75000 - Document - Document And Entity Information
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75010 - Statement - Consolidated Balance Sheets
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75020 - Statement - Consolidated Balance Sheets (Parenthetical)
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75030 - Statement - Consolidated Statements of Operations and Comprehensive Loss
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75040 - Statement - Consolidated Statements of Changes in Convertible Preferred Stock and Stockholders' Equity (Deficit)
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75050 - Statement - Consolidated Statements of Cash Flows
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995457 - Disclosure - Cybersecurity Risk Management, Strategy and Governance
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995467 - Disclosure - Description of Business, Organization and Liquidity
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995477 - Disclosure - Summary of Significant Accounting Policies
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995487 - Disclosure - Reverse Merger
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995497 - Disclosure - Fair Value Measurements
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995507 - Disclosure - Strategic Agreements
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995517 - Disclosure - Accrued Expenses and Other Current Liabilities
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995527 - Disclosure - Convertible Notes Payable
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995537 - Disclosure - Convertible Preferred Stock
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995547 - Disclosure - Stockholders' Equity
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995557 - Disclosure - Equity Incentive Plans
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995567 - Disclosure - Operating Lease Commitments
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995577 - Disclosure - Income Taxes
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995587 - Disclosure - Commitments and Contingencies
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995597 - Disclosure - Net (Loss) Income Per Share
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995607 - Disclosure - Segment Information
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995617 - Disclosure - Subsequent Events
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995627 - Disclosure - Summary of Significant Accounting Policies (Policies)
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995637 - Disclosure - Reverse Merger (Tables)
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995647 - Disclosure - Fair Value Measurements (Tables)
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995657 - Disclosure - Accrued Expenses and Other Current Liabilities (Tables)
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995667 - Disclosure - Convertible Notes Payable (Tables)
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995677 - Disclosure - Equity Incentive Plans (Tables)
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995687 - Disclosure - Operating Lease Commitments (Tables)
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995697 - Disclosure - Income Taxes (Tables)
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995707 - Disclosure - Net (Loss) Income Per Share (Tables)
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995717 - Disclosure - Segment Information (Tables)
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995727 - Disclosure - Description of Business, Organization and Liquidity - Additional Information (Details)
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995737 - Disclosure - Summary of Significant Accounting Policies - Additional Information (Details)
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995747 - Disclosure - Reverse Merger - Additional Information (Details)
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995757 - Disclosure - Reverse Merger - Schedule of Fair Value of Identifiable Assets Acquired and Liabilities Assumed (Details)
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995767 - Disclosure - Fair Value Measurements - Schedule of Financial Assets and Liabilities Measured at Fair Value on a Recurring Basis (Details)
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995777 - Disclosure - Fair Value Measurements - Schedule of Fair Value Measurement Key Assumptions (Details)
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995787 - Disclosure - Fair Value Measurements - Fair Value Measurement Derivative Liabilities (Details)
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995797 - Disclosure - Strategic Agreements - Additional Information (Details)
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995807 - Disclosure - Accrued Expenses and Other Current Liabilities - Schedule of Accrued Expenses and Other Current Liabilities (Details)
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995817 - Disclosure - Accrued Expenses and Other Current Liabilities - Schedule of Accrued Expenses and Other Current Liabilities (Parenthetical) (Details)
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995827 - Disclosure - Convertible Notes Payable - Schedule of Convertible Notes Payable (Details)
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995837 - Disclosure - Convertible Notes Payable - Additional Information (Details)
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995847 - Disclosure - Convertible Preferred Stock - Additional Information (Details)
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995857 - Disclosure - Stockholders' Equity - Additional Information (Details)
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995867 - Disclosure - Equity Incentive Plans - Additional Information (Details)
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995877 - Disclosure - Equity Incentive Plans - Schedule of Stock Options Activity (Details)
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995887 - Disclosure - Equity Incentive Plans - Schedule of Stock-based Compensation Expense Recognized (Details)
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995897 - Disclosure - Equity Incentive Plans - Schedule of Weighted Average Fair Value Of Stock Options Granted (Details)
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995907 - Disclosure - Operating Lease Commitments - Additional Information (Details)
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995917 - Disclosure - Operating Lease Commitments - Schedule of Components of Lease Cost (Details)
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995927 - Disclosure - Operating Lease Commitments - Schedule of Weighted Average Remaining Lease Life And Weighted Average Discount Rate (Details)
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995937 - Disclosure - Operating Lease Commitments - Schedule of Future Minimum Rental Payments Due Under Non-cancelable Leases (Details)
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995947 - Disclosure - Operating Lease Commitments - Schedule of Future Minimum Rental Payments Due Under Non-cancelable Leases (Details) 2
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995957 - Disclosure - Income Taxes - Additional Information (Details)
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995967 - Disclosure - Income Taxes - Schedule of Loss Before Income Taxes (Details)
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995977 - Disclosure - Income Taxes - Schedule of Company's Effective Tax Rate (Details)
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995987 - Disclosure - Income Taxes - Schedule of Company's Effective Tax Rate (Details) 2
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995997 - Disclosure - Income Taxes - Schedule of Deferred Tax Assets (Details)
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996007 - Disclosure - Commitments and Contingencies - Additional Information (Details)
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996017 - Disclosure - Commitments and Contingencies - Schedule of Minimum Lease Payments Due (Details)
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996027 - Disclosure - Net (Loss) Income Per Share - Schedule of Basic and Diluted Net (Loss) Income Per Share (Details)
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996037 - Disclosure - Net (Loss) Income Per Share - Schedule of Potentially Dilutive Securities Excluded from Calculation of Weighted-Average Shares of Common Stock Outstanding (Details)
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996047 - Disclosure - Net (Loss) Income Per Share - Schedule of Potentially Dilutive Securities Excluded from Calculation of Weighted-Average Shares of Common Stock Outstanding (Parenthetical) (Details)
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996057 - Disclosure - Segment Information - Additional Information (Details)
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996067 - Disclosure - Segment Information - Schedule of Reconciles Segment Direct Profit or Loss (Details)
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996077 - Disclosure - Subsequent Events - Additional Information (Details)
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Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Forfeitures and Expirations in Period, Weighted Average Exercise Price
Weighted Average Exercise Price Per Share, Forfeited / Cancelled
Agreement Royalty Term Period From First Sale
Agreement royalty term period from first sale.
Agreement royalty term period from first sale
Income (Loss) from Continuing Operations before Income Taxes, Foreign
Foreign
Measurement Input Probability Rate of Achieving F D A Approval of A Product [Member]
Measurement input probability rate of achieving FDA approval of a product.
Probability rate of achieving FDA approval of a product
Balance, beginning of period
Balance, end of the period
Fair Value, Net Derivative Asset (Liability) Measured on Recurring Basis with Unobservable Inputs
Balance, beginning of period
Balance, end of the period
Entity Incorporation, State or Country Code
Preferred Stock, Shares Issued (in shares)
Preferred stock, shares issued (in shares)
Temporay Equity Stock Issued During Period Shares NewIssues
Temporay equity stock issued during period shares newIssues
Convertible preferred stock issued during period, shares, new issues (in shares)
Convertible Note Issuance Eight [Member]
Convertible note issuance eight.
Note 8
Plan Name [Axis]
Equity [Abstract]
Entity Current Reporting Status
Issuance Date
Debt Instrument, Issuance Date
Operating expenses
Fair Value, Inputs, Level 2 [Member]
Level 2 [Member]
us-gaap_DeferredTaxAssetsNet
Net deferred tax
Commitments and Contingencies
Commitments and Contingencies Disclosure [Text Block]
Common Stock, Shares Authorized (in shares)
Number of authorized to issue shares of common stock
Common stock, shares authorized (in shares)
Other Nonoperating Income (Expense) [Member]
Other [Member]
Convetible preferred stock, par or stated value per share (in dollars per share)
Original Issue Price Per Share
Convertible preferred stock, par value (in dollars per share)
Document Fiscal Period Focus
Operating Lease, Right-of-Use Asset, Statement of Financial Position [Extensible Enumeration]
Debt Instrument, Interest Rate, Stated Percentage
Interest rate
Entity Shell Company
Shares of Palvella convertible preferred stock outstanding
Outstanding Shares
Temporary Equity, Balance (in shares)
Temporary Equity, Balance (in shares)
Convertible preferred stock, shares outstanding (in shares)
Convertible Notes Payable
Convertible Notes Payable Disclosure [Text Block]
Convertible notes payable.
Convertible Debt [Member]
Convertible Debt [Member]
Convertible Note Issuance Two [Member]
Convertible note issuance two.
Note 2
Segment Reporting, Policy [Policy Text Block]
Segments
Cash and Cash Equivalent
Cash and Cash Equivalents, at Carrying Value, Total
Cash and cash equivalents
Stock Issued During Period, Value, Conversion of preferred stock
Stock Issued During Period, Value, Conversion of preferred stock.
Conversion of preferred stock into common stock
Grant proceeds
Government Assistance, Operating Income, Increase (Decrease)
Purchase Agreement [Member]
Purchase agreement.
Purchase Agreement [Member]
Stock Issued During Period, Shares, Conversion of Units
Conversion of common stock
Cybersecurity Risk Management, Strategy, and Governance [Abstract]
Common stock, shares, issued (in shares)
Common stock, shares issued (in shares)
Cybersecurity Risk Management Positions or Committees Responsible Report to Board [Flag]
Cybersecurity Risk Board of Directors Oversight [Text Block]
Short-Term Debt [Table]
Statement [Table]
Internal Revenue Service (IRS) [Member]
Internal Revenue Service (IRS) [Member]
Weighted average fair value of stock options granted
Share-based compensation arrangement by share-based payment award, options, vested, weighted average grant date fair value (in dollars per share)
us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardPurchasePriceOfCommonStockPercent
Percent of option exercise price
Statement [Line Items]
Business Combination [Domain]
Other Expense [Member]
Other [Member]
Entity Filer Category
us-gaap_LiabilitiesAndStockholdersEquity
Total liabilities and stockholders' equity
Business Combination, Recognized Liability Assumed, Liability, Current
Total current liabilities
Debt Instrument [Line Items]
Payables and Accruals [Abstract]
Reduction of Royalty Tier Percentage on Annual Worldwide Net Sales
Reduction of royalty tier percentage on annual worldwide net sales.
Reduction of royalty tier percentage on annual worldwide net sales
Exercisable, exercise price (in dollars per share)
Weighted Average Exercise Price Per Share, Exercisable
us-gaap_ValuationAllowanceDeferredTaxAssetChangeInAmount
Valuation Allowance, Deferred Tax Asset, Increase (Decrease), Amount
Decrease (increase) in valuation allowance
(Increase) decrease in valuation allowance
QTORIN Rapamycin for Microcystic LM [Member]
QTORIN rapamycin for microcystic LM.
us-gaap_BusinessAcquisitionPercentageOfVotingInterestsAcquired
Business Acquisition, Percentage of Voting Interests Acquired
Stockholders owned voting rights percentage
Cybersecurity Risk Third Party Oversight and Identification Processes [Flag]
Money market funds, included in cash equivalents
Money market funds
Cash and cash equivalents
us-gaap_DeferredTaxAssetsValuationAllowance
Valuation allowance
Valuation allowance
Federal income tax rate
U.S. federal statutory rate
us-gaap_SharesIssuedPricePerShare
Shares issued, price per share (in dollars per share)
Exchange ratio
Subsequent Event [Line Items]
Effective Income Tax Rate Reconciliation, Nondeductible Expense, Amount
Effective Income Tax Rate Reconciliation, Nondeductible Expense, Amount, Total
Nontaxable or nondeductible items
Cybersecurity Risk Management Third Party Engaged [Flag]
Documents Incorporated by Reference [Text Block]
Documents Incorporated by Reference
Term period for option to purchase additional product revenue participation rights
Term Period for Option to Purchase Additional Product Revenue Participation Rights
Term period for option to purchase additional product revenue participation rights.
us-gaap_EffectiveIncomeTaxRateContinuingOperations
Effective income tax rate
Stock Options to Purchase Common Stock [Member]
Percentage Of Weighted Average Cost Capital
Percentage of weighted average cost capital.
Weighted average cost of capital
Income Tax Authority [Axis]
Proceeds from Convertible Debt
Proceeds from issuance of convertible notes
Derivative, assumption
Derivative Liability, Measurement Input
Derivative Liability, Measurement Input
QTORIN Rapamycin for Microcystic LM - Government Grant Income [Member]
QTORIN rapamycin for microcystic LM - Government grant income.
Net Income (Loss) Available to Common Stockholders, Basic [Abstract]
Numerator:
Effective Interest Rate Percentage of Potential Future Royalty Payments
Effective interest rate percentage of potential future royalty payments.
Effective interest rate percentage of potential future royalty payments
Conversion of Stock, Amount Converted
Conversion of preferred stock into common stock of Company in connection with Reverse Merger
Summary of Significant Accounting Policies
Significant Accounting Policies [Text Block]
Convertible note issuance Thirteen [Member]
Convertible note issuance thirteen.
Note 13
Transactions costs associated with the Reverse Merger
Adjustments to Additional Paid in Capital, Transactions costs
Adjustments to Additional Paid in Capital, Transactions costs.
Non cash lease operating expense
Non cash lease operating expense.
Non-cash lease operating expense
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Grants in Period, Gross (in shares)
Share-based compensation arrangement by share-based payment award, options, grants in period, gross (in shares)
Common Shares Underlying Stock Options, Granted
Cybersecurity Risk Management, Strategy, and Governance [Table]
Schedule of Earnings Per Share, Basic and Diluted [Table Text Block]
Schedule of Basic and Diluted Net (Loss) Income Per Share
Consultants [Member]
Consultants.
us-gaap_EarningsPerShareBasic
Earnings Per Share, Basic, Total
Net (loss) income per share, basic
Net loss per share of Common Stock - basic (in dollars per share)
Other Comprehensive Income (Loss), Foreign Currency Transaction and Translation Adjustment, Net of Tax
Other Comprehensive Income (Loss), Foreign Currency Transaction and Translation Adjustment, Net of Tax, Total
Foreign currency translation gain
us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber
Common Shares Underlying Stock Options, Outstanding balance
Common Shares Underlying Stock Options, Outstanding balance
Deferred Tax Liabilities, Right Of Use Assets
Deferred tax liabilities, right of use assets
Right of use assets
Right of use assets
Business Combination, Recognized Asset Acquired, Asset, Current
Total current assets
us-gaap_LiabilitiesCurrent
Total current liabilities
Prefunded Warrants [Member]
Pre-funded warrants.
Prefunded warrants to purchase common stock
Prefunded Warrants [Member]
Increase (Decrease) in Accounts Receivable
Accounts receivable
Adjustments to reconcile net (loss) income to net cash used in operating activities:
Lessee, Operating Lease, Liability, to be Paid, Year Five
2030
Covertible notes payable
Convertible Notes Payable, Noncurrent
Convertible Note Issuance Eleven [Member]
Convertible note issuance eleven.
Note 11
Convertible Note Issuance Nine [Member]
Convertible note issuance nine.
Note 9
Domestic Tax Authority [Member]
Royalty Agreements [Member]
Royalty Agreement [Member]
Merger Agreement Closing Date
Merger agreement closing date
Merger agreement closing date.
Percentage Of Taxable Income And Trade Profit
Percentage of taxable income and trade profit.
Percentage of taxable income and trade profit
Stockholders’ equity:
Stockholders' equity:
Entity Small Business
Accumulated deficit
Retained Earnings (Accumulated Deficit)
Retained Earnings (Accumulated Deficit), Total
Accumulated deficit
Deferred Tax Assets, Tax Deferred Expense, Compensation and Benefits, Share-Based Compensation Cost
Stock-based compensation
Amended Ligand Agreement [Member]
Amended Ligand Agreement.
Preferred Stock [Member]
Preferred Stock [Member]
Entity Well-known Seasoned Issuer
Potential future royalty payment
Potential future royalty payment.
Sale of Stock, Price Per Share
Sale of stock, price per share
Merger Agreement And Recapitalization [Text Block]
Merger agreement and recapitalization.
Reverse Merger
Relating to corporate income tax
Corporate Income Tax [Member]
Corporate Income Tax [Member]
Share-Based Payment Arrangement [Text Block]
Equity Incentive Plans
Organization, Consolidation and Presentation of Financial Statements [Abstract]
Leases [Abstract]
Amendment Flag
Effective Income Tax Rate Reconciliation at Federal Statutory Income Tax Rate, Amount
U.S. federal statutory rate
Class of Warrant or Right, Number of Securities Called by Warrants or Rights
Class of warrant or right, number of securities called by warrants or rights (in shares)
Number of pre-funded warrants outstanding to purchase common stock
Preferred Stock Dividends Accrued But Not Declared Income Statement Impact
Preferred stock dividends accrued but not declared income statement impact
Less non-cumulative preferred Series C dividends accrued but not declared during the period
Less non-cumulative preferred Series C dividends accrued but not declared during the period
Earnings Per Share, Policy [Policy Text Block]
Net Loss Per Share
Entity Address, Postal Zip Code
Accounts Receivable
Accounts Receivable [Policy Text Block]
us-gaap_NetCashProvidedByUsedInOperatingActivities
Net cash used in operating activities
Net cash used in operating activities
Segment Reporting, CODM, Profit (Loss) Measure, How Used, Description
Common Stock [Member]
Common Stock [Member]
Pipe finance.
Pipe Finance [Member]
PIPE Financing [Member]
Cybersecurity Risk Role of Management [Text Block]
us-gaap_TaxCreditCarryforwardAmount
Tax credit carryforward, amount
Granted, exercise price (in dollars per share)
Weighted Average Exercise Price Per Share, Granted
2028
Lessee, Operating Lease, Liability, to be Paid, Year Three
Government Assistance, Income, Increase (Decrease)
Government Assistance, Income, Increase (Decrease), Total
Grant income
Entity Address, Address Line One
Schedule of Share-Based Payment Award, Stock Options, Valuation Assumptions [Table Text Block]
Schedule of Weighted Average Fair Value of Stock Options Granted
Fair Value Hierarchy and NAV [Axis]
Net loss per share
Net (loss) income per share of common stock (Note 13):
Income Tax, Policy [Policy Text Block]
Income Taxes
Temporary Equity, Carrying Amount, Attributable to Parent
Temporary Equity, Balance
Temporary Equity, Balance
Convertible preferred stock, $0.00001 par value; 0 and 20,655,895 shares authorized; 0 and 15,360,787 shares issued and outstanding at December 31, 2024 and 2023; aggregate liquidation value of $0 and $65,377 at December 31, 2024 and 2023
Cybersecurity Risk Materially Affected or Reasonably Likely to Materially Affect Registrant [Flag]
Supplemental Cash Flow Information [Abstract]
SUPPLEMENTARY DISCLOSURE OF NONCASH FINANCING ACTIVITIES:
Foreign Currency Transactions and Translations Policy [Policy Text Block]
Foreign Currency Translation
Right-of-use assets
Operating Lease, Right-of-Use Asset
Operating lease right-of-use assets, net
us-gaap_DeferredTaxAssetsGross
Deferred tax assets before valuation allowance
Cybersecurity Risk Board Committee or Subcommittee Responsible for Oversight [Text Block]
Class of Warrant or Right [Axis]
Exchange ratio
Exchange Ratio
Exchange Ratio
Document Type
Collaborative Arrangement and Arrangement Other than Collaborative [Axis]
Collaborative Arrangement and Arrangement Other than Collaborative [Domain]
Entity Central Index Key
Cybersecurity Risk Process for Informing Board Committee or Subcommittee Responsible for Oversight [Text Block]
us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect
Net (decrease) increase in cash and cash equivalents
Subsequent Event Type [Domain]
Conversion of convertible notes into common stock of Company in connection with Reverse Merger
Conversion of Convertible Notes Into Common Stock of Company in Connection with Reverse Merger
Conversion of convertible notes into common stock of company in connection with reverse merger.
us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount
Antidilutive Securities Excluded from Computation of Earnings Per Share, Amount (in shares)
Antidilutive securities excluded from computation of earnings per share
Non cash interest expense convertible notes.
Non Cash Interest Expense Convertible Notes
Non-cash interest expense - convertible notes
Related Party Transactions [Policy Text Block]
Related party transactions.
Related Party Transactions
Common Stock, Par or Stated Value Per Share (in dollars per share)
Common stock, par value (in dollars per share)
Liabilities [Abstract]
Outstanding, contractual life (Year)
Weighted Average Remaining Contractual Life (in years)
Expected volatility, maximum
Expected volatility, Maximum
Document Financial Statement Error Correction [Flag]
Issuance of common stock resulting from exercise of stock options (in shares)
Common Shares Underlying Stock Options, Exercised
Common Shares Underlying Stock Options, Exercised
Exercise of common stock options for cash, net of expense (in shares)
Fair Value Adjustments on Derivative Liabilities Contingent Value Right Liability
Fair value adjustments on derivative liabilities contingent value right liability.
Fair value adjustments on derivative liabilities - contingent value right liability
Convertible Notes [Policy Text Block]
Convertible notes.
Convertible Notes
Stock Issued During Period, Shares, Conversion of Convertible note
Stock issued during period, shares, conversion of convertible note.
Conversion of convertible notes into common stock and prefunded warrants in connection with Reverse Merger (in shares)
Current Fiscal Year End Date
Convertible Notes Payable
Convertible Notes Payable
Convertible Notes Payable, Total
Trade Tax [Member]
Relating to trade tax
Trade Tax [Member]
Entity Address, State or Province
Stock Issued During Period, Value, Conversion of Convertible Securities
Conversion of convertible preferred stock into common stock in connection with Reverse Merger
Preferred Stock, Shares Outstanding, Ending Balance
Preferred Stock, Shares Outstanding, Beginning Balance
Preferred Stock, Shares Outstanding (in shares)
Preferred stock, shares outstanding (in shares)
Comprehensive Income (Loss), Net of Tax, Attributable to Parent
Comprehensive loss
Research and Development Expense, Policy [Policy Text Block]
Research and Development Expenses
Shares available for future grants
Common stock, capital shares reserved for future issuance (in shares)
Fair Value, Net Derivative Asset (Liability), Recurring Basis, Unobservable Input Reconciliation, Gain (Loss), Statement of Income or Comprehensive Income [Extensible Enumeration]
Incremental Common Shares Attributable to Dilutive Effect of Share-Based Payment Arrangements
Stock options
Class of Warrant or Right [Domain]
Transaction costs incurred
Business Combination, Transaction Cost, Excluding Separately Recognized Transaction
Upfront Payment
Upfront payment.
Upfront payment
Conversion of stock, shares converted
Conversion of Stock, Shares Converted
Conversion of stock, shares converted
Convertible Note Issuance One [Member]
Convertible note issuance one.
Note 1
Stock issued during period, value, conversion of convertible note
Stock issued during period, value, conversion of convertible note.
Conversion of convertible notes into common stock and prefunded warrants in connection with Reverse Merger
Schedule of Stock-based Compensation Expense Recognized
Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Table Text Block]
Stock Issued During Period, Value, Stock Options Exercised
Exercise of common stock options for cash, net of expense
Accounts Payable, Accrued Liabilities, and Other Liabilities Disclosure, Current [Text Block]
Accrued Expenses and Other Current Liabilities
Schedule of Deferred Tax Assets and Liabilities [Table Text Block]
Schedule of Deferred Tax Assets
Other Comprehensive Income (Loss), Net of Tax [Abstract]
Other comprehensive loss:
Subsequent Event [Member]
Subsequent Event [Member]
Fair Value Measurement Inputs and Valuation Techniques [Table]
Measurement Input, Expected Term [Member]
Expected term to FDA regulatory approval of a product
Gain (Loss) on Contract Termination
Gain on extinguishment
Gain on extinguishment - royalty agreement
Proceeds from Issuance of Convertible Preferred Stock
Proceeds from issuance of convertible preferred stock
Antidilutive Securities [Axis]
Business Combination, Recognized Asset Acquired, Prepaid Expense and Other Asset, Current
Prepaid expenses and other current assets
Interest Expense, Debt
Interest Expense, Debt, Total
Interest expense - convertible notes payable
Relating to Series A through E Preferred stock
Series A Through E [Member]
Payments of Transaction Costs Associated with Pipe Financing
Payments of transaction costs associated with pipe financing.
Payments of transaction costs associated with PIPE Financing
Orphan drug credits
Operating Loss Carry forwards Orphan Drug Tax Credit Carry forward
Operating loss carry forwards orphan drug tax credit carry forward.
Comprehensive (Loss) Income and Accumulated Other Comprehensive (Loss) Income [Policy Text Block]
Comprehensive (loss) income and accumulated other comprehensive (loss) income.
Comprehensive Loss and Accumulated Other Comprehensive (Loss) Income
State and Local Jurisdiction [Member]
Accumulated Other Comprehensive Income [Member]
AOCI Attributable to Parent [Member]
Lessee, Operating Lease, Option to Extend
Lease option to extend
Stockholder's Equity [Table]
Stockholder's Equity
Preferred Stock, Value, Issued
Preferred stock, $0.001; 10,000,000 shares authorized; 0 and 15,617 shares issued and outstanding at December 31, 2025 and 2024
Cash Acquired from Reverse Merger transaction
Cash acquired from Reverse Merger transaction.
Cash acquired from Reverse Merger transaction
Debt Instrument, Maturity Date
Debt instrument maturity date
Minimum [Member]
Minimum
Current assets:
Royalty Percentage
Royalty percentage.
Royalty percentage
Fair Value, Inputs, Level 3 [Member]
Level 3 [Member]
Liabilities, Fair Value Disclosure [Abstract]
Liabilities:
Segment Reporting [Abstract]
Business Combination, Recognized Asset Acquired, Asset
Total assets
Total assets
Schedule of Fair Value, Assets and Liabilities Measured on Recurring Basis [Table Text Block]
Schedule of Financial Assets and Liabilities Measured at Fair Value on a Recurring Basis
Current liabilities:
Business Combination, Recognized Asset Acquired, Asset, Current [Abstract]
Current assets:
us-gaap_SharesOutstanding
Balance (in shares)
Balance (in shares)
us-gaap_OperatingLossCarryforwards
Operating loss carryforwards
Accounts Receivable, after Allowance for Credit Loss, Current
Accounts Receivable, after Allowance for Credit Loss, Current, Total
Accounts receivable
Commitments and Contingencies
Commitments and contingencies (Note 9)
Royalty agreement liabilities
Deferred Tax Assets, Royalty Agreement Liabilities
Deferred tax assets, royalty agreement liabilities.
Lessee, Leases [Policy Text Block]
Leases
General and Administrative Expense [Member]
General and administrative
Operating Lease, Liability
Lease liabilities
Subtotal
Payments of Merger Related Costs, Financing Activities
Payment of transaction costs in connection with Reverse Merger
Auditor Firm ID
Change in valuation allowance
Change in valuation allowance
Lessor, Operating Lease, Lease Not yet Commenced, Assumption and Judgment, Value of Underlying Asset, Amount
Leases not yet commenced
Effect of Exchange Rate on Cash, Cash Equivalent, Restricted Cash, and Restricted Cash Equivalent, Including Discontinued Operation
Effect of Exchange Rate on Cash, Cash Equivalents, Restricted Cash, and Restricted Cash Equivalents, Including Disposal Group and Discontinued Operations, Total
Effect of exchange rate change on cash and cash equivalents
Interest Income (Expense), Operating
Interest Income (Expense), Operating, Total
Interest income, net
Non-voting Common Stock [Member]
Non-voting Common Stock [Member]
Business Combination, Recognized Asset Acquired, Cash and Cash Equivalent
Cash
Tax Loss Carryforwards
Tax loss carryforwards.
Tax loss carryforwards
Long-Term Debt, Type [Domain]
Contingent Value Right Liability [Member]
Contingent Value Right Liability Member.
Cybersecurity Risk Management Positions or Committees Responsible [Text Block]
Basic and diluted (in shares)
Weighted-average number of shares outstanding used in computing net income (loss) per share - basic
Weighted-average number of shares outstanding used in computing net income (loss) per share - basic
Weighted-average shares used in computing net loss per share of Common Stock - basic (in shares)
Document Information [Line Items]
Temporary Equity [Abstract]
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Intrinsic Value
Aggregate intrinsic value of options exercisable
Schedule of Effective Income Tax Rate Reconciliation [Table Text Block]
Schedule of Company's Effective Tax Rate
Schedule of Share-Based Compensation Arrangements by Share-Based Payment Award [Table]
Cybersecurity Risk Process for Informing Management or Committees Responsible [Text Block]
us-gaap_ProceedsFromIssuanceOfPrivatePlacement
Proceeds from issuance of private placement
Proceeds from PIPE Financing
Subsequent Events
Subsequent Events [Text Block]
Effective Income Tax Rate Reconciliation, Tax Credit, Percent
Effective Income Tax Rate Reconciliation, Tax Credit, Percent, Total
Tax credits
Tax credits
Income Tax Examination, Year under Examination
Income tax examination year
Series A-1 Preferred Stock [Member]
Series A One Preferred Stock [Member]
Series A One Preferred Stock.
Stock based compensation expense
Stock-based compensation
Variable Rate [Domain]
Effective Income Tax Rate Reconciliation, Change in Deferred Tax Assets Valuation Allowance, Amount
Change in valuation allowance
us-gaap_StockholdersEquity
Balance
Balance
Total stockholders' equity
Preferred Stock, Par or Stated Value Per Share (in dollars per share)
Preferred stock, par value (in dollars per share)
Basis of Accounting, Policy [Policy Text Block]
Basis of Presentation
Interest Income Expense Nonoperating Royalty Agreement
Interest income expense nonoperating royalty agreement.
Interest expense - royalty agreement
Statement of Stockholders' Equity [Abstract]
Series C Preferred Stock [Member]
Merger Agreement [Member]
Merger agreement.
Merger Agreement [Member]
Series A Preferred Stock [Member]
Use of Estimates
Use of Estimates, Policy [Policy Text Block]
Accrued Severance, Bonus, And Retention Costs, Current
Accrued severance, bonus, and retention costs, current.
Accrued severance, bonus, and retention
Over-Allotment Option [Member]
Underwritten Public Offering [Member]
Business Combination, Recognized Identifiable Assets Acquired and Liabilities Assumed, Accrued expenses and other current liabilities
Business Combination, Recognized Identifiable Assets Acquired and Liabilities Assumed, Accrued expenses and other current liabilities.
Accrued expenses and other current liabilities
Entity Address, Address Line Two
Fair Value Disclosures [Text Block]
Fair Value Measurements
ConvertiblePreferredStockBeneficialOwnershipLimitationPercent
Percentage of beneficial ownership limitation for convertible preferred stock
Convertible preferred stock, common stock ownership limit, percent
Debt Instrument, Name [Domain]
Measurement Input, Discount Rate [Member]
Discount rate [Member]
Segment Reporting, CODM, Individual Title and Position or Group Name [Extensible Enumeration]
Plan Name [Domain]
Fair Value, Net Derivative Asset (Liability) Measured on Recurring Basis, Unobservable Inputs Reconciliation, Gain (Loss) Included in Earnings
Fair value adjustments on derivative liabilities
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Entity [Domain]
Research And Development Expenses (Income)
Research and development expenses (income).
Total research and development
Cybersecurity Risk Materially Affected or Reasonably Likely to Materially Affect Registrant [Text Block]
Business Description and Basis of Presentation [Text Block]
Description of Business, Organization and Liquidity
Cybersecurity Risk Management Expertise of Management Responsible [Text Block]
Business Combination, Recognized Liability Assumed, Liability [Abstract]
Liabilities
Effective Income Tax Rate Reconciliation, Other Adjustments, Amount
Other adjustments
Ligand Development Funding Agreement [Member]
Ligand Development Funding Agreement.
Startup costs
Deferred Tax Assets, Startup Costs
Deferred tax assets, startup costs.
Foreign Tax Authority [Member]
Foreign Tax Jurisdiction [Member]
Accounting Standards Update [Extensible Enumeration]
Entity Address, City or Town
Number of reportable segments
Number of Reportable Segments
Security Exchange Name
Debt Instrument, Variable Interest Rate, Type [Extensible Enumeration]
Other
Other adjustments
Counterparty Name [Axis]
Income (Loss) from Continuing Operations before Income Taxes, Noncontrolling Interest
Loss before income taxes
Measurement Input Type [Domain]
Antidilutive Securities, Name [Domain]
Effective Income Tax Rate Reconciliation, Foreign Income Tax Rate Differential, Percent
Foreign tax effects
Stockholders' Equity Note [Abstract]
Debt Instrument, Increase, Accrued Interest
Accrued interest
Government Grants [Policy Text Block]
Government grants.
Government Grants
Statistical Measurement [Domain]
Class of Warrant or Right, Exercise Price of Warrants or Rights
Class of warrant or right, exercise price of warrants or rights (in dollars per share)
us-gaap_AssetsCurrent
Total current assets
Share-based payment arrangement expense
Stock-based compensation expense
Convertible Note Issuance Seventeen [Member]
Convertible Note Issuance Seventeen.
Note 17
Document Period End Date
Fair Value Hierarchy and NAV [Domain]
ICFR Auditor Attestation Flag
Reverse Merger [Abstract]
Reverse Merger
Milestone Closing [Member]
Milestone Closing.
Exercisable, balance (in shares)
Common Shares Underlying Stock Options, Exercisable
Other Comprehensive Income (Loss), Foreign Currency Transaction and Translation Gain (Loss) Arising During Period, Net of Tax
Foreign currency translation gain
Payment of transaction costs to issue convertible notes
Payment of Transaction Costs to Issue Convertible Notes
Payment of transaction costs to issue convertible notes.
Accrued Research and Development Expenses Current
Accrued research and development expenses current.
Research and development expenses
Operating Lease, Liability, Current, Statement of Financial Position [Extensible Enumeration]
Statement of Financial Position [Abstract]
Business Combination, Recognized Asset Acquired, Asset [Abstract]
Assets
Antidilutive Security, Excluded EPS Calculation [Table]
Class of Stock [Axis]
Deferred Tax Liabilities, Net
Deferred Tax Liabilities, Net, Total
Liabilities for unrecognized tax benefits
us-gaap_CurrentIncomeTaxExpenseBenefit
Current income tax expense (benefit)
Current income tax expense (benefit)
Cybersecurity Risk Management, Strategy, and Governance [Line Items]
Income Taxes [Table]
Income Taxes [Table]
us-gaap_Liabilities
Total liabilities
Effective Income Tax Rate Reconciliation, Foreign Income Tax Rate Differential, Amount
Foreign tax effects
Palvella Therapeutics Inc [Member]
Palvella Therapeutics Inc [Member].
Palvella Therapeutics, Inc [Member]
Lessee, Operating Lease, Liability, to be Paid, Year Two
2027
Fair Value, Net Derivative Asset (Liability) Measured on Recurring Basis, Unobservable Input Reconciliation [Table]
Variable Rate [Axis]
Convertible Note Issuance Fifteen [Member]
Convertible note issuance fifteen
Note 15
Business Combination, Recognized Liability Assumed, Liability, Current [Abstract]
Current liabilities:
Weighted Average Number of Shares Outstanding, Diluted
Denominator for diluted net income (loss) per share - adjusted weighted average shares
Denominator for diluted net (loss) income per share - adjusted weighted average shares
Weighted-average shares used in computing net loss per share of Common Stock - diluted (in shares)
Entity File Number
Convertible Note Issuance Four [Member]
Convertible note issuance four.
Note 4
Expected volatility, minimum
Expected volatility, Minimum
Measurement Input Type [Axis]
Fair Value Measurement Derivative Liabilities
Fair Value, Net Derivative Asset (Liability) Measured on Recurring Basis, Unobservable Input Reconciliation [Table Text Block]
Prepaid expenses and other current assets
Temporary Equity Stock Issued During Period Value Conversion Of Convertible Securities
Temporary equity stock issued during period value conversion of convertible securities.
Temporary equity, Conversion of convertible preferred stock into common stock in connection with Reverse Merger
Number of Operating Segments
Number of operating segments
Sale of Stock [Domain]
Segment Reporting Disclosure [Text Block]
Segment Information
General and administrative
Total general and administrative
General and Administrative Expense, Total
Series B Preferred Stock [Member]
Stock Issued During Period, Shares, Acquisitions
Issuance of preferred stock and common stock to former stockholders of Pieris in connection with Reverse Merger (in shares)
Canceled, balance (in shares)
Common Shares Underlying Stock Options, Forfeited / Cancelled
Common Shares Underlying Stock Options, Forfeited / Cancelled
Subsequent Event [Table]
Voting Common Stock [Member]
Voting Common Stock.
Lease expiring date
Lessee Operating Lease expiration date
Lessee Operating Lease expiration date.
Business Combination, Recognized Liability Assumed, Accounts Payable, Current
Accounts payable
Short-Term Debt, Type [Domain]
Operating Lease, Expense
Rent expense
Aggregate potential future milestone payments remaining under arrangement
Aggregate Potential Future Milestone Payments Remaining under Arrangement
Aggregate potential future milestone payments remaining under arrangement.
Gain (Loss) on Extinguishment of Debt
Gain (Loss) on Extinguishment of Debt, Total
Gain on extinguishment - royalty agreement
Amount before allocation of valuation allowances of deferred tax asset attributable to capitalized research and development.
Capitalized R&D
Section 174 R&D capitalization
Short-Term Debt, Type [Axis]
New Accounting Pronouncements, Policy [Policy Text Block]
Recently Adopted Accounting Standards
Lessee, Operating Lease, Liability, to be Paid, Maturity [Table Text Block]
Schedule of Future Minimum Rental Payments Due Under Non-cancelable Leases
NumberOfVotesPerShare
Represents the number of votes per share
Number of votes per share
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]
Stock Issued During Period, Shares, Conversion of Convertible Securities
Conversion of convertible preferred stock into common stock in connection with Reverse Merger (in shares)
Share-Based Compensation Arrangement by Share-Based Payment Award, Award Vesting Period
Vesting period
Business Combination, Recognized Liability Assumed, Liability
Total liabilities
Total liabilities
Risk free interest rate, minimum
Risk-free interest rate, Minimum
Income (Loss) from Continuing Operations before Income Taxes, Domestic
Domestic
Income Tax Expense (Benefit), Effective Income Tax Rate Reconciliation, Amount [Abstract]
Amount
us-gaap_LesseeOperatingLeaseTermOfContract
Initial term
Common Stock, Shares Outstanding (in shares)
Common Stock, Shares, Outstanding, Ending Balance
Common Stock, Shares, Outstanding, Beginning Balance
Palvella shares of common stock outstanding
Common stock, shares outstanding (in shares)
Operating Lease, Liability, Current
Less: current portion
Less: current portion
Current portion of operating lease liability
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Cybersecurity Risk Management Processes Integrated [Flag]
Document Transition Report
Deferred Tax Assets, Net
Net deferred tax assets
us-gaap_OperatingExpenses
Total operating expenses
Research and development
Research and Development Expense, Total
Total research and development
Research and development
Convertible Notes Payable [Abstract]
Lessee, Operating Leases [Text Block]
Operating Lease Commitments
PIPE Investors [Member]
P I P E Investors [Member]
PIPE investors.
Convertible Preferred Stock [Member]
Convertible Preferred Stock [Member]
Amount before allocation of valuation allowances of deferred tax asset attributable to deductible temporary differences from lease liability
Lease liability
Lease liabilities
Unrealized Gain (Loss) on Derivatives
Fair value adjustments on derivative liabilities - royalty agreement
Statement of Cash Flows [Abstract]
Weighted Average Number of Shares Outstanding, Diluted, Adjustment [Abstract]
Effect of dilutive securities:
Stock Issued During Period, Value, Conversion of prefunded warrants
Stock Issued During Period, Value, Conversion of prefunded warrants.
Conversion of prefunded warrants into common stock
Share-Based Payment Arrangement, Option, Activity [Table Text Block]
Schedule of Stock Option Activity
Current assets:
Assets, Fair Value Disclosure [Abstract]
Fair Value, Option, Changes in Fair Value, Gain (Loss)
Fair value adjustments on convertible notes payable
Equity [Text Block]
Stockholders' Equity
Strategic Agreements [Text Block]
Strategic agreements.
Strategic Agreements
Earnings Per Share [Text Block]
Net (Loss) Income Per Share
Temporary Equity [Line Items]
Deferred Tax Liabilities, Other
Other deferred tax liabilities
Other deferred tax liabilities
Cybersecurity Risk Management Processes Integrated [Text Block]
Net loss
Net Loss
Aggregate intrinsic value of options outstanding
us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingIntrinsicValue
Outstanding, intrinsic value
Outstanding, intrinsic value
Payments totalling to fund development
Payments Totalling to Fund Development
Payments totalling to fund development.
Additional Amount Received in Return for Increase in Future Tiered Royalties
Additional amount received in return for increase in future tiered royalties.
Additional amount received in return for increase in future tiered royalties
Series E Preferred Stock [Member]
Operating lease costs
Operating lease cost
Convertible Preferred Stock [Text Block]
Convertible preferred stock.
Convertible Preferred Stock
Dividend yield
Expected dividend yield
Stock Issued During Period, shares, Conversion of preferred stock
Stock Issued During Period, shares, Conversion of preferred stock.
Conversion of preferred stock into common stock (in shares)
Assets [Abstract]
Noncash Interest Income Expense Royalty Agreement
Noncash interest income expense royalty agreement.
Non-cash interest expense (income) - royalty agreement
Non-cash interest expense (income)
Non-cash interest expense
Income Tax Authority, Name [Axis]
us-gaap_IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets
Prepaid expenses and other current assets
Government Assistance, Income, Increase (Decrease), Statement of Income or Comprehensive Income [Extensible Enumeration]
Research And Development Tax Credit Receivable
Research and development tax credit receivable.
German research and development tax credit receivable
Document Fiscal Year Focus
Merger Agreement, Stock Exchange Ratio
Merger agreement, stock exchange ratio.
Exchange ratio
Convertible Note Issuance Five [Member]
Convertible note issuance five.
Note 5
Accounts payable
Schedule of Income before Income Tax, Domestic and Foreign [Table Text Block]
Schedule of Loss Before Income Taxes
Research and Development Expense [Member]
Research and development
Research and Development Expense [Member]
Segment Reporting, Factors Used to Identify Entity's Reportable Segments
Convertible Notes Payable [Member]
Convertible Notes [Member]
Convertible Note Issuance Three [Member]
Convertible note issuance three.
Note 3
Schedule of Accrued Expenses and Other Current Liabilities [Table Text Block]
Schedule of accrued expenses and other current liabilities.
Schedule of Accrued Expenses and Other Current Liabilities
Amount before allocation of valuation allowances of deferred tax asset attributable to deductible temporary differences from accrued compensation and other costs
Accrued expenses, tax assets
Accrued expenses and other
Fair Value Measurement, Policy [Policy Text Block]
Fair Value Measurements
Proceeds from exercise of stock options
Proceeds from Stock Options Exercised
Fair Value Disclosures [Abstract]
Commitments and Contingencies Disclosure [Abstract]
Stock Issued During Period, Value, Acquisitions
Issuance of preferred stock and common stock to former stockholders of Pieris in connection with Reverse Merger
Effective Income Tax Rate Reconciliation, Tax Credit, Amount
Effective Income Tax Rate Reconciliation, Tax Credit, Amount, Total
Tax credits
Lessee, Operating Lease, Liability, to be Paid, Year One
2026
Temporary Equity Stock Issued During Period Shares Conversion Of Convertible Securities
Temporary equity stock issued during period shares conversion of convertible securities.
Temporary equity, Conversion of convertible preferred stock into common stock in connection with Reverse Merger (in shares)
Net Income (Loss) Available to Common Stockholders, Basic
(Loss) income available to common stockholders - basic
Net (loss) income attributable to common stockholders
Net (loss) income attributable to common stockholders
Net assets acquired
Business Combination, Recognized Asset Acquired to Liability Assumed, Excess (Less)
Increase Decrease In Fair Value Of Convertible Notes Payable
Increase decrease in fair value of convertible notes payable.
Change in fair value of convertible notes payable
Debt Instrument [Axis]
Derivative Instrument [Axis]
Lessee, Operating Lease, Liability, to be Paid, after Year Five
Thereafter
Share-Based Payment Arrangement [Abstract]
Assets, Fair Value Disclosure
Total assets measured at fair value
Sale of Stock [Axis]
Derivatives, Policy [Policy Text Block]
Derivative Instruments
Government Assistance, Operating Income, Increase (Decrease), Statement of Income or Comprehensive Income [Extensible Enumeration]
Private Placement [Member]
Private Placement [Member]
QTORIN CMC [Member]
QTORIN CMC
Undistributed Earnings (Loss) Allocated to Participating Securities, Basic
Undistributed Earnings (Loss) Allocated to Participating Securities, Basic, Total
Less: allocation of undistributed earnings to participating securities - preferred stock
Less: allocation of undistributed earnings to participating securities - preferred stock
Title of 12(b) Security
Schedule of Segment Reporting Information, by Segment [Table]
Prefund Warrants [Member]
Prefund Warrants.
Prefund Warrants [Member]
Income Tax Disclosure [Text Block]
Income Taxes
Collaborative Arrangement and Arrangement Other than Collaborative [Table]
Convertible preferrd stock, Shares issued (in shares)
Issued Shares
Convertible preferred stock, shares issued (in shares)
Sale Of Stock Number Of Additional Shares Issued In Transaction
Sale of stock, number of additional shares issued in transaction.
Sale of stock, number of additional shares issued in transaction
Document Information [Table]
Legal Entity [Axis]
Convertible Note Issuance Ten [Member]
Convertible note issuance ten.
Note 10
Adjustment to Reconcile Net Income to Cash Provided by (Used in) Operating Activity, Increase (Decrease) in Operating Capital [Abstract]
Change in operating assets and liabilities:
us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice
Weighted Average Exercise Price Per Share, Outstanding balance
Weighted Average Exercise Price Per Share, Outstanding balance
Income Tax Disclosure [Abstract]
Fair Value, Recurring and Nonrecurring [Table]
Unrecognized Tax Benefits
Unrecognized Tax Benefits, Ending Balance
Unrecognized Tax Benefits, Beginning Balance
Unrecognized tax benefits
Additional Paid-in Capital [Member]
Additional Paid-in Capital [Member]
us-gaap_IncreaseDecreaseInAccruedLiabilitiesAndOtherOperatingLiabilities
Accrued expenses and other liabilities
Accrued expenses and other current liabilities
German research and development tax credit receivable
Increase Decrease in German Research and Development Tax Credit Receivables
Increase decrease in research and development tax credit receivables.
Measurement Frequency [Domain]
Operating Lease, Liability, Noncurrent, Statement of Financial Position [Extensible Enumeration]
Statement of Income Location, Balance [Axis]
Trading Symbol
Open Tax Year
Open Tax Year
Proceeds from Notes Payable
Proceeds from Notes Payable, Total
Proceeds from notes payable
Risk free interest rate, maximum
Risk-free interest rate, Maximum
Permanent items
Nontaxable or nondeductible items
Subsequent Event Type [Axis]
Compensation expense
Employee-related Liabilities, Current, Total
Compensation expense
Financing activities:
Cash flows from financing activities
Class of Warrant or Right, Exercise Price, Subtracted Amount From Purchase Price, Per Share
Class of warrant or right, exercise price, subtracted amount from purchase price, per share.
Class of warrant or right, exercise price, subtracted amount from purchase price, per share
Expected term (in years) (Year)
Expected term (years)
Fair Value, Recurring [Member]
Recurring Basis [Member]
Income Taxes [Line Items]
Income Taxes [Line Items]
Lessee, Operating Lease, Liability, to be Paid
Total gross minimum lease payments
Lease Commencement Date
Lease commencement date.
Operating lease commencement date
Lessee, Operating Lease, Liability, Undiscounted Excess Amount
Less: imputed interest
Fair Value Measurement Inputs and Valuation Techniques [Line Items]
Equity Components [Axis]
2024 Equity Incentive Plan
Two Thousand And Twenty Four Equity Incentive Plan [Member]
Two thousand and twenty four equity incentive plan.
Equity Component [Domain]
Schedule of Fair Value of Identifiable Assets Acquired and Liabilities Assumed
Business Combination, Recognized Asset Acquired and Liability Assumed [Table Text Block]
Document Annual Report
Business Combination [Axis]
Issuance of common stock and pre-funded warrants in connection with PIPE, shares
Issuance of common stock and pre-funded warrants in connection with PIPE, shares.
Issuance of common stock and prefunded warrants in connection with PIPE (In Shares)
Share-Based Compensation Arrangement by Share-Based Payment Award, Expiration Period
Options expiration period
ConvertiblePreferredStockBeneficialOwnershipLimitationNoticePeriodBeforeIncrease
Period in which the entity must notify an increase in beneficial ownership limitation.
Convertible preferred stock, beneficial ownership limitation, notice period before increase (Year)
Convertible Note Issuance Fourteen [Member]
Convertible note issuance fourteen.
Note 14
Maximum [Member]
Maximum
Liabilities, Fair Value Disclosure
Total liabilities measured at fair value
Statistical Measurement [Axis]
Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Exercises in Period, Weighted Average Exercise Price
Weighted Average Exercise Price Per Share, Exercised
Common stock, $0.001 par value; 200,000,000 shares authorized; 12,380,933 and 11,012,105 shares issued and outstanding at December 31, 2025 and 2024
Net Income (Loss) Available to Common Stockholders, Diluted
(Loss) income available to common stockholders - diluted
Salaries and Stock-based Compensation [Member]
Salaries and stock-based compensation.
Costs To Issue Convertible Notes Charged To Expense
Costs to issue convertible notes charged to expense.
Costs to issue convertible notes charged to expense
Amount of current portion of expenses incurred but not yet paid nor invoiced, and liabilities classified as other.
Accrued expenses and other current liabilities
Total accrued expenses and other current liabilities
Secured Overnight Financing Rate (SOFR) [Member]
SOFR [Member]
QTORIN Rapamycin For Cutaneous VM [Member]
QTORIN Rapamycin For Cutaneous VM.
Net operating loss carryforwards
Net operating loss
Cybersecurity Risk Management Processes for Assessing, Identifying, and Managing Threats [Text Block]
Tax Credit Carryforward [Axis]
Deferred Costs, Current
Deferred transaction costs
Entity Public Float
Preferred Stock, Shares Authorized (in shares)
Preferred stock, shares authorized (in shares)
Orphan Drug Credits [Member]
Orphan drug credits.
Business Combination [Table]
Entity Registrant Name
Entity Voluntary Filers
Two thousand and Ninteen Equity Incentive Plan [Member]
Two thousand and Ninteen Equity Incentive Plan.
2019 Equity Incentive Plan
Royalty Agreement Liability
Royalty agreement liability.
Royalty agreement liability
Other (expense) income
Other (expense) income, Total
Other income (expense), net
Additional paid-in capital
Series D Preferred Stock [Member]
Series D Preferred Stock [Member]
Conversion of stock, shares issued
Conversion of Stock, Shares Issued
Subsequent Events [Abstract]
Cybersecurity Risk Management Positions or Committees Responsible [Flag]
Income Tax Expense (Benefit)
Income tax benefit (expense)
Effective income tax rate
Measurement Frequency [Axis]
Proceeds from Issuance of Common Stock
Net proceeds from offering, after deducting underwriting discounts and commissions and other estimated offering expenses
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]
Fair Value Measurement Inputs and Valuation Techniques [Table Text Block]
Schedule of Fair Value Measurement Key Assumptions
Entity Common Stock, Shares Outstanding
Concentration Risk, Credit Risk, Policy [Policy Text Block]
Concentration of Credit Risk and Other Risks and Uncertainties
Increase (Decrease) in Derivative Liabilities
Change in fair value of derivative liabilities - royalty agreement
Accumulated Other Comprehensive Income (Loss), Net of Tax
Accumulated Other Comprehensive Income (Loss), Net of Tax, Total
Accumulated other comprehensive (loss) income
Convertible Debt [Table Text Block]
Schedule of Convertible Notes Payable
Transaction Costs Related to Reverse Merger Included in Accounts Payable and Accrued Expenses
Transaction costs related to reverse merger included in accounts payable and accrued expenses.
Transaction costs related to Reverse Merger included in accounts payable and accrued expenses
Other tax credits
Deferred Tax Assets, Tax Credit Carryforwards, Other
Temporary Equity, by Class of Stock [Table]
us-gaap_Assets
Total assets
Series A-2 Preferred Stock [Member]
Series A Two Preferred Stock [Member]
Series A Two Preferred Stock.
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Weighted Average Remaining Contractual Term
Weighted Average Remaining Contractual Life (in years), Exercisable
Income Statement [Abstract]
Share-Based Payment Arrangement [Policy Text Block]
Stock-Based Compensation
Sale of stock, number of shares issued in transaction
Sale of Stock, Number of Shares Issued in Transaction
Issuance of common stock (in shares)
Stock issued during period, shares, new issues (in shares)
Equity issuance costs (in shares)
Lease, Cost [Abstract]
Authorized Shares
Number of authorized to issue shares of convertible preferred stock
Convertible preferred stock, shares authorized (in shares)
Business Combination [Abstract]
Earnings Per Share, Diluted
Earnings Per Share, Diluted, Total
Net (loss) income per share, diluted
Net loss per share of Common Stock - diluted (in dollars per share)
Schedule of Segment Reporting Information, by Segment [Table Text Block]
Schedule of Reconciles Segment Direct Profit or Loss
Merger Agreement And Recapitalization [Abstract]
Merger agreement and recapitalization.
Percent
Effective Income Tax Rate Reconciliation, Percent [Abstract]
us-gaap_IncreaseDecreaseInAccountsPayableTrade
Account payable
ConvertiblePreferredStockCommonStockOwnershipLimitPercent
Percentage of common stock ownership limit of convertible preferred stock
Convertible preferred stock, common stock ownership limit, percent
City Area Code
Payments for Rent
Payments for Rent
Auditor Name
Income Tax Examination, Penalties and Interest Expense
Income Tax Examination, Penalties and Interest Expense, Total
Interest and penalty exposure
Debt Instrument, Face Amount
Aggregate principal amount
Business Combination [Line Items]
Reverse Merger
Deferred Tax Assets, Tax Credit Carryforwards
Deferred Tax Assets, Tax Credit Carryforwards, Total
Orphan drug credit
Counterparty Name [Domain]
Variable lease cost
Variable lease costs
Convertible Note Issuance Seven [Member]
Convertible note issuance seven.
Note 7
Operating Lease, Weighted Average Remaining Lease Term
Weighted average remaining lease term (years)
Segment Reporting Information [Line Items]
Lease Expiration Date
Lease expiration date
Fair Value, Net Derivative Asset (Liability) Measured on Recurring Basis, Unobservable Input Reconciliation [Line Items]
Convertible Note Issuance Twelve [Member]
Convertible note issuance twelve.
Note 12
Cash and Cash Equivalents, Policy [Policy Text Block]
Cash and Cash Equivalents
Derivative Liability, Current
Derivative liabilities - contingent value right liability
Reverse Merger, Conversion Ratio
Reverse merger, conversion ratio.
Reverse merger, conversion ratio (in shares)
Cash and cash equivalents at end of period
us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsIncludingDisposalGroupAndDiscontinuedOperations
Cash and cash equivalents at beginning of period
us-gaap_OperatingIncomeLoss
Operating loss
Loss from operations
Schedule of Weighted Average Remaining Lease Life and Weighted Average Discount Rate [Table Text Block]
Schedule of weighted average remaining lease life and weighted average discount rate.
Schedule of Weighted Average Remaining Lease Life And Weighted Average Discount Rate
Retained Earnings [Member]
Accumulated Deficit [Member]
Conversion of prefunded warrants into common stock (in shares)
Stock Issued During Period, shares, Conversion of prefunded warrants
Stock Issued During Period, shares, Conversion of prefunded warrants.
Convertible Note Issuance Six [Member]
Convertible note issuance six.
Note 6
us-gaap_ShareBasedCompensation
Stock-based compensation
Payments of Stock Issuance Costs
Deferred equity issuance costs
German Research and Development Tax Credit Receivable
German Research and Development Tax Credit Receivable [Policy Text Block]
German research and development tax credit receivable.
Convertible Note Issuance Sixteen [Member]
Convertible note issuance sixteen.
Note 16
Liabilities, Noncurrent
Liabilities, Noncurrent, Total
Long-term liability
Operating Lease, Weighted Average Discount Rate, Percent
Weighted average discount rate
Operating Lease, Liability, Noncurrent
Long-term portion of lease liability
Long-term portion of operating lease liability
Fair Value, Inputs, Level 1 [Member]
Level 1 [Member]
us-gaap_DisclosureTextBlockAbstract
Notes to Financial Statements
us-gaap_NetCashProvidedByUsedInFinancingActivities
Net cash (used in) provided by financing activities
Short-Term Debt [Line Items]
One-time Payment Amount Agreed to Fund Development
One-time payment amount agreed to fund development.
One-time payment amount agreed to fund development
Lease, Cost [Table Text Block]
Schedule of Components of Lease Cost
Change in Accounting Principle, Accounting Standards Update, Adopted [true false]
Auditor Location
Other income (expense)
Other (expense) income:
Derivative Liability, Noncurrent
Derivative liabilities - royalty agreement
Maximum payments to receive upon achievement of milestones
Maximum Payments to Receive upon Achievement of Milestones
Maximum payments to receive upon achievement of milestones.
Derivative Contract [Domain]
Change in Fair Value of Derivative Liabilities - Contingent Value Right Liability
Change in fair value of derivative liabilities - contingent value right liability
Change in fair value of derivative liabilities - contingent value right liability
Business Combination, Recognized Asset Acquired, Receivable, Current
Accounts receivable
Schedule of Potentially Dilutive Securities Excluded from Calculation of Weighted-Average Shares of Common Stock Outstanding
Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table Text Block]
Costs to issue convertible notes
Costs To Issue Convertible Notes
Costs to issue convertible notes.
Income Tax Authority [Domain]
Entity Interactive Data Current
Stockholder's Equity [Line Items]
Stockholder's Equity
Statement of Income Location, Balance [Domain]
Agreement Effective Interest Rate
Agreement effective interest rate.
Agreement effective interest rate
Operating activities:
Cash flows from operating activities
Conversion of preferred stock
Convertible preferred stock, shares issued upon conversion (in shares)
Conversion of preferred stock into common stock (in shares)
Agreement Termination Notice Period
Agreement termination notice period.
Agreement termination notice period
Other Income Expense from Research and Development Tax Credit Receivable
Other income (expense) from research and development tax credit receivable.
Other income - German R&D tax credit receivable
Noncash Interest Expense (Income) Royalty Agreement
Non-cash interest expense (income) royalty agreement.
Non-cash interest expense - royalty agreement
Entity Tax Identification Number
Long-Term Debt, Type [Axis]
Income Tax Authority, Name [Domain]
Palvella [Member]
Palvella.
Palvella [Member]
Effect of Exchange Rate on Cash, Cash Equivalent, Restricted Cash, and Restricted Cash Equivalent, Continuing Operation
Effect of exchange rate change on cash and cash equivalents
Proceeds from Issuance or Sale of Equity
Proceeds from Issuance or Sale of Equity, Total
Proceeds from issuance or sale of equity
Local Phone Number
Thereafter
Lessee Operating Lease Liability Payments Due After Year Four
Lessee operating lease liability payments due after year four.
Proceeds From Amendment To Royalty Agreement
Proceeds from amendment to royalty agreement.
Proceeds from amendement to royalty agreement
Other
Other Liabilities, Current
Share-Based Payment Arrangement, Nonvested Award, Option, Cost Not yet Recognized, Amount
Unrecognized compensation cost
Short-Term Lease, Cost
Short-term lease cost
Denominator:
Weighted Average Number of Shares Outstanding, Diluted [Abstract]
Auditor Opinion [Text Block]
Auditor Opinion
Contingent value rights agreement amount paid.
Contingent value rights agreement amount paid
Adjustments to Additional Paid in Capital, Stock Issued, Issuance Costs
Equity issuance costs
Equity issuance costs
Accounting Policies [Abstract]
Issuance of common stock and prefunded warrants in connection with PIPE
Issuance of common stock and prefunded warrants in connection with PIPE
Issuance of common stock and prefunded warrants in connection with PIPE
Lessee, Operating Lease, Liability, to be Paid, Year Four
2029
Class of Stock [Domain]
Share-Based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Period for Recognition
Expected to be recognized over a remaining weighted-average service period
Accrued Professional Fees, Current
Professional fees
Entity Emerging Growth Company
Tax Credit Carryforward, Name [Domain]