0001716947 2026-04-30 2026-04-30 0001716947 1 2026-04-30 2026-04-30 iso4217:USD pure shares S-8 S-8 EX-FILING FEES 0001716947 Ensysce Biosciences, Inc. N/A false S-8 Ensysce Biosciences, Inc. Equity Common Stock, par value $0.0001 per share true 828749 0.381 315753.37 0.0001381 43.61 315753.37 43.61 0.00 43.61 Pursuant to Rules 457(c) and 457(h) under the Securities Act, and solely for the purpose of calculating the registration fee, the proposed maximum offering price per share is the average of the high and low prices reported for the registrant's Common Stock quoted on The Nasdaq Capital Market LLC on April 27, 2026. Represents 828,749 additional shares reserved for issuance under the Ensysce Biosciences, Inc. Amended and Restated 2021 Omnibus Incentive Plan, as amended (the "Plan"). Pursuant to Rule 416(a) under the Securities Act, this registration statement also covers an indeterminate number of additional shares as may be necessary to account for adjustment provisions under the Plan as a result of stock splits, stock dividends or similar transactions.