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  <xs:element id="efsc_OtherBorrowingsFairValueDisclosure" abstract="false" name="OtherBorrowingsFairValueDisclosure" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="efsc_AOCIAccumulatedGainLossHeldToMaturitySecuritiesParentMember" abstract="true" name="AOCIAccumulatedGainLossHeldToMaturitySecuritiesParentMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="efsc_OtherComprehensiveIncomeLossReclassificationOfGainLossOnHeldToMaturitySecuritiesBeforeOfTax" abstract="false" name="OtherComprehensiveIncomeLossReclassificationOfGainLossOnHeldToMaturitySecuritiesBeforeOfTax" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="efsc_OtherComprehensiveIncomeLossReclassificationofgainlossonheldtomaturitysecuritiestax" abstract="false" name="OtherComprehensiveIncomeLossReclassificationofgainlossonheldtomaturitysecuritiestax" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="efsc_BankOwnedLifeInsuranceMember" abstract="true" name="BankOwnedLifeInsuranceMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="efsc_CommunityDevelopmentFeesMember" abstract="true" name="CommunityDevelopmentFeesMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="efsc_GainOnSaleOfSBALoansMember" abstract="true" name="GainOnSaleOfSBALoansMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="efsc_OtherMiscellaneousIncomeMember" abstract="true" name="OtherMiscellaneousIncomeMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="efsc_TotalOtherNoninterestExpensesMember" abstract="true" name="TotalOtherNoninterestExpensesMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="efsc_AmortizationExpenseMember" abstract="true" name="AmortizationExpenseMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="efsc_BankingExpensesMember" abstract="true" name="BankingExpensesMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="efsc_FDICAndOtherInsuranceMember" abstract="true" name="FDICAndOtherInsuranceMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="efsc_LoanLegalExpenseMember" abstract="true" name="LoanLegalExpenseMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="efsc_OutsideServicesMember" abstract="true" name="OutsideServicesMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="efsc_OtherExpensesMember" abstract="true" name="OtherExpensesMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
</xs:schema>
