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    <dei:AmendmentDescription contextRef="From2025-01-01to2025-12-31" id="Fact000048">Interpace
Biosciences, Inc. (&#x201c;Interpace,&#x201d; the &#x201c;Company,&#x201d; &#x201c;we&#x201d;, &#x201c;us&#x201d;
or &#x201c;our&#x201d;) is filing this Amendment No. 1 to Form 10-K (this &#x201c;Amendment&#x201d;) to amend its Annual Report
on Form 10-K for the fiscal year ended December 31, 2025, which was originally filed with the Securities and Exchange Commission (the
&#x201c;SEC&#x201d;) on March 30, 2026 (the &#x201c;Original Filing&#x201d;).We
are filing this Amendment solely for the purpose of including in Part III the information that was to be incorporated by reference from
the Company&#x2019;s definitive proxy statement for its 2025 Annual Meeting of Stockholders because the Company&#x2019;s definitive proxy
statement will not be filed with the SEC within 120 days after the end of the Company&#x2019;s fiscal year ended December 31, 2025. This
Amendment amends and restates in its entirety Items 10, 11, 12, 13 and 14 of Part III and amends and restates in its entirety Part IV
of the Original Filing to include the prior exhibits and additional certifications required of the principal executive officer and principal
financial officer under Section 302 of the Sarbanes-Oxley Act of 2002. Because no financial statements are contained within this Amendment,
we are not including new certifications pursuant to Section 906 of the Sarbanes-Oxley Act of 2002.

&#160;

Except
as described above, no other changes have been made to the Original Filing and the Original Filing continues to speak as of the date
of the Original Filing. Except as expressly set forth herein, this Amendment does not reflect events occurring after the date of the
Original Filing or modify or update any of the other disclosures contained therein in any way other than as required to reflect the amendments
discussed above. Accordingly, this Amendment should be read in conjunction with the Original Filing and the Company&#x2019;s other filings
with the SEC.

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