v3.26.1
Pay vs Performance Disclosure - USD ($)
12 Months Ended
Dec. 31, 2025
Dec. 31, 2024
Dec. 31, 2023
Dec. 31, 2022
Dec. 31, 2021
Pay vs Performance Disclosure          
Pay vs Performance Disclosure, Table
Pay Versus Performance Disclosure
In accordance with rules adopted by the SEC pursuant to the Dodd-Frank Wall Street Reform and Consumer Protection Act of 2010, we provide the following disclosure regarding executive “Compensation Actually Paid” (“CAP”) and certain performance measures for the fiscal years listed below. The Compensation Discussion & Analysis (“CD&A”) describes the compensation setting process for our executive officers, which is done independently from the disclosure requirements.
Pay Versus Performance
The following table provides the information required for our NEOs for each of the fiscal years ended December 31, 2025, December 31, 2024, December 31, 2023, December 31, 2022, and December 31, 2021 along with the required financial information required for each fiscal year. CAP is calculated in accordance with SEC rules and includes the increase or decrease in value of certain elements of compensation over each fiscal year, including compensation granted in a prior year. CAP does not correlate to the total amount of cash or equity compensation paid or received during each fiscal year. The calculations do not reflect the actual sale of stock underlying equity awards or the exercise of stock options by the executive, and the amount of compensation ultimately received may, in fact, be different from the CAP amounts disclosed in the table below:
 
 
 
   
 
   
 
   
 
   
 
 
Value of Initial Fixed $100
Investment Based On:
   
 
   
 
Year
 
Summary
Compensation
Table Total
for PEO
 
Compensation
Actually Paid
to PEO
 
Average
Summary
Compensation
Table Total
for Non-PEO

NEOs
 
Average
Compensation
Actually Paid
to
Non-PEO

NEOs
 
Total
Shareholder
Return
 
Peer Group
Total
Shareholder
Return
 
Net
Income
(Loss)
(in
millions)
 
Revenue
(in
millions)
 
$
 
$
 
$
 
$
 
$
 
$
 
$
 
$
2025
      10,915,533       26,167,148       2,410,842       5,117,411       611.31       99.39       190.3       605.5
2024
      8,199,136       9,626,783       2,983,724       2,398,149       313.32       81.07       35.5       441.5
2023
      6,758,070       12,840,624       2,493,824       3,227,815       396.63       81.77       (25.0 )       241.6
2022
      3,287,862       25,221,304       958,883       4,539,307       310.15       76.75       (36.2 )       93.5
2021
      7,370,365       5,172,951       1,441,564       1,070,396       96.28       96.45       (44.2 )       30.3
 
(1)
For all years reported, the principal executive officer (“PEO”) was Waleed H. Hassanein, M.D.
 
(2)
Non-PEO
NEOs reflect the following executives for each covered fiscal year:
2025: Gerardo Hernandez, Tamer Khayal, M.D., Nicholas Corcoran, Anil Ranganath;
2024: Gerardo Hernandez, Tamer Khayal, M.D., Nicholas Corcoran, Anil Ranganath, Stephen Gordon;
2023: Stephen Gordon, Tamer Khayal, M.D., Nicholas Corcoran, Anil Ranganath;
2022: Stephen Gordon, Tamer Khayal, M.D., Miriam Provost, Laura Damme; and
2021: Stephen Gordon, Tamer Khayal, M.D., Miriam Provost, Laura Damme.
 
(3)
Deductions from, and additions to, total compensation in the Summary Compensation Table by year to calculate CAP are shown in the tables below.
 
 
 
  
2025
   
2024
   
2023
   
2022
   
2021
 
  
 
  
$
   
$
   
$
   
$
   
$
 
Summary Compensation Table Total
  
 
10,915,533
 
 
 
8,199,136
 
 
 
6,758,070
 
 
 
3,287,862
 
 
 
7,370,365
 
Adjustments for Stock and Option Awards
  
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Adjustment for grant date fair values in the Summary Compensation Table
     (8,724,160     (6,096,424     (4,940,574     (1,825,900     (6,377,940
Year-end
fair value of unvested awards granted in the covered fiscal year
     13,606,442       3,958,387       5,365,601       10,641,357       2,075,714  
Year-over-year difference of
year-end
fair values for unvested awards granted in prior years that remained outstanding at the covered fiscal year end
     4,892,258       (2,382,164     3,440,246       8,789,181       (136,012
Fair values at vest date for awards granted and vested in covered fiscal year
     1,546,395       971,689       532,735       1,647,831       949,688  
Difference in fair values between prior
year-end
fair values and vest date fair values for awards granted in prior years and vesting in the covered fiscal year
     3,941,653       4,976,159       1,684,546       2,680,973       1,291,136  
Compensation Actually Paid (as calculated)
  
 
26,167,148
 
 
 
9,626,783
 
 
 
12,840,624
 
 
 
25,221,304
 
 
 
5,172,951
 
 
 
 
  
Average CAP to
Non-PEO
NEOs
 
 
 
  
2025
   
2024
   
2023
   
2022
   
2021
 
  
 
  
$
   
$
   
$
   
$
   
$
 
Summary Compensation Table Total
  
 
2,410,842
 
 
 
2,983,724
 
 
 
2,493,824
 
 
 
958,883
 
 
 
1,441,564
 
Adjustments for Stock and Option Awards
  
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Adjustment for grant date fair values in the Summary Compensation Table
     (1,519,574     (2,053,545     (1,738,234     (328,662     (977,265
Year-end
fair value of unvested awards granted in the covered fiscal year
     2,228,435       1,079,261       1,822,445       1,915,468       318,056  
Year-over-year difference of
year-end
fair values for unvested awards granted in prior years that remained outstanding at the covered fiscal year end
     1,201,674       (371,623     372,583       1,344,252       (16,871
Fair values at vest date for awards granted and vested in covered fiscal year
     250,719       188,739       93,271       296,601       145,504  
Difference in fair values between prior
year-end
fair values and vest date fair values for awards granted in prior years and vesting in the covered fiscal year
     545,315       571,594       183,926       352,765       159,408  
Compensation Actually Paid (as calculated)
  
 
5,117,411
 
 
 
2,398,149
 
 
 
3,227,815
 
 
 
4,539,307
 
 
 
1,070,396
 
 
 
(4)
The valuation of RSU awards included as part of CAP was based on the grant date closing price and the closing price on the applicable vesting date or fiscal year end. The following summarizes the valuation assumptions used for stock option awards included as part of CAP:
 
  a.
Expected life of each stock option is based on the “simplified method” using an average of the remaining vesting period and remaining term, as of the applicable vesting date or fiscal year end.
  b.
The exercise price is based on each grant date closing price and fair value is based on the closing price on the applicable vesting date or fiscal year end.
  c.
Risk free rate is based on the Treasury Constant Maturity rate closest to the remaining expected life as of the applicable vesting date or fiscal year end.
  d.
Historical volatility is based on the daily price history for each year of remaining expected life prior to each applicable vesting date or fiscal year end; closing prices are provided by S&P Capital IQ and are adjusted for dividends and splits.
  e.
Annual dividend yield on each applicable vesting date or fiscal year end is assumed to be zero.
 
(5)
The following table illustrates the valuation assumptions as of the vesting date for stock options that vested in each of the covered fiscal years:
 
         
  
 
  
2025
  
2024
  
2023
  
2022
  
2021
Expected volatility
  
67.69% - 76.88%
  
72.02% - 77.95%
  
71.79% - 77.78%
  
69.15% - 76.30%
  
64.38% - 72.22%
Expected dividend yield
   0.00%    0.00%    0.00%    0.00%    0.00%
Expected term, in years
   3.0 - 5.0    3.0 - 5.0    3.0 - 5.0    3.2 - 5.0    3.0 - 5.0
Risk-free interest rate
   3.44% - 4.45%    3.44% - 4.81%    3.54% - 4.91%    0.97% - 4.48%    0.19% - 1.34%
 
(6)
The amounts reported in this column represent the cumulative total return on $100 invested in the Company’s common stock as of December 31, 2020 through the last trading day for the applicable fiscal year in the table. The Company has not paid any dividends since its IPO.
 
(7)
The amounts reported in this column represent the weighted cumulative total return on $100 invested as of December 31, 2020 through the last trading day for the applicable fiscal year in the table, weighted according to the respective companies’ stock market capitalization at the beginning of each period for which a return is indicated. The peer group total shareholder return set forth in this table utilizes the Nasdaq Healthcare Index (IXHC), which we also utilize in the stock performance graph required by Item 201(e) of Regulation
S-K
included in our Annual Report on Form
10-K
for the year ended December 31, 2025. The return of this index is calculated assuming reinvestment of dividends during the period presented.
 
(8)
The amounts reported in this column represent the amount of net income (loss) reflected in the Company’s audited financial statements for the applicable year.
 
(9)
The amounts reported in this column represent revenue, our Company-Selected Measure, which we believe is the most important financial measure used to link compensation actually paid to our named executive officers to Company performance for 2025. The amounts represent the amount of revenue reflected in the Company’s audited financial statements for the applicable year.
       
Company Selected Measure Name Revenue        
Named Executive Officers, Footnote
(2)
Non-PEO
NEOs reflect the following executives for each covered fiscal year:
2025: Gerardo Hernandez, Tamer Khayal, M.D., Nicholas Corcoran, Anil Ranganath;
2024: Gerardo Hernandez, Tamer Khayal, M.D., Nicholas Corcoran, Anil Ranganath, Stephen Gordon;
2023: Stephen Gordon, Tamer Khayal, M.D., Nicholas Corcoran, Anil Ranganath;
2022: Stephen Gordon, Tamer Khayal, M.D., Miriam Provost, Laura Damme; and
2021: Stephen Gordon, Tamer Khayal, M.D., Miriam Provost, Laura Damme.
 
       
Peer Group Issuers, Footnote The peer group total shareholder return set forth in this table utilizes the Nasdaq Healthcare Index (IXHC), which we also utilize in the stock performance graph required by Item 201(e) of Regulation
S-K
included in our Annual Report on Form
10-K
for the year ended December 31, 2025. The return of this index is calculated assuming reinvestment of dividends during the period presented.
       
PEO Total Compensation Amount $ 10,915,533 $ 8,199,136 $ 6,758,070 $ 3,287,862 $ 7,370,365
PEO Actually Paid Compensation Amount $ 26,167,148 9,626,783 12,840,624 25,221,304 5,172,951
Adjustment To PEO Compensation, Footnote
(3)
Deductions from, and additions to, total compensation in the Summary Compensation Table by year to calculate CAP are shown in the tables below.
 
 
 
  
2025
   
2024
   
2023
   
2022
   
2021
 
  
 
  
$
   
$
   
$
   
$
   
$
 
Summary Compensation Table Total
  
 
10,915,533
 
 
 
8,199,136
 
 
 
6,758,070
 
 
 
3,287,862
 
 
 
7,370,365
 
Adjustments for Stock and Option Awards
  
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Adjustment for grant date fair values in the Summary Compensation Table
     (8,724,160     (6,096,424     (4,940,574     (1,825,900     (6,377,940
Year-end
fair value of unvested awards granted in the covered fiscal year
     13,606,442       3,958,387       5,365,601       10,641,357       2,075,714  
Year-over-year difference of
year-end
fair values for unvested awards granted in prior years that remained outstanding at the covered fiscal year end
     4,892,258       (2,382,164     3,440,246       8,789,181       (136,012
Fair values at vest date for awards granted and vested in covered fiscal year
     1,546,395       971,689       532,735       1,647,831       949,688  
Difference in fair values between prior
year-end
fair values and vest date fair values for awards granted in prior years and vesting in the covered fiscal year
     3,941,653       4,976,159       1,684,546       2,680,973       1,291,136  
Compensation Actually Paid (as calculated)
  
 
26,167,148
 
 
 
9,626,783
 
 
 
12,840,624
 
 
 
25,221,304
 
 
 
5,172,951
 
       
Non-PEO NEO Average Total Compensation Amount $ 2,410,842 2,983,724 2,493,824 958,883 1,441,564
Non-PEO NEO Average Compensation Actually Paid Amount $ 5,117,411 2,398,149 3,227,815 4,539,307 1,070,396
Adjustment to Non-PEO NEO Compensation Footnote
(3)
Deductions from, and additions to, total compensation in the Summary Compensation Table by year to calculate CAP are shown in the tables below.
 
 
 
  
Average CAP to
Non-PEO
NEOs
 
 
 
  
2025
   
2024
   
2023
   
2022
   
2021
 
  
 
  
$
   
$
   
$
   
$
   
$
 
Summary Compensation Table Total
  
 
2,410,842
 
 
 
2,983,724
 
 
 
2,493,824
 
 
 
958,883
 
 
 
1,441,564
 
Adjustments for Stock and Option Awards
  
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Adjustment for grant date fair values in the Summary Compensation Table
     (1,519,574     (2,053,545     (1,738,234     (328,662     (977,265
Year-end
fair value of unvested awards granted in the covered fiscal year
     2,228,435       1,079,261       1,822,445       1,915,468       318,056  
Year-over-year difference of
year-end
fair values for unvested awards granted in prior years that remained outstanding at the covered fiscal year end
     1,201,674       (371,623     372,583       1,344,252       (16,871
Fair values at vest date for awards granted and vested in covered fiscal year
     250,719       188,739       93,271       296,601       145,504  
Difference in fair values between prior
year-end
fair values and vest date fair values for awards granted in prior years and vesting in the covered fiscal year
     545,315       571,594       183,926       352,765       159,408  
Compensation Actually Paid (as calculated)
  
 
5,117,411
 
 
 
2,398,149
 
 
 
3,227,815
 
 
 
4,539,307
 
 
 
1,070,396
 
       
Compensation Actually Paid vs. Total Shareholder Return

       
Compensation Actually Paid vs. Net Income

       
Compensation Actually Paid vs. Company Selected Measure

       
Total Shareholder Return Vs Peer Group

       
Tabular List, Table
Tabular List of Financial Performance Measures
As described in greater detail in the CD&A, we have a significant focus on
pay-for-performance.
The most important financial and
non-financial
performance measures used to link CAP (as calculated in accordance with the SEC rules) to our NEOs in 2025 to our performance were:
 
 
Revenue target of $545M;
 
 
Initiation of a US Lung clinical program and enrolling approximately 150 OCS cases by December 31, 2025;
 
 
Initiation of a US Heart clinical program and enrolling approximately 150 heart cases by December 31, 2025;
 
 
Initiation of OCS Liver NOP programs in six new US liver centers by December 31, 2025;
 
 
Maintain positive EBITDA for all four quarters of 2025;
 
 
Launch of NOP Connect to manage all NOP services by June 30, 2025;
 
 
Establish OCS NOP program in two countries outside the United States by December 31, 2025;
 
 
Complete MES and Workday headcount planning modules by September 30, 2025 and develop business digital transformation roadmap by December 31, 2025;
 
 
 
 
Complete the architectural design of the fully-automated and remote-controlled OCS NextGen Tech platform and initiate key third-party developers by December 31, 2025; and
 
 
Complete the architectural design of OCS Kidney by December 31, 2025.
       
Total Shareholder Return Amount $ 611.31 313.32 396.63 310.15 96.28
Peer Group Total Shareholder Return Amount 99.39 81.07 81.77 76.75 96.45
Net Income (Loss) $ 190,300,000 $ 35,500,000 $ (25,000,000) $ (36,200,000) $ (44,200,000)
Company Selected Measure Amount 605,500,000 441,500,000 241,600,000 93,500,000 30,300,000
PEO Name Waleed H. Hassanein, M.D. Waleed H. Hassanein, M.D. Waleed H. Hassanein, M.D. Waleed H. Hassanein, M.D. Waleed H. Hassanein, M.D.
Measure:: 1          
Pay vs Performance Disclosure          
Name Revenue target of $545M        
Measure:: 2          
Pay vs Performance Disclosure          
Name Initiation of a US Lung clinical program and enrolling approximately 150 OCS cases by December 31, 2025        
Measure:: 3          
Pay vs Performance Disclosure          
Name Initiation of a US Heart clinical program and enrolling approximately 150 heart cases by December 31, 2025        
Measure:: 4          
Pay vs Performance Disclosure          
Name Initiation of OCS Liver NOP programs in six new US liver centers by December 31, 2025        
Measure:: 5          
Pay vs Performance Disclosure          
Name Maintain positive EBITDA for all four quarters of 2025        
Measure:: 6          
Pay vs Performance Disclosure          
Name Launch of NOP Connect to manage all NOP services by June 30, 2025        
Measure:: 7          
Pay vs Performance Disclosure          
Name Establish OCS NOP program in two countries outside the United States by December 31, 2025        
Measure:: 8          
Pay vs Performance Disclosure          
Name Complete MES and Workday headcount planning modules by September 30, 2025 and develop business digital transformation roadmap by December 31, 2025        
Measure:: 9          
Pay vs Performance Disclosure          
Name Complete the architectural design of the fully-automated and remote-controlled OCS NextGen Tech platform and initiate key third-party developers by December 31, 2025        
Measure:: 10          
Pay vs Performance Disclosure          
Name Complete the architectural design of OCS Kidney by December 31, 2025.        
PEO | Aggregate Grant Date Fair Value of Equity Award Amounts Reported in Summary Compensation Table          
Pay vs Performance Disclosure          
Adjustment to Compensation, Amount $ (8,724,160) $ (6,096,424) $ (4,940,574) $ (1,825,900) $ (6,377,940)
PEO | Year-end Fair Value of Equity Awards Granted in Covered Year that are Outstanding and Unvested          
Pay vs Performance Disclosure          
Adjustment to Compensation, Amount 13,606,442 3,958,387 5,365,601 10,641,357 2,075,714
PEO | Year-over-Year Change in Fair Value of Equity Awards Granted in Prior Years That are Outstanding and Unvested          
Pay vs Performance Disclosure          
Adjustment to Compensation, Amount 4,892,258 (2,382,164) 3,440,246 8,789,181 (136,012)
PEO | Vesting Date Fair Value of Equity Awards Granted and Vested in Covered Year          
Pay vs Performance Disclosure          
Adjustment to Compensation, Amount 1,546,395 971,689 532,735 1,647,831 949,688
PEO | Change in Fair Value as of Vesting Date of Prior Year Equity Awards Vested in Covered Year          
Pay vs Performance Disclosure          
Adjustment to Compensation, Amount 3,941,653 4,976,159 1,684,546 2,680,973 1,291,136
Non-PEO NEO | Aggregate Grant Date Fair Value of Equity Award Amounts Reported in Summary Compensation Table          
Pay vs Performance Disclosure          
Adjustment to Compensation, Amount (1,519,574) (2,053,545) (1,738,234) (328,662) (977,265)
Non-PEO NEO | Year-end Fair Value of Equity Awards Granted in Covered Year that are Outstanding and Unvested          
Pay vs Performance Disclosure          
Adjustment to Compensation, Amount 2,228,435 1,079,261 1,822,445 1,915,468 318,056
Non-PEO NEO | Year-over-Year Change in Fair Value of Equity Awards Granted in Prior Years That are Outstanding and Unvested          
Pay vs Performance Disclosure          
Adjustment to Compensation, Amount 1,201,674 (371,623) 372,583 1,344,252 (16,871)
Non-PEO NEO | Vesting Date Fair Value of Equity Awards Granted and Vested in Covered Year          
Pay vs Performance Disclosure          
Adjustment to Compensation, Amount 250,719 188,739 93,271 296,601 145,504
Non-PEO NEO | Change in Fair Value as of Vesting Date of Prior Year Equity Awards Vested in Covered Year          
Pay vs Performance Disclosure          
Adjustment to Compensation, Amount $ 545,315 $ 571,594 $ 183,926 $ 352,765 $ 159,408