Nature of the Business and Basis of Presentation - Additional Information (Detail) - USD ($) $ in Thousands |
3 Months Ended | |||
|---|---|---|---|---|
Feb. 12, 2026 |
Mar. 31, 2026 |
Mar. 31, 2025 |
Dec. 31, 2025 |
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| Nature Of Business And Basis Of Presentation [Line Items] | ||||
| Entity incorporated month and year | 2010-10 | |||
| Restructuring and related cost, number of positions eliminated, period percent | 30.00% | |||
| Restructuring costs | $ 914 | |||
| Severance costs | $ 718 | |||
| Entity incorporation, state or country code | DE | |||
| Net Income (Loss) | $ (19,913) | $ 32,682 | ||
| Accumulated deficit | (992,316) | $ (972,403) | ||
| Cash and cash equivalents | $ 29,834 | 45,766 | ||
| CARB-X [Member] | Maximum [Member] | ||||
| Nature Of Business And Basis Of Presentation [Line Items] | ||||
| Grant Received for Clinical Development | $ 3,583 | |||
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- Definition Two-character EDGAR code representing the state or country of incorporation. No definition available.
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- Definition Entity incorporation month and year of incorporation. No definition available.
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- Definition Grant received for clinical development. No definition available.
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- Definition Nature of business and basis of presentation. No definition available.
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- Definition Amount of cash and cash equivalent. Cash includes, but is not limited to, currency on hand, demand deposit with financial institution, and account with general characteristic of demand deposit. Cash equivalent includes, but is not limited to, short-term, highly liquid investment that is both readily convertible to known amount of cash and so near maturity that it presents insignificant risk of change in value because of change in interest rate. Reference 1: http://www.xbrl.org/2003/role/disclosureRef
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- Definition The portion of profit or loss for the period, net of income taxes, which is attributable to the parent. Reference 1: http://www.xbrl.org/2003/role/exampleRef
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- Definition The number of positions eliminated during the period as a percentage of total positions eliminated during the period in connection with the restructuring plan(s). No definition available.
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- Definition Amount of expenses associated with exit or disposal activities pursuant to an authorized plan. Excludes expenses related to a discontinued operation or an asset retirement obligation. Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
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- Definition Amount of accumulated undistributed earnings (deficit). Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
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- Definition Amount of expenses for special or contractual termination benefits provided to current employees involuntarily terminated under a benefit arrangement associated exit or disposal activities pursuant to an authorized plan. Excludes expenses related to one-time termination benefits, a discontinued operation or an asset retirement obligation. Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
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