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Disclosure - Note 2 - Summary of Significant Accounting Policies link:calculationLink link:definitionLink link:presentationLink 008 - Disclosure - Note 3 - Fair Value Measurements link:calculationLink link:definitionLink link:presentationLink 009 - Disclosure - Note 4 - Marketable Securities link:calculationLink link:definitionLink link:presentationLink 010 - Disclosure - Note 5 - Property and Equipment link:calculationLink link:definitionLink link:presentationLink 011 - Disclosure - Note 6 - Accrued Expenses link:calculationLink link:definitionLink link:presentationLink 012 - Disclosure - Note 7 - Commitments and Contingencies link:calculationLink link:definitionLink link:presentationLink 013 - Disclosure - Note 8 - Stock-based Compensation link:calculationLink link:definitionLink link:presentationLink 014 - Disclosure - Note 9 - Stockholders' Equity link:calculationLink link:definitionLink link:presentationLink 015 - Disclosure - Note 10 - Basic and Diluted Net Loss Per Share link:calculationLink link:definitionLink link:presentationLink 016 - Disclosure - Note 11 - License, Research and Collaboration Agreements link:calculationLink link:definitionLink link:presentationLink 017 - Disclosure - Note 12 - Segment Information link:calculationLink link:definitionLink link:presentationLink 995445 - Disclosure - Note 3 - Fair Value Measurements (Tables) link:calculationLink link:definitionLink link:presentationLink 995446 - Disclosure - Note 4 - Marketable Securities (Tables) link:calculationLink link:definitionLink link:presentationLink 995447 - Disclosure - Note 5 - Property and Equipment (Tables) link:calculationLink link:definitionLink link:presentationLink 995448 - Disclosure - Note 6 - Accrued Expenses (Tables) link:calculationLink link:definitionLink link:presentationLink 995449 - Disclosure - Note 7 - Commitments and Contingencies (Tables) link:calculationLink link:definitionLink link:presentationLink 995450 - Disclosure - Note 8 - Stock-based Compensation (Tables) link:calculationLink link:definitionLink link:presentationLink 995451 - 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Disclosure - Note 8 - Stock-based Compensation - Summary of Stock Option Activity (Details) link:calculationLink link:definitionLink link:presentationLink 995466 - Disclosure - Note 8 - Stock-based Compensation - Weighted Average Assumptions (Details) link:calculationLink link:definitionLink link:presentationLink 995467 - Disclosure - Note 8 - Stock-based Compensation - Summary of RSU Activity (Details) link:calculationLink link:definitionLink link:presentationLink 995468 - Disclosure - Note 9 - Stockholders' Equity (Details Textual) link:calculationLink link:definitionLink link:presentationLink 995469 - Disclosure - Note 10 - Basic and Diluted Net Loss Per Share (Details Textual) link:calculationLink link:definitionLink link:presentationLink 995470 - Disclosure - Note 10 - Basic and Diluted Net Loss Per Share - Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share (Details) link:calculationLink link:definitionLink link:presentationLink 995471 - Disclosure - 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