Income Taxes - Additional Information (Details) - USD ($)	12 Months Ended
Dec. 31, 2025	Dec. 31, 2024
Income Taxes [Line Items]
Current income tax expense (benefit)	$ 0	$ 0
Valuation allowance	106,135,000	93,254,000
Unrecognized tax benefits	0	0
Interest and penalty exposure	0	$ 0
Orphan drug credits	$ 200,000
Domestic Tax Authority [Member]
Income Taxes [Line Items]
Income tax examination year	2019 2020 2021 2022 2023 2024 2025
Operating loss carryforwards	$ 129,400,000
Domestic Tax Authority [Member] \| Internal Revenue Service (IRS) [Member]
Income Taxes [Line Items]
Open Tax Year	2019 2020 2021 2022 2023 2024 2025
State and Local Jurisdiction [Member]
Income Taxes [Line Items]
Operating loss carryforwards	$ 113,300,000
Foreign Tax Authority [Member]
Income Taxes [Line Items]
Tax loss carryforwards	$ 1,200,000
Percentage of taxable income and trade profit	60.00%
Foreign Tax Authority [Member] \| Corporate Income Tax [Member]
Income Taxes [Line Items]
Operating loss carryforwards	$ 219,400,000
Foreign Tax Authority [Member] \| Trade Tax [Member]
Income Taxes [Line Items]
Operating loss carryforwards	$ 215,100,000

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Operating loss carry forwards orphan drug tax credit carry forward.

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Tax loss carryforwards.

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Amount of current income tax expense (benefit) pertaining to taxable income (loss) from continuing operations.

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Amount of deferred tax assets for which it is more likely than not that a tax benefit will not be realized.

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The sum of the amounts of estimated penalties and interest recognized in the period arising from income tax examinations.

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Tax year being audited in the income tax examination, in YYYY format.

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Tax year that remains open to examination under enacted tax laws, in YYYY format.

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Amount of operating loss carryforward, before tax effects, available to reduce future taxable income under enacted tax laws.

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Amount of unrecognized tax benefits.

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