<?xml version="1.0" encoding="utf-8"?>
<!--XBRL document created by Certent Disclosure Management 25.4.0.1 -->
<!--Based on XBRL 2.1-->
<!--Created on: 4/6/2026 6:55:31 AM-->
<!--Modified on: 4/6/2026 6:55:31 AM-->
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  <xsd:annotation>
    <xsd:appinfo><link:roleType roleURI="http://www.chemed.com/role/DocumentDocumentAndEntityInformation" id="DocumentDocumentAndEntityInformation"><link:definition>000090 - Document - Document And Entity Information</link:definition><link:usedOn>link:presentationLink</link:usedOn><link:usedOn>link:calculationLink</link:usedOn><link:usedOn>link:definitionLink</link:usedOn></link:roleType><link:linkbaseRef xlink:arcrole="http://www.w3.org/1999/xlink/properties/linkbase" xlink:href="che-20251231_def.xml" xlink:role="http://www.xbrl.org/2003/role/definitionLinkbaseRef" xlink:type="simple"></link:linkbaseRef><link:linkbaseRef xlink:arcrole="http://www.w3.org/1999/xlink/properties/linkbase" xlink:href="che-20251231_lab.xml" xlink:role="http://www.xbrl.org/2003/role/labelLinkbaseRef" xlink:type="simple"></link:linkbaseRef><link:linkbaseRef xlink:arcrole="http://www.w3.org/1999/xlink/properties/linkbase" xlink:href="che-20251231_pre.xml" xlink:role="http://www.xbrl.org/2003/role/presentationLinkbaseRef" xlink:type="simple"></link:linkbaseRef></xsd:appinfo></xsd:annotation>
  <xsd:import namespace="http://www.xbrl.org/2003/instance" schemaLocation="http://www.xbrl.org/2003/xbrl-instance-2003-12-31.xsd"></xsd:import>
  <xsd:import namespace="http://www.xbrl.org/2003/linkbase" schemaLocation="http://www.xbrl.org/2003/xbrl-linkbase-2003-12-31.xsd"></xsd:import>
  <xsd:import namespace="http://xbrl.org/2005/xbrldt" schemaLocation="http://www.xbrl.org/2005/xbrldt-2005.xsd"></xsd:import>
  <xsd:import namespace="http://xbrl.sec.gov/dei/2025" schemaLocation="https://xbrl.sec.gov/dei/2025/dei-2025.xsd"></xsd:import>
  <xsd:import namespace="http://www.xbrl.org/dtr/type/2024-01-31" schemaLocation="https://www.xbrl.org/dtr/type/2024-01-31/types.xsd" xmlns="http://www.w3.org/2001/XMLSchema"></xsd:import>
  <xsd:import namespace="http://fasb.org/us-gaap/2025" schemaLocation="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd" xmlns="http://www.w3.org/2001/XMLSchema"></xsd:import>
  <xsd:import namespace="http://xbrl.sec.gov/ecd/2025" schemaLocation="https://xbrl.sec.gov/ecd/2025/ecd-2025.xsd" xmlns="http://www.w3.org/2001/XMLSchema"></xsd:import>
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  <xsd:element id="che_ValuesReportedInStockOptionsColumnOnSummaryCompensationTableMember" name="ValuesReportedInStockOptionsColumnOnSummaryCompensationTableMember" nillable="true" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" xmlns="http://www.w3.org/2001/XMLSchema"></xsd:element>
  <xsd:element id="che_YearEndFairValueForStockAwardsGrantedInCoveredFiscalYearOutstandingAndUnvestedMember" name="YearEndFairValueForStockAwardsGrantedInCoveredFiscalYearOutstandingAndUnvestedMember" nillable="true" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" xmlns="http://www.w3.org/2001/XMLSchema"></xsd:element>
  <xsd:element id="che_YearEndFairValueForStockOptionsGrantedInCoveredFiscalYearOutstandingAndUnvestedMember" name="YearEndFairValueForStockOptionsGrantedInCoveredFiscalYearOutstandingAndUnvestedMember" nillable="true" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" xmlns="http://www.w3.org/2001/XMLSchema"></xsd:element>
  <xsd:element id="che_PriorYearStockAwardsFairValueMember" name="PriorYearStockAwardsFairValueMember" nillable="true" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" xmlns="http://www.w3.org/2001/XMLSchema"></xsd:element>
  <xsd:element id="che_PriorYearStockOptionsFairValueMember" name="PriorYearStockOptionsFairValueMember" nillable="true" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" xmlns="http://www.w3.org/2001/XMLSchema"></xsd:element></schema>
