract]
Assets acquired
Redeemable Convertible Preferred Stock [Member]
Redeemable Convertible Preferred Stock [Member]
Antidilutive Security, Excluded EPS Calculation [Table]
Schedule Of Antidilutive Securities Excluded From Computation Of Earnings Per Share [Table]
Class of Stock
Class of Stock [Axis]
Debt Securities, Available-for-sale, Realized Gain (Loss), Total
Debt Securities, Available-for-Sale, Realized Gain (Loss)
Realized gain or loss on available-for-sale securities
Liabilities
Total liabilities
Restructuring Costs [Member]
Restructuring Costs [Member]
Restructuring Costs [Member]
US Government Debt Securities [Member]
US Government Debt Securities [Member]
U.S. Government debt securities
Financial Instruments [Domain]
Restructuring costs incurred during the period
Restructuring and Related Cost, Incurred Cost
Share-based payment award, description
Share-Based Compensation Arrangement by Share-Based Payment Award, Description
Other-than-temporary Impairment Loss, Debt Securities, Available-for-sale, Total
Other-than-temporary Impairment Loss, Debt Securities, Available-for-Sale
Impairment loss on available for sale investment
2027
Lessee, Operating Lease, Liability, to be Paid, Year Two
Restricted Stock [Member]
Restricted Stock
Initial Loan
Initial Loan [Member]
Initial Loan [Member]
Weighted Average Number of Shares Outstanding, Diluted, Total
Weighted Average Number of Shares Outstanding, Diluted
Weighted-average number of shares used to compute net loss per share, diluted
Weighted-Average Number of Shares Outstanding, Diluted
Entity File Number
Entity File Number
Eliem Therapeutics [Member]
Eliem Therapeutics [Member]
Other Assets, Total
Other Assets
Other assets
Cover [Abstract]
Other Expenses
Accounts payable and accrued liabilities, related party
Increase (Decrease) in Accounts Payable and Accrued Liabilities
Increase (Decrease) in Accounts Payable and Accrued Liabilities, Total
Prepaid Expense and Other Assets, Current
Prepaid expenses and other current assets
Total prepaid expenses and other current assets
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Forfeited in Period
Number of shares, Forfeited
Number of shares, Forfeited
Accrued expenses and other current liabilities
Business Combination, Recognized Liability Assumed, Other Liability, Current
Two Thousand Twenty Five Inducement Plan [Member]
Two Thousand Twenty Five Inducement Plan [Member]
2025 Inducement Plan
Supplemental Balance Sheet Disclosures [Text Block]
Accrued payroll and related expenses
Workforce reduction, percentage
Percentage of Workforce Reduction
Percentage of Workforce Reduction
Unrealized Gain (Loss), Foreign Currency Transaction, before Tax
Unrealized foreign currency transaction loss
US Treasury Securities [Member]
U.S Treasury Securities
Share-Based Compensation Arrangement by Share-Based Payment Award, Number of Shares Authorized
Share-based payment award, number of shares authorized
Number of operating segments
Number of Operating Segments
Sale of Stock [Domain]
Sale of Stock
Segments
Segment Reporting Disclosure [Text Block]
General and administrative
General and Administrative Expense
General and Administrative Expense, Total
General and Administrative Expense
Series B Preferred Stock [Member]
Temporary Equity, Liquidation Preference
Temporary Equity, Liquidation Preference
Subsequent Event [Table]
Business Combination, Recognized Liability Assumed, Accounts Payable, Current
Accounts payable
Operating Lease, Expense
Non-cash operating lease expense
Marketable Securities [Abstract]
Acquired In Process Research and Development Expenses
The amount of in-process research and development assets acquired during the period.
Acquired in-process research and development, related party
In-process research and development, related party
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Outstanding, Weighted Average Exercise Price
Weighted average exercise price, options vested and expected to vest
Termination charges
Restructuring Charges
Restructuring costs
Total Restructuring Charges
Milestone [Member]
Milestone [Member]
New Accounting Pronouncements, Policy [Policy Text Block]
Recent Accounting Pronouncements
Recently Issued Accounting Pronouncements Not Yet Adopted
Lessee, Operating Lease, Liability, to be Paid, Maturity [Table Text Block]
Future Minimum Lease Payments Under Non-Cancelable Operating Leases
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]
Antidilutive Securities Excluded From Computation Of Earnings Per Share [Line Items]
Ownership [Axis]
Share-based payment award, option vesting period
Share-based payment award, option vesting period
Employee Severance [Member]
Share-Based Payment Arrangement, Nonvested Award, Excluding Option, Cost Not yet Recognized, Amount
Share based payment arrangement nonvested award excluding option cost not yet recognized
Organization, Consolidation and Presentation of Financial Statements Disclosure and Significant Accounting Policies [Text Block]
Organization
Common Stock, Shares, Outstanding, Beginning Balance
Common Stock, Shares, Outstanding, Ending Balance
Common Stock, Shares, Outstanding
Common stock, shares outstanding
Operating lease liabilities
Operating Lease, Liability, Current
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Depreciation, Depletion and Amortization
Depreciation, Depletion and Amortization, Total
Depreciation and amortization expense
Document Transition Report
Document Transition Report
Total operating expenses
Operating Expenses
Research and development
Research and Development Expense
Research and development Expense
Total research and development expenses
Debt Securities, Available-for-Sale, Amortized Cost, Current
Amortized Cost, Short-term marketable securities
Stock Options to Purchase Common Stock [Member]
Stock Options to Purchase Common Stock [Member]
Statement of Cash Flows [Abstract]
At The Market Equity Offering Program [Member]
At The Market Equity Offering Program [Member]
At the market equity offering program [Member]
Acelyrin, Inc. [Member]
Acelyrin, Inc. [Member]
Acelyrin Inc. [Member]
Stock Issued During Period, Value, New Issues
Issuance of common stock, value
Share-Based Payment Arrangement, Option, Activity [Table Text Block]
Summary of Stock Option Activities
Assets, Fair Value Disclosure [Abstract]
Assets:
Payments to Acquire Businesses, Net of Cash Acquired
Payments to Acquire Businesses, Net of Cash Acquired, Total
Cash paid in connection with asset acquisition, net of cash received
Stock-based Compensation [Member]
Stock-based Compensation [Member]
Stock-based Compensation [Member]
Net Loss Per Share
Earnings Per Share [Text Block]
Temporary Equity [Line Items]
Temporary Equity [Line Items]
Share-Based Payment Arrangement, Restricted Stock Unit, Activity [Table Text Block]
Summary of Restricted Stock Awards
Gross proceeds
Sale of Stock, Consideration Received Per Transaction
Net loss attributable to common stockholders
Net loss
Initial Loan Receivable Amount
Initial Loan Receivable Amount
Initial loan amount
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Intrinsic Value
Aggregate intrinsic value outstanding, end of period
Aggregate intrinsic value outstanding, beginning of period
Entity incorporation date
Date Of Incorporation
Date of incorporation.
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Dividend Rate
Dividend yield
Earnings Per Share, Basic, by Common Class, Including Two Class Method [Line Items]
Exchange ratio
Exchange Ratio
Exchange Ratio
Exchange Agreement [Member]
Exchange Agreement [Member]
Exchange Agreement [Member]
Assets
Assets [Abstract]
Risk-free interest rate
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Risk Free Interest Rate
Restructuring and Related Activities [Abstract]
Document Fiscal Year Focus
Document Fiscal Year Focus
After First Anniversary Member
After First Anniversary [Member]
After First Anniversary Member
Cash Provided by (Used in) Investing Activity, Including Discontinued Operation [Abstract]
Cash flow from investing activities:
Accounts Payable, Current, Total
Accounts Payable, Current
Accounts payable
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested in Period, Fair Value
Research and Development Expense [Member]
Research and Development Expense
Marketable Securities
Investments in Debt and Marketable Equity Securities (and Certain Trading Assets) Disclosure [Text Block]
Direct Expense [Member]
Direct Expense [Member]
Direct Expense [Member]
Increase (Decrease) in Other Noncurrent Assets
Other long-term assets
Settlement of promissory loan in connection with asset acquisition
Amount of promissory loan settled in connection with an asset acquisition
Amount of promissory loan settled in connection with an asset acquisition
Risks and Uncertainties
Risks And Uncertainties In Entitys Busines
Risks And Uncertainties In Entitys Busines
Restructuring Cost and Reserve [Line Items]
Fair Value Measurement, Policy [Policy Text Block]
Fair Value Measurements
Additional Office Space Through 2027 [Member]
Additional Office Space Through 2027 [Member]
Temporary Equity Disclosure [Abstract]
Proceeds from Stock Options Exercised
Proceeds from exercise of stock options
Fair Value Disclosures [Abstract]
Commitments and Contingencies Disclosure [Abstract]
Lessee, Operating Lease, Liability, to be Paid, Year One
2026
Business Combination, Recognized Asset Acquired to Liability Assumed, Excess (Less)
Business Combination, Recognized Identifiable Assets Acquired and Liabilities Assumed, Net, Total
Net assets acquired
Gross Operating Lease Payments [Member]
Gross Operating Lease Payments [Member]
Tabular disclosure of information about valuation of redeemable convertible preferred stock tranche liability.
Schedule Of Valuation Of The Redeemable Convertible Preferred Stock Tranche Liability Table [Text Block]
Schedule of Valuation of the Redeemable Convertible Preferred Stock Tranche Liability
Available Sale Securities
Available Sale Securities
Available for Sale Securities
Debt Instrument [Axis]
Share-Based Payment Arrangement [Abstract]
Share-Based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Amount
Share-Based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Amount, Total
Unrecognized compensation cost
Assets, Fair Value Disclosure, Total
Assets, Fair Value Disclosure
Assets fair value
Temporary Equity Estimated Fair Value Of Redeemable Convertible Preferred Stock
Temporary equity estimated fair value of redeemable convertible preferred stock.
Estimated fair value of redeemable convertible preferred stock
Sale of Stock [Axis]
Sale of Stock
Temporary Equity, Liquidation Preference Per Share
Temporary equity liquidation preference
Temporary equity, per share
Series A 1 Tranche Call Option [Member]
Series A 1 tranche call option.
Series A1 Tranche Call Option [Member]
Personnel Related [Member]
Personnel Related [Member]
Personnel Related [Member]
Cash Provided by (Used in) Investing Activity, Including Discontinued Operation
Net cash used in investing activities
Private Placement [Member]
Private Placement [Member]
Title of 12(b) Security
Title of 12(b) Security
Schedule of Segment Reporting Information, by Segment [Table]
Gain Contingencies [Table]
Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Forfeitures in Period, Weighted Average Exercise Price
Weighted average exercise price, options forfeited
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Forfeitures, Weighted Average Grant Date Fair Value
Forfeited, weighted average grant date fair value per share
Money Market Funds [Member]
Money Market Funds
Related and Nonrelated Parties [Domain]
Collaborative Arrangement and Arrangement Other than Collaborative [Table]
Temporary Equity, Shares Issued
Temporary Equity, Shares Issued
Total Restructuring Cost Recorded [Member]
Total Restructuring Cost Recorded [Member]
Lessee, Operating Lease, Liability, to be Paid, Remainder of Fiscal Year
2025 (remaining 9 months)
Restructuring Plan [Domain]
Adjustment to Reconcile Net Income to Cash Provided by (Used in) Operating Activity, Increase (Decrease) in Operating Capital [Abstract]
Changes in operating assets and liabilities:
Business Combination, Price Per Share
Share price
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Exercise Price
Weighted average exercise price outstanding, end of period
Weighted average exercise price outstanding, beginning of period
Weighted average exercise price, options cancelled and forfeited
Fair Value, Recurring and Nonrecurring [Table]
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Table]
Series A 1 redeemable convertible preferred tranche liability.
Series A1 Redeemable Convertible Preferred Tranche Liability [Member]
Series A 1 Redeemable Convertible Preferred Tranche Liability
Additional Paid-in Capital [Member]
Additional Paid-in Capital [Member]
Accrued expenses and other current liabilities
Increase (Decrease) in Accrued Liabilities and Other Operating Liabilities
Measurement Frequency [Domain]
Last Day of Offering Period [Member]
Last Day of Offering Period [Member]
Statement of Income Location, Balance [Axis]
Income Statement Location
Trading Symbol
Trading Symbol
Related Party Transaction [Table]
Development Manufacturing and Commercial [Member]
Development Manufacturing and Commercial [Member]
Subsequent Event Type [Axis]
Subsequent Event Type
Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Period Increase (Decrease), Total
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Period Increase (Decrease)
Stock Option Award Outstanding
Accrued payroll and related expenses
Employee-related Liabilities, Current
Employee-related Liabilities, Current, Total
Cash Provided by (Used in) Financing Activity, Including Discontinued Operation [Abstract]
Cash flows from financing activities
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Term
Expected term (in years)
Fair Value, Recurring [Member]
Fair Value, Recurring
Entity Ex Transition Period
Entity Ex Transition Period
Lessee, Operating Lease, Liability, to be Paid
Total undiscounted lease payments
Additional fixed payments
Expected term (years)
Temporary Equity Expected Term
Temporary equity expected term.
Aggregate Beneficial Ownership Exchanging Stockholders
The aggregate amount of beneficial ownership that exchanging shareholders may own to be eligible to exercise pre-funded warrants, as a percentage of shares issued and outstanding.
Aggregate Beneficial Ownership Exchanging Stockholders
Financing Receivable Portfolio Segment [Domain]
Equity Components [Axis]
Equity Components
Development and Regulatory Milestones [Member]
Development and Regulatory Milestones [Member]
Nonoperating Income (Expense)
Total other income, net
Equity Component [Domain]
Equity Component
Stock issued during period shares new issues
Temporary equity stock issued during period shares new issues.
Temporary Equity Stock Issued During Period Shares New Issues
Business Combination [Axis]
IPO [Member]
IPO [Member]
Share Based Compensation Arrangement By Share Based Payment Award Annual Increase Percentage
The automatic increase in the number of shares that may be issued under a share-based payment arrangement on the first day of each fiscal year, as a percentage of shares outstanding
Number of Shares of Common Stock Outstanding Percentage
Stock Issued During Period, Shares, Employee Stock Purchase Plans
Stock issued during period shares employee stock purchase plans
Share-Based Compensation Arrangement by Share-Based Payment Award, Expiration Period
Share-based payment award, expiration period
Collaborative Arrangement, Accounting Policy [Policy Text Block]
Collaborative arrangement accounting
Maximum [Member]
Maximum [Member]
Liabilities, Fair Value Disclosure, Total
Liabilities, Fair Value Disclosure
Liabilities fair value
Two thousand twenty one equity incentive plan.
Two Thousand Twenty One Equity Incentive Plan [Member]
2021 Equity Incentive Plan
Statistical Measurement [Axis]
Statistical Measurement
Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Exercises in Period, Weighted Average Exercise Price
Weighted average exercise price, options exercised
Prepaid expenses
Prepaid Expense, Current, Total
Prepaid Expense, Current
Common Stock, Value, Issued, Ending Balance
Common Stock, Value, Issued, Beginning Balance
Common Stock, Value, Issued, Total
Common Stock, Value, Issued
Common stock, $0.0001 par value; 250,000,000 shares authorized; 47,768,543 and 47,766,338 shares issued and outstanding at March 31, 2026 and December 31, 2025, respectively
Commercial Milestones [Member]
Commercial Milestones [Member]
Unallocated Expense [Member]
Unallocated Expense [Member]
Unallocated Expense [Member]
Consolidation, Policy [Policy Text Block]
Basis of Presentation and Principles of Consolidation
2026 Private Placement [Member]
Two Thousand Twenty Six Private Placement [Member]
Two Thousand Twenty Six Private Placement [Member]
Comprehensive loss:
Comprehensive Income (Loss), Net of Tax, Attributable to Parent [Abstract]
Marketable Securities [Line Items]
Other income (expense):
Other Nonoperating Income (Expense) [Abstract]
Entity Public Float
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Volatility Rate
Expected volatility
Strike price
Temporary Equity Strike Price
Temporary equity strike price
Temporary Equity, Accretion to Redemption Value, Adjustment
Accretion of redeemable convertible preferred stock to redemption value
Related Party Transaction [Line Items]
Employee Stock
Employee Stock [Member]
Entity Registrant Name
Entity Registrant Name
Issuance of promissory loan in connection with asset acquisition
Issuance Of Promissory Loan In Connection With Asset Acquisition To Related Party
Issuance Of Promissory Loan In Connection With Asset Acquisition To Related Party
Debt Securities, Available-for-Sale, Accumulated Gross Unrealized Loss, before Tax
Unrealized Loss
Unrealized Loss
Fair Value, Measurement with Unobservable Inputs Reconciliation, Recurring Basis, Asset, Transfers, Net
Fair Value, Measurement with Unobservable Inputs Reconciliation, Recurring Basis, Asset, Transfers, Net
Fair Value, Measurement with Unobservable Inputs Reconciliation, Recurring Basis, Asset, Transfers, Net, Total
Subsequent Events [Abstract]
Income tax
Income Tax Expense (Benefit)
Income Tax Expense (Benefit), Total
Measurement Frequency [Axis]
Temporary equity disclosure text block.
Temporary Equity Disclosure [Text Block]
Redeemable Convertible Preferred Stock
Change in fair value of redeemable convertible preferred stock tranche liability.
Change In Fair Value Of Redeemable Convertible Preferred Stock Tranche Liability
Change in fair value of redeemable convertible preferred stock tranche liability
Change in fair value of redeemable convertible preferred stock tranche liability
Change in fair value
Proceeds from Issuance of Common Stock
Proceeds from Issuance of Common Stock
Proceeds from exercise of stock options
Other Comprehensive Income (Loss), Tax [Abstract]
Other comprehensive income:
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Subsidiary, Ownership Percentage, Noncontrolling Owner
Minority Interest Ownership Percentage By Non controlling Owners
Entity Common Stock, Shares Outstanding
Concentration Risk, Credit Risk, Policy [Policy Text Block]
Concentration of Credit Risk and Significant Suppliers and Manufacturers
Liability Class [Axis]
Liability Class
Cash, cash equivalents and marketable securities
Cash Cash Equivalents and Marketable Securities
Cash Cash Equivalents and Marketable Securities.
Accumulated Other Comprehensive Income (Loss), Net of Tax, Total
Accumulated Other Comprehensive Income (Loss), Net of Tax
Accumulated other comprehensive loss
Consolidation Items [Axis]
Stephen Thomas [Member]
Stephen Thomas [Member]
Stephen Thomas [Member]
Restructuring costs paid during the period
Payment related to continuation of health care
Payments for Restructuring
Purchases of property and equipment
Payments to Acquire Property, Plant, and Equipment
Payments to Acquire Property, Plant, and Equipment, Total
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Grants in Period
Number of shares, Granted
Series B Redeemable Convertible Preferred Stock [Member]
Series B redeemable convertible preferred stock member .
Series B Redeemable Convertible Preferred Stock [Member]
Temporary Equity, by Class of Stock [Table]
Temporary Equity By Class Of Stock [Table]
Assets
Total assets
Assets fair value
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Weighted Average Remaining Contractual Term
Weighted average remaining contractual terms (in years), exercisable at end of period
Income Statement [Abstract]
Restructuring Cost [Table]
Development Regulatory and Commercial Milestones [Member]
Development Regulatory and Commercial Milestones [Member]
Expected volatility
Temporary Equity Expected Volatility
Temporary equity expected volatility.
Stock Issued During Period, Shares, New Issues
Issuance of common stock
Proceeds from issuance of common stock in initial public offering, Shares
Temporary Equity, Shares Authorized
Temporary Equity, Shares Authorized
Number of shares, Vested
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Vested in Period
Business Combination [Abstract]
Earnings Per Share, Diluted
Earnings Per Share, Diluted, Total
Net loss per share, Diluted
Redemption date
Preferred Stock, Redemption Date
Schedule of Segment Reporting Information, by Segment [Table Text Block]
Schedule of Forth Disaggregated Research and Development Expenses
Operating Segments [Member]
Operating Segments [Member]
Title and Position [Domain]
Unit conversion ratio
Preferred Stock, Conversion Basis
City Area Code
City Area Code
Fair value of each tranche feature
Temporary Equity Fair Value Of Each Tranche Feature
Temporary equity fair value of each tranche feature.
ProBioGen Agreement [Member]
ProBioGen Agreement [Member]
ProBioGen Agreement [Member]
Defined Benefit Plan [Table]
Upfront Payment [Member]
Upfront Payment [Member]
Upfront Payment [Member]
Reclassification Of Redeemable Convertible Preferred Stock Tranche Liability Upon Settlement
Reclassification of redeemable convertible preferred stock tranche liability upon settlement
Reclassification of redeemable convertible preferred stock tranche liability upon settlement.
Settlement upon issuance of Series A-1 redeemable convertible preferred stock
Segment Reporting Information [Line Items]
Stock Issued During Period, Shares, Restricted Stock Award, Gross
Vesting of restricted stock units
Termination Fees
Termination Fees
Termination fees
Award Date [Axis]
Investments [Abstract]
Equity consideration
Business Combination, Consideration Transferred, Equity Interest
Property, Plant and Equipment, Net
Property, Plant and Equipment, Net, Total
Property and equipment, net
Corporate Bond Securities [Member]
Corporate bonds
Corporate Bonds
Operating Income (Loss)
Loss from operations
Award Date [Domain]
Retained Earnings [Member]
Accumulated Deficit [Member]
Cash, cash equivalents and marketable securities
Cash Cash Equivalent And Marketable Securities
Amount of cash, cash equivalents and marketable securities as of the balance sheet date.
Cash and Cash Equivalents [Axis]
Tenet Stock Owned By RA Capital [Member]
Tenet Stock Owned By RA Capital [Member]
Tenet Stock Owned By RA Capital [Member]
Series A1 Preferred Stock [Member]
Series A - 1 Preferred Stock
Series A - 1 preferred stock member.
Share-based Payment Arrangement, Noncash Expense, Total
Share-Based Payment Arrangement, Noncash Expense
Stock-based compensation expense
Percentage of cumulative dividends receive
Cumulative Dividends Receive
Cumulative dividends receive.
Employees Including Executive Officers Earning Contribution
Employees Including Executive Officers Earning Contribution
Employees Including Executive Officers Earning Contribution
Continuous unrealized loss position, less than 12 months
Debt Securities, Available-for-Sale, Continuous Unrealized Loss Position, Less than 12 Months
Temporary Equity Probability Of Milestone Achievement
Probability of milestone achievement
Temporary equity probability of milestone achievement.
Note Purchase Agreement [Member]
Note Purchase Agreement
Note Purchase Agreement [Member]
Operating Lease, Liability, Noncurrent
Operating lease liabilities, net of current portion
Fair Value, Inputs, Level 1 [Member]
Level 1 [Member]
Level 1
Cash Provided by (Used in) Financing Activity, Including Discontinued Operation
Net cash provided by financing activities
Ending Balance
Beginning Balance
Redeemable Convertible Preferred Stock Tranche Liability
Redeemable Convertible Preferred Stock Tranche Liability
Redeemable convertible preferred stock tranche liability
Schedule of Antidilutive Securities Excluded from Computation of Net Loss Per Share Attributable to Common Stockholders
Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table Text Block]
Debt Securities, Available-for-Sale [Table]
Entity Interactive Data Current
Entity Interactive Data Current
Statement of Income Location, Balance [Domain]
Income Statement Location
Cash Provided by (Used in) Operating Activity, Including Discontinued Operation [Abstract]
Cash flows from operating activities:
Asset Acquisition [Line Items]
Accretion of discounts and amortization of premiums on investments, net
Accretion (Amortization) of Discounts and Premiums, Investments
Accretion of discounts on marketable securities, net
Severance and Benefits Costs [Member]
Severance and Benefits Costs [Member]
Severance and Benefits Costs [Member]
Increase (Decrease) in Other Noncurrent Liabilities
Long-term liabilities
Option Indexed to Issuer's Equity, Type [Domain]
Option Indexed to Issuer's Equity, Type
Entity Tax Identification Number
Entity Tax Identification Number
Debt Instrument, Term
Loan term
CRH Agreement [Member]
CRH Agreement [Member]
CRH Agreement [Member]
Unrealized gain on marketable securities
Marketable Security, Unrealized Gain (Loss)
Unrealized gain (loss) on marketable securities
Local Phone Number
Local Phone Number
Related Party Transaction [Domain]
Share-Based Payment Arrangement, Nonvested Award, Option, Cost Not yet Recognized, Amount
Unrecognized compensation cost
Total Restructuring Costs
Restructuring Costs
Performance based vesting [Member]
Performance based vesting [Member]
Stock issuance cost
Adjustments to Additional Paid in Capital, Stock Issued, Issuance Costs
Offering cost
Risks and Uncertainties in Entity's Business
Risks and Uncertainties
Dividend yield
Temporary Equity Dividend Yield
Temporary equity dividend yield.
Accounting Policies [Abstract]
Manufacturing Services [Member]
Manufacturing Services [Member]
Earnings Per Share, Basic, by Common Class, Including Two-Class Method [Table]
Shares Exchanged For Pre Funded Warrants
The number of shares exchanged during the period for pre-funded warrants.
Exchange of common stock for pre-funded warrant, Shares
Class of Stock [Domain]
Class of Stock
Commercial Paper [Member]
Commercial Paper [Member]
Commercial paper
Share-Based Compensation Arrangement by Share-Based Payment Award, Number of Shares Available for Grant
Number shares remaining for issuance
Share-Based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Period for Recognition
Unrecognized compensation, weighted average amortization period
Accrued professional fees
Accrued Professional Fees, Current
Schedule of Accounts Payable and Accrued Liabilities [Table Text Block]
Summary of Accrued Expenses
Entity Emerging Growth Company
Entity Emerging Growth Company
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Outstanding, Weighted Average Remaining Contractual Term
Weighted average remaining contractual terms (in years), vested and expected to vest