Equity Incentive Plans (Tables)
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3 Months Ended |
Mar. 31, 2026 |
| Share-Based Payment Arrangement [Abstract] |
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| Schedule of Activity Under Stock Option Plans |
Stock option activity under our 2020 Plan, including performance contingent stock options (“PCSOs”), and 2014 Plan, which excludes options to purchase 29,638 shares granted outside of the 2020 Plan and 2014 Plan, was as follows: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | Options Outstanding | | PCSOs Outstanding | | | | | (in thousands, except share and per share data) | | | Number of Options | | Weighted- Average Exercise Price Per Share | | Weighted- Average Remaining Contractual Term (Years) | | Aggregate Intrinsic Value | | Number of Options | | Weighted- Average Exercise Price Per Share | | Weighted- Average Remaining Contractual Term (Years) | | Aggregate Intrinsic Value | | Balances — December 31, 2025 | | 10,960,801 | | $ | 43.64 | | | 7.16 | | $ | 130,351 | | | 621,860 | | | $ | 102.70 | | | 8.85 | | $ | — | | | Options granted | | 974,819 | | | 59.64 | | | | | | | | | | | | | | | Options exercised | | (366,253) | | | 25.00 | | | | | | | | | | | | | | | Options forfeited | | (39,336) | | | 68.78 | | | | | | | (6,600) | | | $ | 102.70 | | | | | | | Balances — March 31, 2026 | | 11,530,031 | | | $ | 45.50 | | | 7.25 | | $ | 207,917 | | | 615,260 | | | $ | 102.70 | | | 8.60 | | $ | — | | | Vested and expected to vest — March 31, 2026 | | 11,530,031 | | | $ | 45.50 | | | 7.25 | | $ | 207,917 | | | 615,260 | | | $ | 102.70 | | | 8.60 | | $ | — | | | Exercisable at March 31, 2026 | | 6,934,265 | | $ | 36.99 | | | 6.27 | | $ | 170,485 | | | — | | | | | | | $ | — | |
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| Schedule of Stock Unit Award Activity PSU |
Stock unit award activity, including performance based stock units (“PSUs”), for the three months ended March 31, 2026 was as follows: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | Unvested RSUs | | Unvested PSUs | | | (in thousands, except share and per share data) | | | Number of Shares | | Weighted- Average Grant-Date Fair Value Per Share | | Weighted- Average Remaining Contractual Term (Years) | | Aggregate Intrinsic Value | | Number of Shares | | Weighted- Average Grant-Date Fair Value Per Share | | Weighted- Average Remaining Contractual Term (Years) | | Aggregate Intrinsic Value | | Unvested at December 31, 2025 | | 2,340,589 | | $ | 54.55 | | | 1.42 | | $ | 107,995 | | | 175,513 | | | $ | 151.48 | | | 2.85 | | $ | 8,098 | | | Granted | | 914,574 | | 59.94 | | | | | | | — | | | | | | | | | Vested and released | | (396,884) | | 52.91 | | | | | | | — | | | | | | | | | Cancelled | | (30,247) | | 51.18 | | | | | | | — | | | | | | | | | Unvested at March 31, 2026 | | 2,828,032 | | $ | 56.56 | | | 1.54 | | $ | 164,337 | | | 175,513 | | $ | 151.48 | | | 2.61 | | $ | 10,199 | |
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| Schedule of Share-Based Payment Arrangement, Activity |
Shares available for grant under our 2020 Plan for the three months ended March 31, 2026 were as follows: | | | | | | | | | | | Number of Shares | | Balance — December 31, 2025 | | 8,821,691 | | Shares authorized | | 6,552,942 | | Options and RSUs granted | | (1,889,393) | | | Shares forfeited | | 76,183 | | Shares withheld for taxes | | 157,014 | | Balance — March 31, 2026 | | 13,718,437 |
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| Schedule of Estimated Fair Value of Employee Stock Options |
The following assumptions were used in the Black-Scholes options pricing model for stock options granted in the respective period of: | | | | | | | | | | | | | Three Months Ended March 31, | | 2026 | | 2025 | | Expected volatility | 65.6% - 66.6% | | 67.3% - 67.5% | | Expected term (in years) | 5.4 | | 5.2 - 5.3 | | Risk-free interest rate | 3.6% - 3.8% | | 4.1% - 4.5% |
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| Schedule of Stock-based Compensation Expense |
We recorded total stock-based compensation expense for the three months ended March 31, 2026 and 2025 related to the 2014 Plan, the 2020 Plan and the 2020 ESPP in the condensed consolidated statements of operations and allocated the amounts as follows: | | | | | | | | | | | | | Three Months Ended March 31, | | 2026 | | 2025 | | (in thousands) | | Research and development | $ | 20,678 | | | $ | 15,925 | | | General and administrative | 17,286 | | | 14,690 | | | Total stock-based compensation expense | $ | 37,964 | | | $ | 30,615 | |
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