v3.26.1
License and Collaborations (Details) - USD ($)
$ in Millions
3 Months Ended 12 Months Ended
Mar. 31, 2026
Dec. 31, 2025
Mar. 31, 2025
Dec. 31, 2024
Dec. 31, 2023
Dec. 31, 2020
Dec. 31, 2017
License And Collaboration Agreements [Line Items]              
Total revenues $ 7   $ 8        
Receivable from collaboration partners 3 $ 11          
Other current liabilities 136 154          
Other noncurrent liabilities 119 135          
Taiho Collaboration Agreement              
License And Collaboration Agreements [Line Items]              
Milestone payments     19        
Receivable from collaboration partners 3 10          
Other liabilities 23 44          
AstraZeneca Agreement              
License And Collaboration Agreements [Line Items]              
Milestone payments           $ 24  
Development cost recorded within research and development expenses 5   4        
Other current liabilities 17            
Other noncurrent liabilities   12          
Taiho Pharmaceutical Co., Ltd | Taiho Agreement              
License And Collaboration Agreements [Line Items]              
Option period             5 years
Non refundable and non creditable cash payments             $ 35
Payment for option exercise   15          
Royalties payable term             10 years
Total revenues 2            
Reimbursement of research and development expense 5   9        
Taiho Pharmaceutical Co., Ltd | Taiho Agreement | Minimum              
License And Collaboration Agreements [Line Items]              
Payment for option exercise             $ 3
Taiho Pharmaceutical Co., Ltd | Taiho Agreement | Maximum              
License And Collaboration Agreements [Line Items]              
Payment for option exercise             15
Additional clinical and regulatory milestone payments receivable   172         130
Contingent milestone payments receivable   $ 145         $ 145
STAR-221 Development Activities | Taiho Collaboration Agreement              
License And Collaboration Agreements [Line Items]              
Milestone payments         $ 28    
STAR-121 Development Activities | Taiho Collaboration Agreement              
License And Collaboration Agreements [Line Items]              
Milestone payments       $ 26      
Abmuno License Agreement              
License And Collaboration Agreements [Line Items]              
Additional clinical, regulatory and commercialization milestone payments 88            
Development milestone expense 0   0        
WuXi Biologics License Agreement | anti-PD-1              
License And Collaboration Agreements [Line Items]              
Development milestone expense 0   0        
WuXi Biologics License Agreement | anti-CD39              
License And Collaboration Agreements [Line Items]              
Development milestone expense 0   $ 0        
WuXi Biologics License Agreement | Maximum | anti-PD-1              
License And Collaboration Agreements [Line Items]              
Clinical regulatory milestone payments 50            
Clinical, regulatory and commercialization milestone payments 375            
WuXi Biologics License Agreement | Maximum | anti-CD39              
License And Collaboration Agreements [Line Items]              
Additional clinical, regulatory and commercialization milestone payments $ 14