v3.26.1
CONDENSED CONSOLIDATED STATEMENTS OF INCOME (LOSS) - USD ($)
shares in Millions, $ in Millions
3 Months Ended
Mar. 31, 2026
Mar. 31, 2025
Revenues:    
Total revenues $ 1,068.9 $ 897.8
Operating expenses:    
Cost of product sales (excluding amortization of acquired developed technologies) 134.1 104.6
Selling, general and administrative 352.7 514.0
Research and development 196.0 180.7
Intangible asset amortization 172.3 154.4
Gain on sale of priority review voucher (122.8) 0.0
Total operating expenses 732.3 953.7
Income (loss) from operations 336.6 (55.9)
Interest expense, net (39.9) (53.7)
Foreign exchange gain (loss) 2.5 (0.2)
Income (loss) before income tax expense (benefit) and equity in loss of investees 299.2 (109.8)
Income tax expense (benefit) 6.1 (17.8)
Equity in loss of investees 0.0 0.5
Net income (loss) $ 293.1 $ (92.5)
Net income (loss) per ordinary share:    
Basic (in dollars per share) $ 4.73 $ (1.52)
Diluted (in dollars per share) $ 4.43 $ (1.52)
Weighted-average ordinary shares used in per share calculations - basic (in shares) 61.9 61.0
Weighted-average ordinary shares used in per share calculations - diluted (in shares) 66.1 61.0
Product sales, net    
Revenues:    
Total revenues $ 1,025.3 $ 839.4
Royalties and contract revenues    
Revenues:    
Total revenues $ 43.6 $ 58.4