ATM Program
ATM Program [Member]
ATM Program
Statistical Measurement
Statistical Measurement [Domain]
Award Timing Predetermined
Award Timing Predetermined [Flag]
Remainder of 2026
Lessee, Operating Lease, Liability, to be Paid, Remainder of Fiscal Year
Asset Class
Asset Class [Axis]
Entity File Number
Entity File Number
Additional Paid-in Capital
Additional Paid-in Capital [Member]
Tabular List, Table
Tabular List [Table Text Block]
Leases [Abstract]
Leases [Abstract]
Recently Issued Accounting Standards Not Yet Adopted
New Accounting Pronouncements, Policy [Policy Text Block]
Supply Commitment [Axis]
Supply Commitment [Axis]
Increase or decrease of pre-funded warrant percentage not exceed (in percentage)
Increase or Decrease of Pre-funded Warrant Percentage Not Exceed
Increase or Decrease of Pre-funded Warrant Percentage Not Exceed
Accounts payable
Increase (Decrease) in Accounts Payable
Taxes paid related to the net share settlement of equity awards
Share-Based Payment Arrangement, Decrease for Tax Withholding Obligation
Gross Unrealized Losses
Debt Securities, Available-for-Sale, Accumulated Gross Unrealized Loss, before Tax
Trading Arrangements, by Individual
Trading Arrangements, by Individual [Table]
2028
Other Commitment, to be Paid, Year Two
Net loss per share, basic (in dollars per share)
Earnings Per Share, Basic
Adjustment to Compensation:
Adjustment to Compensation [Axis]
Accrued payment
Accrued Payment
Accrued payment
Mr. Pickering [Member]
Mr. Pickering
Named Executive Officers, Footnote
Named Executive Officers, Footnote [Text Block]
Commercial paper
Commercial Paper [Member]
Schedule Of Stock By Class [Table]
Stock, Class of Stock [Table]
Schedule of Disaggregation of Income Statement Expenses
Schedule of Segment Reporting Information, by Segment [Table Text Block]
Issuance of common stock in connection with employee incentive plans (in shares)
Stock Issued During Period, Shares, Employee Stock Purchase Plans
Combined voting power of securities outstanding immediately after effect to the exercise (in percentage)
Combined Voting Power of Securities Outstanding Immediately after Effect to the Exercise
Combined voting power of securities outstanding immediately after effect to the exercise.
Adjustment to Compensation, Amount
Adjustment to Compensation Amount
Other assets
Increase (Decrease) in Other Operating Assets
Stock-based compensation expense
Share-Based Payment Arrangement, Noncash Expense
Proceeds from issuance of common stock from follow-on offering, net of issuance costs
Proceeds From Issuance Of Common Stock From Follow-On Offering, Net Of Issuance Costs
Proceeds from issuance of common stock from follow-on offering, net of issuance costs.
Employee Stock Option
Stock options
Share-Based Payment Arrangement, Option [Member]
Award Timing MNPI Disclosure
Award Timing MNPI Disclosure [Text Block]
Aggregate offering price
Sale Of Common Stock Authorized Amount
Sale of common stock authorized amount.
Antidilutive Securities
Antidilutive Securities [Axis]
Total stockholders' equity
Beginning balance
Ending balance
Equity, Attributable to Parent
Measurement Frequency
Measurement Frequency [Axis]
Insider Trading Policies and Procedures [Line Items]
Total stock-based compensation expense
Share-Based Payment Arrangement, Expense
Common stock, shares authorized (in shares)
Common Stock, Shares Authorized
2020 Plan and 2014 Plan
Two Thousand Twenty Equity Incentive Plan And Two Thousand Fourteen Equity Incentive Plan [Member]
Two thousand twenty equity incentive plan and two thousand fourteen equity incentive plan.
Issuance of common stock in connection with follow-on public offering, net of commissions and offering expenses (in shares)
Common stock shares sold (in shares)
Stock Issued During Period, Shares, New Issues
Current assets:
Assets, Current [Abstract]
Options forfeited (in shares)
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Forfeitures in Period
Total liabilities and stockholders' equity
Liabilities and Equity
Antidilutive Securities Excluded From Computation Of Earnings Per Share [Line Items]
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]
Fair value, recurring
Fair Value, Recurring [Member]
Number of Options
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding [Roll Forward]
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding [Roll Forward]
Liabilities and Stockholders' Equity
Liabilities and Equity [Abstract]
Other income, net:
Other Nonoperating Income (Expense) [Abstract]
Cover [Abstract]
Cover [Abstract]
Fair Value
Cash and Cash Equivalents, Fair Value Disclosure
Maximum
Maximum [Member]
General and administrative
General and Administrative Expense [Member]
Weighted-Average Exercise Price Per Share, Exercisable (in dollars per share)
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Weighted Average Exercise Price
Unvested Employee And Non-Employee Awards
Unvested Employee And Non-Employee Awards [Member]
Unvested Employee And Non-Employee Awards
Accounting Policies [Abstract]
Accounting Policies [Abstract]
Investments in fair market value, unrealized loss position
Debt Securities, Available-for-Sale, Unrealized Loss Position
Schedule of Maturities of Lease Liabilities
Lessee, Operating Lease, Liability, to be Paid, Maturity [Table Text Block]
Non-PEO NEO Average Total Compensation Amount
Non-PEO NEO Average Total Compensation Amount
Schedule Of Share Based Compensation Arrangements By Share Based Payment Award [Table]
Schedule of Share-Based Compensation Arrangements by Share-Based Payment Award [Table]
CARB-X Agreement
Combating Antibiotic Resistant Bacteria Biopharmaceutical Accelerator Agreement [Member]
Combating antibiotic resistant bacteria biopharmaceutical accelerator agreement.
Adjustment to Non-PEO NEO Compensation Footnote
Adjustment to Non-PEO NEO Compensation Footnote [Text Block]
Pay vs Performance Disclosure [Line Items]
Total lease liabilities
Operating Lease, Liability
U.S. government agency securities
US Government Agencies Debt Securities [Member]
Forgone Recovery due to Disqualification of Tax Benefits, Amount
Forgone Recovery due to Disqualification of Tax Benefits, Amount
Number of common stock issued (in shares)
Stock Issued During Period, Shares, Issued for Services
Non-Rule 10b5-1 Arrangement Terminated
Non-Rule 10b5-1 Arrangement Terminated [Flag]
Entity Shell Company
Entity Shell Company
Shares Of Common Stock Held By Trust [Member]
Shares Of Common Stock Held By Trust
Statement of Stockholders' Equity [Abstract]
Statement of Stockholders' Equity [Abstract]
Patheon Commercial Manufacturing and Supply Agreement
Patheon Commercial Manufacturing and Supply Agreement [Member]
Patheon Commercial Manufacturing and Supply Agreement
Accrued contract manufacturing expenses
Increase Decrease In Accrued Contract Manufacturing Expenses
Increase decrease in accrued contract manufacturing expenses.
Accrued compensation
Increase Decrease In Accrued Compensation
Increase decrease in accrued compensation.
Statement of Cash Flows [Abstract]
Statement of Cash Flows [Abstract]
Company Selected Measure Amount
Company Selected Measure Amount
2029
Lessee, Operating Lease, Liability, to be Paid, Year Three
Award Timing MNPI Considered
Award Timing MNPI Considered [Flag]
Total assets measured at fair value, amortized cost
Cash And Cash Equivalents And Investments Amortized Cost Basis
Cash and cash equivalents and investments amortized cost basis.
Comprehensive loss
Comprehensive Income (Loss), Net of Tax, Attributable to Parent
Amortized Cost
Cash And Cash Equivalents Amortized Cost
Cash and cash equivalents amortized cost.
Name
Measure Name
Due in less than one year
Debt Securities, Available-for-Sale, Fair Value, Maturity, Allocated and Single Maturity Date, Year One
Operating lease liabilities — current
Operating Lease, Liability, Current
Maturities of investments
Proceeds from Maturities, Prepayments and Calls of Debt Securities, Available-for-Sale
Class of Stock [Line Items]
Class of Stock [Line Items]
Document Fiscal Period Focus
Document Fiscal Period Focus
Award Timing Method
Award Timing Method [Text Block]
Automatic renewal period, advanced notice period
Automatic Renewal Period, Advanced Notice Period
Automatic Renewal Period, Advanced Notice Period
Award Type
Award Type [Axis]
Total assets
Assets
New Corporate Headquarters Facility
New Corporate Headquarters Facility [Member]
New Corporate Headquarters Facility.
Trading Symbol
Trading Symbol
2030
Lessee, Operating Lease, Liability, to be Paid, Year Four
Vested and released (in dollars per share)
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Vested in Period, Weighted Average Grant Date Fair Value
Geographical [Domain]
Geographical [Domain]
Entity Address, City or Town
Entity Address, City or Town
Cash flows from operating activities:
Cash Provided by (Used in) Operating Activity, Including Discontinued Operation [Abstract]
Andrew Guggenhime [Member]
Andrew Guggenhime
Effect of exchange rate changes on cash and cash equivalents
Effect of Exchange Rate on Cash, Cash Equivalent, Restricted Cash, and Restricted Cash Equivalent, Continuing Operation
Non-PEO NEO Average Compensation Actually Paid Amount
Non-PEO NEO Average Compensation Actually Paid Amount
Income Statement Location
Statement of Income Location, Balance [Domain]
Restricted Stock Units (RSUs)
Restricted stock units
Restricted Stock Units (RSUs) [Member]
Compensation Actually Paid vs. Other Measure
Compensation Actually Paid vs. Other Measure [Text Block]
Assets:
Assets, Fair Value Disclosure [Abstract]
Entity Emerging Growth Company
Entity Emerging Growth Company
Entity Common Stock, Shares Outstanding
Entity Common Stock, Shares Outstanding
Number of shares outstanding (in shares)
Beginning balance (in shares)
Ending balance (in shares)
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Number
Change in Fair Value as of Vesting Date of Prior Year Equity Awards Vested in Covered Year
Change in Fair Value as of Vesting Date of Prior Year Equity Awards Vested in Covered Year [Member]
Level 2
Fair Value, Inputs, Level 2 [Member]
2029
Other Commitment, to be Paid, Year Three
Insider Trading Policies and Procedures Not Adopted
Insider Trading Policies and Procedures Not Adopted [Text Block]
Common stock, shares outstanding (in shares)
Common Stock, Shares, Outstanding
Facility build out expenditures
Facility Build Out Expenditures
Facility Build Out Expenditures
Schedule of Information Related to Lease
Schedule Of Information Related To Right Of Use Assets And Lease Liabilities [Table Text Block]
Schedule of information related to right-of-use assets and lease liabilities.
Plan Name
Plan Name [Axis]
PEO
PEO [Member]
Remainder of 2026
Other Commitment, to be Paid, Remainder of Fiscal Year
Lease Contractual Term [Domain]
Lease Contractual Term [Domain]
Fair value assets transferred into level 3
Fair Value, Measurement with Unobservable Inputs Reconciliation, Recurring Basis, Asset Transfers Into Level 3
Schedule of Contractual Maturities of Investments
Investments Classified by Contractual Maturity Date [Table Text Block]
Interest income
Investment Income, Interest
2014 Plan, 2020 Plan and 2020 ESPP
Two Thousand Fourteen Equity Incentive Plan And Two Thousand Twenty Equity Incentive Plan And Two Thousand Twenty Employee Stock Purchase Plan [Member]
Two thousand fourteen equity incentive plan and two thousand twenty equity incentive plan and two thousand twenty employee stock purchase plan.
UNITED STATES
UNITED STATES
Funding Arrangement [Table]
Funding Arrangement [Table]
Funding arrangement.
Dividends or Other Earnings Paid on Equity Awards not Otherwise Reflected in Total Compensation for Covered Year
Dividends or Other Earnings Paid on Equity Awards not Otherwise Reflected in Total Compensation for Covered Year [Member]
Funding Arrangement [Line Items]
Funding Arrangement [Line Items]
Funding arrangement.
Total assets measured at fair value, fair value
Cash And Cash Equivalents And Investments
Cash and cash equivalents and investments.
Accumulated Deficit
Retained Earnings [Member]
Cost Reimbursement Sub-Award Agreement
Cost Reimbursement Sub Award Agreement [Member]
Cost reimbursement sub-award agreement.
Prepaid expenses and other current assets
Prepaid Expense and Other Assets, Current
Number of Shares
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Number of Shares [Roll Forward]
Entity Address, Postal Zip Code
Entity Address, Postal Zip Code
Restatement Determination Date
Restatement Determination Date
Share-Based Payment Arrangement [Abstract]
Share-Based Payment Arrangement [Abstract]
Cash, cash equivalents and restricted cash, beginning of period
Cash, cash equivalents and restricted cash, end of period
Cash, cash equivalents and restricted cash
Cash, Cash Equivalent, Restricted Cash, and Restricted Cash Equivalent, Continuing Operation
Income Statement [Abstract]
Income Statement [Abstract]
Tax provision
Income Tax Expense (Benefit)
Investments in fair market value, continuous unrealized loss position for more than 12 months
Debt Securities, Available-for-Sale, Continuous Unrealized Loss Position, 12 Months or Longer
Sale of Stock
Sale of Stock [Domain]
Preferred stock, shares issued (in shares)
Preferred Stock, Shares Issued
Pension Adjustments Service Cost
Pension Adjustments Service Cost [Member]
Investments:
Debt Securities, Available-for-Sale [Abstract]
Fair Value Hierarchy and NAV
Fair Value Hierarchy and NAV [Axis]
2020 Equity Incentive Plan
Two Thousand Twenty Equity Incentive Plan [Member]
Two thousand twenty equity incentive plan.
Net loss
Net Income (Loss), Including Portion Attributable to Noncontrolling Interest
Restatement does not require Recovery
Restatement Does Not Require Recovery [Text Block]
Organization, Consolidation and Presentation of Financial Statements [Abstract]
Organization, Consolidation and Presentation of Financial Statements [Abstract]
Purchases of manufacturing facility build-out and equipment construction-in-progress
Payments to Acquire Manufacturing Facility and Equipment
Payments to Acquire Manufacturing Facility and Equipment
Amortization of operating lease right-of-use assets
Operating Lease, Right-of-Use Asset, Periodic Reduction
Compensation Actually Paid vs. Company Selected Measure
Compensation Actually Paid vs. Company Selected Measure [Text Block]
Thereafter
Other Commitment, To Be Paid, After Year Four
Other Commitment, To Be Paid, After Year Four
City Area Code
City Area Code
Award Timing, How MNPI Considered
Award Timing, How MNPI Considered [Text Block]
Follow on public offering
Follow On Public Offering [Member]
Follow on public offering member.
All Trading Arrangements
All Trading Arrangements [Member]
Equity Awards Adjustments, Footnote
Equity Awards Adjustments, Footnote [Text Block]
Total Shareholder Return Vs Peer Group
Total Shareholder Return Vs Peer Group [Text Block]
Weighted-Average Remaining Contractual Term (Years), Vested and expected to vest
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Outstanding, Weighted Average Remaining Contractual Term
Accrued expenses
Accrued Liabilities, Current
Share-based compensation arrangement by share-based payment award, equity instruments other than options, non vested, number (in shares)
Beginning balance (in shares)
Ending balance (in shares)
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Number
Commitments and Contingencies Disclosure [Abstract]
Commitments and Contingencies Disclosure [Abstract]
Cash flows from investing activities:
Cash Provided by (Used in) Investing Activity, Including Discontinued Operation [Abstract]
General and administrative
General and Administrative Expense
Upfront consideration
Upfront Consideration
Upfront consideration.
Pay vs Performance Disclosure
Pay vs Performance Disclosure [Table]
Net cash used in operating activities
Cash Provided by (Used in) Operating Activity, Including Discontinued Operation
Long-term investments
Long-Term Investments
Agreement initial term
Agreement Initial Term
Agreement Initial Term
Sales of investments
Proceeds from Sale of Debt Securities, Available-for-Sale
Preferred stock, par value (in dollars per share)
Preferred Stock, Par or Stated Value Per Share
Schedule of Estimated Fair Value of Employee Stock Options
Schedule of Share-Based Payment Award, Stock Options, Valuation Assumptions [Table Text Block]
Options and RSUs granted (in shares)
Share-Based Compensation Arrangement by Share-Based Payment Award, Number of Shares Granted
Share-Based Compensation Arrangement by Share-Based Payment Award, Number of Shares Granted
Equity Valuation Assumption Difference, Footnote
Equity Valuation Assumption Difference, Footnote [Text Block]
PEO Total Compensation Amount
PEO Total Compensation Amount
Weighted-Average Exercise Price Per Share, Vested and expected to vest (in dollars per share)
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Outstanding, Weighted Average Exercise Price
Money market funds
Money Market Funds [Member]
Lease Contractual Term [Axis]
Lease Contractual Term [Axis]
Equity Components
Equity Components [Axis]
Assumed lease rental payment
Assumed Lease Rental Payment
Assumed lease rental payment.
Non-Rule 10b5-1 Arrangement Adopted
Non-Rule 10b5-1 Arrangement Adopted [Flag]
2027
Other Commitment, to be Paid, Year One
Number of reportable segments
Number of Reportable Segments
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions and Methodology [Abstract]
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions and Methodology [Abstract]
ATM sales agreement at weighted average price (in usd per share)
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Grants in Period, Intrinsic Value, Amount Per Share
Unaudited Interim Condensed Consolidated Financial Statements
Unaudited Interim Condensed Financial Statements [Policy Text Block]
Unaudited interim condensed financial statements policy.
Supply Commitment [Table]
Supply Commitment [Table]
Amortized Cost
Debt Securities, Available-for-Sale, Amortized Cost
Other Performance Measure, Amount
Other Performance Measure, Amount
Weighted- Average Exercise Price Per Share
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Exercise Price [Abstract]
Additional milestone payments in cash
Additional Milestone Payments in Cash
Additional milestone payments in cash.
Entity Address, State or Province
Entity Address, State or Province
Schedule Of Antidilutive Securities Excluded From Computation Of Earnings Per Share [Table]
Antidilutive Security, Excluded EPS Calculation [Table]
Pre-funded warrants of common stock shares outstanding immediately after effect to the exercise (in percentage)
Pre-funded Warrants of Common Stock Shares Outstanding Immediately After Effect to the Exercise
Pre-funded warrants of common stock shares outstanding immediately after effect to the exercise.
Total current liabilities
Liabilities, Current
Potential funding committed by award
Potential Funding Committed By Award
Potential funding committed by award.
Over Allotment Option
Over-Allotment Option [Member]
Operating Leased Assets [Line Items]
Operating Leased Assets [Line Items]
Individual:
Individual [Axis]
Restricted cash
Restricted Cash
Thereafter
Lessee, Operating Lease, Liability, to be Paid, after Year Four
Lessee, Operating Lease, Liability, to be Paid, after Year Four
Research and development
Research and Development Expense [Member]
Additional paid-in capital
Additional Paid in Capital, Common Stock
Net cash provided by (used in) investing activities
Cash Provided by (Used in) Investing Activity, Including Discontinued Operation
Aggregate Change in Present Value of Accumulated Benefit for All Pension Plans Reported in Summary Compensation Table
Aggregate Change in Present Value of Accumulated Benefit for All Pension Plans Reported in Summary Compensation Table [Member]
Document Fiscal Year Focus
Document Fiscal Year Focus
Basis of Presentation and Principles of Consolidation
Basis of Accounting, Policy [Policy Text Block]
Operating lease right-of-use assets
Operating Lease, Right-of-Use Asset
Forgone Recovery, Explanation of Impracticability
Forgone Recovery, Explanation of Impracticability [Text Block]
Entity Interactive Data Current
Entity Interactive Data Current
Weighted- Average Remaining Contractual Term (Years)
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Additional Disclosures [Abstract]
Plan Name
Plan Name [Domain]
Unrecognized share-based compensation expense, expected weighted-average period (in years)
Share-Based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Period for Recognition
Options exercised (in shares)
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercises in Period
Equity [Abstract]
Equity [Abstract]
Aggregate Intrinsic Value, Exercisable
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Intrinsic Value
Segment Reporting
Segment Reporting Disclosure [Text Block]
Schedule of Long-Term Purchase Commitment
Long-Term Purchase Commitment [Table Text Block]
U.S. Treasury securities
US Treasury Securities [Member]
Long-Lived Tangible Asset
Long-Lived Tangible Asset [Axis]
Other Commitments [Line Items]
Other Commitments [Line Items]
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Sutro Biopharma Inc
Sutro Biopharma Inc [Member]
Sutro Biopharma, Inc.
Compensation Actually Paid vs. Total Shareholder Return
Compensation Actually Paid vs. Total Shareholder Return [Text Block]
Shares forfeited (in shares)
Share-Based Compensation Arrangement by Share-Based Payment Award, Number of Shares Forfeited
Share-Based Compensation Arrangement by Share-Based Payment Award, Number of Shares Forfeited
Total assets measured at fair value, gross unrealized losses
Cash And Cash Equivalents And Investments Gross Unrealized Loss Before Tax
Cash and cash equivalents and investments gross unrealized loss before tax.
Depreciation and amortization
Depreciation, Depletion and Amortization
Other assets
Other Assets, Noncurrent
Entity Central Index Key
Entity Central Index Key
PEO Name
PEO Name
Sale of stock, consideration received on transaction
Sale of Stock, Consideration Received on Transaction
Prior Year End Fair Value of Equity Awards Granted in Any Prior Year that Fail to Meet Applicable Vesting Conditions During Covered Year
Prior Year End Fair Value of Equity Awards Granted in Any Prior Year that Fail to Meet Applicable Vesting Conditions During Covered Year [Member]
Outstanding Aggregate Erroneous Compensation Amount
Outstanding Aggregate Erroneous Compensation Amount
Unrealized foreign exchange loss (gain)
Unrealized Gain (Loss), Foreign Currency Transaction, after Tax
Arrangement Duration
Trading Arrangement Duration
Schedule of Segment Reporting Information, by Segment [Table]
Schedule of Segment Reporting Information, by Segment [Table]
Expected volatility, Maximum
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Volatility Rate, Maximum
Segments [Axis]
Segments [Axis]
Prepaid expenses and other current assets
Increase (Decrease) in Prepaid Expense and Other Assets
Exercise Price
Award Exercise Price
Entity Filer Category
Entity Filer Category
Local Phone Number
Local Phone Number
Additional 402(v) Disclosure
Additional 402(v) Disclosure [Text Block]
Collaborative Arrangement and Arrangement Other than Collaborative
Collaborative Arrangement and Arrangement Other than Collaborative [Domain]
Equity Incentive Plans
Share-Based Payment Arrangement [Text Block]
Assets
Assets [Abstract]
Underlying Security Market Price Change
Underlying Security Market Price Change, Percent
Cancelled (in dollars per share)
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Forfeitures, Weighted Average Grant Date Fair Value
Fair Value Measurements and Fair Value of Financial Instruments
Fair Value Disclosures [Text Block]
Operating lease right-of-use assets
Increase (Decrease) In Operating Lease Right Of Use Asset
Increase (Decrease) In Operating Lease Right Of Use Asset
Stockholders' Equity
Equity, Attributable to Parent [Abstract]
Vesting Date Fair Value of Equity Awards Granted and Vested in Covered Year
Vesting Date Fair Value of Equity Awards Granted and Vested in Covered Year [Member]
Lessee, operating lease, extended term of contract (in months)
Lessee, Operating Lease, Extended Term of Contract
Lessee, Operating Lease, Extended Term of Contract
Entity Address, Address Line One
Entity Address, Address Line One
Entity Address, Address Line Two
Entity Address, Address Line Two
2014 Equity Incentive Plan
Two Thousand Fourteen Equity Incentive Plan [Member]
Two thousand fourteen equity incentive plan.
Research and development
Research and Development Expense
Accumulated Other Comprehensive Gain (Loss)
AOCI Attributable to Parent [Member]
Number of renewal options
Number Of Renewal Options
Number of renewal options.
Shares withheld for taxes (in shares)
Share-Based Payment Arrangement, Shares Withheld for Tax Withholding Obligation
Operating lease liabilities — long-term
Operating Lease, Liability, Noncurrent
Capital expenditure related to the facility build out and equipment
Capital Expenditure Related To The Facility Build Out And Equipment
Capital Expenditure Related To The Facility Build Out And Equipment
Operating lease, rent adjustment(in percentage)
Operating Lease, Rent Adjustment Percentage
Operating Lease, Rent Adjustment Percentage
Fair Value as of Grant Date
Award Grant Date Fair Value
Entity Registrant Name
Entity Registrant Name
Stock Price or TSR Estimation Method
Stock Price or TSR Estimation Method [Text Block]
Granted (in shares)
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Grants in Period
Cancelled (in shares)
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Forfeited in Period
Unrecognized stock-based compensation expense
Share-Based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Amount
Document Quarterly Report
Document Quarterly Report
Investments in fair market value, continuous unrealized loss position, less than 12 months
Debt Securities, Available-for-Sale, Continuous Unrealized Loss Position, Less than 12 Months
Issuance costs
Adjustments to Additional Paid in Capital, Stock Issued, Issuance Costs
Changed Peer Group, Footnote
Changed Peer Group, Footnote [Text Block]
Counterparty Name
Counterparty Name [Domain]
Number of operating segments
Number of Operating Segments
2028
Lessee, Operating Lease, Liability, to be Paid, Year Two
Repurposing fee, credit duration
Repurposing Fee, Credit Duration
Repurposing Fee, Credit Duration
Beginning balance
Ending balance
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Aggregate Intrinsic Value, Outstanding
Net accretion of discounts on investments
Accretion (Amortization) of Discounts and Premiums, Investments
Adjustment To PEO Compensation, Footnote
Adjustment To PEO Compensation, Footnote [Text Block]
Weighted-Average Remaining Contractual Term (Years)
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Remaining Contractual Term
Granted (in dollars per share)
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Grants in Period, Weighted Average Grant Date Fair Value
Title
Trading Arrangement, Individual Title
Peer Group Total Shareholder Return Amount
Peer Group Total Shareholder Return Amount
Underwritten Public Offering
Underwritten Public Offering [Member]
Underwritten Public Offering
Pre -funded warrant exercised (in shares)
Class Of Warrant Or Right Number Of Securities Called By Each Warrant Or Right Exercised
Class of warrant or right number of securities called by each warrant or right exercised.
Collaborative Arrangement and Arrangement Other than Collaborative
Collaborative Arrangement and Arrangement Other than Collaborative [Axis]
Restatement Determination Date:
Restatement Determination Date [Axis]
Non-PEO NEO
Non-PEO NEO [Member]
Aggregate Intrinsic Value
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Intrinsic Value
Issuance of common stock in connection with employee incentive plans
Stock Issued During Period, Value, Employee Stock Purchase Plan
Sublease Agreement
Sublease Agreement [Member]
Sublease Agreement
National Institutes Of Health
National Institutes Of Health [Member]
National Institutes Of Health
Sale of Stock
Sale of Stock [Axis]
Gross Unrealized Gains
Debt Securities, Available-for-Sale, Accumulated Gross Unrealized Gain, before Tax
Name
Trading Arrangement, Individual Name
All Award Types
Award Type [Domain]
Funding Arrangement [Abstract]
Funding Arrangement [Abstract]
Funding arrangement.
2027
Lessee, Operating Lease, Liability, to be Paid, Year One
Equity Awards Adjustments
Equity Awards Adjustments [Member]
Pension Benefits Adjustments, Footnote
Pension Benefits Adjustments, Footnote [Text Block]
Compensation Amount
Outstanding Recovery Compensation Amount
Schedule of Capital Leased Assets [Table]
Schedule of Capital Leased Assets [Table]
SWITZERLAND
SWITZERLAND
Schedule of Share-Based Payment Arrangement, Activity
Share-Based Payment Arrangement, Activity [Table Text Block]
Statement of Comprehensive Income [Abstract]
Statement of Comprehensive Income [Abstract]
Accrued contract manufacturing expenses
Accrued Contract Manufacturing Expenses
Accrued contract manufacturing expenses.
Certificate of Deposits
Certificates of Deposit [Member]
Recovery of Erroneously Awarded Compensation Disclosure [Line Items]
Grant Pickering [Member]
Grant Pickering
MNPI Disclosure Timed for Compensation Value
MNPI Disclosure Timed for Compensation Value [Flag]
Name
Awards Close in Time to MNPI Disclosures, Individual Name
Beginning balance (in dollars per share)
Ending balance (in dollars per share)
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Weighted Average Grant Date Fair Value
Restricted cash
Restricted Cash, Noncurrent
Fair value on date of settlement
Fair Value on Date of Settlement
Fair value on Date of Settlement.
Aggregate Erroneous Compensation Not Yet Determined
Aggregate Erroneous Compensation Not Yet Determined [Text Block]
Total non-cancelable purchase commitments due to our key manufacturing partners
Other Commitment
Employee Stock
Employee Stock [Member]
Commercial Manufacturing and Supply Agreements
Commitments Disclosure [Text Block]
Stock-based compensation expense
APIC, Share-Based Payment Arrangement, Increase for Cost Recognition
Total assets measured at fair value, gross unrealized gains
Cash And Cash Equivalents And Investments Gross Unrealized Gain Before Tax
Cash and cash equivalents and investments gross unrealized gain before tax.
Accumulated other comprehensive loss
Accumulated Other Comprehensive Income (Loss), Net of Tax
ATM Sales Agreement
A T M Sales Agreement [Member]
ATM sales agreement.
Aggregate Intrinsic Value, Vested and expected to vest
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Outstanding, Aggregate Intrinsic Value
Segments [Domain]
Segments [Domain]
Income Statement Location
Statement of Income Location, Balance [Axis]
Total noncurrent assets
Assets, Noncurrent
Aggregate Pension Adjustments Service Cost
Aggregate Pension Adjustments Service Cost [Member]
Research and development - internal costs
Internal Costs [Member]
Internal Costs
Fair Value Hierarchy and NAV
Fair Value Hierarchy and NAV [Domain]
Commercial paper
Commercial Paper, Not Included with Cash and Cash Equivalents [Member]
Class of warrant or right, number of securities called by warrants or rights (in shares)
Class of Warrant or Right, Number of Securities Called by Warrants or Rights
Minimum
Minimum
Minimum [Member]
Supply Commitment Arrangement [Domain]
Supply Commitment Arrangement [Domain]
Company Selected Measure Name
Company Selected Measure Name
Purchases of investments
Payments to Acquire Debt Securities, Available-for-Sale
Preferred stock, $0.001 par value — 10,000,000 shares authorized at March 31, 2026 and December 31, 2025; no shares issued and outstanding at March 31, 2026 and December 31, 2025
Preferred Stock, Value, Issued
Aggregate Available
Trading Arrangement, Securities Aggregate Available Amount
Accounts payable
Accounts Payable, Current
Cash paid for operating lease liabilities
Operating Lease, Payments
Proceeds from issuance of shares through employee equity incentive plans
Proceeds from Stock Plans
Stock Appreciation Rights (SARs)
Stock Appreciation Rights (SARs) [Member]
All Executive Categories
All Executive Categories [Member]
Common stock, $0.001 par value — 500,000,000 shares authorized at March 31, 2026 and December 31, 2025; 144,314,981 and 131,058,858 shares issued and outstanding at March 31, 2026 and December 31, 2025, respectively
Common stock, value, issued
Common Stock, Value, Issued
Expected volatility, Minimum
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Volatility Rate, Minimum
Short-term investments
Short-Term Investments
Commitments and Contingencies
Commitments and Contingencies Disclosure [Text Block]
Weighted-average shares outstanding, diluted (in shares)
Weighted-average shares outstanding used in computing net loss per share, diluted (in shares)
Weighted Average Number of Shares Outstanding, Diluted
Commitments and contingencies (Note 6)
Commitments and Contingencies
Changes in operating assets and liabilities:
Increase (Decrease) in Operating Liabilities [Abstract]
Non-GAAP Measure Description
Non-GAAP Measure Description [Text Block]
Weighted- Average Remaining Contractual Term
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Outstanding, Weighted Average Remaining Contractual Terms
Assignment Agreement
Assignment Agreement [Member]
Assignment Agreement.
Entity Small Business
Entity Small Business
Income Tax Disclosure [Abstract]
Income Tax Disclosure [Abstract]
Research and development - external costs
External Costs [Member]
External Costs
Preferred stock, shares outstanding (in shares)
Preferred Stock, Shares Outstanding
Document Transition Report
Document Transition Report
Upfront consideration in cash
Upfront Consideration in Cash
Upfront consideration in cash.
Due in one to five years
Debt Securities, Available-for-Sale, Fair Value, Maturity, Allocated and Single Maturity Date, after Year One Through Five
Underlying Securities
Award Underlying Securities Amount
Equity Component
Equity Component [Domain]
Document Period End Date
Document Period End Date
PEO Actually Paid Compensation Amount
PEO Actually Paid Compensation Amount
Jefferies LLC
Jefferies Limited Liability Company [Member]
Jefferies limited liability company.
Income Taxes
Income Tax Disclosure [Text Block]
Awards Close in Time to MNPI Disclosures, Table
Awards Close in Time to MNPI Disclosures [Table Text Block]
Investments in fair market value, continuous unrealized loss position, less than 12 months and 12 months or longer
Debt Securities, Available-for-Sale, Continuous Unrealized Loss Position, Less Than 12 Months and 12 Months or Longer
Debt Securities, Available-for-Sale, Continuous Unrealized Loss Position, Less Than 12 Months and 12 Months or Longer
Weighted-Average Remaining Contractual Term (Years), Exercisable
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Weighted Average Remaining Contractual Term
Operating lease liabilities
Increase (Decrease) in Operating Lease Liability
Document Type
Document Type
Level 3
Fair Value, Inputs, Level 3 [Member]
Net Loss Per Share
Earnings Per Share [Text Block]
Name
Outstanding Recovery, Individual Name
Proceeds from issuance of common stock
Proceeds from Issuance of Common Stock
All Individuals
All Individuals [Member]
Fair Value Disclosures [Abstract]
Fair Value Disclosures [Abstract]
Purchases of property and equipment
Payments to Acquire Property, Plant, and Equipment
Vested and expected options (in shares)
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Outstanding, Number
Name
Forgone Recovery, Individual Name
Total current assets
Assets, Current
Reportable Segment
Reportable Segment [Member]
Reportable Segment
Statistical Measurement
Statistical Measurement [Axis]
Year-over-Year Change in Fair Value of Equity Awards Granted in Prior Years That are Outstanding and Unvested
Year-over-Year Change in Fair Value of Equity Awards Granted in Prior Years That are Outstanding and Unvested [Member]
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis Valuation Techniques [Line Items]
Fair Value Measurement Inputs and Valuation Techniques [Line Items]
Aggregate Erroneous Compensation Amount
Aggregate Erroneous Compensation Amount
Number of conditional options
Number of Conditional Options
Number of Conditional Options
Intrinsic value of the stock options exercised
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercises in Period, Intrinsic Value
Taxes paid related to the net share settlement of equity awards
Payment, Tax Withholding, Share-Based Payment Arrangement
Peer Group Issuers, Footnote
Peer Group Issuers, Footnote [Text Block]
Net loss (in thousands)
Net Income (Loss) Available to Common Stockholders, Basic
Erroneous Compensation Analysis
Erroneous Compensation Analysis [Text Block]
Aggregate Intrinsic Value
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Aggregate Intrinsic Value [Abstract]
Other comprehensive (loss) gain
Other Comprehensive Income (Loss), Net of Tax, Portion Attributable to Parent
Current liabilities:
Liabilities, Current [Abstract]
Weighted-Average Remaining Contractual Term (Years) and Aggregate Instrinsic Value
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Additional Disclosures [Abstract]
Geographical [Axis]
Geographical [Axis]
Additional renewal period
Number of Additional Renewal Periods
Number of additional renewal periods.
Total operating expenses
Operating Expenses
Rule 10b5-1 Arrangement Terminated
Rule 10b5-1 Arrangement Terminated [Flag]
Risk-free interest rate, Minimum
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Risk Free Interest Rate, Minimum
Level 1
Fair Value, Inputs, Level 1 [Member]
Funding Arrangements
Funding Arrangement [Text Block]
Funding arrangement.
Beginning balance (in shares)
Ending balance (in shares)
Shares, Outstanding
Accrued expenses
Increase (Decrease) in Accrued Liabilities
Exercise of stock options (in shares)
Number Of Options Exercised Excludes Options Exercised From NPLN
Number of options exercised, excludes options exercised from NPLN.
Net loss per share, diluted (in dollars per share)
Earnings Per Share, Diluted
Erroneously Awarded Compensation Recovery
Erroneously Awarded Compensation Recovery [Table]
Title of 12(b) Security
Title of 12(b) Security
Supplemental disclosure of non-cash investing and financing activities:
Cash Flow, Noncash Investing and Financing Activities Disclosure [Abstract]
Other comprehensive loss:
Other Comprehensive Income (Loss), Net of Tax, Portion Attributable to Parent [Abstract]
Sale of stock, number of shares issued in transaction (in shares)
Sale of Stock, Number of Shares Issued in Transaction
Debt Securities, Available-for-Sale, Unrealized Loss Position, Fair Value [Table]
Debt Securities, Available-for-Sale, Unrealized Loss Position, Fair Value [Table]
Potential funding period of award to develop vaccine to prevent infections (in years)
Potential Funding Period Of Award To Develop Vaccine To Prevent Infections
Potential funding period of award to develop vaccine to prevent infections.
Earnings Per Share [Abstract]
Earnings Per Share [Abstract]
Total other income, net
Total other income, net
Nonoperating Income (Expense)
Debt Securities, Available-for-Sale, Unrealized Loss Position [Line Items]
Debt Securities, Available-for-Sale, Unrealized Loss Position [Line Items]
Schedule of Potentially Dilutive Securities Excluded From Computation of Diluted Net Loss Per Share
Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table Text Block]
Less: Imputed interest
Lessee, Operating Lease, Liability, Undiscounted Excess Amount
options exercised (in dollars per share)
Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Exercises in Period, Weighted Average Exercise Price
Available for issuance of shares increased (in shares)
Share Based Compensation Arrangement By Share Based Payment Award Number Of Shares Increase In Available For Grant
Share based compensation arrangement by share based payment award number of shares increase in available for grant.
Schedule of Stock Unit Award Activity PSU
Nonvested Restricted Stock Shares Activity [Table Text Block]
Award Timing Disclosures [Line Items]
Options granted (in dollars per share)
Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Grants in Period, Weighted Average Exercise Price
Measurement Frequency
Measurement Frequency [Domain]
Accrued compensation
Employee-related Liabilities, Current
Total future undiscounted lease payments
Lessee, Operating Lease, Liability, to be Paid
Operating lease, renewal term (in months)
Lessee, Operating Lease, Renewal Term
Lonza Commercial Manufacturing and Supply Agreement
Lonza Commercial Manufacturing and Supply Agreement [Member]
Lonza commercial manufacturing and supply agreement.
Stockholders' Equity
Equity [Text Block]
Gross Unrealized Losses
Cash And Cash Equivalents Gross Unrealized Loss Before Tax
Cash and cash equivalents gross unrealized loss before tax.
Net loss
Net loss
Net loss
Net loss
Net Income (Loss) Attributable to Parent
Expiration Date
Trading Arrangement Expiration Date
Property and equipment, net
Property, Plant and Equipment, Net
Segment Reporting Information [Line Items]
Segment Reporting Information [Line Items]
Preferred stock, shares authorized (in shares)
Preferred Stock, Shares Authorized
Adoption Date
Trading Arrangement Adoption Date
Compensation Actually Paid vs. Net Income
Compensation Actually Paid vs. Net Income [Text Block]
Entity Current Reporting Status
Entity Current Reporting Status
Operating lease, agreement term (in years)
Lessee, Operating Lease, Term of Contract
Awards Close in Time to MNPI Disclosures
Awards Close in Time to MNPI Disclosures [Table]
Loss from operations
Operating Income (Loss)
Accumulated deficit
Retained Earnings (Accumulated Deficit)
Schedule of Stock-based Compensation Expense
Share-Based Payment Arrangement, Cost by Plan [Table Text Block]
Statement of Financial Position [Abstract]
Statement of Financial Position [Abstract]
Year-end Fair Value of Equity Awards Granted in Covered Year that are Outstanding and Unvested
Year-end Fair Value of Equity Awards Granted in Covered Year that are Outstanding and Unvested [Member]
Executive Category:
Executive Category [Axis]
Agreement termination penalty
Agreement Termination Penalty
Agreement termination penalty.
Current Fiscal Year End Date
Current Fiscal Year End Date
Expected term (in years)
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Term
Aggregate Grant Date Fair Value of Equity Award Amounts Reported in Summary Compensation Table
Aggregate Grant Date Fair Value of Equity Award Amounts Reported in Summary Compensation Table [Member]
Automatic renewal period
Automatic Renewal Period
Automatic renewal period.
Weighted- Average Grant-Date Fair Value Per Share
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Weighted Average Grant Date Fair Value [Abstract]
Performance Contingent Stock Options (PCSOs)
Performance Contingent Stock Options (PCSOs) [Member]
Performance Contingent Stock Options (PCSOs)
Number of shares available for grant (in shares)
Beginning balance (in shares)
Ending balance (in shares)
Share-Based Compensation Arrangement by Share-Based Payment Award, Number of Shares Available for Grant
Statement [Table]
Statement [Table]
Other income (expense)
Other Nonoperating Income (Expense)
Adjustments to reconcile net loss to net cash used in operating activities:
Adjustment to Reconcile Net Income to Cash Provided by (Used in) Operating Activity [Abstract]
Cash flows from financing activities:
Cash Provided by (Used in) Financing Activity, Including Discontinued Operation [Abstract]
Weighted-average grant date fair value of options granted (in dollars per share)
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Grants in Period, Weighted Average Grant Date Fair Value
Cash
Cash [Member]
Equity Awards Adjustments, Excluding Value Reported in Compensation Table
Equity Awards Adjustments, Excluding Value Reported in the Compensation Table [Member]
Employee stock purchase plan
Employee Stock Purchase Plan [Member]
Employee stock purchase plan.
2020 Employee Stock Purchase Plan
Two Thousand Twenty Employee Stock Purchase Plan [Member]
Two thousand twenty employee stock purchase plan.
Company Organization and Nature of Business
Organization, Consolidation and Presentation of Financial Statements Disclosure [Text Block]
Cash and cash equivalents:
Cash and Cash Equivalents [Abstract]
Antidilutive securities excluded from computation of diluted net loss per share (in shares)
Antidilutive Securities Excluded from Computation of Earnings Per Share, Amount
Supply Commitment [Line Items]
Supply Commitment [Line Items]
All Adjustments to Compensation
All Adjustments to Compensation [Member]
Amendment Flag
Amendment Flag
Average price (in dollars per share)
Sale of Stock, Price Per Share
Other Commitments [Table]
Other Commitments [Table]
Leases
Lessee, Operating Leases [Text Block]
Termination Date
Trading Arrangement Termination Date
Potential funding amount of award to develop vaccine to prevent infections
Potential Funding Amount Of Award To Develop Vaccine To Prevent Infections
Potential funding amount of award to develop vaccine to prevent infections.
Net cash provided by financing activities
Cash Provided by (Used in) Financing Activity, Including Discontinued Operation
Insider Trading Policies and Procedures Adopted
Insider Trading Policies and Procedures Adopted [Flag]
Measure:
Measure [Axis]
Weighted-average discount rate
Operating Lease, Weighted Average Discount Rate, Percent
Schedule of Activity Under Stock Option Plans
Share-Based Payment Arrangement, Option, Activity [Table Text Block]
Basis of Presentation and Summary of Significant Accounting Policies
Basis of Presentation and Significant Accounting Policies [Text Block]
Long-Lived Tangible Asset
Long-Lived Tangible Asset [Domain]
Schedule of Financial Instruments Measured at Fair Value on Recurring Basis
Fair Value, Assets Measured on Recurring Basis [Table Text Block]
Weighted-average shares outstanding, basic (in shares)
Weighted-average shares outstanding used in computing net loss per share, basic (in shares)
Weighted Average Number of Shares Outstanding, Basic
Grant receivable on unreimbursed, eligible costs incurred
Grants Receivable
Schedule of Computation of Basic and Diluted Net Loss Per Share
Schedule of Earnings Per Share, Basic and Diluted [Table Text Block]
Options exercisable (in shares)
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Number
Segment Reporting [Abstract]
Pay vs Performance Disclosure, Table
Pay vs Performance [Table Text Block]
Operating lease rent expense recognized
Operating Lease, Expense
Forgone Recovery due to Violation of Home Country Law, Amount
Forgone Recovery due to Violation of Home Country Law, Amount
Entity Tax Identification Number
Entity Tax Identification Number
Unrealized (losses) gains on investments, net
OCI, Debt Securities, Available-for-Sale, Unrealized Holding Gain (Loss), before Adjustment and Tax
Beginning balance (in dollars per share)
Ending balance (in dollars per share)
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Exercise Price
Aggregate gross proceeds from issuance of common stock
Gross Proceeds From Issuance Of Common Stock
Gross proceeds from issuance of common stock.
Upfront consideration in cash after agreement date
Upfront Consideration in Cash After Agreement Date
Upfront consideration in cash after agreement date.
Forgone Recovery due to Expense of Enforcement, Amount
Forgone Recovery due to Expense of Enforcement, Amount
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]
Common stock, par value (in dollars per share)
Common Stock, Par or Stated Value Per Share
Common stock, shares issued (in shares)
Common Stock, Shares, Issued
2020 Plan
2020 Plan [Member]
2020 Plan
Weighted-average remaining lease term (in years)
Operating Lease, Weighted Average Remaining Lease Term
Options granted (in shares)
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Grants in Period, Gross
Gross Unrealized Gains
Cash And Cash Equivalents Gross Unrealized Gain Before Tax
Cash and cash equivalents gross unrealized gain before tax.
Use of Estimates
Use of Estimates, Policy [Policy Text Block]
Trading Arrangement:
Trading Arrangement [Axis]
Total Shareholder Return Amount
Total Shareholder Return Amount
Foreign currency translation adjustments, net
Other Comprehensive Income (Loss), Foreign Currency Transaction and Translation Adjustment, Net of Tax
Shares Of Common Stock Held By Mr. Pickering [Member]
Shares Of Common Stock Held By Mr. Pickering
Insider Trading Arrangements [Line Items]
Security Exchange Name
Security Exchange Name
Options forfeited (in dollars per share)
Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Forfeitures in Period, Weighted Average Exercise Price
Total liabilities
Liabilities
Antidilutive Securities, Name
Antidilutive Securities, Name [Domain]
Purchases of property and equipment recorded in accounts payable and accrued expenses
Capital Expenditures Incurred but Not yet Paid
Pension Adjustments Prior Service Cost
Pension Adjustments Prior Service Cost [Member]
Operating expenses:
Operating Expenses [Abstract]
Material Terms of Trading Arrangement
Material Terms of Trading Arrangement [Text Block]
Repurposing fee
Repurposing Fee
Repurposing fee
Unvested PSUs
Phantom Share Units (PSUs) [Member]
Leerink Partners LLC
Leerink Partners LLC [Member]
Leerink Partners LLC
Asset Class
Asset Class [Domain]
Issuance of common stock and pre-funded warrants in connection with follow-on public offering, net of commissions and offering expenses
Stock Issued During Period, Value, New Issues
Statement [Line Items]
Statement [Line Items]
Asset-backed securities
Asset-Backed Securities [Member]
Rule 10b5-1 Arrangement Adopted
Rule 10b5-1 Arrangement Adopted [Flag]
Cash and cash equivalents
Cash and Cash Equivalent
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis Valuation Techniques [Table]
Fair Value Measurement Inputs and Valuation Techniques [Table]
Counterparty Name
Counterparty Name [Axis]
Shares authorized (in shares)
Share-Based Compensation Arrangement by Share-Based Payment Award, Number of Additional Shares Authorized
Risk-free interest rate, Maximum
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Risk Free Interest Rate, Maximum
Common Stock
Common Stock [Member]
Vested and released (in shares)
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Vested in Period
Fair Value
Total
Debt Securities, Available-for-Sale
Entity Incorporation, State or Country Code
Entity Incorporation, State or Country Code
Non-NEOs
Non-NEOs [Member]
Corporate debt
Corporate Debt Securities [Member]
Net increase (decrease) in cash, cash equivalents and restricted cash
Cash, Cash Equivalent, Restricted Cash, and Restricted Cash Equivalent, Period Increase (Decrease), Including Exchange Rate Effect and Discontinued Operation