v3.26.1
Segment and Geographic Information
 3 Months Ended
Mar. 31, 2026
Segment Reporting [Abstract]  
Segment and Geographic Information Segment and Geographic Information
Operating segments are defined as components of an entity about which separate discrete information is available for evaluation by the chief operating decision maker, or decision-making group, in deciding how to allocate resources and in assessing performance. The Company currently operates in two business segments, which are U.S. and international segments for the development and commercialization of therapies for patients with rare diseases. A single management team that reports to the Chief Executive Officer comprehensively manages the entire business. The Company meets the aggregation criteria of ASC 280 and therefore has one reportable segment for the three months ended March 31, 2026 and March 31, 2025.
The table below is a summary of the segment profit or loss, including significant segment expenses (in thousands):
Three months ended March 31,
20262025
Net product revenue - U.S.$36,896 $24,369 
Net product revenue - International23,216 13,349 
Total net product revenue 60,112 37,718 
License revenue- (5,014)
Total revenue, net 60,112 32,704 
Cost of sales7,157 3,648 
Global headcount expense 58,653 34,868 
Preclinical, clinical and development expense 18,511 19,960 
Commercial & medical affairs 20,264 13,249 
Corporate, general & administrative 7,888 7,983 
Other income (expense), net(1,704)(644)
Interest income (expense), net(1,029)(1,770)
Income taxes 545 80 
Net loss $(55,639)$(49,498)
Geographic Data
The Company allocates, for the purpose of geographic data reporting, its revenue based upon the location of its customers. Total product revenue, net, by geographic area was as follows (in thousands):
Three months ended March 31,
20262025
US $36,896 $24,369 
International23,216 13,349 
Total product revenue, net$60,112 $37,718 
As of March 31, 2026 and December 31, 2025, long-lived assets at locations outside the United States were not material.