Summary of Significant Accounting Policies Significant Accounting Policies [Text Block] Statistical Measurement [Domain] Statistical Measurement [Domain] Award Timing Predetermined Award Timing Predetermined [Flag] 2026 Lessee, Operating Lease, Liability, to be Paid, Remainder of Fiscal Year Entity File Number Entity File Number Additional Paid-in Capital Additional Paid-in Capital [Member] Maturity in Years Cash And Cash Equivalents, Term Cash And Cash Equivalents, Term Tabular List, Table Tabular List [Table Text Block] Recently Issued Accounting Pronouncements Not Yet Adopted New Accounting Pronouncements, Policy [Policy Text Block] Accounts payable Increase (Decrease) in Accounts Payable PIPE-307 PIPE-307 [Member] In relation to the product PIPE-307. Unrealized Losses Cash Equivalents, Accumulated Gross Unrealized Loss, Before Tax Cash Equivalents, Accumulated Gross Unrealized Loss, Before Tax Unrealized Losses Debt Securities, Available-for-Sale, Accumulated Gross Unrealized Loss, before Tax Trading Arrangements, by Individual Trading Arrangements, by Individual [Table] Net loss per share, basic (in dollars per share) Earnings Per Share, Basic Adjustment to Compensation: Adjustment to Compensation [Axis] Named Executive Officers, Footnote Named Executive Officers, Footnote [Text Block] Common stock reserved for future issuance (in shares) Total common stock reserved for future issuance (in shares) Common Stock, Capital Shares Reserved for Future Issuance Accrued Expenses Accrued Expenses [Text Block] The entire disclosure for accrued expenses. Stock, Class of Stock [Table] Stock, Class of Stock [Table] Schedule of Segment Reporting Information, by Segment Schedule of Segment Reporting Information, by Segment [Table Text Block] Schedule of Amortized Cost and Fair Value of the Company’s Cash Equivalents and Marketable Securities by Major Investment Category Schedule of Available-for-Sale Securities Reconciliation [Table Text Block] Adjustment to Compensation, Amount Adjustment to Compensation Amount Stock-based compensation Share-Based Payment Arrangement, Noncash Expense Common stock options Share-Based Payment Arrangement, Option [Member] Award Timing MNPI Disclosure Award Timing MNPI Disclosure [Text Block] Antidilutive Securities [Axis] Antidilutive Securities [Axis] Total stockholders' equity Beginning balance Ending balance Equity, Attributable to Parent Debt Securities, Available-for-Sale [Table] Debt Securities, Available-for-Sale [Table] Insider Trading Policies and Procedures [Line Items] Share-based payment arrangement, expense Share-Based Payment Arrangement, Expense Common stock, shares authorized (in shares) Common Stock, Shares Authorized Stock issued during period, shares (in shares) Stock Issued During Period, Shares, New Issues Current assets: Assets, Current [Abstract] Options cancelled and forfeited (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Forfeitures in Period Total liabilities and stockholders' equity Liabilities and Equity Schedule of Common Stock Reserved for Future Issuance Schedule of Common Stock Reserved for Future Issuance [Table Text Block] Tabular disclosure of common stock reserved for future issuance. Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items] Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items] Options Outstanding Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding [Roll Forward] Cash and cash equivalents at beginning of period Cash and cash equivalents at end of period Cash, Cash Equivalent, Restricted Cash, and Restricted Cash Equivalent, Including Discontinued Operation Liabilities and Stockholders' Equity Liabilities and Equity [Abstract] Cover [Abstract] Cover [Abstract] Cash equivalents Cash and Cash Equivalents, Fair Value Disclosure Maximum Maximum [Member] General and administrative General and Administrative Expense [Member] Options exercisable (in dollars per share) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Weighted Average Exercise Price Accounting Policies [Abstract] Accounting Policies [Abstract] Fair Value Debt Securities, Available-for-Sale, Unrealized Loss Position Schedule of Lessee, Operating Lease, Liability, Future Minimum Lease Payments Lessee, Operating Lease, Liability, to be Paid, Maturity [Table Text Block] Non-PEO NEO Average Total Compensation Amount Non-PEO NEO Average Total Compensation Amount Schedule of Share-Based Compensation Arrangements by Share-Based Payment Award [Table] Schedule of Share-Based Compensation Arrangements by Share-Based Payment Award [Table] Adjustment to Non-PEO NEO Compensation Footnote Adjustment to Non-PEO NEO Compensation Footnote [Text Block] Pay vs Performance Disclosure [Line Items] Class of Warrant or Right [Axis] Class of Warrant or Right [Axis] Operating lease, liability Total lease liability obligations Operating Lease, Liability U.S. Government agency securities US Government Agencies Debt Securities [Member] Forgone Recovery due to Disqualification of Tax Benefits, Amount Forgone Recovery due to Disqualification of Tax Benefits, Amount Non-Rule 10b5-1 Arrangement Terminated Non-Rule 10b5-1 Arrangement Terminated [Flag] Entity Shell Company Entity Shell Company Statement of Stockholders' Equity [Abstract] Statement of Stockholders' Equity [Abstract] Accrued research and development expenses Accrued Research and Development Expenses Amount of accrued research and development expenses, classified as current. Statement of Cash Flows [Abstract] Statement of Cash Flows [Abstract] Company Selected Measure Amount Company Selected Measure Amount 2029 Lessee, Operating Lease, Liability, to be Paid, Year Three Award Timing MNPI Considered Award Timing MNPI Considered [Flag] Comprehensive loss Comprehensive Income (Loss), Net of Tax, Attributable to Parent Options expired (in dollars per share) Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Expirations in Period, Weighted Average Exercise Price Name Measure Name Schedule of Share-Based Payment Arrangement, Expensed and Capitalized, Amount Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Table Text Block] Accretion of premiums/discounts on marketable securities, net Investment Income, Net, Amortization of Discount and Premium Current portion of operating lease liabilities Less: Current portion of operating lease liabilities Operating Lease, Liability, Current Class of Stock [Line Items] Class of Stock [Line Items] Document Fiscal Period Focus Document Fiscal Period Focus Award Timing Method Award Timing Method [Text Block] Award Type [Axis] Award Type [Axis] Total assets Assets Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] Trading Symbol Trading Symbol Entity Address, City or Town Entity Address, City or Town Gains Cash And Cash Equivalents And Debt Securities, Available-For-Sale, Accumulated Gross Unrealized Gain, Before Tax Cash And Cash Equivalents And Debt Securities, Available-For-Sale, Accumulated Gross Unrealized Gain, Before Tax Operating activities Cash Provided by (Used in) Operating Activity, Including Discontinued Operation [Abstract] Weighted-average discount rate Finance Lease, Weighted Average Discount Rate, Percent Gain on marketable securities Marketable Security, Gain (Loss) Other segment items Segment Reporting, Other Segment Item, Amount Non-PEO NEO Average Compensation Actually Paid Amount Non-PEO NEO Average Compensation Actually Paid Amount Statement of Income Location, Balance [Domain] Statement of Income Location, Balance [Domain] Compensation Actually Paid vs. Other Measure Compensation Actually Paid vs. Other Measure [Text Block] Entity Emerging Growth Company Entity Emerging Growth Company Entity Common Stock, Shares Outstanding Entity Common Stock, Shares Outstanding General Atomics Court Lease General Atomics Court Lease [Member] General Atomics Court Lease Debt Securities, Available-for-Sale [Line Items] Debt Securities, Available-for-Sale [Line Items] Beginning balance (in shares) Ending balance (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Number Change in Fair Value as of Vesting Date of Prior Year Equity Awards Vested in Covered Year Change in Fair Value as of Vesting Date of Prior Year Equity Awards Vested in Covered Year [Member] Significant Other Observable Inputs (Level 2) Fair Value, Inputs, Level 2 [Member] Insider Trading Policies and Procedures Not Adopted Insider Trading Policies and Procedures Not Adopted [Text Block] Common stock, shares, outstanding (in shares) Common Stock, Shares, Outstanding Fair Value, Net Derivative Asset (Liability) Measured on Recurring Basis, Unobservable Input Reconciliation [Table] Fair Value, Net Derivative Asset (Liability) Measured on Recurring Basis, Unobservable Input Reconciliation [Table] Plan Name [Axis] Plan Name [Axis] PEO PEO [Member] Lease Contractual Term [Domain] Lease Contractual Term [Domain] Schedule of Common Stock Outstanding Roll Forward Schedule of Common Stock Outstanding Roll Forward [Table Text Block] Interest income Investment Income, Interest Changes in operating assets and liabilities Adjustment to Reconcile Net Income to Cash Provided by (Used in) Operating Activity, Increase (Decrease) in Operating Capital [Abstract] Exercise of stock options Stock Issued During Period, Value, Stock Options Exercised Dividends or Other Earnings Paid on Equity Awards not Otherwise Reflected in Total Compensation for Covered Year Dividends or Other Earnings Paid on Equity Awards not Otherwise Reflected in Total Compensation for Covered Year [Member] Expected volatility Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Volatility Rate Accumulated Deficit Retained Earnings [Member] Prepaid expenses and other current assets Prepaid Expense and Other Assets, Current Schedule of Accrued Expenses Schedule of Accrued Liabilities [Table Text Block] Entity Address, Postal Zip Code Entity Address, Postal Zip Code Restatement Determination Date Restatement Determination Date Income Statement [Abstract] Income Statement [Abstract] Purchases of marketable securities Payments to Acquire Marketable Securities Class B Common Class B [Member] Sale of Stock [Domain] Sale of Stock [Domain] Yankee debt Yankee Debt [Member] Yankee Debt Shares available for issuance under the 2024 Equity Incentive Plan The 2024 Equity Incentive Plan [Member] Represents the 2024 Equity Incentive Plan. 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Number of reportable segments Number of Reportable Segments Options expired (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Expirations in Period Amortized Cost Debt Securities, Available-for-Sale, Amortized Cost Other Performance Measure, Amount Other Performance Measure, Amount Weighted- Average Exercise Price Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Exercise Price [Abstract] Fair Value Cash Equivalent, Unrealized Loss Position Cash Equivalent, Unrealized Loss Position Entity Address, State or Province Entity Address, State or Province Antidilutive Security, Excluded EPS Calculation [Table] Antidilutive Security, Excluded EPS Calculation [Table] Fair Value Measurements Fair Value Measurement, Policy [Policy Text Block] Total current liabilities Liabilities, Current Individual: Individual [Axis] Research and development Research and Development Expense [Member] Entities [Table] Entities [Table] Net cash provided by (used in) investing activities Cash Provided by (Used in) Investing Activity, Including Discontinued Operation Aggregate Change in Present Value of Accumulated Benefit for All Pension Plans Reported in Summary Compensation Table Aggregate Change in Present Value of Accumulated Benefit for All Pension Plans Reported in Summary Compensation Table [Member] Common stock reserved under the 2024 Employee Stock Purchase Plan 2024 Employee Stock Purchase Plan (the "2024 ESPP") [Member] Represents the 2024 Employee Stock Purchase Plan (the "2024 ESPP"). Document Fiscal Year Focus Document Fiscal Year Focus Basis of Presentation Basis of Accounting, Policy [Policy Text Block] Stockholders’ Equity Shareholders' Equity and Share-Based Payments [Text Block] Operating lease right-of-use assets Operating Lease, Right-of-Use Asset Forgone Recovery, Explanation of Impracticability Forgone Recovery, Explanation of Impracticability [Text Block] Entity Interactive Data Current Entity Interactive Data Current Plan Name [Domain] Plan Name [Domain] Weighted-average period (in years) Share-Based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Period for Recognition Exercise of stock options (in shares) Options exercised (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercises in Period Equity [Abstract] Options exercisable Aggregate Intrinsic Value Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Intrinsic Value Significant segment expenses Segment Reconciliation [Abstract] Segment Reporting Segment Reporting Disclosure [Text Block] Increase (Decrease) in Stockholders' Equity [Roll Forward] Increase (Decrease) in Stockholders' Equity [Roll Forward] Compensation Actually Paid vs. Total Shareholder Return Compensation Actually Paid vs. Total Shareholder Return [Text Block] Unrealized Losses Cash Equivalent, Unrealized Loss Position, Accumulated Loss Cash Equivalent, Unrealized Loss Position, Accumulated Loss Depreciation and amortization Depreciation, Depletion and Amortization Other long-term assets Other Assets, Noncurrent Entity Central Index Key Entity Central Index Key PEO Name PEO Name Consideration received on transaction Sale of Stock, Consideration Received on Transaction Prior Year End Fair Value of Equity Awards Granted in Any Prior Year that Fail to Meet Applicable Vesting Conditions During Covered Year Prior Year End Fair Value of Equity Awards Granted in Any Prior Year that Fail to Meet Applicable Vesting Conditions During Covered Year [Member] Outstanding Aggregate Erroneous Compensation Amount Outstanding Aggregate Erroneous Compensation Amount Arrangement Duration Trading Arrangement Duration Schedule of Segment Reporting Information, by Segment [Table] Schedule of Segment Reporting Information, by Segment [Table] Payments of deferred offering costs Payment of Financing and Stock Issuance Costs Segments [Axis] Segments [Axis] Prepaid expenses and other current assets Increase (Decrease) in Prepaid Expense and Other Assets Exercise Price Award Exercise Price Entity Filer Category Entity Filer Category Local Phone Number Local Phone Number Class of Stock [Domain] Class of Stock [Domain] Additional 402(v) Disclosure Additional 402(v) Disclosure [Text Block] Collaborative Arrangement and Arrangement Other than Collaborative [Domain] Collaborative Arrangement and Arrangement Other than Collaborative [Domain] Assets Assets [Abstract] Underlying Security Market Price Change Underlying Security Market Price Change, Percent Class of Warrant or Right [Domain] Class of Warrant or Right [Domain] Fair Value Measurements Fair Value Disclosures [Text Block] Stockholders' equity: Equity, Attributable to Parent [Abstract] Vesting Date Fair Value of Equity Awards Granted and Vested in Covered Year Vesting Date Fair Value of Equity Awards Granted and Vested in Covered Year [Member] Entity Address, Address Line One Entity Address, Address Line One Research and development Research and Development Expense Accumulated Other Comprehensive Income (Loss) AOCI Attributable to Parent [Member] Operating lease liabilities, net of current portion Operating lease liabilities, net of current portion Operating Lease, Liability, Noncurrent Conversion of Class B common stock into Class A common stock (in shares) Stock Issued During Period, Shares, Conversion of Convertible Securities Amortized Cost Cash, Cash Equivalents And Available-For-Sale Debt Securities, Amortized Cost Cash, Cash Equivalents And Available-For-Sale Debt Securities, Amortized Cost Fair Value as of Grant Date Award Grant Date Fair Value Entity Registrant Name Entity Registrant Name Nature of Expense [Axis] Nature of Expense [Axis] Stock Price or TSR Estimation Method Stock Price or TSR Estimation Method [Text Block] Total unrecognized stock-based compensation Share-Based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Amount Common stock, number of votes Common Stock, Number of Votes Number of votes for holders of common stock. Document Quarterly Report Document Quarterly Report Total financial assets Assets, Fair Value Disclosure Debt securities, available-for-sale, unrealized loss position, number of positions Debt Securities, Available-for-Sale, Unrealized Loss Position, Number of Positions Changed Peer Group, Footnote Changed Peer Group, Footnote [Text Block] 2028 Lessee, Operating Lease, Liability, to be Paid, Year Two Adjustment To PEO Compensation, Footnote Adjustment To PEO Compensation, Footnote [Text Block] Outstanding Weighted-Average Remaining Contractual Term Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Remaining Contractual Term Title Trading Arrangement, Individual Title Peer Group Total Shareholder Return Amount Peer Group Total Shareholder Return Amount Collaborative Arrangement and Arrangement Other than Collaborative [Axis] Collaborative Arrangement and Arrangement Other than Collaborative [Axis] Restatement Determination Date: Restatement Determination Date [Axis] Non-PEO NEO Non-PEO NEO [Member] Outstanding Aggregate Intrinsic Value Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Intrinsic Value Sale of Stock [Axis] Sale of Stock [Axis] Unrealized Gain Cash Equivalents, Accumulated Gross Unrealized Gain, Before Tax Cash Equivalents, Accumulated Gross Unrealized Gain, Before Tax Unrealized Gains Debt Securities, Available-for-Sale, Accumulated Gross Unrealized Gain, before Tax Name Trading Arrangement, Individual Name Award Type [Domain] Award Type [Domain] 2027 Lessee, Operating Lease, Liability, to be Paid, Year One Equity Awards Adjustments Equity Awards Adjustments [Member] Pension Benefits Adjustments, Footnote Pension Benefits Adjustments, Footnote [Text Block] Compensation Amount Outstanding Recovery Compensation Amount Follow-on Offering Follow-on Offering [Member] Follow-on Offering J&J License Agreement J&J License Agreement [Member] Represents the J&J License Agreement. Dividend yield Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Dividend Rate Certificates of deposits Certificates of Deposit [Member] Recovery of Erroneously Awarded Compensation Disclosure [Line Items] Losses Cash And Cash Equivalents And Debt Securities, Available-For-Sale, Accumulated Gross Unrealized Loss, Before Tax Cash And Cash Equivalents And Debt Securities, Available-For-Sale, Accumulated Gross Unrealized Loss, Before Tax MNPI Disclosure Timed for Compensation Value MNPI Disclosure Timed for Compensation Value [Flag] Name Awards Close in Time to MNPI Disclosures, Individual Name Aggregate Erroneous Compensation Not Yet Determined Aggregate Erroneous Compensation Not Yet Determined [Text Block] Amortized Cost Cash Equivalents, at Carrying Value Stock-based compensation APIC, Share-Based Payment Arrangement, Increase for Cost Recognition Common stock warrant Common Stock Warrant [Member] Represents common stock warrant. Accumulated other comprehensive income (loss) Accumulated Other Comprehensive Income (Loss), Net of Tax Shares available for issuance under the 2026 Inducement Plan 2026 Inducement Plan [Member] 2026 Inducement Plan Options vested and expected to vest Aggregate Intrinsic Value Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Outstanding, Aggregate Intrinsic Value Financial Instruments [Domain] Financial Instruments [Domain] Segments [Domain] Segments [Domain] Statement of Income Location, Balance [Axis] Statement of Income Location, Balance [Axis] Aggregate Pension Adjustments Service Cost Aggregate Pension Adjustments Service Cost [Member] Fair Value Hierarchy and NAV [Domain] Fair Value Hierarchy and NAV [Domain] Commercial paper Commercial Paper, Not Included with Cash and Cash Equivalents [Member] Company Selected Measure Name Company Selected Measure Name Preferred stock, $0.001 par value; authorized shares—10,000,000 at March 31, 2026 and December 31, 2025; no shares issued or outstanding at March 31, 2026 and December 31, 2025. Preferred Stock, Value, Issued Aggregate Available Trading Arrangement, Securities Aggregate Available Amount Accounts payable Accounts Payable, Current Cash paid for amounts included in the measurement of lease liabilities Operating Lease, Payments Stock Appreciation Rights (SARs) Stock Appreciation Rights (SARs) [Member] All Executive Categories All Executive Categories [Member] Common stock Common Stock, Value, Issued Commitments and Contingencies Commitments and Contingencies Disclosure [Text Block] Weighted-average shares of common shares outstanding, diluted (in shares) Weighted Average Number of Shares Outstanding, Diluted Commitments and contingencies (Note 8) Commitments and Contingencies Non-GAAP Measure Description Non-GAAP Measure Description [Text Block] Entity Small Business Entity Small Business Employee Stock Ownership Plan (ESOP), Plan [Domain] Employee Stock Ownership Plan (ESOP), Plan [Domain] Marketable Securities [Abstract] Preferred stock, shares outstanding (in shares) Preferred Stock, Shares Outstanding Document Transition Report Document Transition Report Short-Term Investments Short-Term Investments [Member] Underlying Securities Award Underlying Securities Amount PIPE-791 PIPE-791 [Member] In relation to the product PIPE-791. Upfront payment received Upfront Payment Received Amount of upfront payment received. Equity Component [Domain] Equity Component [Domain] Document Period End Date Document Period End Date Fair Value, Net Derivative Asset (Liability) Measured on Recurring Basis, Unobservable Input Reconciliation [Line Items] Fair Value, Net Derivative Asset (Liability) Measured on Recurring Basis, Unobservable Input Reconciliation [Line Items] PEO Actually Paid Compensation Amount PEO Actually Paid Compensation Amount Cash and Cash Equivalents [Domain] Cash and Cash Equivalents [Domain] Cash Equivalents and Marketable Securities Cash, Cash Equivalent, and Marketable Security [Text Block] Class A Common Class A [Member] Awards Close in Time to MNPI Disclosures, Table Awards Close in Time to MNPI Disclosures [Table Text Block] Options exercisable Weighted-Average Remaining Contractual Term Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Weighted Average Remaining Contractual Term Operating lease liabilities Increase (Decrease) in Operating Lease Liability Document Type Document Type Significant Unobservable Inputs (Level 3) Fair Value, Inputs, Level 3 [Member] Net Loss Per Share Earnings Per Share [Text Block] Name Outstanding Recovery, Individual Name Loss Contingencies [Table] Loss Contingencies [Table] Additional paid-in-capital Additional Paid in Capital Product and Service [Axis] Product and Service [Axis] All Individuals All Individuals [Member] Reportable Segment Reportable Segment [Member] Reportable Segment Fair Value Disclosures [Abstract] Purchase of property and equipment Payments to Acquire Property, Plant, and Equipment Options vested and expected to vest (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Outstanding, Number Name Forgone Recovery, Individual Name Total current assets Assets, Current Statistical Measurement [Axis] Statistical Measurement [Axis] Year-over-Year Change in Fair Value of Equity Awards Granted in Prior Years That are Outstanding and Unvested Year-over-Year Change in Fair Value of Equity Awards Granted in Prior Years That are Outstanding and Unvested [Member] Employee Stock Ownership Plan (ESOP), Shares Contributed to ESOP (in shares) Employee Stock Ownership Plan (ESOP), Shares Contributed to ESOP Aggregate Erroneous Compensation Amount Aggregate Erroneous Compensation Amount Aggregate intrinsic value of options exercised Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercises in Period, Intrinsic Value Peer Group Issuers, Footnote Peer Group Issuers, Footnote [Text Block] Marketable securities Marketable Securities, Current Entity Information [Line Items] Entity Information [Line Items] Erroneous Compensation Analysis Erroneous Compensation Analysis [Text Block] Maturity in Years Debt Securities, Available-for-Sale, Term Current liabilities: Liabilities, Current [Abstract] Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Additional Disclosures [Abstract] Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Additional Disclosures [Abstract] Unallocated internal costs Unallocated Internal Costs [Member] In relation to unallocated internal costs. Lessee, Lease, Description [Line Items] Lessee, Lease, Description [Line Items] New Lease Agreement New Lease Agreement [Member] The new lease agreement. Total operating expenses Operating Expenses Rule 10b5-1 Arrangement Terminated Rule 10b5-1 Arrangement Terminated [Flag] Quoted Prices in Active Markets for Identical Assets (Level 1) Fair Value, Inputs, Level 1 [Member] Beginning balance (in shares) Ending balance (in shares) Shares, Outstanding Accrued expenses Increase (Decrease) in Accrued Liabilities Net loss per share, diluted (in dollars per share) Earnings Per Share, Diluted Erroneously Awarded Compensation Recovery Erroneously Awarded Compensation Recovery [Table] Title of 12(b) Security Title of 12(b) Security Lessee, Lease, Description [Table] Lessee, Lease, Description [Table] Other comprehensive income (loss): Other Comprehensive Income (Loss), Net of Tax, Portion Attributable to Parent [Abstract] Sale of stock, number of shares issued (in shares) Sale of Stock, Number of Shares Issued in Transaction Earnings Per Share [Abstract] Earnings Per Share [Abstract] Total other income, net Nonoperating Income (Expense) Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table Text Block] Loss on disposal of property and equipment Gain (Loss) On Disposal Of Property And Equipment The amount of gain (loss) on disposal of property and equipment. Less: Amount representing interest Lessee, Operating Lease, Liability, Undiscounted Excess Amount Options exercised (in dollars per share) Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Exercises in Period, Weighted Average Exercise Price Cash Equivalents Cash Equivalents [Member] Collaborative Arrangement and Arrangement Other than Collaborative [Table] Collaborative Arrangement and Arrangement Other than Collaborative [Table] Award Timing Disclosures [Line Items] Options granted (in dollars per share) Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Grants in Period, Weighted Average Exercise Price Accrued compensation expenses Employee-related Liabilities, Current Total minimum lease payments Lessee, Operating Lease, Liability, to be Paid Renewal term (in years) Lessee, Operating Lease, Renewal Term Unrealized gain (loss) on marketable securities Unrealized (loss) gain on marketable securities OCI, Debt Securities, Available-for-Sale, Unrealized Holding Gain (Loss), before Adjustment, after Tax CTX-343 CTX-343 [Member] In relation to CTX-343 Net loss Net loss Net loss Net loss Net Income (Loss) Attributable to Parent Schedule of Cash Equivalents And Debt Securities, Available-for-Sale, Unrealized Loss Position, Fair Value Debt Securities, Available-for-Sale, Unrealized Loss Position, Fair Value [Table Text Block] Expiration Date Trading Arrangement Expiration Date Other accrued expenses Other Accrued Liabilities, Current Yankee debt Debt Security, Government, Non-US [Member] Debt securities, available-for-sale, number of positions Debt Securities, Available-For-Sale, Number of Positions Number of investments in debt securities measured at fair value with change in fair value recognized in other comprehensive income (available-for-sale). Property and equipment, net Property, Plant and Equipment, Net Segment Reporting Information [Line Items] Segment Reporting Information [Line Items] Preferred stock, shares authorized (in shares) Preferred Stock, Shares Authorized Adoption Date Trading Arrangement Adoption Date Compensation Actually Paid vs. Net Income Compensation Actually Paid vs. Net Income [Text Block] Non-refundable, non-creditable milestone payments Contract with Customer, Asset, after Allowance for Credit Loss Entity Current Reporting Status Entity Current Reporting Status Lessee, operating lease, term of contract (in years) Lessee, Operating Lease, Term of Contract Awards Close in Time to MNPI Disclosures Awards Close in Time to MNPI Disclosures [Table] Loss from operations Loss from operations Operating Income (Loss) Accumulated deficit Accumulated deficit Retained Earnings (Accumulated Deficit) Financial Instrument [Axis] Financial Instrument [Axis] Adjustments to reconcile net loss to cash used in operating activities: Adjustment to Reconcile Net Income to Cash Provided by (Used in) Operating Activity, Noncash Item [Abstract] Statement of Financial Position [Abstract] Statement of Financial Position [Abstract] Year-end Fair Value of Equity Awards Granted in Covered Year that are Outstanding and Unvested Year-end Fair Value of Equity Awards Granted in Covered Year that are Outstanding and Unvested [Member] Executive Category: Executive Category [Axis] Current Fiscal Year End Date Current Fiscal Year End Date Class of Stock [Axis] Class of Stock [Axis] Expected term (in years) Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Term Aggregate Grant Date Fair Value of Equity Award Amounts Reported in Summary Compensation Table Aggregate Grant Date Fair Value of Equity Award Amounts Reported in Summary Compensation Table [Member] Other expense, net Other Nonoperating Income (Expense) Statement [Table] Statement [Table] License Agreement Collaborative Arrangement Disclosure [Text Block] Financing activities Cash Provided by (Used in) Financing Activity, Including Discontinued Operation [Abstract] Weighted-average grant-date fair value (in dollars per share) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Grants in Period, Weighted Average Grant Date Fair Value Equity Awards Adjustments, Excluding Value Reported in Compensation Table Equity Awards Adjustments, Excluding Value Reported in the Compensation Table [Member] Unrealized Losses Debt Securities, Available-for-Sale, Unrealized Loss Position, Accumulated Loss Schedule of Fair Value, Assets and Liabilities Measured on Recurring Basis Schedule of Fair Value, Assets and Liabilities Measured on Recurring Basis [Table Text Block] Sales and maturities of marketable securities Proceeds from Sale and Maturity of Marketable Securities Organization and Basis of Presentation Organization, Consolidation and Presentation of Financial Statements Disclosure [Text Block] Total potentially dilutive securities (in shares) Antidilutive Securities Excluded from Computation of Earnings Per Share, Amount All Adjustments to Compensation All Adjustments to Compensation [Member] Amendment Flag Amendment Flag Sale of stock, price per share (in dollars per share) Sale of Stock, Price Per Share Termination Date Trading Arrangement Termination Date Net cash provided by financing activities Cash Provided by (Used in) Financing Activity, Including Discontinued Operation Insider Trading Policies and Procedures Adopted Insider Trading Policies and Procedures Adopted [Flag] Accrued Liabilities [Abstract] Measure: Measure [Axis] Schedule of Stock Option Activity Share-Based Payment Arrangement, Option, Activity [Table Text Block] At The Market Offering At The Market Offering [Member] Represents an at the market offering. Weighted-average shares of common shares outstanding, basic (in shares) Weighted Average Number of Shares Outstanding, Basic Options exercisable (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Number Segment Reporting [Abstract] Pay vs Performance Disclosure, Table Pay vs Performance [Table Text Block] Operating lease expenses Operating Lease, Expense Forgone Recovery due to Violation of Home Country Law, Amount Forgone Recovery due to Violation of Home Country Law, Amount Risk free interest rate Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Risk Free Interest Rate Other income (expense): Nonoperating Income (Expense) [Abstract] Entity Tax Identification Number Entity Tax Identification Number Employee Stock Ownership Plan (ESOP) Name [Axis] Employee Stock Ownership Plan (ESOP) Name [Axis] Beginning balance (in dollars per share) Ending balance (in dollars per share) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Exercise Price Forgone Recovery due to Expense of Enforcement, Amount Forgone Recovery due to Expense of Enforcement, Amount Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items] Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items] Common stock, par value (in dollars per share) Common Stock, Par or Stated Value Per Share Common stock, shares, issued (in shares) Common Stock, Shares, Issued Weighted-average remaining lease term Operating Lease, Weighted Average Remaining Lease Term Options granted (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Grants in Period, Gross Use of Estimates Use of Estimates, Policy [Policy Text Block] Trading Arrangement: Trading Arrangement [Axis] Total Shareholder Return Amount Total Shareholder Return Amount Loss Contingencies [Line Items] Loss Contingencies [Line Items] Insider Trading Arrangements [Line Items] Security Exchange Name Security Exchange Name Options cancelled and forfeited (in dollars per share) Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Forfeitures in Period, Weighted Average Exercise Price Interim Period, Costs Not Allocable [Domain] Interim Period, Costs Not Allocable [Domain] Total liabilities Liabilities Antidilutive Securities, Name [Domain] Antidilutive Securities, Name [Domain] Cash and Cash Equivalents [Axis] Cash and Cash Equivalents [Axis] Pension Adjustments Prior Service Cost Pension Adjustments Prior Service Cost [Member] Operating expenses: Operating Expenses [Abstract] Material Terms of Trading Arrangement Material Terms of Trading Arrangement [Text Block] Discovery programs Discovery Programs [Member] In relation to discovery programs. Statement [Line Items] Statement [Line Items] Asset-backed securities Asset-Backed Securities [Member] Rule 10b5-1 Arrangement Adopted Rule 10b5-1 Arrangement Adopted [Flag] Cash and cash equivalents Cash and Cash Equivalent Class A and Class B Common Stock Common Stock [Member] Fair Value Debt securities, fair value Debt Securities, Available-for-Sale Entity Incorporation, State or Country Code Entity Incorporation, State or Country Code Non-NEOs Non-NEOs [Member] Corporate debt securities Corporate Debt Securities [Member] Net increase (decrease) in cash and cash equivalents Cash, Cash Equivalent, Restricted Cash, and Restricted Cash Equivalent, Period Increase (Decrease), Including Exchange Rate Effect and Discontinued Operation Accrued professional and consulting expenses Accrued Professional Fees, Current