|
|
Shares
|
Value
|
|
|
Common Stocks & Other Equity Interests–96.78%
|
|||
|
Biotechnology–28.59%
|
|||
|
AbbVie, Inc.
|
277,017
|
$61,777,561
|
|
|
ADMA Biologics, Inc.(b)
|
136,705
|
2,364,996
|
|
|
Alnylam Pharmaceuticals, Inc.(b)
|
36,773
|
12,431,480
|
|
|
argenx SE, ADR (Netherlands)(b)
|
52,976
|
44,526,328
|
|
|
Arrowhead Pharmaceuticals, Inc.(b)
|
18,515
|
1,283,645
|
|
|
Ascendis Pharma A/S, ADR (Denmark)(b)
|
94,558
|
21,379,564
|
|
|
BeOne Medicines Ltd., ADR(b)
|
9,251
|
3,148,855
|
|
|
BridgeBio Pharma, Inc.(b)
|
216,227
|
16,707,860
|
|
|
Caris Life Sciences, Inc.(b)
|
110,484
|
2,558,809
|
|
|
Cogent Biosciences, Inc.(b)(c)
|
74,261
|
2,666,713
|
|
|
Cytokinetics, Inc.(b)(c)
|
48,114
|
3,040,324
|
|
|
Exelixis, Inc.(b)
|
96,756
|
4,001,828
|
|
|
Gilead Sciences, Inc.
|
337,004
|
47,837,718
|
|
|
Halozyme Therapeutics, Inc.(b)
|
155,098
|
11,122,078
|
|
|
Insmed, Inc.(b)
|
120,502
|
18,903,149
|
|
|
Ionis Pharmaceuticals, Inc.(b)(c)
|
107,312
|
8,871,483
|
|
|
Madrigal Pharmaceuticals, Inc.(b)(c)
|
21,162
|
10,354,778
|
|
|
Natera, Inc.(b)
|
86,013
|
19,881,045
|
|
|
Nuvalent, Inc., Class A(b)(c)
|
33,246
|
3,420,681
|
|
|
Protagonist Therapeutics, Inc.(b)
|
103,952
|
8,503,274
|
|
|
Regeneron Pharmaceuticals, Inc.
|
18,122
|
13,436,557
|
|
|
Revolution Medicines, Inc.(b)
|
27,141
|
2,631,320
|
|
|
Rhythm Pharmaceuticals, Inc.(b)
|
30,683
|
3,145,621
|
|
|
United Therapeutics Corp.(b)
|
26,773
|
12,569,656
|
|
|
Vertex Pharmaceuticals, Inc.(b)
|
32,280
|
15,168,372
|
|
|
|
|
|
351,733,695
|
|
Health Care Distributors–8.73%
|
|||
|
Cardinal Health, Inc.
|
44,523
|
9,567,102
|
|
|
Cencora, Inc.
|
162,214
|
58,270,513
|
|
|
McKesson Corp.
|
47,553
|
39,526,529
|
|
|
|
|
|
107,364,144
|
|
Health Care Equipment–13.83%
|
|||
|
Boston Scientific Corp.(b)
|
670,569
|
62,718,318
|
|
|
Edwards Lifesciences Corp.(b)
|
140,197
|
11,406,428
|
|
|
Globus Medical, Inc., Class A(b)
|
65,282
|
5,919,772
|
|
|
IDEXX Laboratories, Inc.(b)
|
29,150
|
19,543,909
|
|
|
Insulet Corp.(b)
|
52,804
|
13,507,791
|
|
|
Intuitive Surgical, Inc.(b)
|
45,537
|
22,960,666
|
|
|
IRhythm Holdings, Inc.(b)
|
47,015
|
7,264,288
|
|
|
LeMaitre Vascular, Inc.(c)
|
44,039
|
3,741,994
|
|
|
STERIS PLC
|
29,417
|
7,724,904
|
|
|
Stryker Corp.
|
29,378
|
10,856,934
|
|
|
TransMedics Group, Inc.(b)(c)
|
33,601
|
4,501,694
|
|
|
|
|
|
170,146,698
|
|
Health Care Facilities–4.30%
|
|||
|
Encompass Health Corp.
|
143,359
|
13,551,726
|
|
|
HCA Healthcare, Inc.
|
49,432
|
24,136,163
|
|
|
Tenet Healthcare Corp.(b)
|
80,222
|
15,184,420
|
|
|
|
|
|
52,872,309
|
|
Health Care REITs–1.84%
|
|||
|
Welltower, Inc.
|
120,441
|
22,686,267
|
|
|
|
Shares
|
Value
|
|
|
Health Care Services–5.68%
|
|||
|
BillionToOne, Inc.(b)(c)
|
14,768
|
$1,218,508
|
|
|
BrightSpring Health Services, Inc.(b)(c)
|
482,157
|
18,934,305
|
|
|
CVS Health Corp.
|
119,228
|
8,884,871
|
|
|
GeneDx Holdings Corp.(b)(c)
|
50,738
|
4,884,040
|
|
|
Guardant Health, Inc.(b)
|
189,772
|
21,641,599
|
|
|
Labcorp Holdings, Inc.
|
22,180
|
6,022,314
|
|
|
Quest Diagnostics, Inc.
|
20,984
|
3,924,637
|
|
|
RadNet, Inc.(b)
|
62,732
|
4,397,513
|
|
|
|
|
|
69,907,787
|
|
Health Care Technology–0.30%
|
|||
|
Heartflow, Inc.(b)(c)
|
121,178
|
3,619,587
|
|
|
Life Sciences Tools & Services–7.04%
|
|||
|
Agilent Technologies, Inc.
|
87,517
|
11,714,150
|
|
|
BioLife Solutions, Inc.(b)
|
151,657
|
3,306,123
|
|
|
ICON PLC(b)
|
25,368
|
4,572,582
|
|
|
Lonza Group AG (Switzerland)
|
14,888
|
10,115,652
|
|
|
Medpace Holdings, Inc.(b)
|
12,424
|
7,236,731
|
|
|
Mettler-Toledo International, Inc.(b)
|
9,732
|
13,364,372
|
|
|
Repligen Corp.(b)
|
50,803
|
7,588,444
|
|
|
Thermo Fisher Scientific, Inc.
|
49,606
|
28,702,528
|
|
|
|
|
|
86,600,582
|
|
Managed Health Care–2.25%
|
|||
|
Alignment Healthcare, Inc.(b)
|
309,133
|
6,964,767
|
|
|
HealthEquity, Inc.(b)
|
43,670
|
3,741,209
|
|
|
UnitedHealth Group, Inc.
|
59,237
|
16,996,872
|
|
|
|
|
|
27,702,848
|
|
Pharmaceuticals–24.22%
|
|||
|
AstraZeneca PLC, ADR (United Kingdom)
|
504,742
|
46,824,915
|
|
|
Axsome Therapeutics, Inc.(b)
|
87,700
|
16,158,725
|
|
|
Eli Lilly and Co.
|
113,267
|
117,474,869
|
|
|
Galderma Group AG, Class A (Switzerland)
|
49,726
|
9,268,874
|
|
|
Johnson & Johnson
|
184,830
|
42,002,618
|
|
|
Ligand Pharmaceuticals, Inc.(b)(c)
|
40,048
|
7,693,221
|
|
|
Phathom Pharmaceuticals, Inc.(b)(c)
|
184,910
|
2,527,720
|
|
|
Rapport Therapeutics, Inc.(b)(c)
|
109,966
|
2,926,195
|
|
|
Royalty Pharma PLC, Class A
|
440,990
|
18,380,463
|
|
|
Sandoz Group AG (Switzerland)
|
150,537
|
11,926,418
|
|
|
Tarsus Pharmaceuticals, Inc.(b)
|
77,845
|
5,024,116
|
|
|
UCB S.A. (Belgium)
|
58,259
|
17,753,000
|
|
|
|
|
|
297,961,134
|
|
Total Common Stocks & Other Equity Interests
(Cost $737,952,842)
|
1,190,595,051
|
||
|
Money Market Funds–2.81%
|
|||
|
Invesco Government & Agency Portfolio,
Institutional Class, 3.61%(d)(e)
|
11,868,146
|
11,868,146
|
|
|
|
Shares
|
Value
|
|
|
Money Market Funds–(continued)
|
|||
|
Invesco Treasury Portfolio, Institutional
Class, 3.57%(d)(e)
|
22,695,004
|
$22,695,004
|
|
|
Total Money Market Funds (Cost $34,563,150)
|
34,563,150
|
||
|
TOTAL INVESTMENTS IN SECURITIES
(excluding investments purchased
with cash collateral from securities
on loan)-99.59%
(Cost $772,515,992)
|
|
|
1,225,158,201
|
|
Investments Purchased with Cash Collateral from
Securities on Loan
|
|||
|
Money Market Funds–3.47%
|
|||
|
Invesco Private Government Fund,
3.65%(d)(e)(f)
|
11,873,857
|
11,873,857
|
|
|
|
Shares
|
Value
|
|
|
Money Market Funds–(continued)
|
|||
|
Invesco Private Prime Fund, 3.80%(d)(e)(f)
|
30,847,581
|
$30,856,835
|
|
|
Total Investments Purchased with Cash Collateral
from Securities on Loan (Cost $42,730,692)
|
42,730,692
|
||
|
TOTAL INVESTMENTS IN SECURITIES–103.06%
(Cost $815,246,684)
|
1,267,888,893
|
||
|
OTHER ASSETS LESS LIABILITIES—(3.06)%
|
(37,660,470
)
|
||
|
NET ASSETS–100.00%
|
$1,230,228,423
|
||
|
ADR
|
– American Depositary Receipt
|
|
REIT
|
– Real Estate Investment Trust
|
|
(a)
|
Industry and/or sector classifications used in this report are generally according
to the Global Industry Classification Standard, which was developed by and is the
exclusive property and a service mark of MSCI Inc. and Standard & Poor’s.
|
|
(b)
|
Non-income producing security.
|
|
(c)
|
All or a portion of this security was out on loan at January 31, 2026.
|
|
(d)
|
Affiliated holding. Affiliated holdings are investments in entities which are under
common ownership or control of Invesco Ltd. or are investments in entities in
which the Fund owns 5% or more of the outstanding voting securities. The table below shows the Fund’s transactions in, and earnings from, its investments in
affiliates for the three months ended January 31, 2026.
|
|
|
Value
October 31, 2025
|
Purchases
at Cost
|
Proceeds
from Sales
|
Change in
Unrealized
Appreciation
|
Realized
Gain
(Loss)
|
Value
January 31, 2026
|
Dividend Income
|
|
Investments in Affiliated Money Market Funds:
|
|
|
|
|
|
|
|
|
Invesco Government & Agency Portfolio,
Institutional Class
|
$9,293,643
|
$37,540,135
|
$(34,965,632)
|
$-
|
$-
|
$11,868,146
|
$83,432
|
|
Invesco Treasury Portfolio, Institutional Class
|
17,913,782
|
69,717,395
|
(64,936,173)
|
-
|
-
|
22,695,004
|
159,306
|
|
Investments Purchased with Cash Collateral
from Securities on Loan:
|
|
|
|
|
|
|
|
|
Invesco Private Government Fund
|
9,367,806
|
59,473,911
|
(56,967,860)
|
-
|
-
|
11,873,857
|
81,407*
|
|
Invesco Private Prime Fund
|
24,364,368
|
86,941,625
|
(80,449,158)
|
190
|
(190)
|
30,856,835
|
210,951*
|
|
Total
|
$60,939,599
|
$253,673,066
|
$(237,318,823)
|
$190
|
$(190)
|
$77,293,842
|
$535,096
|
|
*
|
Represents the income earned on the investment of cash collateral. Does not include
rebates and fees paid to lending agent or premiums received from
borrowers, if any.
|
|
(e)
|
The rate shown is the 7-day SEC standardized yield as of January 31, 2026.
|
|
(f)
|
The security has been segregated to satisfy the commitment to return the cash collateral received in securities lending transactions upon the borrower’s return of
the securities loaned.
|
|
|
Level 1
|
Level 2
|
Level 3
|
Total
|
|
Investments in Securities
|
|
|
|
|
|
Common Stocks & Other Equity Interests
|
$1,141,531,107
|
$49,063,944
|
$—
|
$1,190,595,051
|
|
Money Market Funds
|
34,563,150
|
42,730,692
|
—
|
77,293,842
|
|
Total Investments
|
$1,176,094,257
|
$91,794,636
|
$—
|
$1,267,888,893
|