Significant transactions (Details) $ in Thousands |
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1 Months Ended |
12 Months Ended |
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Dec. 02, 2025
EUR (€)
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Oct. 31, 2025
EUR (€)
bond
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Jan. 29, 2024
USD ($)
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Dec. 22, 2023
EUR (€)
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Dec. 04, 2023
USD ($)
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Jul. 07, 2023
USD ($)
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Oct. 18, 2022
EUR (€)
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Jan. 01, 2021 |
Feb. 03, 2020
USD ($)
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Dec. 21, 2018
USD ($)
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Jun. 30, 2021
USD ($)
patient
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Mar. 31, 2019
EUR (€)
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Jan. 31, 2019 |
Oct. 31, 2018
EUR (€)
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Dec. 31, 2025
EUR (€)
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Dec. 31, 2025
USD ($)
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Dec. 31, 2024
EUR (€)
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Dec. 31, 2023
EUR (€)
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Dec. 31, 2023
USD ($)
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Dec. 31, 2022
USD ($)
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Dec. 31, 2021
USD ($)
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Dec. 31, 2025
USD ($)
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Oct. 31, 2025
USD ($)
bond
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Dec. 22, 2023
USD ($)
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Oct. 12, 2023
EUR (€)
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Jul. 19, 2023
USD ($)
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Jul. 07, 2023
EUR (€)
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Jul. 07, 2023
USD ($)
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Dec. 31, 2022
EUR (€)
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Dec. 31, 2022
USD ($)
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Jul. 31, 2018
EUR (€)
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| Disclosure of transactions between related parties [line items] |
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| Capital increases |
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€ 1,535,000
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€ 0
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€ 60,154,000
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| Milestone payment upon second regulatory approval | $ |
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$ 750
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| Proceeds from borrowings |
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42,933,000
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0
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0
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| Loans repayments |
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3,549,000
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3,075,000
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€ 2,971,000
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| Non-current financial liabilities |
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91,010,000
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45,978,000
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| Prepaid expenses |
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2,318,000
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3,195,000
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| JNJ-1900 (NBTXR3) |
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| Disclosure of transactions between related parties [line items] |
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| Initial fixed return amount capped |
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€ 124,000,000
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| Repayment of full funding received | $ |
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$ 2,500
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| Repayment of only partial funding received | $ |
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1,760
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| Debt issuance costs |
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€ 2,900,000
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3,200
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| JNJ-1900 (NBTXR3) | Period One |
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| Disclosure of transactions between related parties [line items] |
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| Annual royalty repayment threshold | $ |
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$ 1,000,000
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| Subscription price if repaid on or prior percent |
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175.00%
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175.00%
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| JNJ-1900 (NBTXR3) | Period Two |
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| Disclosure of transactions between related parties [line items] |
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| Annual royalty repayment threshold | $ |
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$ 750,000
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| Subscription price if repaid on or prior percent |
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250.00%
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250.00%
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| Collaboration agreement, maximum net sales | $ |
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$ 14,900
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| Repayment terms tail period expires period |
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10 years
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| Event One | Maximum |
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| Disclosure of transactions between related parties [line items] |
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| Milestone payment increase | $ |
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$ 2,200
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| Event Two | Maximum |
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| Disclosure of transactions between related parties [line items] |
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| Milestone payment increase | $ |
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16,400
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| EIB Loan |
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| Disclosure of transactions between related parties [line items] |
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| Proceeds from borrowings |
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€ 14,000,000
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€ 16,000,000
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| Borrowings, interest rate |
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5.00%
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6.00%
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21.30%
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21.30%
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21.30%
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21.30%
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| Undrawn borrowing facilities |
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€ 10,000,000
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| Royalties agreement, period |
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6 years
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6 years
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| Remaining notional amount |
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€ 25,300,000
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| Net sales threshold |
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5,000,000.0
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| Accrued interest |
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5,400,000
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€ 5,400,000
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| Milestone payment |
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€ 20,000,000
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€ 20,000,000.0
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| First installment period |
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1 year
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| Second installment period |
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2 years
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| Prorated payment, maximum percentage of milestone payment |
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10.00%
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| Borrowings, cumulative milestone prepayment amount |
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100,000,000
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| Loans repayments |
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900,000
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200,000
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€ 800,000
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| Non-current financial liabilities |
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18,100,000
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€ 19,000,000.0
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| EIB Loan | Milestone Two |
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| Disclosure of transactions between related parties [line items] |
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| Borrowings, interest rate |
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2.00%
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2.00%
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| Debt instrument, bond Issuance threshold | bond |
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50,000
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50,000
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| EIB Loan | Milestone Three |
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| Disclosure of transactions between related parties [line items] |
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| Borrowings, interest rate |
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2.00%
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2.00%
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| Proceeds from component of royalty financing |
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€ 2,500,000
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| Royalty Financing Agreement |
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| Disclosure of transactions between related parties [line items] |
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| Debt instrument, bond Issuance threshold | bond |
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50,000
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50,000
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| Maximum borrowing amount |
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€ 71,000,000
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| Aggregate nominal value |
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2,500,000
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| Proceeds from current borrowings |
€ 50,000,000
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| Description of expected future cash in flows | $ |
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$ 21,000
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| Premium on issuance of debt instruments | $ |
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$ 68,500
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| Annual royalty repayment, estimated initial payment |
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€ 42,900,000
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$ 50,000
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| First Tranche | EIB Loan |
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| Disclosure of transactions between related parties [line items] |
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| Borrowings, interest rate |
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6.00%
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| Remaining notional amount |
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€ 16,000,000
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| Second Tranche | EIB Loan |
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| Disclosure of transactions between related parties [line items] |
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| Borrowings, interest rate |
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5.00%
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Remaining notional amount |
|
|
|
|
|
|
€ 9,300,000
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Second Tranche | EIB fixed rate loan, tranche two |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Disclosure of transactions between related parties [line items] |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Remaining notional amount |
|
|
|
|
|
|
€ 9,300,000
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Top of Range | EIB Loan |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Disclosure of transactions between related parties [line items] |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Notional amount |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
€ 40,000,000
|
| Maximum | EIB Loan |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Disclosure of transactions between related parties [line items] |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Notional amount |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
€ 40,000,000
|
| Janssen |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Disclosure of transactions between related parties [line items] |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Collaboration agreement, upfront payment license fee | $ |
|
|
|
|
|
$ 30,000
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Collaboration agreement, success-based payment | $ |
|
|
|
|
|
1,800,000
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Proceeds from milestone payment | $ |
|
|
$ 20,000
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Capital increases | $ |
|
|
|
|
|
30,000
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Collaboration agreement, equity investment receivable | $ |
|
|
|
|
$ 4,800
|
20,200
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Deal value |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
€ 2,700,000,000
|
|
|
|
|
| Janssen | EIB Loan |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Disclosure of transactions between related parties [line items] |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Borrowings, interest rate |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
21.30%
|
|
21.30%
|
|
|
|
|
21.30%
|
|
|
|
|
|
|
|
|
|
| Janssen | Major ordinary share transactions |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Disclosure of transactions between related parties [line items] |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Potential development and commercial milestones payments |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
105,000,000
|
|
|
|
|
| Deal value |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
2,600,000,000
|
|
|
|
|
| Janssen | First Tranche |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Disclosure of transactions between related parties [line items] |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Collaboration agreement, equity investment receivable | $ |
|
|
|
|
|
5,000
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Janssen | Second Tranche |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Disclosure of transactions between related parties [line items] |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Collaboration agreement, equity investment receivable | $ |
|
|
|
|
|
$ 25,000
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Janssen | Top of Range |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Disclosure of transactions between related parties [line items] |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Potential development and commercial milestones payments | $ |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
$ 650,000
|
|
|
|
| Collaboration agreement, compensation per indication | $ |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
220,000
|
|
|
|
| Janssen | Top of Range | Nanobiotix Corp. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Disclosure of transactions between related parties [line items] |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Collaboration agreement, compensation per indication |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
€ 220,000,000
|
$ 220,000
|
|
|
|
| LianBio, NBTXR3 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Disclosure of transactions between related parties [line items] |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Upfront payment received | $ |
|
|
|
|
|
|
|
|
|
|
$ 20,000
|
|
|
|
|
|
|
|
|
|
20,000
|
|
|
|
|
|
|
|
|
|
|
| Upfront payment |
|
|
|
€ 20,000,000
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Collaboration agreement, amount collected |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
€ 100,000
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| LianBio, NBTXR3 | Maximum |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Disclosure of transactions between related parties [line items] |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Potential development and commercial milestones payments | $ |
|
|
|
|
|
|
|
|
|
|
$ 205,000
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| LianBio, NBTXR3 | Maximum |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Disclosure of transactions between related parties [line items] |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Potential development and commercial milestones payments | $ |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
$ 205,000
|
|
|
$ 225,000
|
|
|
|
|
|
|
|
| Termination of PharmaEngine License and Collaboration Agreement, NBTXR3 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Disclosure of transactions between related parties [line items] |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Upfront payment | $ |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
$ 6,500
|
|
|
|
|
|
|
|
|
|
|
|
| Contractual commitments, cumulative payments | $ |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
$ 6,500
|
|
| Milestone payment upon receipt of clinical study reports | $ |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
$ 1,000
|
|
|
$ 1,000
|
|
|
|
|
|
|
|
|
|
|
|
|
| Milestone payment upon second regulatory approval | $ |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
$ 5,000
|
|
|
|
|
|
|
|
|
|
| Royalties agreement, period |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
10 years
|
10 years
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| MD Anderson Cancer Center, NBTXR3 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Disclosure of transactions between related parties [line items] |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Upfront payment | $ |
|
|
|
|
|
|
|
|
$ 1,000
|
$ 1,000
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Number of patients | patient |
|
|
|
|
|
|
|
|
|
|
312
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Contractual capital commitments | $ |
|
|
|
|
|
|
|
|
|
$ 11,000
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Milestone payment, deferment period |
|
|
|
|
|
|
|
|
|
|
|
|
6 months
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Prepaid expenses |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
€ 1,100,000
|
|
€ 1,200,000
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|