75000 - Document - Cover Page
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75010 - Statement - Balance Sheets
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75020 - Statement - Balance Sheets (Parenthetical)
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75030 - Statement - Statements of Operations
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75040 - Statement - Statements of Comprehensive Loss
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995457 - Disclosure - Cybersecurity Risk Management, Strategy, and Governance
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995467 - Disclosure - Description of Business and Organization
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995477 - Disclosure - Summary of Significant Accounting Policies
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995487 - Disclosure - Inventory
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995497 - Disclosure - Recent Accounting Guidance
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995507 - Disclosure - Recurring Fair Value Measurements
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995517 - Disclosure - Balance Sheet Items
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995527 - Disclosure - Intangible Assets
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995537 - Disclosure - Prepaid Expenses and Other Current Assets
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995547 - Disclosure - Property and Equipment, Net
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995557 - Disclosure - Accrued Expenses and Other Current Liabilities
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995567 - Disclosure - Significant Agreements
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995577 - Disclosure - Commitments and Contingencies
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995587 - Disclosure - Redeemable Convertible Preferred Shares
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995597 - Disclosure - Common Stock
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995607 - Disclosure - Share-Based Compensation
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995617 - Disclosure - Net Loss Per Share
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995627 - Disclosure - Redeemable Noncontrolling Interest
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995637 - Disclosure - Income Taxes
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995647 - Disclosure - Defined Contribution Plan
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995657 - Disclosure - Segment Reporting
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995667 - Disclosure - Subsequent Events
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995677 - Disclosure - Summary of Significant Accounting Policies (Policies)
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995687 - Disclosure - Inventory (Tables)
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995697 - Disclosure - Recurring Fair Value Measurements (Tables)
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995707 - Disclosure - Balance Sheet Items (Tables)
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995717 - Disclosure - Intangible Assets (Tables)
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995727 - Disclosure - Prepaid Expenses and Other Current Assets (Tables)
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995737 - Disclosure - Property and Equipment, Net (Tables)
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995747 - Disclosure - Accrued Expenses and Other Current Liabilities (Tables)
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995757 - Disclosure - Commitments and Contingencies (Tables)
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995767 - Disclosure - Redeemable Convertible Preferred Shares (Tables)
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995777 - Disclosure - Common Stock (Tables)
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995787 - Disclosure - Share-based Compensation (Tables)
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995797 - Disclosure - Net Loss Per Share (Tables)
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995807 - Disclosure - Income Taxes (Tables)
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995817 - Disclosure - Segment Reporting (Tables)
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995827 - Disclosure - Summary of Significant Accounting Policies - Additional Information (Detail)
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995837 - Disclosure - Recurring Fair Value Measurements - Schedule of Fair Value, Assets and Liabilities Measured on Recurring Basis (Detail)
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995847 - Disclosure - Recurring Fair Value Measurements - Schedule of cash equivalent, marketable securities and unrealized gains and losses (Details)
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995857 - Disclosure - Recurring Fair Value Measurements - Schedule of maturities of our available-for-sale marketable securities (Details)
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995867 - Disclosure - Recurring Fair Value Measurements - Schedule of available -for -sale marketable securities with gross unrealized losses (Details)
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995877 - Disclosure - Recurring Fair Value Measurements - Additional Information (Detail)
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995887 - Disclosure - Inventory - Summary of Inventory (Details)
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995897 - Disclosure - Inventory (Additional Information) (Details)
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995907 - Disclosure - Balance Sheet Items - Schedule of Prepaid Expenses and Other Current Assets (Detail)
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995917 - Disclosure - Balance Sheet Items - Summary of Accrued Expenses and Other Current Liabilities (Detail)
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995927 - Disclosure - Balance Sheet Items - Summary of Accrued Expenses and Other Current Liabilities (Detail) 2
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995937 - Disclosure - Balance Sheet Items - Additional Information (Detail)
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995947 - Disclosure - Intangible Assets - Schedule Of Intangible Assets (Details)
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995957 - Disclosure - Intangible Assets (Additional Information) (Details)
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995967 - Disclosure - Intangible Assets - Schedule Of Amortization Expense For Amortizable Finite-Lived Intangible Assets (Details)
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995977 - Disclosure - Significant Agreements - Additional Information (Detail)
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995987 - Disclosure - Commitments and Contingencies - Additional Information (Detail)
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995997 - Disclosure - Commitments and Contingencies - Summary of Future Lease Obligations (Detail)
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996007 - Disclosure - Commitments and Contingencies - Summary of Future Lease Obligations (Detail) 2
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996017 - Disclosure - Redeemable Convertible Preferred Shares - Additional Information (Detail)
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996027 - Disclosure - Redeemable Convertible Preferred Shares - Summary of Series A Redeemable Convertible Preferred Shares (Detail)
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996037 - Disclosure - Common Stock - Additional Information (Detail)
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996047 - Disclosure - Common Stock - Schedule of Common Stock Shares Reserved for Future Issuance (Detail)
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996057 - Disclosure - Share-based Compensation - Summary of Share/Stock-based Compensation Expense Recorded in The Accompanying Condensed Consolidated Statements of Operations and Comprehensive Loss (Detail)
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996067 - Disclosure - Share-based Compensation - Additional Information (Detail)
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996077 - Disclosure - Share-based Compensation - Summary of Stock Option Activity (Detail)
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996087 - Disclosure - Share-based Compensation - Summary of The Black-Scholes Option Pricing Model to Estimate The Fair Value of Stock Option Granted (Detail)
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996097 - Disclosure - Share-based Compensation - Summary of Restricted Stock Units Activity (Detail)
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996107 - Disclosure - Share-based Compensation - Summary of The Unvested Common Stock (Detail)
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996117 - Disclosure - Share-based Compensation - Summary of Fair Value of The Incentive Shares Estimated Using An Option Pricing Model (Detail)
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996127 - Disclosure - Net Loss Per Share - Summary of Basic and Diluted Net Loss Per Share Attributable to Common Shareholders/Stockholders (Detail)
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996137 - Disclosure - Net Loss Per Share - Summary of Outstanding Potentially Dilutive Securities Have Been Excluded From Calculation of Diluted Net Loss Per Share (Detail)
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996147 - Disclosure - Redeemable Noncontrolling Interest - Additional Information (Detail)
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996157 - Disclosure - Income Taxes - Summary of Significant Components of the Income Tax Provision From Continuing Operations (Details)
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996167 - Disclosure - Income Taxes - Schedule of Effective Income Tax Rate Reconciliation (Detail)
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996177 - Disclosure - Income Tax - Income taxes paid (net of refunds) (Details)
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996187 - Disclosure - Income Taxes - Schedule of Deferred Tax Assets and Liabilities (Detail)
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996197 - Disclosure - Income Taxes - Schedule of Changes in the Valuation Allowance for Deferred Tax Assets (Details)
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996207 - Disclosure - Income Taxes - Additional Information (Detail)
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996217 - Disclosure - Income Taxes - Summary of Unrecognized Tax Benefits (Detail)
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996227 - Disclosure - Defined Contribution Plan (Additional Information) (Details)
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996237 - Disclosure - Segment Reporting (Additional Information) (Details)
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996247 - Disclosure - Segment Reporting - Schedule of Segment Information (Details)
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996257 - Disclosure - Subsequent Event (Additional Information) (Details)
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Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Vested in Period, Weighted Average Grant Date Fair Value
Vested
Vested
Other Research and Development Expense
Other research and development costs
2021 employee stock purchase plan.
Two Thousand And Twenty One Employee Stock Purchase Plan [Member]
Two Thousand And Twenty One Employee Stock Purchase Plan
2021 Employee Stock Purchase Plan [Member]
Concentration Risk Type [Axis]
Entity Incorporation, State or Country Code
Entity Incorporation, State or Country Code
Entity Incorporation, State or Country Code
Cost of license revenue
Cost of License Revenue
Cost of License Revenue
Premium Received On License Agreement
Premium Received On License Agreement
Premium Received On License Agreement
Effective Income Tax Rate Reconciliation, Tax Credit, Amount [Abstract]
Tax credits
Purchase Commitment, Remaining Minimum Amount Committed
Purchases Under the Purchase Obligation
Purchases Under the Purchase Obligation
Debt Securities, Available-for-Sale, Fair Value, Maturity, Allocated and Single Maturity Date, Year One
Fair Value, Mature in one year or less
Redeemable Noncontrolling Interest Policy Text Block
Redeemable Noncontrolling Interest
Redeemable Noncontrolling Interest Policy Text Block
Plan Name [Axis]
Plan Name
Entity Current Reporting Status
Entity Current Reporting Status
Entity Current Reporting Status
Operating Expenses [Abstract]
Operating expenses:
Fair Value, Inputs, Level 2 [Member]
Fair Value, Inputs, Level 2
Current
Current [Member]
Current [Member]
Commitments and Contingencies Disclosure [Text Block]
Commitments and Contingencies
Net Product Revenue and Accounts Receivable [Member]
Net Product Revenue and Accounts Receivable [Member]
Net Product Revenue And Accounts Receivable
Common stock shares authorized
Common Stock, Shares Authorized
Common Stock, Shares Authorized
Finite-Lived Intangible Asset, Expected Amortization, Year Four
2029
Kentucky
KENTUCKY
Option Indexed to Issuer's Equity, Type [Axis]
Investment, Policy [Policy Text Block]
Investments
Product and Service [Axis]
Fair Value by Liability Class [Domain]
Document Fiscal Period Focus
Document Fiscal Period Focus
Document Fiscal Period Focus
Entity Shell Company
Entity Shell Company
Entity Shell Company
Temporary Equity, Ending Balance, Shares
Temporary Equity, Beginning Balance, Shares
Shares Issued and Outstanding
Temporary Equity, Shares Outstanding
Temporary Equity, Shares Outstanding
Other Accrued Liabilities, Current
Other accrued expenses and other current liabilities
Other accrued expenses and other current liabilities
Segments
Segment Reporting, Policy [Policy Text Block]
Segmen tReporting Policy Policy TextBlock
Cash and Cash Equivalents, at Carrying Value, Total
Cash and Cash Equivalent
Cash and cash equivalents, end of period
Cash and cash equivalents, beginning of period
Cash and cash equivalents
Cash equivalents, amortized cost
Other adjustments [Member]
Other adjustments [Member]
Other adjustments [Member]
Cybersecurity Risk Management, Strategy, and Governance [Abstract]
Common Stock, Shares, Issued, Total
Common Stock, Shares, Issued
Common Stock, Shares, Issued
Share Purchased
Cybersecurity Risk Management Positions or Committees Responsible Report to Board [Flag]
Cybersecurity Risk Board of Directors Oversight [Text Block]
Asset Class [Domain]
Asset Class
Statement [Table]
Statement [Table]
Statement [Table]
Proceeds from redeemable convertible preferred stock
Proceeds from issuance of Series B redeemable convertible preferred shares, net of issuance costs
Proceeds from Issuance of Redeemable Convertible Preferred Stock
Country Of Domicile [Member]
Geographic Basis, Country of Domicile [Member]
Unrecognized Tax Benefits, Increase Resulting from Current Period Tax Positions
Additions based on tax positions related to current year
Accounts Receivable, Credit Losses
Accounts Receivable, Credit Losses
Accounts receivable, credit losses
Disclosure of redeemable non-controlling interest.
Redeemable Non Controlling Interest [Text Block]
Redeemable Noncontrolling Interest
Weighted-average grant date fair value of options granted
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Grants in Period, Weighted Average Grant Date Fair Value
Granted
Statement [Line Items]
Statement [Line Items]
Statement [Line Items]
Revenue from Contract with Customer [Policy Text Block]
Revenue Recognition
Entity Filer Category
Entity Filer Category
Entity Filer Category
Liabilities and Equity
Total liabilities and stockholders' equity
Payables and Accruals [Abstract]
Milestone Achievement [Member]
Milestone Achievement.
Milestone Achievement [Member]
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Weighted Average Exercise Price
Exercisable at December 31, 2025
Upfront of cash payment
Upfront of Cash Payment.
upfront of cash payment
Upfront of cash payment
License Agreement Related Payments
License Agreement Related Payments
License agreement related payments
Incremental Common Shares Attributable to Dilutive Effect of Conversion of Preferred Stock
Incremental stock compensation expense
Valuation Allowance, Deferred Tax Asset, Increase (Decrease), Amount
Increases recorded to income tax provision
Increase in Valuation Allowance
Operating Loss Carryforwards [Table]
Operating Loss Carryforwards [Table]
Aggregate Of Upfront License Fee Received
Aggregate Of Upfront License Fee Received
Aggregate Of Upfront License Fee Received
Cybersecurity Risk Third Party Oversight and Identification Processes [Flag]
Cash and Cash Equivalents, Fair Value Disclosure
Cash and cash equivalents, fair value disclosure
Money market funds, included in cash and cash equivalents
Valuation allowance as of end of year
Valuation allowance as of beginning of year
Less: valuation allowance
Less: valuation allowance
Deferred Tax Assets, Valuation Allowance
Less: valuation allowance
Lease For Corporate Office Facility Member
Lease For Corporate Office Facility [Member]
Lease For Corporate Office Facility
Effective Income Tax Rate Reconciliation, at Federal Statutory Income Tax Rate, Percent
Federal Statutory Income Tax Rate Reconciliation, Percent
U.S. federal statutory tax rate
Subsequent Event [Line Items]
Going Concern
Going Concern [Policy TextBlock]
Going Concern [Policy TextBlock]
Cybersecurity Risk Management Third Party Engaged [Flag]
Documents Incorporated by Reference [Text Block]
Documents Incorporated by Reference
Royalty fee payable.
Royalty Fee Payable
Royalty fee payable
Effective tax rate
Effective Income Tax Rate Reconciliation, Percent
Effective Income Tax Rate Reconciliation, Percent, Total
Share-based Payment Arrangement, Option
Income Tax Jurisdiction [Axis]
Income Tax Authority
Takeda Asset Agreement.
Takeda Asset Agreement [Member]
Takeda Asset Agreement [Member]
Geographical [Domain]
Geographical
Inventory, Finished Goods, Gross
Finished goods
Summary of Inventory
Schedule of Inventory, Current [Table Text Block]
Schedule of Performance Stock Options Assumptions
Schedule of Performance Stock Options Assumptions table text block
Schedule of Performance Stock Options Assumptions [Table Text Block]
Schedule of Performance Stock Options Assumptions
Defined Contribution Plan
Defined Contribution Plan [Text Block]
Payments for Repurchase of Private Placement
Payment to private placement
Summary of Significant Accounting Policies
Significant Accounting Policies [Text Block]
Summary of Significant Accounting Policies
Finite-Lived Intangible Asset, Useful Life
Intangible asset useful life
Uncertain Tax Positions
Uncertain Tax Positions
Uncertain tax positions
Cash paid
Aggregate Cash Paid
Aggregate Cash Paid
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Grants in Period, Gross
Granted
Share based compensation by share based payment arrangement non vested options granted during the period
Cybersecurity Risk Management, Strategy, and Governance [Table]
Schedule of Earnings Per Share, Basic and Diluted [Table Text Block]
Summary of Basic and Diluted Net Loss Per Share Attributable to Common Shareholders/Stockholders
Property, Plant and Equipment, Net [Abstract]
Available For Sale Securities Continuous Unrealized Loss Position More Than Twelve Months Fair Value
Available For Sale Securities Continuous Unrealized Loss Position More Than Twelve Months Fair Value
Unrealized losses 12 months or greater fair value
Nontaxable or nondeductible items
Effective Income Tax Rate Reconciliation, Nondeductible Expense, Amount [Abstract]
Earnings Per Share, Basic, Total
Earnings Per Share, Basic
Net loss per share, basic
Net loss per share - basic
Weighted-average vesting term of the award
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Outstanding, Weighted Average Remaining Term
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Outstanding, Weighted Average Remaining Term
Investment Agreement [Member]
Investment Agreement [Member]
Investment Agreement [Member]
Number of Shares, Ending Balance
Number of Shares, Beginning Balance
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Number
Schedule of Available-for-Sale Securities Reconciliation [Table Text Block]
Schedule of Maturities of Our Available-for-Sale Marketable Securities
Schedule Of Maturities For Available For Sale Securities Table Text Block
Schedule Of Maturities For Available For Sale Securities Table Text Block
Schedule Of Maturities For Available For Sale Securities
Additional milestone payments
Additional Milestone Payments
Additional milestone payments
DOT -1 [Member]
DOT One [Member]
DOT One.
Liabilities, Current
Total current liabilities
Lessee, Operating Lease, Liability, to be Paid, Year Five
2030
Domestic Tax Jurisdiction [Member]
Federal
Effective Income Tax Rate Reconciliation, Tax Credit, Percent [Abstract]
Tax credits
Orphan drug credit, Amount
Effective Income Tax Rate Reconciliation, Tax Credit, Other, Amount
Orphan drug credit, Amount
Effective Income Tax Rate Reconciliation [Table]
Unrecognized Tax Benefits, Increase Resulting from Prior Period Tax Positions
Additions based on tax positions related to prior year
Equity, Attributable to Parent [Abstract]
Stockholders' equity
Entity Small Business
Entity Small Business
Entity Small Business
XOMA License Agreement
XOMA License Agreement [Member]
XOMA License Agreement [Member]
Deferred Finance Issuance Costs
Deferred Finance Issuance Costs policy.
Deferred Finance Issuance Costs policy text block [Policy Text Block]
Deferred Finance Issuance Costs
Retained Earnings (Accumulated Deficit)
Retained Earnings (Accumulated Deficit), Ending Balance
Retained Earnings (Accumulated Deficit), Beginning Balance
Retained Earnings (Accumulated Deficit), Total
Retained Earnings (Accumulated Deficit)
Accumulated deficit
Deferred Tax Assets, Tax Deferred Expense, Compensation and Benefits, Share-Based Compensation Cost
Share-based compensation
Effective Income Tax Rate Reconciliation, Nondeductible Expense, Changes in Unrecognized Tax Benefits, Percent
Effective Income Tax Rate Reconciliation, Nondeductible Expense, Changes in Unrecognized Tax Benefits, Percent
Changes in unrecognized tax benefits, Percentage
Entity Well-known Seasoned Issuer
Entity Well-known Seasoned Issuer
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Forfeitures in Period
Forfeiture
Forfeiture
Purchase Price Per Share
Sale of Stock, Price Per Share
Merck License Agreement.
Merck License Agreement [Member]
Merck License Agreement [Member]
Summary of Performance Stock Options
Summary of Performance Stock Options
Summary of Performance Stock Options
Share-Based Payment Arrangement [Text Block]
Share-based Compensation
Organization, Consolidation and Presentation of Financial Statements [Abstract]
Accrued Milestone Liability
Accrued Milestone Liability
Accrued milestone liability
Lease Contractual Term [Axis]
Lease Contractual Term
Common Class A [Member]
Common Class A
Lessee, Lease, Description [Line Items]
Lessee Lease Description [Line Items]
Amendment Flag
Amendment Flag
Amendment Flag
Product and Service [Domain]
Effective Income Tax Rate Reconciliation at Federal Statutory Income Tax Rate, Amount
U.S. federal statutory tax rate, Amount
Inventory
Inventory Disclosure [Text Block]
Available For Sale Securitie Continuous Unrealized Loss Position Less Than Twelve Months Fair Value
Available For Sale Securitie Continuous Unrealized Loss Position Less Than Twelve Months Fair Value
Unrealized Losses Less Than 12 Months, Fair value
Net Loss per Share
Earnings Per Share, Policy [Policy Text Block]
Research And Development Agreements [Member]
Research And Development Agreements Member
Research And Development Agreements [Member]
Liabilities and Equity [Abstract]
Liabilities and stockholders' equity
Entity Address, Postal Zip Code
Entity Address, Postal Zip Code
Entity Address, Postal Zip Code
Accounts Receivable [Policy Text Block]
Accounts Receivable, Net
NORTH CAROLINA
North Carolina
Common Stock [Member]
Common Stock [Member]
Common Stock [Member]
Cybersecurity Risk Role of Management [Text Block]
Granted
Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Grants in Period, Weighted Average Exercise Price
Lessee, Operating Lease, Liability, to be Paid, Year Three
2028
Unamortized stock-based compensation for stock options
Unamortized stock-based compensation for stock options
Unamortized stock-based compensation for stock options
Temporary Equity Related Tranche Liability [Member]
Temporary Equity Related Tranche Liability.
Temporary Equity Related Tranche Liability [Member]
Income Tax Paid, by Individual Jurisdiction [Line Items]
Nasdaq Stock Market [Member]
Nasdaq Stock Market [Member]
Nasdaq Stock Market
Entity Address, Address Line One
Entity Address, Address Line One
Entity Address, Address Line One
Total deferred tax liabilities
Total deferred tax liabilities
Deferred Tax Liabilities, Gross
Total deferred tax liabilities
Schedule of Share-Based Payment Award, Stock Options, Valuation Assumptions [Table Text Block]
Summary of Fair Value of The Incentive Shares Estimated Using An Option Pricing Model
Fair Value Hierarchy and NAV [Axis]
Fair Value Hierarchy and NAV
Unvested common shares
Unvested common shares.
Unvested Common Shares [Member]
Unvested common shares [Member]
Earnings Per Share [Abstract]
Debt Securities, Available-for-Sale, Maturity, Allocated and Single Maturity Date, Amortized Cost, Total
Debt Securities, Available-for-Sale, Maturity, Allocated and Single Maturity Date, Amortized Cost
Amortized Cost, Total
Income Taxes
Income Tax, Policy [Policy Text Block]
Loss Contingency Accrual, Ending Balance
Loss Contingency Accrual, Beginning Balance
Loss Contingency Accrual
Termination and cancellation charges payable
Litigation amount awarded from other party
Cybersecurity Risk Materially Affected or Reasonably Likely to Materially Affect Registrant [Flag]
Cash equivalents, unrealized gains
Cash Equivalents, Unrealized Gains
Cash Equivalents Unrealized Gains
Redeemable Convertible Preferred Shares
Stockholders' Equity Note, Redeemable Preferred Stock, Issue, Policy [Policy Text Block]
State tax credits
Deferred Tax Assets, State Taxes
Samuel Blackman [Member]
Samuel Blackman [Member]
Samuel Blackman [Member]
Operating Lease, Right-of-Use Asset
Operating lease right-of-use asset
Deferred Tax Assets, Gross
Total deferred tax assets
Cybersecurity Risk Board Committee or Subcommittee Responsible for Oversight [Text Block]
Common Shares Purchase Agreement.
Common Shares Purchase Agreement [Member]
Common Shares Purchase Agreement
Inventory Disclosure [Abstract]
Class of Warrant or Right [Axis]
Document Type
Document Type
Document Type
Two Customer [Member]
Two Customer [Member]
Two Customer
Income Taxes Paid, Net
Income Taxes Paid
Collaborative Arrangement and Arrangement Other than Collaborative [Axis]
Collaborative Arrangement and Arrangement Other than Collaborative
Collaborative Arrangement and Arrangement Other than Collaborative [Domain]
Collaborative Arrangement and Arrangement Other than Collaborative
Entity Central Index Key
Entity Central Index Key
Entity Central Index Key
Cybersecurity Risk Process for Informing Board Committee or Subcommittee Responsible for Oversight [Text Block]
Emerging Growth Company Status
Emerging Growth Company Status Policy Text Block
Emerging Growth Company Status Policy Text Block
Valuation Approach and Technique [Axis]
Subsequent Event Type [Domain]
Antidilutive Securities Excluded from Computation of Earnings Per Share, Amount
Stock options
Restricted stock units
Balance Sheet Related Disclosures [Abstract]
Common stock par or stated value per share
Common Stock, Par or Stated Value Per Share
Common Stock, Par or Stated Value Per Share
Security Deposit
Security deposit
Proceeds from Issuance of Warrants
Proceeds from issuance of prefunded warrants to purchase common stock in connection with private placement, net of issuance costs
Proceeds from issuance of prefunded warrants to purchase common stock, net of issuance costs
Operating Lease, Right-of-Use Asset, Periodic Reduction
Amortization of operating right-of-use asset
Amortization of operating right-of-use asset
Amortization of operating right-of-use assets
Weighted average remaining contractual term
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Remaining Contractual Term
Weighted-Average Remaining Contractual Term, Outstanding at December 31, 2025
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Volatility Rate, Maximum
Expected volatility
Debt Securities, Available-for-Sale, Amortized Cost, Total
Debt Securities, Available-for-Sale, Amortized Cost
Debt Securities, Available-for-Sale, Amortized Cost
Debt Securities, Available-for-Sale, Total
Debt Securities, Available-for-Sale
Debt Securities, Available-for-Sale
Indemnification Agreement [Member]
Indemnification Agreement [Member]
Realized Investment Gains (Losses)
Realized Investment Gains (Losses), Total
Realized Investment Gains Losses
Document Financial Statement Error Correction [Flag]
Document Financial Statement Error Correction [Flag]
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercises in Period
Exercised
Issuance of common stock upon exercise of stock options, shares
Exercised
Number of Shares, Ending Balance
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Nonvested, Number of Shares
Unvested restricted stock units at December 31, 2023
Unvested restricted stock units at December 31, 2023
Unvested restricted stock units at December 31, 2024
Other Prepaid Expense, Current
Other prepaid expenses and other assets
Other prepaid expenses and other assets
Temporary equity issue price per share.
Temporary Equity Issue Price Per Share
Temporary Equity Issue Price Per Share
Temporary equity stock issued during the period shares new issues.
Temporary Equity Stock Issued During The Period Shares New Issues
Temporary Equity Stock Issued During The Period Shares New Issues
Black-Scholes option-pricing model
Valuation Technique, Black-Scholes-Merton Model [Member]
State and Local Income Tax
State and Local Income Tax Expense (Benefit), Continuing Operations
Effective Income Tax Rate Total
Effective Income Tax Rate Total
Total
Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Line Items]
Employee Service Share Based Compensation Allocation Of Recognized Period Costs [Line Items]
Ownership [Domain]
Current Fiscal Year End Date
Current Fiscal Year End Date
Current Fiscal Year End Date
Class Of Stock Sub.
Class of Stock Sub [Axis]
Class Of Stock Sub
Employee related expenses
Employee Related Expenses
Employee Related Expenses
Incentive Shares [Member]
Incentive shares.
Incentive Shares [Member]
Incentive Shares [Member]
Series B Redeemable Convertible Preferred Shares.
Series B redeemable convertible preferred shares [Member]
Series B Redeemable Convertible Preferred Shares
Viracta License Agreement Member
Viracta License Agreement [Member]
Viracta License Agreement
License Agreement Milestone Payment
State and local income taxes, net of federal income tax effect
Effective Income Tax Rate Reconciliation, State and Local Income Tax, Amount
Effective Income Tax Rate Reconciliation, State and Local Income Tax, Amount
Entity Address, State or Province
Entity Address, State or Province
Entity Address, State or Province
Number of Share Outstanding, Beginning balance
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Number
Unvested restricted stock units at December 31, 2024
Unvested restricted stock units at December 31, 2024
Unvested restricted stock units at December 31, 2025
Issuance of Series B redeemable convertible preferred shares for cash, net of issuance costs of $243, Value
Stock Issued During Period, Value, Conversion of Convertible Securities
Redeemable Noncontrolling Interest [Line Items]
Comprehensive Income (Loss), Net of Tax, Attributable to Parent
Total comprehensive loss
Total comprehensive loss
Research and Development Expenses
Research and Development Expense, Policy [Policy Text Block]
Common Stock, Capital Shares Reserved for Future Issuance
Common Stock, capital shares purchase an additional for future issuance
Class of Warrant or Right [Domain]
Geographical
Geographical [Axis]
Accounts Receivable [Member]
Accounts Receivable
Inventory, Raw Materials, Gross
Raw materials
Effective Income Tax Rate Reconciliation, State and Local Income Taxes, Amount
State and local income taxes, net of federal income tax effect, Amount
License [Member]
License revenue [Member]
License revenue [Member]
Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Table Text Block]
Summary of Share-based Compensation Expense Recorded in The Accompanying Condensed Consolidated Statements of Operations and Comprehensive Loss
Other adjustments, Amount
Effective Income Tax Rate Reconciliation, Nondeductible Expense, Other, Amount
Available For Sale Securitie Continuous Unrealized Loss Position Fair Value
Available For Sale Securitie Continuous Unrealized Loss Position Fair Value
Fair Value
Stock Issued During Period, Value, Stock Options Exercised
Issuance of common stock upon exercise of stock options, Amount
Comprehensive Loss
Comprehensive Income, Policy [Policy Text Block]
Schedule of Deferred Tax Assets and Liabilities [Table Text Block]
Schedule of Deferred Tax Assets and Liabilities
Collaborative Arrangement Disclosure [Text Block]
Significant Agreements
Third-Party CRO, CMO and Other Third-Party Clinical Trial Costs
Third-Party CRO, CMO and Other Third-Party Clinical Trial Costs
Third-party CRO, CMO and other third-party clinical trial costs
Subsequent Event [Member]
Subsequent Event [Member]
Concentration of Credit Risk and Other Risks and Uncertainties [Member]
Concentration of Credit Risk and Other Risks and Uncertainties [Member]
Concentration Of Credit Risk And Other Risks And Uncertainties
Accrued Research and Development Expenses.
Accrued research and development expenses
Accrued research and development expenses
Deferred revenue, current
Deferred Revenue, Current
Deferred Revenue, Current, Total
Current portion of deferred revenue
Deferred Tax Assets, Tax Credit Carryforwards, Research
Capitalized R&D Section 174 Expense
Option Repricing [Member]
Option Repricing [Member]
Option Repricing
Antidilutive Securities [Axis]
Antidilutive Securities
Operating Loss Carryforwards [Line Items]
Operating Loss Carryforwards [Line Items]
External costs:
External Costs [Abstract]
External Costs [Abstract]
Total fair value of options
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Outstanding, Aggregate Intrinsic Value
common stock to be issued under the ESPP Table text block
common stock to be issued under the ESPP Table text block
Common stock to be issued under the ESPP Table text block
Purchase Commitment, Excluding Long-Term Commitment [Axis]
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Abstract]
State and Local Jurisdiction [Member]
State
Related Party Transaction [Axis]
Customer [Domain]
Unrecognized Tax Benefits, Decrease Resulting from Current Period Tax Positions
Reductions based on tax positions related to current year
Cash equivalents, unrealized losses
Cash Equivalents, Unrealized Losses
Cash Equivalents Unrealized Losses
Finite-Lived Intangible Asset, Expected Amortization, after Year Five
Thereafter
Carrying value
Redeemable Noncontrolling Interest, Equity, Preferred, Carrying Amount
Redeemable convertible preferred shares, no par value; no shares authorized, issued and outstanding at December 31, 2021; 22,851,257 shares authorized, issued and outstanding at December 31, 2020
Revenue Recognition, Milestone Method, Revenue Recognized
Milestone payment received
Deferred Income Tax Expense (Benefit), Continuing Operations [Abstract]
Deferred
Common stock shares issued as a result of conversion of temporary equity into permanent equity.
Common Stock Shares Issued As A Result Of Conversion Of Temporary Equity Into Permanent Equity
Common Stock Shares Issued As A Result Of Conversion Of Temporary Equity Into Permanent Equity
Minimum [Member]
Minimum
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Grants in Period, Weighted Average Grant Date Fair Value
Grant date fair value
Weighted Average Grant Date Fair Value, Granted
Financial Instrument [Axis]
Assets, Current [Abstract]
Current assets:
License Agreement Milestone Payment [Member]
License Agreement Milestone Payment [Member]
License agreement milestone payment [Member]
Amortization of Intangible Assets
Amortization of intangible assets
Amortization Of Intangible Assets
Common Class B [Member]
Common Class B
Fair Value, Inputs, Level 3 [Member]
Fair Value, Inputs, Level 3
Two thousand and twenty one stock incentive plan.
2021 Stock Incentive Plan [Member]
Two Thousand And Twenty One Stock Incentive Plan
Segment Reporting [Abstract]
Schedule of Fair Value, Assets and Liabilities Measured on Recurring Basis [Table Text Block]
Schedule of Fair Value, Assets and Liabilities Measured on Recurring Basis
Schedule of fair value, assets and liabilities measured on recurring basis
Liabilities, Current [Abstract]
Current liabilities:
Product [Member]
Product revenue, net [Member]
Ipsen License Agreement [Member]
Ipsen License Agreement [Member]
Ipsen License Agreement
Volume Weighted Average Price
Volume Weighted Average Price
Volume weighted average price
Sprint Bioscience Agreement [Member]
Sprint Bioscience Agreement [Member]
Sprint Bioscience Agreement [Member]
Other
Deferred Tax Assets, Tax Deferred Expense, Reserves and Accruals, Accrued Liabilities
Operating Loss Carryforwards
Operating Loss Carryforwards
Net operating loss carryforwards
Income Tax Paid, by Individual Jurisdiction [Abstract]
Commitments and Contingencies
Commitments and contingencies (Note 8)
Lessee, Leases [Policy Text Block]
Leases
Central America [Member]
Central America
Weighted Average Grant Date Fair Value, Ending Balance
Weighted Average Grant Date Fair Value, Beginning Balance
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Weighted Average Grant Date Fair Value
Unvested restricted stock units at December 31, 2023
Unvested restricted stock units at December 31, 2024
Inventory, Work in Process, Gross
Work-in-process
General and Administrative Expense [Member]
General and Administrative Expense
Present value of operating lease liabilities
Operating Lease, Liability, Total
Operating Lease, Liability
Temporary equity shares converted into permanent equity
Temporary Equity Shares Converted Into Permanent Equity
Temporary equity shares converted into permanent equity.
Auditor Firm ID
Other Individual Customer
Other Individual Customer [Member]
Other Individual Customer [Member]
Obligations [Member]
Obligations
Concentration Risk Benchmark [Axis]
Lessee, Lease, Description [Table]
Lessee Lease Description [Table]
Change in valuation allowance
Effective Income Tax Rate Reconciliation, Change in Deferred Tax Assets Valuation Allowance, Percent
Lease Contractual Term [Domain]
Lease Contractual Term
Gross state NOL
Deferred Tax Assets, Other Loss Carryforwards
Cybersecurity Risk Management Positions or Committees Responsible [Text Block]
Weighted Average Number of Shares Outstanding, Basic, Total
Weighted Average Number of Shares Outstanding, Basic
Weighted-average number of common shares used in computing net loss per share, basic
Weighted average shares outstanding - basic
Prepaid Expenses and Other Current Asset
Prepaid Expenses and Other Current Asset.
Prepaid Expenses and Other Current Asset [Text Block]
Prepaid Expenses and Other Current Assets
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Intrinsic Value
Exercisable at September 30, 2023, Aggregate Intrinsic Value
Exercisable at September 30, 2025
Exercisable at December 31, 2025, Aggregiate Intrinsic Value
Schedule of Effective Income Tax Rate Reconciliation [Table Text Block]
Schedule of Effective Income Tax Rate Reconciliation
Two Thousand Twenty One Employee Stock Purchase Plan [Member]
Two Thousand Twenty One Employee Stock Purchase Plan [Member]
Two Thousand Twenty One Employee Stock Purchase Plan
Schedule of Share-Based Compensation Arrangements by Share-Based Payment Award [Table]
Schedule Of Share Based Compensation Arrangements By Share Based Payment Award [Table]
Cybersecurity Risk Process for Informing Management or Committees Responsible [Text Block]
Proceeds from Issuance of Private Placement
Proceeds from issuance of common stock in connection with private placement, net of placement agent fees and offering costs
Proceeds from issuance of private placement
Deferred Tax Assets, Net [Abstract]
Deferred tax assets
Deposit Contracts, Policy [Policy Text Block]
Deposits
Subsequent Events
Subsequent Events [Text Block]
Effective Income Tax Rate Reconciliation, Tax Credit, Percent
Effective Income Tax Rate Reconciliation, Tax Credit, Percent, Total
Credits
Accrued federal and state payables
Accrued federal and state payables
Accrued federal and state payables
Effective Income Tax Rate Reconciliation, Change in Deferred Tax Assets Valuation Allowance, Amount
Change in deferred tax assets valuation allowance
Changes in valuation allowances, Amount
Beginning Balance
Equity, Attributable to Parent
Ending Balance
Total stockholders' equity
Basis of Accounting, Policy [Policy Text Block]
Basis of Presentation
Basis of Presentation
Schedule Of Common Stock Shares Reserved For Future Issuance Table Text Block
Schedule Of Common Stock Shares Reserved For Future Issuance [Table Text Block]
Schedule of Common Stock Shares Reserved for Future Issuance
Weighted Average Price of Company's common Stock
Weighted Average Price of Company's common Stock
Weighted Average Price of Company's common Stock
Redeemable Noncontrolling Interest [Table]
Cost of Product Revenue
Cost of Goods and Service [Policy Text Block]
CVR Agreement [Member]
CVR Agreement [Member]
CVR Agreement [Member]
Valuation Approach and Technique [Domain]
Cash Equivalents [Member]
Cash Equivalents [Member]
Use of Estimates
Use of Estimates, Policy [Policy Text Block]
Use of Estimates
Share-based compensation
Effective Income Tax Rate Share based compensation
Effective Income Tax Rate Share based compensation
Schedule of Nonvested Share Activity
Schedule of Nonvested Share Activity [Table Text Block]
Defined Contribution Plan, Number of Employees
Number Of Employees
Deposits and other long-term assets Non current.
Deposits and other longterm assets Non current
Deposits and other long-term assets
Equity Investment
Equity Method Investment, Underlying Equity in Net Assets
Upfront payment
Upfront payment.
Upfront Payment
Upfront payment
Entity Address, Address Line Two
Entity Address, Address Line Two
Entity Address, Address Line Two
Fair Value Disclosures [Text Block]
Recurring Fair Value Measurements
Milestone payments not yet paid
Milestone payments not yet paid
Milestone payments not yet paid
Disclosure of Share-Based Compensation Arrangements by Share-Based Payment Award [Table Text Block]
Summary of Stock Option Activity
Accelerated Share Repurchases, Initial Price Paid Per Share
Price Per Target Share
Brisbane California
Brisbane, California [Member]
Brisbane, California [Member]
Accrued Liabilities and Other Liabilities, Total
Accrued Liabilities and Other Liabilities
Accrued expenses and other current liabilities
Summary of Unrecognized Tax Benefits
Schedule of Unrecognized Tax Benefits Roll Forward [Table Text Block]
License agreement with Ipsen Pharma SAS [Member]
License agreement with Ipsen Pharma SAS [Member]
License agreement with Ipsen Pharma SAS [Member]
Available For Sale Securitie Continuous Unrealized Loss Position Accumulated Loss
Available For Sale Securitie Continuous Unrealized Loss Position Accumulated Loss
Unrealized losses
Plan Name [Domain]
Plan Name
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items]
Cybersecurity Risk Materially Affected or Reasonably Likely to Materially Affect Registrant [Text Block]
Reclassifications
Reclassifications [Text Block]
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Exercisable, Weighted Average Exercise Price
Vested and expected to vest at December 31, 2025
Current State and Local Tax Expense (Benefit)
Tax Credit Carryforward, Expiration Year
State and local
Cybersecurity Risk Management Expertise of Management Responsible [Text Block]
Number of Pre-funded warrants purchased
Class of Warrant or Right, Outstanding
Related and Nonrelated Parties [Axis]
Related Party
Pre-Funded Warrant [Member]
Pre-Funded Warrant [Member]
Pre-Funded Warrant [Member]
Foreign Tax Jurisdiction [Member]
Foreign
Property and Equipment, Net
Property, Plant and Equipment, Policy [Policy Text Block]
Entity Address, City or Town
Entity Address, City or Town
Entity Address, City or Town
Number of Reportable Segments
Number of reportable segment
Security Exchange Name
Security Exchange Name
Security Exchange Name
Intangible assets, net
Indefinite-Lived Intangible Assets (Excluding Goodwill)
Indefinite-Lived Intangible Assets (Excluding Goodwill), Ending Balance
Indefinite-Lived Intangible Assets (Excluding Goodwill), Beginning Balance
Indefinite-Lived Intangible Assets (Excluding Goodwill), Total
Temporary Equity [Text Block]
Redeemable Convertible Preferred Shares
Temporary Equity [Text Block].
Temporary Equity [Table Text Block]
Redeemable Convertible Preferred Shares
Intangible Assets Disclosure [Text Block]
Intangible Assets
Details Domain
Details [Domain]
Details
Concentration Risk Type [Domain]
Accrued Royalties, Current
Accrued royalties
Antidilutive Securities, Name [Domain]
Antidilutive Securities, Name
Permanent items
Permanent differences
Effective Income Tax Rate Reconciliation, Foreign Income Tax Rate Differential, Percent
Stock Option Exercise Price
Stock Option, Exercise Price, Decrease
Stockholders' Equity Note [Abstract]
Inventory, Net
Inventory, Net, Total
Inventory
Intangible asset basis
Deferred Tax Assets, Goodwill and Intangible Assets
Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Table]
Schedule Of Employee Service Share Based Compensation Allocation Of Recognized Period Costs [Table]
Statistical Measurement [Domain]
Statistical Measurement
Cost of Product Revenue
Cost of Product Revenue
Cost of product revenue
Class of Warrant or Right, Exercise Price of Warrants or Rights
Excersise price of pre-funded warrants
Exercise price per share
Assets, Current
Total current assets
Share-Based Payment Arrangement, Expense
Share-based compensation expense
Share-based compensation expense
Document Period End Date
Document Period End Date
Document Period End Date
Charles York [Member]
Charles York [Member]
Charles York [Member]
Fair Value Hierarchy and NAV [Domain]
Fair Value Hierarchy and NAV
ICFR Auditor Attestation Flag
ICFR Auditor Attestation Flag
Individual Customer [Member]
Individual Customer [Member]
Individual Customer
Balance Sheet Items [Lines items]
Balance Sheet Items Lines items
Statement of Financial Position [Abstract]
Restricted Stock Units (RSUs) [Member]
Restricted Stock Units (RSUs) [Member]
Restricted Stock Units (RSUs)
Redeemable convertible preferred shares
Redeemable Convertible Preferred Stock [Member]
Redeemable Convertible Preferred Stock [Member]
Antidilutive Security, Excluded EPS Calculation [Table]
Schedule Of Antidilutive Securities Excluded From Computation Of Earnings Per Share [Table]
Class of Stock [Axis]
Class of Stock
Class of Stock [Axis]
Accrued Research and Development Expenses
In Process Research and Development, Policy [Policy Text Block]
Details Axis
Details [Axis]
Details
Current Income Tax Expense (Benefit)
Total current
Total current
Cybersecurity Risk Management, Strategy, and Governance [Line Items]
Liabilities
Total liabilities
Unrecognized Tax Benefits More Likely Than NotThreshold Percentage
Unrecognized Tax Benefits More Likely Than NotThreshold Percentage
Unrecognized Tax Benefits More Likely Than Not Threshold Percentage
Tenant Improvements
Tenant improvement allowances receivable
Financial Instruments [Domain]
Income (Loss) Attributable to Parent, before Tax
Loss before income taxes
Increase (Decrease) in Deferred Revenue
Deferred revenue
Marketable securities [Member]
Marketable securities [Member]
Marketable Securities [Member]
Incremental Shares Reserved For Future Issuance.
Incremental Shares Reserved For Future Issuance [Member]
Incremental Shares Reserved For Future Issuance
Lessee, Operating Lease, Liability, to be Paid, Year Two
2027
Restricted Stock [Member]
Restricted Stock
NEW YORK
New York
Indefinite-Lived Intangible Assets, Major Class Name [Domain]
Prepaid Expense and Other Assets, Current [Abstract]
Schedule of Stock Options Assumptions
Schedule of Stock Options Assumptions
Schedule of Stock Options Assumptions [Table Text Block]
Schedule of Stock Options Assumptions.
Finite-Lived Intangible Assets, Gross
Finite-Lived Intangible Assets, Gross, Total
Intangible assets, gross
Illinois
ILLINOIS
Debt Securities, Available-for-Sale, Continuous Unrealized Loss Position, Less than 12 Months, Accumulated Loss
Debt Securities, Available-for-Sale, Continuous Unrealized Loss Position, Less than 12 Months, Accumulated Loss
Stock Issued During Period, Shares, Employee Stock Ownership Plan
Stock Issued During Period, Shares, Employee Stock Ownership Plan
Weighted Average Number of Shares Outstanding, Diluted
Weighted Average Number of Common Shares Used In Computing Net Loss Per Share, Basic And Diluted
Weighted-average number of common shares used in computing net loss per share, diluted
Weighted average shares outstanding - diluted
Entity File Number
Entity File Number
Entity File Number
Cover
Cover [Abstract]
Cover [Abstract]
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Volatility Rate, Minimum
Expected volatility
Other Expenses
Other expenses
Adjustment to additional paid in capital loss on conversion of temporary equity into permanent equity
Adjustment To Additional Paid In Capital Loss On Conversion Of Temporary Equity Into Permanent Equity
Adjustment to additional paid in capital loss on conversion of temporary equity into permanent equity.
Recent Accounting Guidance.
Recent Accounting Guidance [Text Block]
Recent Accounting Guidance
Total prepaid expenses and other current assets
Prepaid Expense and Other Assets, Current
Prepaid expenses and other current assets
Total prepaid expenses and other current assets
Forfeiture
Forfeited
Conversion of incentive shares
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Forfeited in Period
PRV Related Obligation, Amount
PRV Related Obligation, Amount
PRV Related Obligation, Amount
Share-Based Compensation Arrangement by Share-Based Payment Award, Percentage of Outstanding Stock Maximum
Share-based Compensation Arrangement by Share-based Payment Award, Percentage of Outstanding Stock Maximum
Balance Sheet Items
Supplemental Balance Sheet Disclosures [Text Block]
Derivative, Gain (Loss) on Derivative, Net, Total
Derivative, Gain (Loss) on Derivative, Net
Derivative, Gain (Loss) on Derivative, Net
Shares committed under ESPP
Shares Committed Under E S P P [Member]
Shares Committed Under E S P P.
Revenue Benchmark [Member]
Sales Revenue Net
US Treasury Securities [Member]
US Treasury Securities [Member]
Fair Value, Liabilities Measured on Recurring and Nonrecurring Basis [Table Text Block]
Schedule of Cash Equivalents, Marketable Securities, and Unrealized Gains and Losses
Number of operating segment
Number of Operating Segments
Sale of Stock [Domain]
Sale of Stock
Segment Reporting
Segment Reporting Disclosure [Text Block]
General and Administrative Expense, Total
General and Administrative Expense
Selling, general and administrative
Gain on Sale of Investments
Gain from sale of priority review voucher
Gain from sale of priority review voucher
Liquidation Value
Temporary Equity, Liquidation Preference
Share-based compensation arrangement by share-based payment award, options, vested, number of shares
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested, Number of Shares
Vested and expected to vest at December 31, 2025
Subsequent Event [Table]
Purchase Commitment, Remaining Minimum Amount Committed
Purchase Commitment, Remaining Minimum Amount Committed
Finite-Lived Intangible Assets, Net
Finite-Lived Intangible Assets, Net, Ending Balance
Finite-Lived Intangible Assets, Net, Beginning Balance
Unamortized finite-lived intangible asset
Total future expected amortization expense
Incremental stock compensation expense
Employee Stock Ownership Plan (ESOP), Compensation Expense
Accrued milestone payment
Accrued Milestone Payment
Accrued Milestone Payment
Leases
Lessor, Leases [Policy Text Block]
Undelivered Relapsed or Refractory, Front-Line and Companion Diagnostic Research and Development Services [Member]
Undelivered Relapsed or Refractory, Front-Line and Companion Diagnostic Research and Development Services [Member]
Undelivered Relapsed or Refractory, Front-Line and Companion Diagnostic Research and Development Services [Member]
Recently Issued Accounting Pronouncements
New Accounting Pronouncements, Policy [Policy Text Block]
Lessee, Operating Lease, Liability, to be Paid, Maturity [Table Text Block]
Summary of Future Lease Obligations
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]
Antidilutive Securities Excluded From Computation Of Earnings Per Share [Line Items]
Issuance of Series B redeemable convertible preferred shares for cash, net of issuance costs of $243, Shares
Issuance of redeemable convertible preferred shares
Stock Issued During Period, Shares, Conversion of Convertible Securities
Other adjustments, Percentage
Effective Income Tax Rate Reconciliation, Nondeductible Expense, Other, Percent
Ownership [Axis]
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Risk Free Interest Rate, Minimum
Risk-free interest rate
Depreciation
Depreciation, Total
Lessee, Operating Lease, Term of Contract
Operating lease term
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Dividend Payments
Share-based compensation arrangement by share-based payment award, fair value assumptions, expected dividend payments
Share-based compensation arrangement by share-based payment award, fair value assumptions, expected dividend payments
Common Stock, Shares, Outstanding, Ending Balance
Common Stock, Shares, Outstanding, Beginning Balance
Common Stock, Shares, Outstanding
Common Stock, Shares, Outstanding
Operating Lease, Liability, Current
Current portion of operating lease liabilities
Less : current portion of operating lease liabilities
Less: current portion of operating lease liabilities
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Cybersecurity Risk Management Processes Integrated [Flag]
Document Transition Report
Document Transition Report
Document Transition Report
Net deferred tax assets
Deferred Tax Assets, Net
Short-Term Investments, Total
Short-Term Investments
Short-term investments
Operating Expenses
Total cost and operating expenses
Research And Development Expense
Research and Development Expense
Total research and development expenses
Research and development
Sales agreement member
Sales Agreement [Member]
Sales agreement [Member]
Schedule of Components of Income Tax Expense (Benefit) [Table Text Block]
Summary of Significant Components of the Income Tax Provision From Continuing Operations
Class Of Stock Sub.
Class of Stock Sub [Domain]
Class Of Stock Sub
Federal
Current Federal Tax Expense (Benefit)
Common stock issued in IPO, net of issuance costs
Stock Issued During Period, Value, New Issues
Stock Issued During Period, Value, New Issues
Prepaid research and development expenses
Prepaid Research and Development Expenses.
Prepaid research and development expenses
Prepaid research and development expenses
Effective Income Tax Rate Reconciliation, Nondeductible Expense, Share-Based Payment Arrangement, Percent
Share-based compensation, Percentage
Equity [Text Block]
Common Stock
One Customer [Member]
One Customer [Member]
One Customer
Finite-Lived Intangible Assets [Line Items]
Earnings Per Share [Text Block]
Net Loss Per Share
Temporary Equity [Line Items]
Temporary Equity [Line Items]
Cybersecurity Risk Management Processes Integrated [Text Block]
Net loss
Net loss
Total intrinsic value of the options outstanding
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Intrinsic Value
Outstanding at March 31, 2022, Aggregate Intrinsic Value
Outstanding at December 31, 2025, Aggregiate Intrinsic Value
Inventory [Line Items]
Income Tax Expense (Benefit), Continuing Operations, by Jurisdiction [Abstract]
Current
Aggregate cash consideration paid
Aggregate Cash Consideration Paid.
Aggregate cash consideration paid
Aggregate cash consideration paid
Gross Proceeds [Member]
Gross Proceeds.
Gross Proceeds [Member]
Expected dividend yield
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Dividend Rate
Share based compensation by share based payment award fair value assumptions dividend yield
Operating Lease, Payments
Operating lease payments
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Exercisable, Aggregate Intrinsic Value
Vested and expected to vest at December 31, 2025
Milestone, Cash Payment Received, Per Share
Milestone, Cash Payment Received, Per Share
Milestone, cash payment received
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Risk Free Interest Rate
Risk free rate
Risk-free interest rate
Document Fiscal Year Focus
Document Fiscal Year Focus
Document Fiscal Year Focus
Frontline Payment
Frontline Payment
Frontline Payment
Debt Conversion, Converted Instrument, Shares Issued
Debt Conversion, Converted Instrument, Shares Issued
Concentration Risk Benchmark [Domain]
Purchase Commitment
Purchase Commitment [Member]
Retirement Benefits [Abstract]
Agreement
Agreement Domain
Agreement [Domain]
Accounts Payable, Current, Total
Accounts Payable, Current
Accounts payable
Incremental compensation cost related to vested stock options
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested in Period, Fair Value
Schedule of Income before Income Tax, Domestic and Foreign [Table Text Block]
Schedule of Income taxes paid (net of refunds)
Research and Development Expense [Member]
Research and Development Expense [Member]
Proceeds from Sale of Productive Assets
Proceeds from Sale of Productive Assets, Total
Proceeds from sale of priority review voucher
Proceeds from sale of priority review voucher
Federal
Deferred Federal Income Tax Expense (Benefit)
Finite-Lived Intangible Asset, Expected Amortization, Year One
2026
Schedule of Unvested Restricted Stock Units Roll Forward [Table Text Block]
Summary of The Unvested Common Stock
Summary of Restricted Stock Units Activity
Temporary Equity Disclosure [Abstract]
Net Operating Loss, Carryback period
Net Operating Loss, Carryback period.
Net Operating Loss Carryback Period
Fair Value Disclosures [Abstract]
Commitments and Contingencies Disclosure [Abstract]
Lessee, Operating Lease, Liability, to be Paid, Year One
2026
PRV (Pressure Relief Valve) [Member]
PRV (Pressure relief valve) [Member]
PRV
Net Income (Loss) Attributable to Redeemable Noncontrolling Interest, Total
Net Income (Loss) Attributable to Redeemable Noncontrolling Interest
Net loss attributable to redeemable convertible noncontrolling interests
Derivative Instrument [Axis]
Derivative Instrument
Thereafter
Lessee, Operating Lease, Liability, to be Paid, after Year Five
Share-Based Payment Arrangement [Abstract]
Conditions For Issue Domain
Conditions For Issue [Domain]
Conditions For Issue
Payment Of Obligations To Related Party
Payment Of Obligations To Related Party
Payment of Obligations to Related Party
NonCurrent [Member]
NonCurrent [Member]
Noncurrent
Sale of Stock [Axis]
Sale of Stock
Accrued Payroll Related Expenses
Accrued Payroll Related Expenses
Accrued payroll related expenses
Concentration Risk, Percentage
Concentration risk percentage of net product revenue and accounts receivable
Disclosure details of activities relating to incentive shares.
Disclosure Details Of Activities Relating To Incentive Shares [Table Text Block]
Summary of The Incentive Shares Activity
Revenues
Revenues, Total
Royalty Revenue
Total revenues
Title of 12(b) Security
Title of 12(b) Security
Title of 12(b) Security
Schedule of Segment Reporting Information, by Segment [Table]
InvestmentIncomeNet
Investment Income, Net
Investment Income, Net, Total
Patent Costs
Patent Costs [PolicyTextBlock]
Patent Costs.
Effective Income Tax Rate Reconciliation, Nondeductible Expense, Share-Based Payment Arrangement, Amount
Share-based compensation, Amount
Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Forfeitures in Period, Weighted Average Exercise Price
Forfeiture
Forfeited
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Forfeitures, Weighted Average Grant Date Fair Value
Forfeited
Forfeiture
OCI, Debt Securities, Available-for-Sale, Gain (Loss), before Adjustment, after Tax, Total
OCI, Debt Securities, Available-for-Sale, Gain (Loss), before Adjustment, after Tax
Unrealized (loss) gain on available-for-sale securities
Unrealized gain on available-for-sale securities
Unrealized loss on available-for-sale securities
Unrealized (loss) gain on available-for-sale securities
Money Market Funds [Member]
Money Market Funds [Member]
Related and Nonrelated Parties [Domain]
Related Party
Income Tax Disclosure [Text Block]
Income Taxes
Jeremy Bender [Member]
Jeremy Bender [Member]
Jeremy Bender [Member]
Collaborative Arrangement and Arrangement Other than Collaborative [Table]
Schedule Of Collaborative Arrangements And Noncollaborative Arrangement Transactions [Table]
Two Thousand And Twenty Two Equity Inducement Plan [Member]
Two Thousand And Twenty Two Equity Inducement Plan [Member]
2022 Equity Inducement Plan [Member]
2022 Equity Inducement Plan [Member]
Other long-term liability
Other Liabilities, Noncurrent
Property, Plant and Equipment [Table Text Block]
Schedule of Property and Equipment, Net
Schedule of Property and Equipment
Weighted Average Exercise Price, Ending Balance
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Exercise Price
Weighted Average Exercise Price, Begining Balance
Income Tax Disclosure [Abstract]
Fair Value, Recurring and Nonrecurring [Table]
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Table]
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Unvested in Period, Fair Value
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Unvested in Period, Fair Value
Incremental compensation cost related to unvested stock options
Unrecognized Tax Benefits
Balance at end of year
Balance at beginning of year
Changes in unrecognized tax benefits, Amount
Schedule of Prepaid and Other Current Assets
Schedule Of Prepaid And Other Current Assets.
Schedule Of Prepaid And Other Current Assets [Table Text Block]
Schedule Of Prepaid Expenses and Other Current Assets
Unvested Common Stock.
Unvested Common Stock [Member]
Unvested Common Stock
Measurement Frequency [Domain]
Measurement Frequency
Accrued Rebates
Accrued Rebates
Accrued rebates
Statement of Income Location, Balance [Axis]
Income Statement Location
Trading Symbol
Trading Symbol
Trading Symbol
Cash Payment Against Milestone Achievement
Cash Payment Against Milestone Achievement
Cash payment against milestone achievement
Intangible Asset, Finite-Lived [Table]
Property, Plant and Equipment Disclosure [Text Block]
Property and Equipment, Net
Schedule of Changes in the Valuation Allowance for Deferred Tax Assets
Schedule of Changes in the Valuation Allowance for Deferred Tax Assets
Schedule of Changes in the Valuation Allowance for Deferred Tax Assets
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Risk Free Interest Rate, Maximum
Risk-free interest rate
Debt Securities, Available-for-Sale, Amortized Cost, Maturity, Allocated and Single Maturity Date, Year One
Amortized cost, Mature in one year or less
Subsequent Event Type [Axis]
Cash payment against milestone achievement, per share
Cash Payment Against Milestone Achievement, Per Share
Cash Payment Against Milestone Achievement, Per Share
Schedule of Finite-Lived Intangible Assets [Table Text Block]
Schedule Of Intangible Assets
Series A Redeemable Convertible Preferred Stock [Member]
Series A Redeemable Convertible Preferred Stock.
Series A Redeemable Convertible Preferred Stock [Member]
Expected term (in years)
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Term
Time to liquidity (in years)
Fair Value, Recurring [Member]
Fair Value, Recurring
Accounts Payable and Accrued Liabilities Disclosure [Text Block]
Accrued Expenses and Other Current Liabilities
Entity Ex Transition Period
Entity Ex Transition Period
Entity Ex Transition Period
Total future minimum lease payments
Lessee, Operating Lease, Liability, to be Paid
Total future minimum lease payments
Lessee, Operating Lease, Liability, Undiscounted Excess Amount
Less: Imputed interest
Less: imputed interest
Research and development tax credit, Percentage
Effective Income Tax Rate Reconciliation, Tax Credit, Research, Percent
Research and development tax credit, Percentage
Takeda [Member]
Takeda.
Series B Redeemable Convertible Preferred Stock [Member]
Series B Redeemable Convertible Preferred Stock.
Series B Redeemable Convertible Preferred Stock [Member]
Equity Components [Axis]
Equity Components
Performance Stock Units
Performance Stock Units [Member]
Performance Stock Units Member
Cost of License Revenue
Cost of License Revenue [Policy Text Block]
Cost of License Revenue [Policy Text Block]
Total non-operating income, net
Nonoperating Income (Expense)
Equity Component [Domain]
Equity Component
Asset Class [Axis]
Asset Class
Goodwill and Intangible Assets Disclosure [Abstract]
State
State and Local Tax Jurisdiction, Other [Member]
Deferred Revenue, Noncurrent
Deferred Revenue, Noncurrent, Total
Long-term portion of deferred revenue
Deferred revenue, noncurrent
Document Annual Report
Document Annual Report
Prepaid Insurance
Prepaid insurance
Prepaid insurance
Internal Costs [Abstract]
Internal Costs [Abstract]
Internal costs:
IPO [Member]
IPO [Member]
Customer [Axis]
Maximum [Member]
Maximum
Payment of Milestones
Payment of Milestones.
Payment of Milestones
Payment of Milestones
Statistical Measurement [Axis]
Statistical Measurement
Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Exercises in Period, Weighted Average Exercise Price
Exercised
Finite-Lived Intangible Assets, Accumulated Amortization
Less accumulated amortization
Receivables, Net, Current
Receivables, Net, Current, Total
Accounts receivable, net
Common Stock, Value, Issued, Ending Balance
Common Stock, Value, Issued, Beginning Balance
Common Stock, Value, Issued, Total
Common Stock, Value, Issued
Common Stock Value
Common stock, $0.001 par value; 500,000,000 shares authorized as of December 31, 2025 and December 31, 2024; 102,982,700 and 101,116,162 shares issued and outstanding as of December 31, 2025 and December 31, 2024, respectively
Royalty revenue [Member]
Royalty [Member]
Comprehensive Income (Loss), Net of Tax, Attributable to Parent [Abstract]
Other comprehensive income:
Foundation Medicine
Foundation Medicine, Inc. [Member]
Foundation Medicine, Inc. [Member]
Cybersecurity Risk Management Processes for Assessing, Identifying, and Managing Threats [Text Block]
Impairment or Disposal of Long-Lived Assets, Policy [Policy Text Block]
Impairment of Long-Lived Assets
Cash and Cash Equivalents [Line Items]
Effective Income Tax Rate Reconciliation, State and Local Income Taxes, Percent
State tax
Schedule Of Amortization Expense For Amortizable Finite-Lived Intangible Assets
Schedule of Finite-Lived Intangible Assets, Future Amortization Expense [Table Text Block]
Entity Public Float
Entity Public Float
Volatility
Expected volatility
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Volatility Rate
Pre-Funded Warrants [Member]
Pre-Funded Warrants [Member]
Pre-Funded Warrants [Member]
Available For Sale Securitie Continuous Unrealized Loss Position Less Than 12 Months Accumulated Loss
Available For Sale Securitie Continuous Unrealized Loss Position Less Than 12 Months Accumulated Loss
Unrealized Losses Less Than 12 Months, Unrealized losses
Debt Securities, Available-for-Sale, Maturity, Allocated and Single Maturity Date, Fair Value, Total
Debt Securities, Available-for-Sale, Maturity, Allocated and Single Maturity Date, Fair Value
Fair Value, Total
Entity Registrant Name
Entity Registrant Name
Entity Registrant Name
Unrecognized Tax Benefits, Income Tax Penalties and Interest Accrued
Unrecognized Tax Benefits, Income Tax Penalties and Interest Accrued
Accrued tax-related interest or penalties
Fair Value, Measurement with Unobservable Inputs Reconciliation, Recurring Basis, Asset, Transfers, Net
Fair Value, Measurement with Unobservable Inputs Reconciliation, Recurring Basis, Asset, Transfers, Net
Fair Value, Measurement with Unobservable Inputs Reconciliation, Recurring Basis, Asset, Transfers, Net, Total
Fair value, measurement recurring basis, asset, transfers, net
Entity Voluntary Filers
Entity Voluntary Filers
Finite-Lived Intangible Asset, Expected Amortization, Year Two
2027
Other Nonoperating Income (Expense), Total
Other Nonoperating Income (Expense)
Other (expense) income, net
MRKDG License Agreement [Member]
MRKDG License Agreement [Member]
MRKDG License Agreement [Member]
Additional Paid in Capital, Ending Balance
Additional Paid in Capital, Beginning Balance
Additional Paid in Capital, Total
Additional Paid in Capital
Additional paid-in-capital
Deferred State and Local Income Tax Expense (Benefit)
State and local
Conversion Of Stock Shares Issued1
Conversion of Stock, Shares Issued
Number of shares issued upon conversion
Subsequent Events [Abstract]
Total accrued expenses and other current liabilities
Accounts Payable and Accrued Liabilities, Current
Total accrued expenses and other current liabilities
Number of Shares, Unvasted Restricted Stock, Ending balance
Number of Shares, Unvasted Restricted Stock, Beginning balance
Outstanding as of December 31, 2021
Share based compensation by share based payment arrangement equity instruments other than options outstanding.
Share Based Compensation By Share Based Payment Arrangement Equity Instruments Other Than Options Outstanding
Unvested restricted stock as of December 31, 2020
Cybersecurity Risk Management Positions or Committees Responsible [Flag]
Finite-Lived Intangible Asset, Expected Amortization, Year Three
2028
Income tax benefit (expense)
Income Tax Expense (Benefit)
Income Tax Expense (Benefit), Total
Income Tax Expense
Income tax benefit (expense)
Income tax benefit (expense)
Debt Securities, Available-for-Sale, Unrealized Loss
Debt Securities, Available-for-Sale, Unrealized Loss
Debt Securities, Available-for-Sale, Unrealized Loss
Measurement Frequency [Axis]
Measurement Frequency
Temporary Equity, Shares Subscribed but Unissued
Temporary Equity, Shares Subscribed but Unissued
Amendment Description
Amendment Description
Payments to Acquire Productive Assets
Payments to Acquire Productive Assets, Total
Payment of PRV related obligations
Number of Common Stock Shares Purchased
Common Stock Shares Purchased
Common Stock Shares Purchased
Proceeds from Issuance of Common Stock
Proceeds from issuance of common stock, net
Proceeds from issuance of common stock, net
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Subsidiary, Ownership Percentage, Noncontrolling Owner
Ownership percentage
Entity Common Stock, Shares Outstanding
Entity Common Stock, Shares Outstanding
Entity Common Stock, Shares Outstanding
Concentration Risk, Credit Risk, Policy [Policy Text Block]
Concentration of Credit Risk and Other Risks and Uncertainties
Lessee, Operating Lease, Remaining Lease Term
Lessee operating lease renewal lease term
Liability Class [Axis]
Deferred Revenue, Revenue Recognized
Revenue Recorgnise
Accumulated Other Comprehensive Income (Loss), Net of Tax, Total
Accumulated Other Comprehensive Income (Loss), Net of Tax
Accumulated other comprehensive income
Performance Stock Options Member
Performance Stock Options [Member]
Performance Stock Options
Granted
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Grants in Period
Granted
Temporary Equity, by Class of Stock [Table]
Temporary Equity By Class Of Stock [Table]
Assets
Assets
Total assets
Inventory, Policy [Policy Text Block]
Inventory
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Weighted Average Remaining Contractual Term
Weighted-Average Remaining Contractual Term, Exercisable at December 31, 2025
Income Statement [Abstract]
Fair Value of Financial Instruments
Fair Value of Financial Instruments, Policy [Policy Text Block]
Unrecognized Tax Benefits, Decrease Resulting from Prior Period Tax Positions
Reductions based on tax positions related to prior year
Reductions based on tax positions related to prior year
Upfront license fee
Upfront License Fee
Upfront License Fee
Share-Based Payment Arrangement [Policy Text Block]
Share-Based Compensation
Deferred Income Tax Expense (Benefit)
Total deferred
Total deferred
Lessee operating lease incremental borrowing rate.
Lessee Operating Lease Incremental Borrowing Rate
Lessee operating lease incremental borrowing rate
Common stock issued in IPO, net of issuance costs of $16,995, shares
Stock Issued During Period, Shares, New Issues
Stock Issued During Period, Shares, New Issues
Shares Authorized
Temporary Equity, Shares Authorized
Temporary Equity, Shares Authorized
Vested
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Vested in Period
Vested
PRV-Related Obligation Payment [Member]
PRV-Related Obligation Payment [Member]
PRV-Related Obligation Payment [Member]
Earnings Per Share, Diluted
Net loss per share, basic and diluted
Net loss per share, diluted
Net (loss) income per share - diluted
Schedule of Segment Reporting Information, by Segment [Table Text Block]
Schedule of Segment Information
Available For Sale Securities Continuous Unrealized Loss Position More Than 12 Months Accumulated Loss
Available For Sale Securities Continuous Unrealized Loss Position More Than 12 Months Accumulated Loss
Unrealized losses 12 months or greater unrealized losses
Finite-Lived Intangible Asset, Expected Amortization, Year Five
2030
Purchase Commitment, Excluding Long-Term Commitment [Domain]
City Area Code
City Area Code
City Area Code
Auditor Name
Intangible Assets, Finite-Lived, Policy [Policy Text Block]
Intangible Assets, Net
Share-Based compensation [Member]
Share-Based compensation [Member]
Share-Based compensation [Member]
Other Intangible Assets [Member]
Other Intangible Assets [Member]
Deferred Tax Assets, Tax Credit Carryforwards, Total
Deferred Tax Assets, Tax Credit Carryforwards
Credits
Research and development tax credit, Amount
Research and development tax credit, Amount
Effective Income Tax Rate Reconciliation, Tax Credit, Research, Amount
Milestone Payments Received
Milestone Payments Received
Future milestone payments received
Temporary Equity Issue Price Per Share
Temporary Equity, Redemption Price Per Share
Tax Credit Carryforward, Expiration Year.
Tax Credit Carryforward Expiration Year
Tax Credit Carryforward, Expiration Year
Other [Member]
Other Member
Other
Incremental Stock Compensation Expense, Stock option Awards Granted To Employees.
Incremental Stock Compensation Expense, Stock option Awards Granted To Employees.
Incremental stock compensation expense, stock option awards granted to employees
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Aggregate Intrinsic Value, Vested
Exercised
Operating Lease, Weighted Average Remaining Lease Term
Weighted-average remaining lease term
Segment Reporting Information [Line Items]
Premium to volume weighted average price
Premium To Volume Weighted Average Price
Premium To Volume Weighted Average Price
Orphan drug credit, Percentage
Effective Income Tax Rate Reconciliation, Tax Credit, Other, Percent
Orphan drug credit, Percentage
Derivative liability at fair value
Derivative Liability, Fair Value, Gross Liability, Total
Derivative Liability, Subject to Master Netting Arrangement, before Offset
Cash and Cash Equivalents, Policy [Policy Text Block]
Cash and Cash Equivalents
Property and equipment, Gross
Property, Plant and Equipment, Net, Ending Balance
Property, Plant and Equipment, Net, Beginning Balance
Property, Plant and Equipment, Net
Property and equipment, net
Property and equipment, net
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Exercisable, Number
Exercisable at December 31, 2025
Loss from operations
Loss from operations
Operating Income (Loss)
Operating Income (Loss)
Two Thousand Twenty Four Private Placement [Member]
Two Thousand Twenty Four Private Placement [Member]
2024 Private Placement [Member]
Derivative Tranches Liability
Derivatives, Offsetting Fair Value Amounts, Policy [Policy Text Block]
Transaction Price
Transaction Price
Transaction Price
Payments of stock issuance costs
Payments of Stock Issuance Costs
Payments of Stock Issuance Costs
Eligible Participants
Defined Contribution Plan Number Of Eligible Participants
Defined Contribution Plan Number Of Eligible Participants
Operating Lease, Weighted Average Discount Rate, Percent
Weighted-average discount rate
Operating Lease, Liability, Noncurrent
Long-term portion of operating lease liabilities
Long-term portion of operating lease liabilities
Fair Value, Inputs, Level 1 [Member]
Fair Value, Inputs, Level 1
Class of Stock [Line Items]
Class Of Stock [Line Items]
Disclosure Text Block [Abstract]
Effective Income Tax Rate Reconciliation, Nondeductible Expense, Percent [Abstract]
Nontaxable or nondeductible items
Auditor Location
Deferred Tax Assets, Federal and state net operating loss carryforwards.
Deferred Tax Assets Federal And State Net Operating Loss Carryforwards
Federal and state net operating loss carryforwards
Nonoperating Income (Expense) [Abstract]
Non-operating income:
Derivative Contract [Domain]
Derivative Contract
US Government Corporations and Agencies Securities [Member]
U.S. government agency securities [Member]
Research and Experimental Expenses Amortization Period
Research and Experimental Expenses Amortization Period
Research and experimental expenses amortization period
Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table Text Block]
Summary of Outstanding Potentially Dilutive Securities Have Been Excluded From Calculation of Diluted Net Loss Per Share
Income Tax Jurisdiction [Domain]
Income Tax Authority
Entity Interactive Data Current
Entity Interactive Data Current
Entity Interactive Data Current
Statement of Income Location, Balance [Domain]
Income Statement Location
Defined Contribution Plan Employer Matching Contribution
Defined Contribution Plan Employer Matching Contribution
Matching Contribution
MabCare License Agreement [Member]
MabCare License Agreement [Member]
MabCare License Agreement [Member]
Payment of accrued interest.
Payment Of Accrued Interest
Payment Of Accrued Interest
Option Indexed to Issuer's Equity, Type [Domain]
Entity Tax Identification Number
Entity Tax Identification Number
Entity Tax Identification Number
Summary of Performance Stock Units activity
Summary of Performance Stock Units activity
Summary of Performance Stock Units activity
Share Price
Common share fair value
Purchase Price of Common Stock Per Share
Payment to Obligation of License Agreement
Payment to Obligation of License Agreement
Payment to obligation of license agreement
Agreement Axis
Agreement [Axis]
Agreement
Description of Business, Organization and Liquidity
Organization, Consolidation and Presentation of Financial Statements Disclosure [Text Block]
Description of Business and Organization
Two thousand and twenty one equity incentive plan.
Two Thousand And Twenty One Equity Incentive Plan
2021 Equity Incentive Plan [Member]
2021 Equity Incentive Plan [Member]
Schedule of Stock Options Roll Forward [Table Text Block]
Schedule Of Stock Options
Conditions For Issue Axis
Conditions For Issue [Axis]
Conditions For Issue
Local Phone Number
Local Phone Number
Local Phone Number
Related Party Transaction [Domain]
Debt Securities, Available-for-Sale, Unrealized Gain
Debt Securities, Available-for-Sale, Unrealized Gain
Auditor Opinion [Text Block]
Auditor Opinion
Changes in unrecognized tax benefits
Income Tax Reconciliation Nondeductible Expense Changes in Unrecognized tax Benefits
Income Tax Reconciliation Nondeductible Expense Changes in Unrecognized tax Benefits
Accounting Policies [Abstract]
Federal tax credits
Federal Tax Credits
Federal tax credits
Janssen License Agreement [Member]
Janssen License Agreement [Member]
Janssen License Agreement [Member]
Lessee, Operating Lease, Liability, to be Paid, Year Four
2029
Class of Stock [Domain]
Class of Stock
Class of Stock [Domain]
Accrued Professional Fees, Current
Accrued professional service expenses
Accrued professional service expenses
Milestone Payment Capitalized, Amount
Milestone Payment Capitalized, Amount
Milestone Payment Capitalized, Amount
Employee Stock Purchase Plan [Member]
Employee Stock Purchase Plan [Member]
Employee Stock Purchase Plan [Member]
Schedule of Accounts Payable and Accrued Liabilities [Table Text Block]
Schedule of Accrued Expenses and Other Current Liabilities
Schedule of Accrued expenses and other current liabilities
Stock, Class of Stock [Table]
Schedule Of Stock By Class [Table]
Entity Emerging Growth Company
Entity Emerging Growth Company
Entity Emerging Growth Company
Weighted-average vesting contractual term of the award
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Outstanding, Weighted Average Remaining Contractual Term
Vested and expected to vest at December 31, 2025
Indefinite-Lived Intangible Assets [Axis]
Area of Land
Area of land