S-3 S-3ASR EX-FILING FEES 0001651308 BeOne Medicines Ltd. N/A N/A 0001651308 2026-05-01 2026-05-01 0001651308 1 2026-05-01 2026-05-01 0001651308 2 2026-05-01 2026-05-01 iso4217:USD xbrli:pure xbrli:shares

Calculation of Filing Fee Tables

S-3

BeOne Medicines Ltd.

Table 1: Newly Registered and Carry Forward Securities ☐Not Applicable

Security Type

Security Class Title

Fee Calculation or Carry Forward Rule

Amount Registered

Proposed Maximum Offering Price Per Unit

Maximum Aggregate Offering Price

Fee Rate

Amount of Registration Fee

Carry Forward Form Type

Carry Forward File Number

Carry Forward Initial Effective Date

Filing Fee Previously Paid in Connection with Unsold Securities to be Carried Forward

Newly Registered Securities
Fees to be Paid 1 Equity Ordinary Shares, par value $0.0001 per share Other 247,344,344 $ 22.54 $ 5,575,141,513.76 0.0001381 $ 769,927.04
Fees Previously Paid
Carry Forward Securities
Carry Forward Securities 2 Equity Ordinary Shares, par value $0.0001 per share 415(a)(6) 151,536,561 $ 2,998,908,542.19 S-3 333-271762 05/09/2023 $ 209,872.98

Total Offering Amounts:

$ 8,574,050,055.95

$ 769,927.04

Total Fees Previously Paid:

$ 0.00

Total Fee Offsets:

$ 0.00

Net Fee Due:

$ 769,927.04

Offering Note

1

(1a) These shares may be represented by the Registrant's American Depositary Shares ("ADSs"). Each ADS represents 13 Ordinary Shares. ADSs issuable upon deposit of the Ordinary Shares registered hereby were registered pursuant to a separate Registration Statement on Form F-6, as amended (File No. 333-286725). (1b) Estimated solely for the purpose of calculating the registration fee pursuant to Rule 457(c) of the Securities Act, and based on the average of the high and low sale prices of the Registrant's ADSs, as quoted on the NASDAQ Global Select Market, on April 29, 2026.

2

(2a) These shares may be represented by the Registrant's American Depositary Shares ("ADSs"). Each ADS represents 13 Ordinary Shares. ADSs issuable upon deposit of the Ordinary Shares registered hereby were registered pursuant to a separate Registration Statement on Form F-6, as amended (File No. 333-286725). (2b) This registration statement includes 151,536,561 Ordinary Shares ("Carry-Forward Securities") that have previously been registered under our registration statement on Form S-3ASR (File No. 333-271762) filed on May 9, 2023, as amended by the Post-Effective Amendment No. 1 to the Registration Statement on Form S-3ASR filed on May 27, 2025 ("Prior Registration Statement"), and remain unsold. Pursuant to Rule 415(a)(6), the Registrant is carrying forward to this registration statement the Carry-Forward Securities, and no additional filing fee is due with respect to the Carry-Forward Securities included in this registration statement. Pursuant to Rule 415(a)(6), the offering of the Carry-Forward Securities under the Prior Registration Statement will be deemed terminated as of the time of the effectiveness of this registration statement.

Table 2: Fee Offset Claims and Sources ☑Not Applicable
Registrant or Filer Name Form or Filing Type File Number Initial Filing Date Filing Date Fee Offset Claimed Security Type Associated with Fee Offset Claimed Security Title Associated with Fee Offset Claimed Unsold Securities Associated with Fee Offset Claimed Unsold Aggregate Offering Amount Associated with Fee Offset Claimed Fee Paid with Fee Offset Source
Rules 457(b) and 0-11(a)(2)
Fee Offset Claims
Fee Offset Sources
Rule 457(p)
Fee Offset Claims
Fee Offset Sources
Table 3: Combined Prospectuses ☑Not Applicable

Security Type

Security Class Title

Amount of Securities Previously Registered

Maximum Aggregate Offering Price of Securities Previously Registered

Form Type

File Number

Initial Effective Date