0000001 - Document - Cover Page link:presentationLink link:calculationLink link:definitionLink 9952151 - Statement - Condensed Consolidated Balance Sheets link:presentationLink link:calculationLink link:definitionLink 9952152 - Statement - Condensed Consolidated Balance Sheets (Parenthetical) link:presentationLink link:calculationLink link:definitionLink 9952153 - Statement - Condensed Consolidated Statements of Loss link:presentationLink link:calculationLink link:definitionLink 9952154 - Statement - Condensed Consolidated Statements of Comprehensive Loss link:presentationLink link:calculationLink link:definitionLink 9952155 - Statement - Condensed Consolidated Statements of Changes in Stockholders’ Equity link:presentationLink link:calculationLink link:definitionLink 9952156 - Statement - Condensed Consolidated Statements of Cash Flows link:presentationLink link:calculationLink link:definitionLink 9952157 - Disclosure - Business Organization link:presentationLink link:calculationLink link:definitionLink 9952158 - Disclosure - Summary of Significant Accounting Policies link:presentationLink link:calculationLink link:definitionLink 9952159 - Disclosure - Sage Acquisition link:presentationLink link:calculationLink link:definitionLink 9952160 - Disclosure - Disaggregated Revenues link:presentationLink link:calculationLink link:definitionLink 9952161 - Disclosure - Investments link:presentationLink link:calculationLink link:definitionLink 9952162 - Disclosure - Fair Value of Financial Instruments link:presentationLink link:calculationLink link:definitionLink 9952163 - Disclosure - Contingent Consideration link:presentationLink link:calculationLink link:definitionLink 9952164 - Disclosure - Goodwill and Intangible Assets, Net link:presentationLink link:calculationLink link:definitionLink 9952165 - Disclosure - Debt link:presentationLink link:calculationLink link:definitionLink 9952166 - Disclosure - Share-Based Payments link:presentationLink link:calculationLink link:definitionLink 9952167 - Disclosure - Loss per Share link:presentationLink link:calculationLink link:definitionLink 9952168 - Disclosure - Income Tax Expense (Benefit) link:presentationLink link:calculationLink link:definitionLink 9952169 - Disclosure - Leases link:presentationLink link:calculationLink link:definitionLink 9952170 - Disclosure - Segment Reporting link:presentationLink link:calculationLink link:definitionLink 9952171 - Disclosure - Collaboration Agreements link:presentationLink link:calculationLink link:definitionLink 9952172 - Disclosure - Composition of Other Balance Sheet Items link:presentationLink link:calculationLink link:definitionLink 9952173 - Disclosure - Commitments and Contingencies link:presentationLink link:calculationLink link:definitionLink 9955511 - Disclosure - Summary of Significant Accounting Policies (Policies) link:presentationLink link:calculationLink link:definitionLink 9955512 - Disclosure - Sage Acquisition (Tables) link:presentationLink link:calculationLink link:definitionLink 9955513 - Disclosure - Disaggregated Revenues (Tables) link:presentationLink link:calculationLink link:definitionLink 9955514 - Disclosure - Investments (Tables) link:presentationLink link:calculationLink link:definitionLink 9955515 - Disclosure - Fair Value of Financial Instruments (Tables) link:presentationLink link:calculationLink link:definitionLink 9955516 - Disclosure - Contingent Consideration (Tables) link:presentationLink link:calculationLink link:definitionLink 9955517 - Disclosure - Goodwill and Intangible Assets, Net (Tables) link:presentationLink link:calculationLink link:definitionLink 9955518 - Disclosure - Share-Based Payments (Tables) link:presentationLink link:calculationLink link:definitionLink 9955519 - Disclosure - Loss per Share (Tables) link:presentationLink link:calculationLink link:definitionLink 9955520 - Disclosure - Income Tax Expense (Benefit) (Tables) link:presentationLink link:calculationLink link:definitionLink 9955521 - Disclosure - Leases (Tables) link:presentationLink link:calculationLink link:definitionLink 9955522 - Disclosure - Segment Reporting (Tables) link:presentationLink link:calculationLink link:definitionLink 9955523 - Disclosure - Collaboration Agreements (Tables) link:presentationLink link:calculationLink link:definitionLink 9955524 - Disclosure - Composition of Other Balance Sheet Items (Tables) link:presentationLink link:calculationLink link:definitionLink 9955525 - Disclosure - Business Organization (Details) link:presentationLink link:calculationLink link:definitionLink 9955526 - Disclosure - Summary of Significant Accounting Policies - Basis of Presentation (Details) link:presentationLink link:calculationLink link:definitionLink 9955527 - Disclosure - Summary of Significant Accounting Policies - Revenue Recognition (Details) link:presentationLink link:calculationLink link:definitionLink 9955528 - Disclosure - Summary of Significant Accounting Policies - Advertising Expense (Details) link:presentationLink link:calculationLink link:definitionLink 9955529 - Disclosure - Summary of Significant Accounting Policies - Insurance Recoveries (Details) link:presentationLink link:calculationLink link:definitionLink 9955530 - Disclosure - Sage Acquisition - Narrative (Details) link:presentationLink link:calculationLink link:definitionLink 9955531 - Disclosure - Sage Acquisition - Schedule of Purchase Price Allocation (Details) link:presentationLink link:calculationLink link:definitionLink 9955532 - Disclosure - Sage Acquisition - Schedule of Acquired Intangible Assets (Details) link:presentationLink link:calculationLink link:definitionLink 9955533 - Disclosure - Disaggregated Revenues - Schedule of Disaggregation of Revenue by Nature (Details) link:presentationLink link:calculationLink link:definitionLink 9955534 - Disclosure - Disaggregated Revenues - Narrative (Details) link:presentationLink link:calculationLink link:definitionLink 9955535 - Disclosure - Investments - Schedule of Unrestricted Marketable Securities (Details) link:presentationLink link:calculationLink link:definitionLink 9955536 - Disclosure - Investments - Narrative (Details) link:presentationLink link:calculationLink link:definitionLink 9955537 - Disclosure - Fair Value of Financial Instruments (Details) link:presentationLink link:calculationLink link:definitionLink 9955538 - Disclosure - Contingent Consideration - Schedule of Current and Long-Term Contingent Consideration (Details) link:presentationLink link:calculationLink link:definitionLink 9955539 - Disclosure - Contingent Consideration - Narrative (Details) link:presentationLink link:calculationLink link:definitionLink 9955540 - Disclosure - Contingent Consideration - Schedule of Reconciliation of the Beginning and Ending Balances Related to the Contingent Consideration (Details) link:presentationLink link:calculationLink link:definitionLink 9955541 - Disclosure - Goodwill and Intangible Assets, Net - Schedule of Goodwill (Details) link:presentationLink link:calculationLink link:definitionLink 9955542 - Disclosure - Goodwill and Intangible Assets, Net - Schedule of Intangible Assets, Net (Details) link:presentationLink link:calculationLink link:definitionLink 9955543 - Disclosure - Goodwill and Intangible Assets, Net - Narrative (Details) link:presentationLink link:calculationLink link:definitionLink 9955544 - Disclosure - Debt (Details) link:presentationLink link:calculationLink link:definitionLink 9955545 - Disclosure - Share-Based Payments - Schedule of Share-based Compensation Expense (Details) link:presentationLink link:calculationLink link:definitionLink 9955546 - Disclosure - Share-Based Payments - Schedule of Stock Option (Details) link:presentationLink link:calculationLink link:definitionLink 9955547 - Disclosure - Share-Based Payments - Schedule of Restricted Stock Units (Details) link:presentationLink link:calculationLink link:definitionLink 9955548 - Disclosure - Share-Based Payments -Schedule of Performance Stock Units (Details) link:presentationLink link:calculationLink link:definitionLink 9955549 - Disclosure - Loss per Share - Schedule of Computation of Basic and Diluted Earnings per Share (Details) link:presentationLink link:calculationLink link:definitionLink 9955550 - Disclosure - Loss per Share - Schedule of Common Stock Equivalents Excluded in the Calculation of Diluted Earnings per Share (Details) link:presentationLink link:calculationLink link:definitionLink 9955551 - Disclosure - Income Tax Expense (Benefit) (Details) link:presentationLink link:calculationLink link:definitionLink 9955552 - Disclosure - Leases - Schedule of Leases Balance Sheet Information (Details) link:presentationLink link:calculationLink link:definitionLink 9955553 - Disclosure - Leases - Supplemental Cash Flows (Details) link:presentationLink link:calculationLink link:definitionLink 9955554 - Disclosure - Leases - Narrative (Details) link:presentationLink link:calculationLink link:definitionLink 9955555 - Disclosure - Segment Reporting - Narrative (Details) link:presentationLink link:calculationLink link:definitionLink 9955556 - Disclosure - Segment Reporting - Schedule of Segment Reporting Information (Details) link:presentationLink link:calculationLink link:definitionLink 9955557 - Disclosure - Collaboration Agreements - Narrative (Details) link:presentationLink link:calculationLink link:definitionLink 9955558 - Disclosure - Collaboration Agreements - Schedule of Revenue, Cost of Revenues, and Expense (Details) link:presentationLink link:calculationLink link:definitionLink 9955559 - Disclosure - Composition of Other Balance Sheet Items - Schedule of Inventory (Details) link:presentationLink link:calculationLink link:definitionLink 9955560 - Disclosure - Composition of Other Balance Sheet Items - Schedule of Inventory as Reported on Balance Sheet (Details) link:presentationLink link:calculationLink link:definitionLink 9955561 - Disclosure - Composition of Other Balance Sheet Items - Schedule of Property and Equipment (Details) link:presentationLink link:calculationLink link:definitionLink 9955562 - Disclosure - Composition of Other Balance Sheet Items - Schedule of Accrued Payable and Accrued Liabilities (Details) link:presentationLink link:calculationLink link:definitionLink 9955563 - Disclosure - Composition of Other Balance Sheet Items - Schedule of Accrued Product Returns and Rebates (Details) link:presentationLink link:calculationLink link:definitionLink 9955564 - Disclosure - Commitments and Contingencies (Details) link:presentationLink link:calculationLink link:definitionLink