| Certain Balance Sheet Items Property, plant and equipment consisted of the following (in millions): | | | | | | | | | | | | | March 31,
2026 | | December 31,
2025 | | Manufacturing equipment and machinery | $ | 92.9 | | | $ | 97.4 | | | Land and buildings | 71.8 | | | 72.2 | | | Computer software | 63.5 | | | 63.7 | | | Leasehold improvements | 63.6 | | | 63.6 | | | Construction-in-progress | 60.1 | | | 49.6 | | | Computer equipment | 22.5 | | | 21.9 | | | Furniture and fixtures | 10.4 | | | 10.0 | | | | | | | Subtotal | 384.8 | | | 378.4 | | | Less accumulated depreciation and amortization | (181.7) | | | (178.5) | | | Property, plant and equipment, net | $ | 203.1 | | | $ | 199.9 | |
Accrued liabilities consisted of the following (in millions): | | | | | | | | | | | | | March 31,
2026 | | December 31,
2025 | | Rebates and other sales deductions | $ | 484.3 | | | $ | 459.8 | | | Employee compensation and benefits | 182.2 | | | 215.4 | | | | | | | Inventory-related accruals | 57.3 | | | 34.0 | | | Accrued royalties | 47.6 | | | 47.1 | | | Clinical trial accruals | 38.2 | | | 42.0 | | | Sales return reserve | 26.6 | | | 26.4 | | | Consulting and professional services | 22.2 | | | 23.0 | | | Accrued development expenses | 21.6 | | | 24.4 | | | Accrued interest | 21.4 | | | 40.7 | | | Selling and marketing accruals | 21.4 | | | 15.4 | | | | | | | Current portion of lease liabilities | 14.9 | | | 14.7 | | | Accrued construction-in-progress | 9.6 | | | 14.3 | | | Derivative instrument liabilities | 8.5 | | | 4.2 | | | | | | | | | | | | | | | Other | 66.6 | | | 72.8 | | | Total accrued liabilities | $ | 1,022.4 | | | $ | 1,034.2 | |
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