75000 - Document - Cover Page
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75010 - Statement - Condensed Consolidated Balance Sheets (unaudited)
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75020 - Statement - Condensed Consolidated Balance Sheets (unaudited) (Parenthetical)
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75030 - Statement - Condensed Consolidated Statements of Operations and Comprehensive Loss
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75040 - Statement - Condensed Consolidated Statements of Changes in Stockholders' Equity
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75050 - Statement - Condensed Consolidated Statements of Changes in Stockholders' Equity (Parenthetical)
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75060 - Statement - Condensed Consolidated Statements of Cash Flows
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995455 - Disclosure - Organization, Description of Business and Liquidity
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995465 - Disclosure - Summary of Significant Accounting Policies
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995475 - Disclosure - Segment Reporting
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995485 - Disclosure - Reverse Merger
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995495 - Disclosure - Cash Equivalents and Marketable Securities
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995505 - Disclosure - Prepaid Expenses and Other Current Assets
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995515 - Disclosure - Property and Equipment
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995525 - Disclosure - Fair Value of Financial Instruments
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995535 - Disclosure - Accrued Expenses
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995545 - Disclosure - Restructuring and Other Charges
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995555 - Disclosure - Assets Sale
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995565 - Disclosure - Leases
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995575 - Disclosure - Stockholders' Equity
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995585 - Disclosure - Preferred Stock and Convertible Preferred Stock
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995595 - Disclosure - Stock-Based Compensation
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995605 - Disclosure - License Revenues
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995615 - Disclosure - Net Loss Per Share
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995625 - Disclosure - Commitments and Contingencies
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995635 - Disclosure - Summary of Significant Accounting Policies (Policies)
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995645 - Disclosure - Segment Reporting (Tables)
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995655 - Disclosure - Reverse Merger (Tables)
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995665 - Disclosure - Cash Equivalents and Marketable Securities (Tables)
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995675 - Disclosure - Prepaid Expenses and Other Current Assets (Tables)
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995685 - Disclosure - Property and Equipment (Tables)
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995695 - Disclosure - Fair Value of Financial Instruments (Tables)
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995705 - Disclosure - Accrued Expenses (Tables)
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995715 - Disclosure - Restructuring and Other Charges (Tables)
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995725 - Disclosure - Leases (Tables)
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995735 - Disclosure - Stockholders' Equity (Tables)
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995745 - Disclosure - Preferred Stock and Convertible Preferred Stock (Tables)
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995755 - Disclosure - Stock-Based Compensation (Tables)
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995765 - Disclosure - Net Loss Per Share (Tables)
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995775 - Disclosure - Organization, Description of Business and Liquidity - Additional Information (Detail)
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995785 - Disclosure - Segment Reporting - Additional Information (Detail)
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995795 - Disclosure - Segment Reporting - Schedule of Segment Profit or Loss, Including Significant Segment Expenses (Detail)
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995805 - Disclosure - Reverse Merger - Schedule of Company Obtained Assets and Liabilities (Detail)
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995815 - Disclosure - Cash Equivalents and Marketable Securities - Schedule of Fair Value of the Company's Cash Equivalents and Marketable Securities (Detail)
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995825 - Disclosure - Cash Equivalents and Marketable Securities - Schedule of Components of Interest Income (Detail)
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995835 - Disclosure - Prepaid Expenses and Other Current Assets - Summary of Prepaid Expenses and Other Current Assets (Detail)
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995845 - Disclosure - Property and Equipment - Schedule of Property and Equipment, Net (Detail)
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995855 - Disclosure - Property and Equipment - Additional Information (Detail)
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995865 - Disclosure - Fair Value of Financial Instruments - Schedule of Financial Assets Measured at Fair Value on Recurring Basis (Detail)
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995875 - Disclosure - Fair Value of Financial Instruments - Additional Information (Detail)
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995885 - Disclosure - Assets Sale (Additional Information) (Details)
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995895 - Disclosure - Accrued Expenses - Schedule of Accrued Expenses (Detail)
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995905 - Disclosure - Leases - Additional Information (Details)
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995915 - Disclosure - Leases - Summary of the Components of Lease Costs and Rent (Details)
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995925 - Disclosure - Leases - Schedule of Maturities of Operating Lease Liabilities (Details)
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995935 - Disclosure - Leases - Schedule of Maturities of Operating Lease Liabilities (Details) 2
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995945 - Disclosure - Leases - Schedule of Maturities of Operating Lease Liabilities (Details) 3
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995955 - Disclosure - Stockholders' Equity - Additional Information (Details)
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995965 - Disclosure - Stockholders' Equity - Schedule of Common Stock Reserved For Future Issuance (Details)
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995975 - Disclosure - Preferred Stock and Convertible Preferred Stock - Additional Information (Details)
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995985 - Disclosure - Restructuring and Other Charges (Additional Information) (Details)
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995995 - Disclosure - Restructuring and Other Charges - Summary of Restructuring Liability included in Accrued Payroll and Related Expenses (Details)
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996005 - Disclosure - Stock-Based Compensation - Additional Information (Detail)
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996015 - Disclosure - Stock-Based Compensation - Schedule of Stock Option Activity (Detail)
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996025 - Disclosure - Stock-Based Compensation - Schedule of Grant-date Fair Value of Stock Options Issued, Presented on a Weighted Average Basis (Detail)
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996035 - Disclosure - Stock-Based Compensation - Schedule of Stock Based Compensation Expense (Detail)
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996045 - Disclosure - License Revenues - Additional Information (Details)
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996055 - Disclosure - Net Loss Per Share - Schedule of Basic and diluted net loss per share of common stock (Detail)
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996065 - Disclosure - Net Loss Per Share - Additional Information (Details)
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996075 - Disclosure - Net Loss Per Share - Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share (Detail)
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996085 - Disclosure - Commitments and Contingencies - Additional Information (Details)
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996095 - Disclosure - Subsequent Events - Additional Information (Detail)
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The entire disclosure for assets held for sale.
Assets Held For Sale [Text Block]
Assets Sale
Entity Incorporation, State or Country Code
Entity incorporation state code
Preferred Stock, Shares Issued
Preferred stock, Shares issued
September Two Thousand Twenty Five Public Offering [Member]
September two thousand twenty five public offering.
September 2025 Public Offering [Member]
Plan Name [Axis]
Plan Name [Axis]
Research and Development Expense [Abstract]
Research and development expenses
Equity [Abstract]
Entity Current Reporting Status
Proceeds from Warrant Exercises
Proceeds from exercise of warrants and pre-funded warrants
U.S. Government Agency Securities
US Government Agencies Debt Securities [Member]
Operating Expenses [Abstract]
Operating expenses:
Fair Value, Inputs, Level 2 [Member]
Level 2
Commitments and Contingencies Disclosure [Text Block]
Commitments and Contingencies
Common Stock, Shares Authorized
Common stock, shares authorized
Convertible preferred stock, par value
Temporary Equity, Par or Stated Value Per Share
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Aggregate Intrinsic Value, Nonvested
Aggregate Intrinsic Value, Options unvested at March 31, 2026
Product and Service [Axis]
Product and Service [Axis]
Document Fiscal Period Focus
Revenues:
Revenue from Contract with Customer [Abstract]
Entity Shell Company
Convertible preferred stock, Shares Outstanding
Temporary Equity, Shares Outstanding
Other accrued expenses
Other Accrued Liabilities, Current
Accounts Payable And Accrued Expense [Abstract]
Accounts Payable And Accrued Expense [Abstract]
Cash and Cash Equivalent
Cash and cash equivalents
Cash and Cash Equivalents, at Carrying Value, Total
Upfront Payment [Member]
Upfront Payment [Member]
Upfront payment.
Common Stock, Shares, Issued
Common stock, Shares issued and sold
Common stock, Shares issued
Lessee, Operating Lease, Description
Operating lease description
Statement [Table]
Statement [Table]
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Grants in Period, Weighted Average Grant Date Fair Value
Weighted average fair value of stock options granted
Disclosure of License Revenue [Text Block]
Disclosure of License Revenue.
License Revenues
Share-Based Compensation Arrangement by Share-Based Payment Award, Purchase Price of Common Stock, Percent
Percentage of purchase price of common stock under the ESPP
Shares of common stock issued in pre-closing financing
Shares of Common Stock Issued in Pre Closing Financing
Shares of common stock issued in pre closing financing.
Statement [Line Items]
Statement [Line Items]
Business Combination [Domain]
Warrant [Member]
Warrant [Member]
Warrants for the purchase of common stock
Entity Filer Category
Liabilities and Equity
Total liabilities and stockholders' equity
Payables and Accruals [Abstract]
Payables and Accruals [Abstract]
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Weighted Average Exercise Price
Weighted-Average Exercise Price, Options exercisable as of March 31, 2026
Restructuring Type [Axis]
Long-Lived Tangible Asset [Axis]
Upfront and near-term milestone payments due
Upfront and Near Term Milestone Payments Due
Upfront and near term milestone payments due.
Shares pre-funded warrants to purchase
Shares Pre-Funded Warrants To Purchase
Shares pre-funded warrants to purchase
Restructuring and Related Costs [Table Text Block]
Summary of Restructuring Liability included in Accrued Payroll and Related Expenses
Cash and Cash Equivalents, Fair Value Disclosure
Fair Value, Cash and cash equivalents
Cash equivalents
Corporate debt securities
Amended Inducement Plan [Member]
Amended inducement plan member.
Amended Inducement Plan [Member]
Stock-based Compensation Expense
Investment Income, Interest
Interest income
Total interest and investment income
Debt Securities, Available-for-Sale, Noncurrent
Long-term investments
Prepaid Expenses and Other Current Assets
Other Current Assets [Text Block]
Reconciliation of Operating Profit (Loss) from Segments to Consolidated [Table Text Block]
Schedule of Segment Profit or Loss, Including Significant Segment Expenses
Personnel and Related Costs [Member]
Personnel and related costs.
Personnel and related costs [Member]
Discovery Expenses [Member]
Discovery expenses.
Discovery expenses [Member]
Additional paid-in capital
Additional Paid in Capital, Common Stock
Exercise Of Warrants And Pre-Funded Warrants Shares
Exercise of warrants and pre-funded warrants shares.
Related Party [Member]
Related Party [Member]
Former Related Party [Member]
Property, Plant and Equipment [Line Items]
Share-Based Compensation Arrangement by Share-Based Payment Award, Terms of Award
Share-based compensation arrangement by share-based payment award, terms of award
The amount of cash to be received as part of an asset purchase agreement.
Cash Consideration Asset Purchase Agreement
Cash Consideration
Igenica patent portfolio member
Igenica Patent Portfolio [Member]
Nonrelated Party [Member]
Non-related Party [Member]
Number of Shares, Granted
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Grants in Period, Gross
Share-based compensation arrangement by share-based payment award, options, grants in period, gross
Severance and related costs.
Severance and Related Costs [Member]
Severance and Related Costs [Member]
Schedule of Earnings Per Share, Basic and Diluted [Table Text Block]
Schedule of Basic and diluted net loss per share of common stock
Net loss per share attributable to common stockholders, basic
Earnings Per Share, Basic
Net loss per share, basic
Earnings Per Share, Basic, Total
Tenacia Biotechnology (Hong Kong) Co., Limited [Member]
Tenacia Biotechnology (Hong Kong) Co., Limited [Member]
Tenacia Biotechnology (Hong Kong) Co., Limited.
Number of Shares, Ending Balance
Number of Shares, Beginning Balance
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Number
Gain (Loss) on Disposition of Property Plant Equipment, Excluding Oil and Gas Property and Timber Property
Loss on disposal of property and equipment
Loss on disposal of property and equipment
Liabilities, Current
Total current liabilities
Accounts receivable, net
Increase (Decrease) in Accounts Receivable
Accounts receivable, net
Adjustment to Reconcile Net Income to Cash Provided by (Used in) Operating Activity [Abstract]
Adjustments to reconcile net loss to net cash used in operating activities:
Issuance of common stock upon exercise of warrants
Issuance of Common Stock Upon Exercise of Warrants
Issuance of common stock upon exercise of warrants
Holder Two [Member]
Holder two.
Proceeds from Sale and Maturity of Debt Securities, Available-for-Sale, Total
Proceeds from Sale and Maturity of Debt Securities, Available-for-Sale
Proceeds from sales and maturities of investment securities
Thereafter
Lessee, Operating Lease, Liability, to be Paid, after Year Four
Lessee operating lease liability to be paid after year four.
Aggregate Intrinsic Value, Granted
Share Based Compensation Arrangement By Share Based Payment Award Aggregate Intrinsic Value Granted
Share based compensation arrangement by share based payment award aggregate intrinsic value granted.
Restructuring and Related Cost, Number of Positions Eliminated, Period Percent
Reduction in workforce, Percent
Leads License Agreement [Member]
Leads license agreement.
Leads License Agreement [Member]
Stockholders' equity/(deficit):
Equity, Attributable to Parent [Abstract]
Entity Small Business
Retained Earnings (Accumulated Deficit)
Accumulated deficit
Retained Earnings (Accumulated Deficit), Total
Accumulated deficit
Other Commitments [Line Items]
Other Commitments [Line Items]
Holder One [Member]
Holder one.
Preferred Stock [Member]
Preferred Stock [Member]
Number of Shares, Forfeited
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Forfeitures in Period
Sale of Stock, Price Per Share
Stock issued, price per shares
Aggregate Intrinsic Value, Exercised
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercises in Period, Intrinsic Value
The amount of retention costs approved by the Company through specified dates as part of a corporate restructuring.
Restructuring Retention Costs Approved
Employee retention amount
Stock-Based Compensation
Share-Based Payment Arrangement [Text Block]
Organization, Consolidation and Presentation of Financial Statements [Abstract]
Leases.
Leases [Table]
Pre-funded Warrants Increase or Decrease Percentage
Pre-funded Warrants Increase or Decrease Percentage
Pre-funded warrants increase or decrease percentage
Claseprubart Program Related Expenses
Claseprubart program related expenses.
Total claseprubart program-related expenses
Leases [Abstract]
Upfront payments
Contract with Customer, Liability
Contract with Customer, Liability, Total
Upfront payments
Amendment Flag
Second Development Program [Member]
Second Development Program [Member]
Second development program member.
Product and Service [Domain]
Product and Service [Domain]
Pre-funded warrants total
Class of Warrant or Right, Number of Securities Called by Warrants or Rights
Pre-funded warrants to purchase
Shares purchased
Liabilities and Equity [Abstract]
Liabilities and Stockholders' Equity
Entity Address, Postal Zip Code
Cash Provided by (Used in) Operating Activity, Including Discontinued Operation
Net cash used in operating activities
Schedule of Common Stock Shares Reserved for Future Issuance
Schedule Of Common Stock Shares Reserved For Future Issuance [Table TextBlock]
Schedule of common stock shares reserved for future issuance
Issuance Of Common Stock And Pre Funded Warrants In the Pre Closing Financing Net Of Issuance Costs Share
Issuance of common stock and pre funded warrants in the pre closing financing net of issuance costs share
Issuance of common stock and pre-funded warrants in connection with public offering, net of issuance costs, shares
Segment Reporting, CODM, Profit (Loss) Measure, How Used, Description
Segment Reporting, CODM, Profit (Loss) Measure, How Used, Description
Common Stock
Common Stock [Member]
Common Stock [Member]
Collaborative Arrangement, Revenue Not from Contract with Customer, Statement of Income or Comprehensive Income [Extensible Enumeration]
Weighted-Average Exercise Price, Granted
Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Grants in Period, Weighted Average Exercise Price
Lessee, Operating Lease, Liability, to be Paid, Year Three
2029
Less: accumulated depreciation
Less: accumulated depreciation
Accumulated Depreciation, Depletion and Amortization, Property, Plant, and Equipment
Accumulated Depreciation, Depletion and Amortization, Property, Plant, and Equipment, Ending Balance
Accumulated Depreciation, Depletion and Amortization, Property, Plant, and Equipment, Beginning Balance
Accumulated Depreciation, Depletion and Amortization, Property, Plant, and Equipment, Total
Debt Securities, Available-for-Sale [Line Items]
Entity Address, Address Line One
Schedule of Share-Based Payment Award, Stock Options, Valuation Assumptions [Table Text Block]
Schedule of Grant-Date Fair Value of Stock Options Issued, Presented on a Weighted Average Basis
Fair Value Hierarchy and NAV [Axis]
Fair Value Hierarchy and NAV [Axis]
Earnings Per Share [Abstract]
Supplemental Cash Flow Information [Abstract]
Supplemental Disclosure
Sale Of Stock Consideration Received On Transaction, Gross
Sale of stock consideration received on transaction gross.
Gross proceeds from the underwritten offering
Inducement plan.
Inducement Plan [Member]
Inducement Plan [Member]
Number of shares reserved and available for issuance increment percentage
Share Based Compensation Arrangement By Share Based Payment Award Reserved And Available For Issuance Increment Percentage
Share based compensation arrangement by share based payment award reserved and available for issuance increment percentage.
Operating Lease, Right-of-Use Asset
Operating Lease, Right-of-Use Asset
Right-of-use operating lease assets
Preclinical Study Activity Costs [Member]
Preclinical study activity costs.
Preclinical study activity costs [Member]
Class of Warrant or Right [Axis]
Other current assets
Business Combination, Recognized Asset Acquired, Other Asset, Current
Document Type
Collaborative Arrangement and Arrangement Other than Collaborative [Axis]
Type of Arrangement and Non-arrangement Transactions [Axis]
Accrued external research and development
Carrying value as of the balance sheet date of obligations incurred through that date and payable for research and development expenses.
Accrued external research and development expenses current
Collaborative Arrangement and Arrangement Other than Collaborative [Domain]
Arrangements and Non-arrangement Transactions [Domain]
Entity Central Index Key
Chemistry Manufacturing and Control Activity Costs [Member]
Chemistry manufacturing and control activity costs.
Chemistry, manufacturing and control activity costs [Member]
Cash, Cash Equivalent, Restricted Cash, and Restricted Cash Equivalent, Period Increase (Decrease), Including Exchange Rate Effect and Discontinued Operation
Increase/(decrease) in cash, cash equivalents and restricted cash
Subsequent Event Type [Domain]
Interest Income, Operating
Total interest and investment income
Antidilutive Securities Excluded from Computation of Earnings Per Share, Amount
Anti-dilutive securities excluded from computation of earnings per share, amount
Impairment of Long-Lived Assets to be Disposed of
Impairment charge of lab equipment
Common Stock, Par or Stated Value Per Share
Common stock, Par value
Other Comprehensive Income (Loss), Net of Tax, Portion Attributable to Parent
Total other comprehensive (loss)/income
Exercised of pre-funded warrants, Shares
Exercise of Pre Funded warrants
Exercise of pre funded warrants.
Operating Lease, Right-of-Use Asset, Periodic Reduction
Amortization of right-of-use operating lease assets
Weighted Average Remaining Contractual Term
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Remaining Contractual Term
Debt Securities, Available-for-Sale, Amortized Cost
Amortized Cost, Marketable securities
Amortized Cost, Marketable securities
Short-term investments
Debt Securities, Available-for-Sale
Fair Value, Marketable secuirities
Fair Value, Marketable secuirities
First Development Program [Member]
First Development Program [Member]
First development program member.
Gain (Loss) on Termination of Lease
Gain Loss On Termination Of Lease
Loss on lease termination
Loss on lease termination
Certain Incentive Stock Options [Member]
Certain Incentive Stock Options [Member]
Number of Shares, Exercised
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercises in Period
Exercise of stock options, shares
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Nonvested, Number of Shares
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Nonvested, Number of Shares, Beginning Balance
Number of Shares, options unvested at March 31, 2026
Issuance Costs in Connection With Public Offering Included in Accrued Expenses
Issuance costs in connection with public offering included in accrued expenses.
Issuance costs in connection with public offering included in accrued expenses
Accrued expenses
Accrued Liabilities, Current
Accrued Liabilities, Current, Total
Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Line Items]
Share-based Compensation Arrangement by Share-based Payment Award, Compensation Cost [Line Items]
Current Fiscal Year End Date
Document Quarterly Report
Loss on disposal and impairment.
Loss on Disposal and Impairment [Member]
Loss on Disposal and Impairment [Member]
First Selected Antibody [Member]
First Selected Antibody [Member]
First selected antibody member.
Entity Address, State or Province
Preferred Stock, Shares Outstanding
Preferred Stock, Shares Outstanding, Ending Balance
Preferred Stock, Shares Outstanding, Beginning Balance
Preferred stock, Shares outstanding
Comprehensive Income (Loss), Net of Tax, Attributable to Parent
Total comprehensive loss
Debt Securities, Available-for-Sale, Accumulated Gross Unrealized Gain, before Tax, Total
Debt Securities, Available-for-Sale, Accumulated Gross Unrealized Gain, before Tax
Gross Unrealized Gain, Marketable securities
Total common stock reserved for future issuance
Common Stock, Capital Shares Reserved for Future Issuance
Class of Warrant or Right [Domain]
Alloy Therapeutics Llc [Member]
Alloy Therapeutics, LLC [Member]
Alloy therapeutics, llc member.
Prepaid subscriptions, software and other administrative services
Prepaid Subscriptions, Software and Other Administrative Services
Prepaid subscriptions, software and other administrative services.
Prepaid materials, supplies and research and development services
Prepaid Materials, Supplies and Research and Development Services
Prepaid materials, supplies and research and development services.
License [Member]
License [Member]
Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Table Text Block]
Schedule of Stock Based Compensation Expense
Issuance Costs in Connection With Public Offering Included in Accounts Payable
Issuance costs in connection with public offering included in accounts payable.
Issuance costs in connection with public offering included in accounts payable
Stock Issued During Period, Value, Stock Options Exercised
Exercise of stock options
Accrued Expenses
Accounts Payable, Accrued Liabilities, and Other Liabilities Disclosure, Current [Text Block]
Leases.
Leases [Line Items]
Subsequent Event [Member]
Subsequent Event [Member]
Deferred revenue current
Deferred Revenue, Current
Deferred Revenue, Current, Total
Current portion of deferred revenue
Property, Plant and Equipment [Abstract]
Additional number of shares reserved and available for issuance
Additional number of shares reserved and available for issuance
Share-Based Compensation Arrangement by Share-Based Payment Award, Number of Additional Shares Authorized
Debt Securities, Available-for-Sale, Current
Short-term investments
Antidilutive Securities [Axis]
Revenue, Product and Service [Extensible Enumeration]
Summary of Significant Accounting Policies
Basis of Presentation and Significant Accounting Policies [Text Block]
AOCI Attributable to Parent [Member]
Accumulated Other Comprehensive Income (Loss) [Member]
Other Commitments [Table]
Other Commitments [Table]
Receivable associated with exercise of stock options
Receivable Associated With Exercise Of Stock Options
Receivable associated with exercise of stock options.
Preferred Stock, Value, Issued
Preferred stock; $0.001 par value per share; authorized shares - 10,000,000 at March 31, 2026 and December 31, 2025; issued and outstanding - none at March 31, 2026 and December 31, 2025
Second Selected Antibody [Member]
Second Selected Antibody [Member]
Second selected antibody member.
Minimum [Member]
Minimum [Member]
Financial Instrument [Axis]
Assets, Current [Abstract]
Current assets:
Organization Consolidation And Presentation Of Financial Statements Disclosure [Table]
Organization Consolidation And Presentation Of Financial Statements Disclosure [Table]
Organization Consolidation And Presentation Of Financial Statements Disclosure [Table]
Segment Reporting [Abstract]
Fair Value, Assets Measured on Recurring Basis [Table Text Block]
Schedule of Financial Assets Measured at Fair Value on Recurring Basis
Liabilities, Current [Abstract]
Current liabilities:
Product [Member]
Restructuring and Related Activities Disclosure [Text Block]
Restructuring and Other Charges
Convertible preferred stock, Terms of conversion
Preferred Stock, Convertible, Terms
Related Party Transactions [Abstract]
Payments for Repurchase of Warrants
Aggregate purchase price of pre-funded warrant
Common stock, Shares outstanding
Shares, Outstanding
Ending balance, shares
Beginning balance, shares
Accounts Receivable, after Allowance for Credit Loss, Current
Accounts Receivable, after Allowance for Credit Loss, Current, Total
Accounts receivable, net
Accounts receivable
Other Income
Other Income
Restricted Cash and Cash Equivalent
Total cash, cash equivalents and restricted cash
Commitments and Contingencies
Commitments and contingencies (Note 14)
Other assets and restricted cash
Other Assets and Restricted Cash Investment in Former Related Party
Other assets and restricted cash investment in former related party.
Warrant per grant date fair value
Weighted average grant date fair value per share, Ending Balance
Weighted average grant date fair value per share, Beginning Balance
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Weighted Average Grant Date Fair Value
General and Administrative Expense [Member]
General and Administrative Expenses [Member]
Present value of operating lease liabilities
Operating Lease, Liability
Total operating lease liabilities
Total operating lease liabilities
Reverse stock split description
Stockholders' Equity, Reverse Stock Split
Reverse stock split
Cash and cash equivalents amortized cost
Cash and cash equivalents amortized cost
Amortized Cost, Cash And Cash Equivalents
Concentration Risk Benchmark [Axis]
Concentration Risk Benchmark [Axis]
Vesting period
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Outstanding, Weighted Average Remaining Contractual Terms
Net Income (Loss), Including Portion Attributable to Noncontrolling Interest
Net loss
Net Income (Loss), Including Portion Attributable to Noncontrolling Interest, Total
Cash and cash equivalents
Business Combination, Recognized Asset Acquired, Cash and Cash Equivalent
Zenas BioPharma Inc.
Zenas BioPharma Inc [Member]
Weighted-average number of shares of common stock outstanding including shares issuable under equity-classified pre-funded warrants, used in computing net loss per share of common stock, basic
Weighted Average Number of Shares Outstanding, Basic
Weighted Average Number of Shares Outstanding, Basic, Total
Weighted-average number of shares of common stock outstanding, used in computing net loss per share of common stock, basic
Accrued Payroll Taxes, Current
Accrued payroll tax withholding on stock option exercises
Development milestones
Revenue Recognition Milestone Method Pending
Revenue recognition milestone method pending.
Gross unrealized holding gains cash and cash equivalents
Gross unrealized holding gains cash and cash equivalents
Gross Unrealized Gain, Cash And Cash Equivalents
Exchange ratio of reverse merger
Split Adjusted Exchange Ratio of Reverse Merger
Split adjusted exchange ratio of reverse merger.
Schedule of Share-Based Compensation Arrangements by Share-Based Payment Award [Table]
Schedule of Share-based Compensation Arrangements by Share-based Payment Award [Table]
Long-Lived Tangible Asset [Domain]
Prefunded Warrants.
Prefunded Warrants [Member]
Pre-funded Warrants [Member]
Cash Equivalents and Marketable Securities [Abstract]
Cash Equivalents and Marketable Securities [Abstract].
APIC, Share-Based Payment Arrangement, Increase for Cost Recognition
Stock-based compensation expense
APIC, Share-Based Payment Arrangement, Increase for Cost Recognition, Total
Equity, Attributable to Parent
Ending balance
Beginning balance
Total stockholders' equity
Purchases of investment securities
Payments to Acquire Investments, Total
Payments to Acquire Investments
Purchases of investment securities
Preferred Stock, Par or Stated Value Per Share
Preferred stock, par value
Basis of Presentation
Basis of Accounting, Policy [Policy Text Block]
Statement of Stockholders' Equity [Abstract]
The potential milestone payment that may be received as part of an asset purchase agreement.
Potential Milestone Receivable Asset Purchase Agreement
Milestone Payment
Type of Restructuring [Domain]
Use of Estimates, Policy [Policy Text Block]
Use of Estimates
Gross unrealized losses cash and cash equivalents
Gross unrealized losses cash and cash equivalents
Gross Unrealized Loss Cash And Cash Equivalents
Gain (Loss), Foreign Currency Transaction, before Tax
Gain (Loss), Foreign Currency Transaction, before Tax, Total
Loss on currency exchange, net
Fair Value of Financial Instruments
Fair Value Disclosures [Text Block]
Adam Veness [Member]
Adam Veness.
Adam Veness
Marino Garcia [Member]
Marino Garcia.
Marino Garcia
Pre-Funded warrants exercisable
Pre-Funded Warrants Exercisable
Pre-funded warrants exercisable
Schedule of Accrued Expenses
Schedule of Accrued Liabilities [Table Text Block]
Other Assets, Current
Other current assets
Share Based Compensation Arrangement By Share Based Payment Award Options Nonvested Weighted Average Remaining Contractual Term1
Share based compensation arrangement by share based payment award options nonvested weighted average remaining contractual term1.
Weighted Average Remaining Contractual Term, Options unvested as of March 31, 2026
Accrued expenses
Accrued Liabilities and Other Liabilities
Accrued expenses and other current liabilities
Common stock exercise price
Share-Based Compensation Arrangement by Share-Based Payment Award, Per Share Weighted Average Price of Shares Purchased
Segment Reporting, CODM, Individual Title and Position or Group Name [Extensible Enumeration]
Plan Name [Domain]
Plan Name [Domain]
Other assets
Increase (Decrease) in Other Operating Assets
Increase (Decrease) in Other Operating Assets, Total
Amounts owed under license agreement
Amounts Owed under License Agreement
Amounts owed under license agreement.
2018 Amended Plan [Member]
Two Thousand And Eighteen Amended Plan [Member]
Two thousand and eighteen amended plan.
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Entity [Domain]
Entity [Domain]
Stock-based compensation expense [Member]
Share Based Compensation Expense [Member]
Share based compensation expense.
Contract Termination [Member]
Lease Termination [Member]
Organization, Description of Business and Liquidity
Business Description and Basis of Presentation [Text Block]
Stock Options and Stock Appreciation Rights [Member]
Stock Options and Stock Appreciation Rights [Member]
Certificates of Deposit [Member]
Certificate of deposit
Pre-funded warrants outstanding
Class of Warrant or Right, Outstanding
Pre-funded warrants outstanding
Related and Nonrelated Parties [Axis]
Class of Warrant or Right [Table]
Entity Address, City or Town
Number of Reportable Segments
Number of reportable segments
Proceeds from pre-closing financing
Proceeds from Pre Closing Financing
Proceeds from pre closing financing.
Security Exchange Name
Property and equipment, gross
Property, Plant and Equipment, Gross
Property, Plant and Equipment, Gross, Ending Balance
Property, Plant and Equipment, Gross, Beginning Balance
Property, Plant and Equipment, Gross, Total
Antidilutive Securities, Name [Domain]
Gain Loss on Investment in Former Related Party
Gain loss on investment in former related party.
Loss on investment in former related party
Loss on investment in former related party
Stockholders' Equity Note [Abstract]
Milestone [Member]
Milestone [Member]
Milestone.
Cash, cash equivalents and restricted cash, end of period
Cash, cash equivalents and restricted cash, beginning of period
Cash, Cash Equivalent, Restricted Cash, and Restricted Cash Equivalent, Continuing Operation
Cash, Cash Equivalents, Restricted Cash, and Restricted Cash Equivalents, Total
Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Table]
Schedule of Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Table]
Range [Domain]
Statistical Measurement [Domain]
Class of Warrant or Right, Exercise Price of Warrants or Rights
Exercise price (in USD per share)
Public offering price
Assets, Current
Total current assets
Share-Based Payment Arrangement, Expense
Stock based compensation expense
Interest Income, Securities, Operating, by Taxable Status [Abstract]
Dianthus member
Dianthus [Member]
Dianthus
Dianthus [Member]
Document Period End Date
Fair Value Hierarchy and NAV [Domain]
Fair Value Hierarchy and NAV [Domain]
Class of warrant or right maximum beneficial ownership percent
Class Of Warrant Or Right Maximum Beneficial Ownership Percent
Class of warrant or right maximum beneficial ownership percent
License agreement.
License Agreement [Member]
License Agreement [Member]
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Number
Number of shares, options vested and expected to vest
Number of Shares, Options exercisable at March 31, 2026
Prefunded warrants price per share
Prefunded Warrants Price Per Share
Prefunded warrants price per share
Statement of Financial Position [Abstract]
Antidilutive Security, Excluded EPS Calculation [Table]
Other Comprehensive Income (Loss), Net of Tax, Portion Attributable to Parent [Abstract]
Other comprehensive (loss)/income:
Class of Stock [Axis]
Class of Stock [Axis]
Accrued liabilities
Accrued liabilities
Business Combination, Recognized Identifiable Assets Acquired and Liabilities Assumed, Accrued Liabilities
Business combination, recognized identifiable assets acquired and liabilities assumed, accrued liabilities.
Payment of issuance costs in connection with public offering
Payments of Issuance Costs Public Offering
Payments of issuance costs public offering.
Other assets and restricted cash
Other Assets and Restricted Cash
Other assets and restricted cash.
Liabilities
Total liabilities
Financial Instruments [Domain]
Restructuring and Related Cost, Incurred Cost
Expense incurred
Restructuring charge related to severance cost
Increase (Decrease) in Deferred Revenue
Deferred revenue
IONTAS Limited [Member]
IONTAS Limited [Member]
IONTAS limited member.
Lessee, Operating Lease, Liability, to be Paid, Year Two
2028
Restricted cash
Restricted Cash
Restricted Cash, Total
Restricted Stock
Restricted Stock [Member]
Proceeds from Issuance of Common Stock Public Offering
The cash inflow associated with the issuance of common stock public offering.
Proceeds from public offering
Prepaid Expense and Other Assets, Current [Abstract]
March Two Thousand Twenty Six Public Offering [Member]
March two thousand twenty six public offering.
March 2026 Public Offering [Member]
Weighted-average number of shares of common stock outstanding including shares issuable under equity-classified pre-funded warrants, used in computing net loss per share of common stock, diluted
Weighted Average Number of Shares Outstanding, Diluted
Weighted Average Number of Shares Outstanding, Diluted, Total
Weighted-average number of shares of common stock outstanding, used in computing net loss per share of common stock, diluted
Interest and Other Income [Table Text Block]
Schedule of Components of Interest Income
Securities Act File Number
OCI, Debt Securities, Available-for-Sale, Unrealized Holding Gain (Loss), before Adjustment, after Tax
OCI, Debt Securities, Available-for-Sale, Unrealized Holding Gain (Loss), before Adjustment, after Tax, Total
Unrealized gain (loss) on marketable securities
Unrealized (loss)/gain on marketable securities
Development Milestone [Member]
Development Milestone [Member]
Development milestone.
Cover [Abstract]
Commercial Milestone [Member]
Commercial Milestone [Member]
Commercial milestone.
Accounts payable, accrued expenses and operating lease liabilities.
Accounts Payable, Accrued Expenses and Operating Lease Liabilities
Accounts payable, accrued expenses and operating lease liabilities
Prepaid expenses and other current assets
Prepaid Expense and Other Assets, Current
Prepaid expenses and other current assets
US Treasury Securities [Member]
U.S. Treasury Securities
Share-Based Compensation Arrangement by Share-Based Payment Award, Number of Shares Authorized
Share-based compensation arrangement by share-based payment award, number of shares authorized
Number of Operating Segments
Number of operating segments
Sale of Stock [Domain]
Sale of Stock [Domain]
Accrued liabilities and other liabilities.
Accrued Liabilities And Other Liabilities [Line Items]
Accrued Liabilities And Other Liabilities [Line Items]
Segment Reporting Disclosure [Text Block]
Segment Reporting
General and Administrative Expense
General and administrative
General and administrative expense
Total general and administrative expenses
Total general and administrative expenses
Business Combination, Asset Acquisition, Transaction between Entities under Common Control, and Joint Venture Formation [Abstract]
Issuance of common stock upon exercise of stock options
Issuance of Common Stock Upon Exercise of Stock Options
Issuance of common stock upon exercise of stock options
Convertible preferred stock, Liquidation Preference
Temporary Equity, Liquidation Preference
Exercised of pre-funded warrants
Exercise of PreFunded Warrants Value
Exercise of preFunded warrants value.
Subsequent Event [Table]
Shares Available for Issuance under the Employee Stock Purchase Plan
Shares available for issuance under the Employee Stock Purchase Plan
Shares available for issuance under employee stock purchase plan
Exercise Of Warrants And Pre-funded Warrants
Exercise of warrants and pre-funded warrants.
Short-Term Debt, Type [Domain]
Short-term Debt, Type [Domain]
Share-Based Compensation Arrangement by Share-Based Payment Award, Option, Nonvested, Weighted Average Exercise Price
Weighted-Average Exercise Price, Options unvested as of March 31, 2026
Short-Term Debt, Type [Axis]
Short-term Debt, Type [Axis]
Recently Adopted Accounting Pronouncements
New Accounting Pronouncements, Policy [Policy Text Block]
Schedule of Maturities of Operating Lease Liabilities
Lessee, Operating Lease, Liability, to be Paid, Maturity [Table Text Block]
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]
Vesting period
Share-Based Compensation Arrangement by Share-Based Payment Award, Award Vesting Period
Employee Severance [Member]
Employee-Related Costs [Member]
Depreciation expense
Depreciation
Depreciation, Total
Other Receivables, Net, Current
Other Receivables, Net, Current, Total
Receivable from former related party
Long-Term Investments, Total
Long-Term Investments
Long-term investments
Marketable secuirities, Long-term
Common Stock, Shares, Outstanding
Common Stock, Shares, Outstanding, Ending Balance
Common Stock, Shares, Outstanding, Beginning Balance
Common stock, Shares outstanding
Operating Lease, Liability, Current
Operating lease liability, current portion
Current portion of operating lease liabilities
Document Transition Report
Short-Term Investments
Short-Term Investments, Total
Short-term investments
Marketable secuirities, Short-term
Operating Expenses
Total operating expenses
Research and Development Expense
Research and development
Research and development expense
Total research and development expenses
Total research and development expenses
Payment of annual license fees and program fees
Payment of Annual License Fees and Annual Antibody Program Fees
Payment of annual license fees and annual antibody program fees.
Lessee, Operating Leases [Text Block]
Leases
Convertible Preferred Stock [Member]
Convertible Preferred Stock
Convertible Preferred Stock [Member]
No Trading Symbol Flag
Statement of Cash Flows [Abstract]
Stock Issued During Period, Value, New Issues
Issuance of common stock pursuant to at-the-market offering, net of issuance costs
Schedule of Stock Option Activity
Share-Based Payment Arrangement, Option, Activity [Table Text Block]
Common Stock
Equity [Text Block]
Stockholders' Equity
Earnings Per Share [Text Block]
Net Loss Per Share
Schedule of Activity Relating to Restricted Stock Units
Share-Based Payment Arrangement, Restricted Stock Unit, Activity [Table Text Block]
Computer Equipment [Member]
Net loss
Net loss
Net loss
Aggregate Intrinsic Value, Ending Balance
Aggregate Intrinsic Value, Beginning Balance
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Intrinsic Value
Operating Lease, Cost
Operating lease cost
CMC Activities [Member]
CMC activities.
CMC activities [Member]
Expected dividend yield
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Dividend Rate
Weighted-average maturity of the securities held
Weighted average maturities of available for sale debt securities.
Weighted Average Maturities of Available for Sale Debt Securities
Operating Lease, Payments
Operating lease, payments
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Exercisable, Aggregate Intrinsic Value
Aggregate Intrinsic Value, Options exercisable at March 31, 2026
Assets [Abstract]
Assets
Risk-free interest rate
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Risk Free Interest Rate
Increase (Decrease) in Prepaid Expense and Other Assets
Prepaid expenses and other current assets
Restructuring and Related Activities [Abstract]
Document Fiscal Year Focus
Concentration Risk Benchmark [Domain]
Concentration Risk Benchmark [Domain]
Cash Provided by (Used in) Investing Activity, Including Discontinued Operation [Abstract]
Cash flows from investing activities:
Accounts Payable, Current
Accounts payable
Accounts Payable, Current, Total
Research and Development Expense [Member]
Research and Development Expenses [Member]
Restructuring Cost and Reserve [Line Items]
Equity awards available for grant under stock award plans.
Equity Awards Available for Grant Under Stock Award Plans
Equity awards available for grant under stock award plans
2019 Employee Stock Purchase Plan [Member]
Two thousand and nineteen employee stock purchase plan.
Two Thousand And Nineteen Employee Stock Purchase Plan [Member]
Proceeds from issuance of common stock pursuant to at-the-market offering, net of issuance costs
Proceeds From Issuance Of Common Stock Pursuant To At-The-Market Offering, Net Of Issuance Costs
Proceeds from issuance of common stock pursuant to at-the-market offering, net of issuance costs.
Proceeds from Stock Options Exercised
Proceeds from exercise of stock options (net of receivable for stock option proceeds in transit)
Fair Value Disclosures [Abstract]
Increase Decrease in Receivable from Former Related Party
Increase decrease in receivable from former related party.
Receivable from former related party
Commitments and Contingencies Disclosure [Abstract]
Value of stock and debt instruments authorized to issue
Maximum value of stock and debt instruments authorized to issue.
Maximum Value Of Stock and Debt Instruments Authorized to Issue
Lessee, Operating Lease, Liability, to be Paid, Year One
2027
Sale of stock remaining amount authorized
Sale of stock remaining amount authorized.
Sale of stock remaining amount authorized
Net assets acquired
Business Combination, Recognized Asset Acquired to Liability Assumed, Excess (Less)
Share-Based Payment Arrangement [Abstract]
Share-Based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Amount
Total unrecognized stock-based compensation expense related to unvested share-based awards
Share-Based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Amount, Total
Total assets measured at fair value
Assets, Fair Value Disclosure
Sale of Stock [Axis]
Sale of Stock [Axis]
Issuance of Common Stock and Pre-funded Warrants in the Pre-closing Financing Net of Issuance Costs
Issuance of common stock and pre-funded warrants in the pre-closing financing net of issuance costs.
Issuance of common stock and pre-funded warrants in connection with public offering, net of issuance costs
WeightedAverageCommonSharesOutstanding
Weighted-average common shares outstanding.
Weighted-average number of shares of common stock outstanding
Weighted-average shares of common stock outstanding
Total revenues
Revenues
Revenues
Total revenues
Cash Provided by (Used in) Investing Activity, Including Discontinued Operation
Net cash (used in)/provided by investing activities
Private Placement [Member]
2024 Private Placement [Member]
Fair Value on Recurring Basis Level 3
Fair Value, Measurement with Unobservable Inputs Reconciliation, Recurring Basis, Asset Transfers Into Level 3
Title of 12(b) Security
Schedule of Segment Reporting Information, by Segment [Table]
Rule 10b5-1 Arrangement Modified [Flag]
Rule 10b5-1 Arrangement Modified [Flag]
Rule 10b5-1 Arrangement Modified
Gain Loss on Investment in Former Related Parties
Gain Loss on investment in former related parties.
Loss on investment in former related party
Loss on investment in former related party
Weighted-Average Exercise Price, Forfeited
Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Forfeitures in Period, Weighted Average Exercise Price
Money Market Funds
Money Market Funds [Member]
Related and Nonrelated Parties [Domain]
Fair value of investments in related party.
Fair Value of Investments in Related Party
Fair value of the investment
Convertible preferred stock, Share issued
Temporary Equity, Shares Issued
Class of Warrant or Right [Line Items]
Organization consolidation and presentation of financial statements disclosure.
Organization Consolidation And Presentation Of Financial Statements Disclosure [Line Items]
Organization Consolidation And Presentation Of Financial Statements Disclosure [Line Items]
Lessee, Operating Lease, Liability, to be Paid, Remainder of Fiscal Year
2026 (remaining 9 months)
Fair Value on Recurring Basis Level 1
Fair Value, Measurement with Unobservable Inputs Reconciliation, Recurring Basis, Asset Transfers Into Level 1
Fair Value, Measurement with Unobservable Inputs Reconciliation, Recurring Basis, Asset Transfers Into Level 1
Legal Entity [Axis]
Legal Entity [Axis]
Adjustment to Reconcile Net Income to Cash Provided by (Used in) Operating Activity, Increase (Decrease) in Operating Capital [Abstract]
Changes in operating assets and liabilities:
Schedule of Property and Equipment, Net
Property, Plant and Equipment [Table Text Block]
Weighted-Average Exercise Price, Outstanding, Ending balance
Weighted-Average Exercise Price, Outstanding, Beginning balance
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Exercise Price
Preferred Stock and Convertible Preferred Stock
Preferred Stock [Text Block]
Fair Value, Recurring and Nonrecurring [Table]
Fair Value Measurements, Recurring and Nonrecurring [Table]
Additional Paid-in Capital [Member]
Additional Paid-in Capital [Member]
Schedule Of Cash Cash Equivalents And Short Term And Long Term Investments Table Text Block
Schedule of cash cash Equivalents and short term and long term investments table text block.
Schedule of Fair Value of the Company's Cash Equivalents and Marketable Securities
Measurement Frequency [Domain]
Fair Value, Measurement Frequency [Domain]
Statement of Income Location, Balance [Axis]
Income Statement Location [Axis]
Potential Development Regulatory and Sales Based Milestone Payments Due
Potential development regulatory and sales based milestone payments due.
Development and regulatory approval and sales based milestone due
Trading Symbol
Property and Equipment
Property, Plant and Equipment Disclosure [Text Block]
Related Party Transaction [Table]
Schedule of Related Party Transactions, by Related Party [Table]
Subsequent Event Type [Axis]
2019 Stock Plan [Member]
Two Thousand and Nineteen Stock Plan [Member]
Two Thousand and Nineteen Stock Plan.
Accrued compensation
Employee-related Liabilities, Current
Accrued restructuring, Ending Balance
Accrued restructuring, Beginning Balance
Employee-related Liabilities, Current, Total
Cash Provided by (Used in) Financing Activity, Including Discontinued Operation [Abstract]
Cash flows from financing activities:
Expected term
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Term
Fair Value on Recurring Basis
Fair Value, Recurring [Member]
Entity Ex Transition Period
Total undiscounted operating lease payments
Lessee, Operating Lease, Liability, to be Paid
Accrued Liabilities And Other Liabilities [Table]
Accrued Liabilities And Other Liabilities [Table]
Accrued Liabilities And Other Liabilities [Table]
Less: imputed interest
Lessee, Operating Lease, Liability, Undiscounted Excess Amount
Property, Plant and Equipment Assets Held-for-Sale Disclosure [Abstract]
Equity Components [Axis]
Equity Components [Axis]
Fair Value, Measurement with Unobservable Inputs Reconciliation, Recurring Basis, Asset Transfers Into Level 2
Fair Value on Recurring Basis Level 2
Fair Value, Measurement with Unobservable Inputs Reconciliation, Recurring Basis, Asset Transfers Into Level 2
Total other income
Nonoperating Income (Expense)
Other income, net
Equity Component [Domain]
Equity Component [Domain]
Deferred revenue noncurrent
Deferred Revenue, Noncurrent
Deferred Revenue, Noncurrent, Total
Deferred revenue
Schedule of Company Obtained Assets and Liabilities
Business Combination, Recognized Asset Acquired and Liability Assumed [Table Text Block]
Business Combination [Axis]
Prepaid Insurance
Prepaid Insurance
IPO [Member]
Stock Issued During Period, Shares, Employee Stock Purchase Plans
Common stock purchased
Common stock purchased
Issuance of common stock under employee stock purchase plan (in shares)
Term of award
Share-Based Compensation Arrangement by Share-Based Payment Award, Expiration Period
Investment Income, Interest and Dividend
Total interest and investment income
Interest and investment income
Maximum [Member]
Maximum [Member]
Schedule of Preferred Stock Activity
Schedule of Stock by Class [Table Text Block]
Range [Axis]
Statistical Measurement [Axis]
Other Costs [Member]
Other costs.
Other costs [Member]
The amount of retention costs recorded during the period as part of a corporate restructuring.
Restructuring Retention Costs
Retention amount paid
Weighted-Average Exercise Price, Exercised
Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Exercises in Period, Weighted Average Exercise Price
Two thousand and eighteen stock option and incentive plan.
Two Thousand And Eighteen Stock Option And Incentive Plan [Member]
2018 Stock Option and Incentive Plan [Member]
Common Stock, Value, Issued
Common stock issued
Common stock; $0.001 par value per share; authorized shares - 150,000,000 at March 31, 2026 and December 31, 2025; issued and outstanding shares - 54,582,749 and 43,223,090 at March 31, 2026 and December 31, 2025, respectively
Clinical Operation Activities [Member]
Clinical operation activities.
Clinical operation activities [Member]
Royalty [Member]
Royalty [Member]
Simrat Randhawa [Member]
Simrat Randhawa
Simrat Randhawa.
Comprehensive Income (Loss), Net of Tax, Attributable to Parent [Abstract]
Comprehensive loss:
common Stock Price Per Share
common stock price per share
Common stock price per share
Expected volatility
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Volatility Rate
Preferred Stock, Shares Authorized
Preferred stock, Shares authorized
Ryan Savitz [Member]
Ryan Savitz.
Ryan Savitz
Reverse Merger
Mergers, Acquisitions and Dispositions Disclosures [Text Block]
MGTA-145.
MGTA-145 [Member]
MGTA-145 [Member]
Employee severance and retention.
Employee Severance and Retention [Member]
Related Party Transaction [Line Items]
Related Party Transaction [Line Items]
Business Combination [Table]
Entity Registrant Name
Debt Securities, Available-for-Sale, Accumulated Gross Unrealized Loss, before Tax
Gross Unrealized Loss, Marketable securities
Other Nonoperating Income (Expense)
Other Nonoperating Income (Expense), Total
Other expense
Subsequent Events [Abstract]
Measurement Frequency [Axis]
Measurement Frequency [Axis]
Net proceeds from common stock
Proceeds from Issuance of Common Stock
Proceeds from issuance of common stock under employee stock purchase plan
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Entity Common Stock, Shares Outstanding
Concentration of Credit Risk
Concentration Risk, Credit Risk, Policy [Policy Text Block]
Class Of Warrant Or Right, Stock Price Discount Per Common Share
Class of warrant or right, stock price discount per common share.
Stock price discount per share
Accumulated Other Comprehensive Income (Loss), Net of Tax
Accumulated Other Comprehensive Income (Loss), Net of Tax, Total
Accumulated other comprehensive (loss)/income
Revenue from Collaborative Arrangement, Excluding Revenue from Contract with Customer
Revenue related to milestones
Payments
Payments
Payments for Restructuring
Holder Three [Member]
Holder three.
Warrants issued
Number of units outstanding, Granted
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Grants in Period
Total assets
Assets
Property, Plant and Equipment [Table]
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Weighted Average Remaining Contractual Term
Weighted Average Remaining Contractual Term, Options exercisable as of March 31, 2026
Income Statement [Abstract]
Restructuring Cost [Table]
Cash Equivalents and Marketable Securities
Cash, Cash Equivalent, and Marketable Security [Text Block]
Weighted Average [Member]
WeightedAverageMember
Weighted-average Shares of Common Stock Outstanding
Weighted-average shares of common stock outstanding including shares issuable under equity-classified pre-funded warrants.
Weighted-average number of shares of common stock outstanding including shares issuable under equity-classified pre-funded warrants, used in computing net loss per share of common stock, basic and diluted
Sale of Stock, Number of Shares Issued in Transaction
Number of additional shares issued (in shares)
Shares sold and issued
Stock Issued During Period, Shares, New Issues
Issuance of shares
Issuance of common stock pursuant to at-the-market offering, net of issuance costs,Shares
Lease, Cost [Abstract]
Convertible preferred stock, Shares authorized
Temporary Equity, Shares Authorized
Net loss per share attributable to common stockholders, diluted
Earnings Per Share, Diluted
Net loss per share, diluted
Earnings Per Share, Diluted, Total
City Area Code
Igenica Patent Portfolio And E478 Technology [Member]
Igenica Patent Portfolio and E478 Technology [Member]
The potential amount of milestone payments due upon achievement of specified targets.
Potential Milestone Payments Due
Potential milestone payments due
Milestone Payments [Member]
Milestone Payments [Member]
Milestone payments.
Business Combination [Line Items]
Reimbursement of development costs
Reimbursement of Development Costs
Reimbursement of development costs.
Aggregate Intrinsic Value, Forfeited
Share Based Compensation Arrangement By Share Based Payment Award Aggregate Intrinsic Value Forfeited
Share based compensation arrangement by share based payment award aggregate intrinsic value forfeited.
Upfront Payments Due
Upfront payments due.
Upfront payment due
At the market offering program.
At the Market Offering Program [Member]
ATM Offering Program [Member]
Variable Lease, Cost
Variable lease cost
Stock Issued During Period, Value, Employee Stock Purchase Plan
Issuance of common stock under employee stock purchase plan
Non-Rule 10b5-1 Arrangement Modified [Flag]
Non-Rule 10b5-1 Arrangement Modified [Flag]
Non-Rule 10b5-1 Arrangement Modified
Weighted-Average remaining lease term
Operating Lease, Weighted Average Remaining Lease Term
Segment Reporting Information [Line Items]
Lease Expiration Date
Lease expiration date
Operating lease costs
Total operating lease costs
Lease, Cost
Property, Plant and Equipment, Net
Property and equipment, net
Property and equipment, net
Operating Income (Loss)
Loss from operations
The amount of expense reimbursement that may be received as part of an asset purchase agreement.
Expense Reimbursement Asset Purchase Agreement
Reimbursement Payment
Retained Earnings [Member]
Accumulated Deficit [Member]
Share-Based Payment Arrangement, Noncash Expense
Stock-based compensation expense
Share-Based Payment Arrangement, Noncash Expense, Total
Class Of Warrants, Beneficial Ownership, Exercise Threshold
Class of warrants beneficial ownership, exercise threshold.
Beneficial ownership threshold percentage
Weighted-average discount rate - operating lease
Operating Lease, Weighted Average Discount Rate, Percent
Current portion of lease liabilities
Operating Lease, Liability, Noncurrent
Long-term operating lease liabilities
Level 1
Fair Value, Inputs, Level 1 [Member]
Class of Stock [Line Items]
Cash Provided by (Used in) Financing Activity, Including Discontinued Operation
Net cash provided by financing activities
Net cash provided by financing activities
MGTA-45.
MGTA-45 [Member]
MGTA-45 [Member]
Summary of the Components of Lease Costs and Rent
Lease, Cost [Table Text Block]
Summary of Prepaid Expenses and Other Current Assets
Schedule of Other Current Assets [Table Text Block]
Other income/(expense):
Nonoperating Income (Expense) [Abstract]
Stock Issuance Cost
Stock issuance cost.
Stock issuance cost
Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table Text Block]
Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share
Corporate Debt Securities
Corporate Debt Securities [Member]
Debt Securities, Available-for-Sale [Table]
Entity Interactive Data Current
Statement of Income Location, Balance [Domain]
Income Statement Location [Domain]
Cash Provided by (Used in) Operating Activity, Including Discontinued Operation [Abstract]
Cash flows from operating activities:
Furniture and Fixtures [Member]
Shares issued upon conversion of convertible preferred stock
Convertible Preferred Stock, Shares Issued upon Conversion
Accretion (Amortization) of Discounts and Premiums, Investments
Accretion of discount on investment securities
Accretion of discount on marketable securities, net
Unbilled Receivables, Current
Unbilled receivable
Common Stock, Dividends, Per Share, Declared
Common Stock, Dividends, Per Share, Declared
Entity Tax Identification Number
Revenues [Abstract]
Share Price
Price per share
Local Phone Number
Accounting Policies [Abstract]
Capital expenditures
Capital expenditures
Payments for Capital Improvements
Revenue from Contract with Customer, Excluding Assessed Tax
Total revenues
License revenue - related party
Revenues
MGTA-117.
MGTA-117 [Member]
MGTA-117 [Member]
General and Administrative Expense [Abstract]
General and administrative expenses
Lessee, Operating Lease, Liability, to be Paid, Year Four
2030
Class of Stock [Domain]
Class of Stock [Domain]
Commercial Paper
Commercial Paper [Member]
Share-Based Compensation Arrangement by Share-Based Payment Award, Number of Shares Available for Grant
Shares available for issuance
Share-Based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Period for Recognition
Period for recognition of unrecognized expense
Accrued professional fees
Accrued Professional Fees, Current
Cash and Cash equivalents, short term
Cash, Cash Equivalents, and Short-Term Investments
Cash, Cash Equivalents, and Short-Term Investments, Total
Stock, Class of Stock [Table]
Entity Emerging Growth Company