v3.26.1
Subsequent Events (Details) - Takeda Pharmaceuticals - USD ($)
$ in Millions
1 Months Ended
Apr. 28, 2026
Apr. 28, 2026
Apr. 30, 2024
Jan. 31, 2024
Mar. 31, 2026
License And Service          
Subsequent Events          
Profit (loss) share on U.S. profits and losses     50.00%    
License and collaboration agreement | Minimum          
Subsequent Events          
Percentage of royalties     10.00% 14.00%  
License and collaboration agreement | Maximum          
Subsequent Events          
Collaborative arrangement, milestone payment, eligible to receive     $ 305.0    
Additional payment eligible to receive from a collaborative arrangement       $ 200.0  
Percentage of royalties     17.00% 29.00%  
License and collaboration agreement | Food And Drug Administration approval Of new drug application for rusfertide in PV          
Subsequent Events          
Upcoming potential development and regulatory milestone payments receivable       $ 50.0  
License and collaboration agreement | Exercise of full opt out right during the initial opt out period | Maximum          
Subsequent Events          
Collaborative arrangement, milestone payment, eligible to receive       200.0  
License and collaboration agreement | Exercise of full opt-out right          
Subsequent Events          
Upcoming potential development and regulatory milestone payments receivable         $ 775.0
License and collaboration agreement | Exercise of full opt-out right | Maximum          
Subsequent Events          
Collaborative arrangement, milestone payment, eligible to receive       975.0  
License and collaboration agreement | Exercise of full opt-out right | Food And Drug Administration approval Of new drug application for rusfertide in PV          
Subsequent Events          
Upcoming potential development and regulatory milestone payments receivable       $ 75.0  
Subsequent Events | License And Service | Exercise of full opt-out right          
Subsequent Events          
Profit (loss) share on U.S. profits and losses   50.00%      
Subsequent Events | License and collaboration agreement | Maximum          
Subsequent Events          
Additional payment eligible to receive from a collaborative arrangement $ 200.0 $ 200.0      
Subsequent Events | License and collaboration agreement | Exercise of full opt out right during the initial opt out period | Maximum          
Subsequent Events          
Collaborative arrangement, milestone payment, eligible to receive 200.0 200.0      
Subsequent Events | License and collaboration agreement | Exercise of full opt-out right | Food And Drug Administration approval Of new drug application for rusfertide in PV          
Subsequent Events          
Upcoming potential development and regulatory milestone payments receivable $ 75.0 75.0      
Subsequent Events | License and collaboration agreement | Annual net Sales Up to 1.5 billion          
Subsequent Events          
Milestone revenue   $ 775.0      
Subsequent Events | License and collaboration agreement | Annual net Sales Up to 1.5 billion | Minimum          
Subsequent Events          
Percentage of royalties 14.00%        
Subsequent Events | License and collaboration agreement | Annual net Sales Up to 1.5 billion | Maximum          
Subsequent Events          
Percentage of royalties 29.00%        
Annual net sales $ 1,500.0        
Subsequent Events | License and collaboration agreement | Annual net Sales Up to 1.5 billion | Weighted average          
Subsequent Events          
Percentage of royalties 21.00%        
Subsequent Events | License and collaboration agreement | Annual net sales above 1.5 billion          
Subsequent Events          
Percentage of royalties 29.00%        
Subsequent Events | License and collaboration agreement | Annual net sales above 1.5 billion | Minimum          
Subsequent Events          
Annual net sales $ 1,500.0