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  <xs:element id="imcr_DeferredStockSharesIssued" abstract="false" name="DeferredStockSharesIssued" nillable="true" xbrli:periodType="instant" substitutionGroup="xbrli:item" type="xbrli:sharesItemType"/>
  <xs:element id="imcr_DeferredStockSharesOutstanding" abstract="false" name="DeferredStockSharesOutstanding" nillable="true" xbrli:periodType="instant" substitutionGroup="xbrli:item" type="xbrli:sharesItemType"/>
  <xs:element id="imcr_SaleOfTherapiesMember" abstract="true" name="SaleOfTherapiesMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="imcr_DeferredSharesMember" abstract="true" name="DeferredSharesMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="imcr_AccrualsForRebatesChargebacksAndReturnsTableTextBlock" abstract="false" name="AccrualsForRebatesChargebacksAndReturnsTableTextBlock" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:textBlockItemType"/>
  <xs:element id="imcr_NumberOfCountriesKIMMTRAKIsApproved" abstract="false" name="NumberOfCountriesKIMMTRAKIsApproved" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:integerItemType"/>
  <xs:element id="imcr_NumberOfCountriesKIMMTRAKIsCommerciallyLaunched" abstract="false" name="NumberOfCountriesKIMMTRAKIsCommerciallyLaunched" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:integerItemType"/>
  <xs:element id="imcr_MedisonAndErKimMember" abstract="true" name="MedisonAndErKimMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="imcr_MedisonMember" abstract="true" name="MedisonMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="imcr_NonRefundablePaymentReceived" abstract="false" name="NonRefundablePaymentReceived" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="imcr_ContractWithCustomerContractTerm" abstract="false" name="ContractWithCustomerContractTerm" nillable="true" xbrli:periodType="instant" substitutionGroup="xbrli:item" type="xbrli:durationItemType"/>
  <xs:element id="imcr_InternationalMember" abstract="true" name="InternationalMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="imcr_RebatesMember" abstract="true" name="RebatesMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="imcr_ChargebackMember" abstract="true" name="ChargebackMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="imcr_ProductReturnsMember" abstract="true" name="ProductReturnsMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="imcr_AccrualsForRebatesAndChargebacksRollForward" abstract="true" name="AccrualsForRebatesAndChargebacksRollForward" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="imcr_ProvisionRelatedToSalesInThePeriod" abstract="false" name="ProvisionRelatedToSalesInThePeriod" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="imcr_CreditsAndPaymentsMade" abstract="false" name="CreditsAndPaymentsMade" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="imcr_ClinicalAccrualsCurrent" abstract="false" name="ClinicalAccrualsCurrent" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="imcr_AccruedContractManufacturingCurrent" abstract="false" name="AccruedContractManufacturingCurrent" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="imcr_AccruedCommercialServicesCurrent" abstract="false" name="AccruedCommercialServicesCurrent" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="imcr_ConvertibleSeniorNotesMember" abstract="true" name="ConvertibleSeniorNotesMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="imcr_DebtInstrumentOptionToPurchaseMaximumAdditionalNotes" abstract="false" name="DebtInstrumentOptionToPurchaseMaximumAdditionalNotes" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="imcr_PercentageOfRedemptionPricePrincipalAmount" abstract="false" name="PercentageOfRedemptionPricePrincipalAmount" nillable="true" xbrli:periodType="instant" substitutionGroup="xbrli:item" type="dtr-types:percentItemType"/>
  <xs:element id="imcr_EquityIncentivePlanMember" abstract="true" name="EquityIncentivePlanMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="imcr_ShareBasedCompensationArrangementByShareBasedPaymentAwardAwardVestingRights1" abstract="false" name="ShareBasedCompensationArrangementByShareBasedPaymentAwardAwardVestingRights1" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:sharesItemType"/>
  <xs:element id="imcr_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodMinimumSharePriceGrantDate" abstract="false" name="ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodMinimumSharePriceGrantDate" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:perShareItemType"/>
  <xs:element id="imcr_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodMaximumSharePriceGrantDate" abstract="false" name="ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodMaximumSharePriceGrantDate" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:perShareItemType"/>
  <xs:element id="imcr_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsGrantsInPeriodMinimumExercisePrice" abstract="false" name="ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsGrantsInPeriodMinimumExercisePrice" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:perShareItemType"/>
  <xs:element id="imcr_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsGrantsInPeriodMaximumExercisePrice" abstract="false" name="ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsGrantsInPeriodMaximumExercisePrice" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:perShareItemType"/>
  <xs:element id="imcr_ShareOptionsAndRSUsMember" abstract="true" name="ShareOptionsAndRSUsMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="imcr_EffectiveIncomeTaxRateReconciliationResearchAndDevelopmentExpenditureCreditsPercent" abstract="false" name="EffectiveIncomeTaxRateReconciliationResearchAndDevelopmentExpenditureCreditsPercent" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:percentItemType"/>
  <xs:element id="imcr_NumberOfRevenueStreams" abstract="false" name="NumberOfRevenueStreams" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:integerItemType"/>
  <xs:element id="imcr_ReportableSegmentMember" abstract="true" name="ReportableSegmentMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="imcr_PRAMEProgramsMember" abstract="true" name="PRAMEProgramsMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="imcr_TebentafuspProgramsMember" abstract="true" name="TebentafuspProgramsMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="imcr_InfectiousDiseaseProgramsMember" abstract="true" name="InfectiousDiseaseProgramsMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="imcr_OtherClinicalAndPreClinicalCostsMember" abstract="true" name="OtherClinicalAndPreClinicalCostsMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="imcr_SalariesAndOtherEmployeeRelatedCostMember" abstract="true" name="SalariesAndOtherEmployeeRelatedCostMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="imcr_OtherSellingGeneralAndAdministrativeExpensesMember" abstract="true" name="OtherSellingGeneralAndAdministrativeExpensesMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="imcr_ExternalRDMember" abstract="true" name="ExternalRDMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="imcr_LesseeOperatingLeaseLiabilityToBePaidAfterYearThree" abstract="false" name="LesseeOperatingLeaseLiabilityToBePaidAfterYearThree" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="imcr_LesseeOperatingLeaseLeaseNotYetCommencedLiabilityToBePaid" abstract="false" name="LesseeOperatingLeaseLeaseNotYetCommencedLiabilityToBePaid" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="imcr_PercentageOfValuationUsedForRedemption" abstract="false" name="PercentageOfValuationUsedForRedemption" nillable="true" xbrli:periodType="instant" substitutionGroup="xbrli:item" type="xbrli:pureItemType"/>
  <xs:element id="imcr_DavidBermanMember" abstract="true" name="DavidBermanMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
</xs:schema>
