Income Taxes - Schedule of Deferred Tax Assets (Details) - USD ($) $ in Thousands |
12 Months Ended | |
|---|---|---|
Dec. 31, 2025 |
Dec. 31, 2024 |
|
| Income Tax Disclosure [Abstract] | ||
| Royalty agreement liabilities | $ 5,415 | $ 3,913 |
| Net operating loss | 91,962 | 81,971 |
| Section 174 R&D capitalization | 5,797 | 6,288 |
| Stock-based compensation | 1,791 | 419 |
| Accrued expenses and other | 690 | 744 |
| Other tax credits | 589 | 24 |
| Orphan drug credit | 199 | 199 |
| Lease liabilities | 158 | 0 |
| Startup costs | 76 | 86 |
| Deferred tax assets before valuation allowance | 106,677 | 93,644 |
| Right of use assets | (142) | 0 |
| Other deferred tax liabilities | (400) | (390) |
| Net deferred tax | 106,135 | 93,254 |
| Valuation allowance | (106,135) | (93,254) |
| Net deferred tax assets | 0 | 0 |
| (Increase) decrease in valuation allowance | $ (12,881) | $ (77,240) |
| X | ||||||||||
- Definition Amount before allocation of valuation allowances of deferred tax asset attributable to deductible temporary differences from lease liability No definition available.
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| X | ||||||||||
- Definition Amount before allocation of valuation allowances of deferred tax asset attributable to deductible temporary differences from accrued compensation and other costs No definition available.
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| X | ||||||||||
- Definition Amount before allocation of valuation allowances of deferred tax asset attributable to capitalized research and development. No definition available.
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| X | ||||||||||
- Definition Deferred tax assets, royalty agreement liabilities. No definition available.
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| X | ||||||||||
- Definition Deferred tax assets, startup costs. No definition available.
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| X | ||||||||||
- Definition Deferred tax liabilities, right of use assets No definition available.
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| X | ||||||||||
- Definition Amount before allocation of valuation allowances of deferred tax asset attributable to deductible temporary differences and carryforwards. Reference 1: http://www.xbrl.org/2003/role/disclosureRef
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| X | ||||||||||
- Definition Amount, after allocation of valuation allowances and deferred tax liability, of deferred tax asset attributable to deductible differences and carryforwards, without jurisdictional netting. Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef
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| X | ||||||||||
- Definition Amount after allocation of valuation allowances of deferred tax asset attributable to deductible temporary differences and carryforwards. Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef
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| X | ||||||||||
- Definition Amount before allocation of valuation allowances of deferred tax asset attributable to deductible operating loss carryforwards. Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef
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| X | ||||||||||
- Definition Amount, before allocation of a valuation allowances, of deferred tax assets attributable to deductible tax credit carryforwards including, but not limited to, research, foreign, general business, alternative minimum tax, and other deductible tax credit carryforwards. Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef
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| X | ||||||||||
- Definition Amount, before allocation of valuation allowance, of deferred tax asset attributable to deductible tax credit carryforwards, classified as other. Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef
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| X | ||||||||||
- Definition Amount before allocation of valuation allowances of deferred tax asset attributable to deductible temporary differences from share-based compensation. Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef
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| X | ||||||||||
- Definition Amount of deferred tax assets for which it is more likely than not that a tax benefit will not be realized. Reference 1: http://www.xbrl.org/2003/role/disclosureRef
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| X | ||||||||||
- Definition Amount of deferred tax liability attributable to taxable temporary differences classified as other. Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef
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| X | ||||||||||
- References No definition available.
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| X | ||||||||||
- Definition Amount of increase (decrease) in the valuation allowance for a specified deferred tax asset. Reference 1: http://www.xbrl.org/2003/role/disclosureRef
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