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  <xsd:element name="LongTermIncentiveProgramPercentageOfOutstandingShares" id="fbio_LongTermIncentiveProgramPercentageOfOutstandingShares" type="dtr-types:percentItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" />
  <xsd:element name="TgtxMember" id="fbio_TgtxMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" abstract="true" nillable="true" xbrli:periodType="duration" />
  <xsd:element name="OtherDebtMember" id="fbio_OtherDebtMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" abstract="true" nillable="true" xbrli:periodType="duration" />
  <xsd:element name="IdbNotePayableMember" id="fbio_IdbNotePayableMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" abstract="true" nillable="true" xbrli:periodType="duration" />
  <xsd:element name="LesseeLeasePortfolioAndOtherSupplementalLeaseInformation" id="fbio_LesseeLeasePortfolioAndOtherSupplementalLeaseInformation" type="dtr-types:textBlockItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" />
  <xsd:element name="TwoThousandSeventeenLongTermIncentivePlanMember" id="fbio_TwoThousandSeventeenLongTermIncentivePlanMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" abstract="true" nillable="true" xbrli:periodType="duration" />
  <xsd:element name="TwoThousandSixteenLongTermIncentivePlanMember" id="fbio_TwoThousandSixteenLongTermIncentivePlanMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" abstract="true" nillable="true" xbrli:periodType="duration" />
  <xsd:element name="TwoThousandFifteenLongTermIncentivePlanMember" id="fbio_TwoThousandFifteenLongTermIncentivePlanMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" abstract="true" nillable="true" xbrli:periodType="duration" />
  <xsd:element name="OtherPartnersMember" id="fbio_OtherPartnersMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" abstract="true" nillable="true" xbrli:periodType="duration" />
  <xsd:element name="ResearchAndDevelopmentLicensesAcquiredExpense" id="fbio_ResearchAndDevelopmentLicensesAcquiredExpense" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:balance="debit" xbrli:periodType="duration" />
  <xsd:element name="IntangibleAssetsNotYetPlacedInService" id="fbio_IntangibleAssetsNotYetPlacedInService" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:balance="debit" xbrli:periodType="instant" />
  <xsd:element name="DebtPrepaymentPenalties" id="fbio_DebtPrepaymentPenalties" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:balance="debit" xbrli:periodType="duration" />
  <xsd:element name="PaidInKindDividendAsPercentageOfFullyDilutedOutstandingCapitalization" id="fbio_PaidInKindDividendAsPercentageOfFullyDilutedOutstandingCapitalization" type="dtr-types:percentItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" />
  <xsd:element name="AnnualEquityFeeAsPercentageOfFullyDilutedOutstandingCapitalization" id="fbio_AnnualEquityFeeAsPercentageOfFullyDilutedOutstandingCapitalization" type="dtr-types:percentItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" />
  <xsd:element name="ManagementServicesAgreementsMember" id="fbio_ManagementServicesAgreementsMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" abstract="true" nillable="true" xbrli:periodType="duration" />
  <xsd:element name="AnnualManagementServicesAgreementFeeIncome" id="fbio_AnnualManagementServicesAgreementFeeIncome" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:balance="credit" xbrli:periodType="duration" />
  <xsd:element name="AnnualManagementServicesAgreementFeeExpense" id="fbio_AnnualManagementServicesAgreementFeeExpense" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:balance="debit" xbrli:periodType="duration" />
  <xsd:element name="MinimumOwnershipInterestInSubsidiariesForConsolidatedIncomeTaxReturn" id="fbio_MinimumOwnershipInterestInSubsidiariesForConsolidatedIncomeTaxReturn" type="dtr-types:percentItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" />
  <xsd:element name="CustomerTwoMember" id="fbio_CustomerTwoMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" abstract="true" nillable="true" xbrli:periodType="duration" />
  <xsd:element name="IssuanceOfCommonStockUnderPartnerCompanysEmployeeStockPurchaseProgram" id="fbio_IssuanceOfCommonStockUnderPartnerCompanysEmployeeStockPurchaseProgram" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:balance="credit" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsGrantsInPeriodFairValue" id="fbio_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsGrantsInPeriodFairValue" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:balance="credit" xbrli:periodType="duration" />
  <xsd:element name="DeferredTaxAssetsReserveOnSalesReturnDiscountAndBadDebt" id="fbio_DeferredTaxAssetsReserveOnSalesReturnDiscountAndBadDebt" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:balance="debit" xbrli:periodType="instant" />
  <xsd:element name="OperatingLossCarryforwardsWithoutExpiration" id="fbio_OperatingLossCarryforwardsWithoutExpiration" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:balance="debit" xbrli:periodType="instant" />
  <xsd:element name="AccutaneMember" id="fbio_AccutaneMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" abstract="true" nillable="true" xbrli:periodType="duration" />
  <xsd:element name="PercentageOfMarketPriceOfCommonStockForAdditionalWarrants" id="fbio_PercentageOfMarketPriceOfCommonStockForAdditionalWarrants" type="dtr-types:percentItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" />
  <xsd:element name="OwnershipPercentageOfSubsidiaryToConsolidateTheirAccounts" id="fbio_OwnershipPercentageOfSubsidiaryToConsolidateTheirAccounts" type="dtr-types:percentItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" />
  <xsd:element name="MaintainsVotingControlMember" id="fbio_MaintainsVotingControlMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" abstract="true" nillable="true" xbrli:periodType="duration" />
  <xsd:element name="CollaborationRevenue" id="fbio_CollaborationRevenue" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:balance="credit" xbrli:periodType="duration" />
  <xsd:element name="NumberOfSharesIssuableForAtMarketOffering" id="fbio_NumberOfSharesIssuableForAtMarketOffering" type="xbrli:sharesItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" />
  <xsd:element name="PartnerCompanyConvertiblePreferredSharesMember" id="fbio_PartnerCompanyConvertiblePreferredSharesMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" abstract="true" nillable="true" xbrli:periodType="duration" />
  <xsd:element name="PartnerCompanyInstallmentPaymentsLicensesCurrent" id="fbio_PartnerCompanyInstallmentPaymentsLicensesCurrent" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:balance="credit" xbrli:periodType="instant" />
  <xsd:element name="PlacementAgentWarrantsMember" id="fbio_PlacementAgentWarrantsMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" abstract="true" nillable="true" xbrli:periodType="duration" />
  <xsd:element name="QbrexzaMember" id="fbio_QbrexzaMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" abstract="true" nillable="true" xbrli:periodType="duration" />
  <xsd:element name="AccruedReturnReserveCurrent" id="fbio_AccruedReturnReserveCurrent" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:balance="credit" xbrli:periodType="instant" />
  <xsd:element name="AccretionOfPartnerCompanyConvertiblePreferredShares" id="fbio_AccretionOfPartnerCompanyConvertiblePreferredShares" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:balance="debit" xbrli:periodType="duration" />
  <xsd:element name="NumberOfCustomers" id="fbio_NumberOfCustomers" type="xbrli:integerItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" />
  <xsd:element name="NumberOfPartnerCompaniesThatHaveConsummatedStrategicPartnershipsWithIndustryLeaders" id="fbio_NumberOfPartnerCompaniesThatHaveConsummatedStrategicPartnershipsWithIndustryLeaders" type="xbrli:integerItemType" substitutionGroup="xbrli:item" abstract="false" nillable="true" xbrli:periodType="duration" />
  <xsd:element name="NumberOfPartnerCompaniesThatArePubliclyTraded" id="fbio_NumberOfPartnerCompaniesThatArePubliclyTraded" type="xbrli:integerItemType" substitutionGroup="xbrli:item" abstract="false" nillable="true" xbrli:periodType="duration" />
  <xsd:element name="Ur1TherapeuticsIncMember" id="fbio_Ur1TherapeuticsIncMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" abstract="true" nillable="true" xbrli:periodType="duration" />
  <xsd:element name="SaleOfStockPercentageOfSharesIssuedInTransaction" id="fbio_SaleOfStockPercentageOfSharesIssuedInTransaction" type="dtr-types:percentItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="LicenseAgreementsMember" id="fbio_LicenseAgreementsMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="LicenseAgreementsUpfrontAndMilestonePayments" id="fbio_LicenseAgreementsUpfrontAndMilestonePayments" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" xbrli:balance="credit" />
  <xsd:element name="LicenseAgreementsSaleBasedMilestonePayments" id="fbio_LicenseAgreementsSaleBasedMilestonePayments" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" xbrli:balance="credit" />
  <xsd:element name="VyneProductAcquisitionMember" id="fbio_VyneProductAcquisitionMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="AssetAcquisitionFuturePaymentsDue" id="fbio_AssetAcquisitionFuturePaymentsDue" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" xbrli:balance="credit" />
  <xsd:element name="AnnualSalesOfOneHundredMillionMember" id="fbio_AnnualSalesOfOneHundredMillionMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="AnnualSalesOfTwoHundredMillionMember" id="fbio_AnnualSalesOfTwoHundredMillionMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="AnnualSalesOfThreeHundredMillionMember" id="fbio_AnnualSalesOfThreeHundredMillionMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="AnnualSalesOfFourHundredMillionMember" id="fbio_AnnualSalesOfFourHundredMillionMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="AnnualSalesOfFiveHundredMillionMember" id="fbio_AnnualSalesOfFiveHundredMillionMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="EmployeeAndNonemployeeAwardsMember" id="fbio_EmployeeAndNonemployeeAwardsMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="PartnerCompanyNotesPayableMember" id="fbio_PartnerCompanyNotesPayableMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="SeriesWarrantsMember" id="fbio_SeriesWarrantsMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="SeriesBWarrantsMember" id="fbio_SeriesBWarrantsMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="WarrantLiabilitiesCurrent" id="fbio_WarrantLiabilitiesCurrent" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" xbrli:balance="credit" />
  <xsd:element name="ProceedsFromPartnerCompaniesSaleOfStockAndWarrantsNet" id="fbio_ProceedsFromPartnerCompaniesSaleOfStockAndWarrantsNet" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="debit" />
  <xsd:element name="StockRepurchaseProgramContingentFeePayableOnProceedsOfFutureFinancingsPercent" id="fbio_StockRepurchaseProgramContingentFeePayableOnProceedsOfFutureFinancingsPercent" type="dtr-types:percentItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" />
  <xsd:element name="StockRepurchaseProgramContingentFeePayableOnProceedsOfFutureFinancingsAmount" id="fbio_StockRepurchaseProgramContingentFeePayableOnProceedsOfFutureFinancingsAmount" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" xbrli:balance="credit" />
  <xsd:element name="ConvertibleClassBPreferredStockMember" id="fbio_ConvertibleClassBPreferredStockMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="WarrantsFairValueDisclosure" id="fbio_WarrantsFairValueDisclosure" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" xbrli:balance="credit" />
  <xsd:element name="CommonStockWarrantsMember" id="fbio_CommonStockWarrantsMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="ScheduleOfRevaluationOfWarrantLiabilityTableTextBloc" id="fbio_ScheduleOfRevaluationOfWarrantLiabilityTableTextBloc" type="dtr-types:textBlockItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="DirectOfferingMember" id="fbio_DirectOfferingMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="PreFundedWarrantsMember" id="fbio_PreFundedWarrantsMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="WarrantsIssuedNumber" id="fbio_WarrantsIssuedNumber" type="xbrli:sharesItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="UnitPricePerShare" id="fbio_UnitPricePerShare" type="dtr-types:perShareItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" />
  <xsd:element name="AvenueTherapeuticsIncMember" id="fbio_AvenueTherapeuticsIncMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="PartnerCompanyEquityOffering" id="fbio_PartnerCompanyEquityOffering" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="credit" />
  <xsd:element name="ProceedsFromIssuanceOfCommonStockExcludingAtMarketOfferings" id="fbio_ProceedsFromIssuanceOfCommonStockExcludingAtMarketOfferings" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="debit" />
  <xsd:element name="ProceedsFromIssuanceOfCommonStockFromEmployeeStockPurchasePlan" id="fbio_ProceedsFromIssuanceOfCommonStockFromEmployeeStockPurchasePlan" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="debit" />
  <xsd:element name="ConcurrentPrivatePlacementMember" id="fbio_ConcurrentPrivatePlacementMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="PartnerCompanyExerciseOfOptionsForCash" id="fbio_PartnerCompanyExerciseOfOptionsForCash" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="credit" />
  <xsd:element name="PaymentOfOaktreeNote" id="fbio_PaymentOfOaktreeNote" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="credit" />
  <xsd:element name="CommonSharesIssuedForDividendOnPartnerCompanySConvertiblePreferredShares" id="fbio_CommonSharesIssuedForDividendOnPartnerCompanySConvertiblePreferredShares" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="credit" />
  <xsd:element name="CommonSharesIssuedForDividendOnPartnerCompanySConvertiblePreferredSharesInShares" id="fbio_CommonSharesIssuedForDividendOnPartnerCompanySConvertiblePreferredSharesInShares" type="xbrli:sharesItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="UbrigeneBostonBiosciencesInc.Member" id="fbio_UbrigeneBostonBiosciencesInc.Member" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="WarrantsIssued1" id="fbio_WarrantsIssued1" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="credit" />
  <xsd:element name="AnnualCashDividendPerSharePayable" id="fbio_AnnualCashDividendPerSharePayable" type="dtr-types:perShareItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" />
  <xsd:element name="MonthlyCashDividendPerSharePayable" id="fbio_MonthlyCashDividendPerSharePayable" type="dtr-types:perShareItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" />
  <xsd:element name="LicensesAgreementsAbstract" id="fbio_LicensesAgreementsAbstract" type="xbrli:stringItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="OwnershipRatioOfPreferredStockAndCommonStock" id="fbio_OwnershipRatioOfPreferredStockAndCommonStock" type="xbrli:pureItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" />
  <xsd:element name="January2023WarrantsMember" id="fbio_January2023WarrantsMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="RegisteredOfferingMember" id="fbio_RegisteredOfferingMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="UnregisteredWarrantsMember" id="fbio_UnregisteredWarrantsMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="SentynlDevelopmentAndAssetPurchaseAgreementMember" id="fbio_SentynlDevelopmentAndAssetPurchaseAgreementMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="AnnualNetSalesUpTo75MillionMember" id="fbio_AnnualNetSalesUpTo75MillionMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="AnnualNetSalesBetween75MillionAnd100MillionMember" id="fbio_AnnualNetSalesBetween75MillionAnd100MillionMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="AnnualNetSalesInExcessOf100MillionMember" id="fbio_AnnualNetSalesInExcessOf100MillionMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="WarrantChargeInConjunctionWithOaktreeDebt" id="fbio_WarrantChargeInConjunctionWithOaktreeDebt" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="credit" />
  <xsd:element name="SwkTermLoanMember" id="fbio_SwkTermLoanMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="ExerciseOfCommonStockWarrants" id="fbio_ExerciseOfCommonStockWarrants" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="debit" />
  <xsd:element name="StockIssuedDuringPeriodValueWarrantsExercised" id="fbio_StockIssuedDuringPeriodValueWarrantsExercised" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="credit" />
  <xsd:element name="StockIssuedDuringPeriodSharesWarrantsExercised" id="fbio_StockIssuedDuringPeriodSharesWarrantsExercised" type="xbrli:sharesItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="DebtInstrumentFloorRate" id="fbio_DebtInstrumentFloorRate" type="xbrli:pureItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" />
  <xsd:element name="DebtInstrumentPeriodicPaymentPercentageOfPrincipalAmount" id="fbio_DebtInstrumentPeriodicPaymentPercentageOfPrincipalAmount" type="dtr-types:percentItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="DebtInstrumentThresholdRevenueConsideredForNoPeriodicPayment" id="fbio_DebtInstrumentThresholdRevenueConsideredForNoPeriodicPayment" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="credit" />
  <xsd:element name="DebtInstrumentPercentageOfExitFees" id="fbio_DebtInstrumentPercentageOfExitFees" type="dtr-types:percentItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" />
  <xsd:element name="ClassOfWarrantOrRightNumberOfSharesExercised" id="fbio_ClassOfWarrantOrRightNumberOfSharesExercised" type="xbrli:sharesItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="ClassOfWarrantOrRightExercisedWeightedAverageExercisePrice" id="fbio_ClassOfWarrantOrRightExercisedWeightedAverageExercisePrice" type="dtr-types:perShareItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="November2023WarrantsMember" id="fbio_November2023WarrantsMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="ClassOfWarrantOrRightExercisePriceOfWarrantsOrRightsAgreedByInvestor" id="fbio_ClassOfWarrantOrRightExercisePriceOfWarrantsOrRightsAgreedByInvestor" type="dtr-types:perShareItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" />
  <xsd:element name="DeferredTaxAssetsSection174ResearchAndDevelopmentExpenditureCapitalization" id="fbio_DeferredTaxAssetsSection174ResearchAndDevelopmentExpenditureCapitalization" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" xbrli:balance="debit" />
  <xsd:element name="ProvisionToReturn" id="fbio_ProvisionToReturn" type="dtr-types:percentItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="AdjustmentForWarrants" id="fbio_AdjustmentForWarrants" type="dtr-types:percentItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="CashAndCashEquivalentsParentCompany" id="fbio_CashAndCashEquivalentsParentCompany" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" xbrli:balance="debit" />
  <xsd:element name="SeriesTwoWarrantsMember" id="fbio_SeriesTwoWarrantsMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="SeriesOneWarrantsMember" id="fbio_SeriesOneWarrantsMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="SeriesThreeWarrantsMember" id="fbio_SeriesThreeWarrantsMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="OtherLegacyProductRevenueMember" id="fbio_OtherLegacyProductRevenueMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="EffectOfSeriesPreferredDividendsOnNetLossPerShareCalculation" id="fbio_EffectOfSeriesPreferredDividendsOnNetLossPerShareCalculation" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="debit" />
  <xsd:element name="CommonSharesIssuedForExchangeOfPartnerCompanySConvertiblePreferredShares" id="fbio_CommonSharesIssuedForExchangeOfPartnerCompanySConvertiblePreferredShares" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="credit" />
  <xsd:element name="CommonSharesIssuedForExchangeOfPartnerCompanySConvertiblePreferredSharesInShares" id="fbio_CommonSharesIssuedForExchangeOfPartnerCompanySConvertiblePreferredSharesInShares" type="xbrli:sharesItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="WarrantsIssuedInConjunctionWithExchangeOfPartnerCompanySConvertiblePreferredShares" id="fbio_WarrantsIssuedInConjunctionWithExchangeOfPartnerCompanySConvertiblePreferredShares" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="credit" />
  <xsd:element name="AdjustmentsToAdditionalPaidInCapitalExerciseOfPartnerCompanyOptionsAndWarrants" id="fbio_AdjustmentsToAdditionalPaidInCapitalExerciseOfPartnerCompanyOptionsAndWarrants" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="credit" />
  <xsd:element name="ShelfRegistration2024StatementMember" id="fbio_ShelfRegistration2024StatementMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="NumberOfDaysToDisposeOfAssetsPurchased" id="fbio_NumberOfDaysToDisposeOfAssetsPurchased" type="xbrli:durationItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="AssetAcquisitionConsiderationSubsequentPaymentExtendedDuePeriod" id="fbio_AssetAcquisitionConsiderationSubsequentPaymentExtendedDuePeriod" type="xbrli:durationItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="ExchangeOfPartnerCompanyConvertiblePreferredShares" id="fbio_ExchangeOfPartnerCompanyConvertiblePreferredShares" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="credit" />
  <xsd:element name="AssetsHeldForSalePolicyTextBlock" id="fbio_AssetsHeldForSalePolicyTextBlock" type="dtr-types:textBlockItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="DebtInstrumentNumberOfInterestOnlyPeriod" id="fbio_DebtInstrumentNumberOfInterestOnlyPeriod" type="xbrli:durationItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="DebtInstrumentCapRate" id="fbio_DebtInstrumentCapRate" type="xbrli:pureItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" />
  <xsd:element name="DebtInstrumentPercentageOfThenOutstandingPrincipalBalanceDueOnSpecifiedDate" id="fbio_DebtInstrumentPercentageOfThenOutstandingPrincipalBalanceDueOnSpecifiedDate" type="dtr-types:percentItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" />
  <xsd:element name="DebtInstrumentAggregateOfPrincipalPrepaymentAmountMinimum" id="fbio_DebtInstrumentAggregateOfPrincipalPrepaymentAmountMinimum" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="debit" />
  <xsd:element name="DebtInstrumentAggregateOfPrincipalPrepaymentAmountInMultiples" id="fbio_DebtInstrumentAggregateOfPrincipalPrepaymentAmountInMultiples" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="debit" />
  <xsd:element name="DebtInstrumentMandatoryPrepaymentExcessProceedsFromAnyOfCompanySSubsidiariesOtherThanInConnectionWithCertainMonetizationEvents" id="fbio_DebtInstrumentMandatoryPrepaymentExcessProceedsFromAnyOfCompanySSubsidiariesOtherThanInConnectionWithCertainMonetizationEvents" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="credit" />
  <xsd:element name="MinimumLiquidityToBeMaintained" id="fbio_MinimumLiquidityToBeMaintained" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" xbrli:balance="debit" />
  <xsd:element name="MinimumNetSalesToBeMaintained" id="fbio_MinimumNetSalesToBeMaintained" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="credit" />
  <xsd:element name="DebtInstrumentThresholdAmountOfAggregateCommonEquityOrCashDistributionsToBeReceived" id="fbio_DebtInstrumentThresholdAmountOfAggregateCommonEquityOrCashDistributionsToBeReceived" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="debit" />
  <xsd:element name="DebtInstrumentAggregateCommonEquityOrCashDistributionsToBeReceivedAsPercentageOfAmountSetForthInAnnualBudget" id="fbio_DebtInstrumentAggregateCommonEquityOrCashDistributionsToBeReceivedAsPercentageOfAmountSetForthInAnnualBudget" type="dtr-types:percentItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="DebtInstrumentThresholdAmountOfOutstandingPrincipalForApplicabilityOfCovenants" id="fbio_DebtInstrumentThresholdAmountOfOutstandingPrincipalForApplicabilityOfCovenants" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" xbrli:balance="credit" />
  <xsd:element name="PreferredStockMonthlyDividendsPerSharePaused" id="fbio_PreferredStockMonthlyDividendsPerSharePaused" type="dtr-types:perShareItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="DeferredDividends" id="fbio_DeferredDividends" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" xbrli:balance="credit" />
  <xsd:element name="AssetAcquisitionPercentageOfCommonStockIssued" id="fbio_AssetAcquisitionPercentageOfCommonStockIssued" type="dtr-types:percentItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="ThresholdPercentageOfFullyDilutedEquityCapitalizationPosition" id="fbio_ThresholdPercentageOfFullyDilutedEquityCapitalizationPosition" type="dtr-types:percentItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" />
  <xsd:element name="MaximumAmountOfEquitySecuritiesToBeRaised" id="fbio_MaximumAmountOfEquitySecuritiesToBeRaised" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" xbrli:balance="credit" />
  <xsd:element name="CrystalysTherapeuticsIncMember" id="fbio_CrystalysTherapeuticsIncMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="PercentageOfRoyaltyOnFutureNetSales" id="fbio_PercentageOfRoyaltyOnFutureNetSales" type="dtr-types:percentItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="ProceedsFromStockAndWarrantsIssuedForExchangeOfPartnerCompanyPreferredShares" id="fbio_ProceedsFromStockAndWarrantsIssuedForExchangeOfPartnerCompanyPreferredShares" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="debit" />
  <xsd:element name="AdjustmentsToAdditionalPaidInCapitalDividendsInExcessOfCommonStock" id="fbio_AdjustmentsToAdditionalPaidInCapitalDividendsInExcessOfCommonStock" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="debit" />
  <xsd:element name="StockIssuedDuringPeriodSharesCommonSharesForDirectOfferingInShares" id="fbio_StockIssuedDuringPeriodSharesCommonSharesForDirectOfferingInShares" type="xbrli:sharesItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="GainLossOnCommonStockWarrantLiabilities" id="fbio_GainLossOnCommonStockWarrantLiabilities" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="credit" />
  <xsd:element name="InterestExpenseTotalNet" id="fbio_InterestExpenseTotalNet" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="debit" />
  <xsd:element name="FairValueOfAssetsReceivedByPartnerCompanyInRepurchaseTransaction" id="fbio_FairValueOfAssetsReceivedByPartnerCompanyInRepurchaseTransaction" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="credit" />
  <xsd:element name="FairValueOfSuppliesReceivedByPartnerCompanyExpensedToResearchAndDevelopment" id="fbio_FairValueOfSuppliesReceivedByPartnerCompanyExpensedToResearchAndDevelopment" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="credit" />
  <xsd:element name="PartnerCompanyAccountsReceivableWriteOffRelatedToRepurchaseTransaction" id="fbio_PartnerCompanyAccountsReceivableWriteOffRelatedToRepurchaseTransaction" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="debit" />
  <xsd:element name="PartnerCompanyAccountsPayableWriteOffRelatedToRepurchaseTransaction" id="fbio_PartnerCompanyAccountsPayableWriteOffRelatedToRepurchaseTransaction" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="credit" />
  <xsd:element name="PartnerCompanySNetPurchaseConsiderationOfAssetsRecordedToAccruedOther" id="fbio_PartnerCompanySNetPurchaseConsiderationOfAssetsRecordedToAccruedOther" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="debit" />
  <xsd:element name="AssetAcquisitionConsiderationTransferredInExcessOfFairValueOfAssetsAllocatedToSupplies" id="fbio_AssetAcquisitionConsiderationTransferredInExcessOfFairValueOfAssetsAllocatedToSupplies" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="debit" />
  <xsd:element name="PropertyPlantAndEquipmentAccumulatedImpairment" id="fbio_PropertyPlantAndEquipmentAccumulatedImpairment" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" xbrli:balance="credit" />
  <xsd:element name="PerShareAmountReducedFromSharePriceToCalculateWarrantPrice" id="fbio_PerShareAmountReducedFromSharePriceToCalculateWarrantPrice" type="dtr-types:perShareItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" />
  <xsd:element name="MinimumNetSaleTrailingPeriod" id="fbio_MinimumNetSaleTrailingPeriod" type="xbrli:durationItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="IfOutstandingPrincipalBalanceIsLessThanOrEqualTo10MillionMember" id="fbio_IfOutstandingPrincipalBalanceIsLessThanOrEqualTo10MillionMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="IfOutstandingPrincipalBalanceIsBetween10MillionAnd25MillionMember" id="fbio_IfOutstandingPrincipalBalanceIsBetween10MillionAnd25MillionMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="OaktreeNote2Member" id="fbio_OaktreeNote2Member" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="PartnerCompanyContingentCallOptionAccretionMember" id="fbio_PartnerCompanyContingentCallOptionAccretionMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="OaktreeWarrantsMember" id="fbio_OaktreeWarrantsMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="FairValueOfWarrantsAndRightsOutstandingBasedOnValuationInputs" id="fbio_FairValueOfWarrantsAndRightsOutstandingBasedOnValuationInputs" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" xbrli:balance="credit" />
  <xsd:element name="ClassOfWarrantOrRightNumberOfWarrantsIssued" id="fbio_ClassOfWarrantOrRightNumberOfWarrantsIssued" type="xbrli:sharesItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" />
  <xsd:element name="ConcurrentPrivatePlacementWarrantsMember" id="fbio_ConcurrentPrivatePlacementWarrantsMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="PrivatePlacementWarrantsMember" id="fbio_PrivatePlacementWarrantsMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="UnregisteredWarrantsOneMember" id="fbio_UnregisteredWarrantsOneMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="UnregisteredWarrantsTwoMember" id="fbio_UnregisteredWarrantsTwoMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="ThresholdQualifiedFinancingForExpiryOfRepurchaseOption" id="fbio_ThresholdQualifiedFinancingForExpiryOfRepurchaseOption" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" xbrli:balance="credit" />
  <xsd:element name="AssetsSoldUnderAgreementsToRepurchaseAccretionExpense" id="fbio_AssetsSoldUnderAgreementsToRepurchaseAccretionExpense" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="debit" />
  <xsd:element name="LossContingencyReceivableOnRegulatoryApproval" id="fbio_LossContingencyReceivableOnRegulatoryApproval" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" xbrli:balance="debit" />
  <xsd:element name="PercentageOfAmountReleasedFromEscrowFund" id="fbio_PercentageOfAmountReleasedFromEscrowFund" type="dtr-types:percentItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" />
  <xsd:element name="LesseeOperatingLeaseLiabilityToBePaidAfterYearFour" id="fbio_LesseeOperatingLeaseLiabilityToBePaidAfterYearFour" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" xbrli:balance="credit" />
  <xsd:element name="AvenueSubscriptionAndForgivenessAgreementMember" id="fbio_AvenueSubscriptionAndForgivenessAgreementMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="PercentageOfAmountOwedConvertedIntoShares" id="fbio_PercentageOfAmountOwedConvertedIntoShares" type="dtr-types:percentItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" />
  <xsd:element name="PercentageOfForgivenessOnAmountOwed" id="fbio_PercentageOfForgivenessOnAmountOwed" type="dtr-types:percentItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" />
  <xsd:element name="CollaborationrevenueMember" id="fbio_CollaborationrevenueMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="PropertyPlantAndEquipmentHeldForSaleMember" id="fbio_PropertyPlantAndEquipmentHeldForSaleMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="XiminoSettlementMember" id="fbio_XiminoSettlementMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="AssetsAcquisitionNumberOfDaysToAssumeControlOverDevelopmentOfCutx101" id="fbio_AssetsAcquisitionNumberOfDaysToAssumeControlOverDevelopmentOfCutx101" type="xbrli:integerItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="CommonSharesIssuableForDividendOnPartnerCompanyConvertiblePreferredShares" id="fbio_CommonSharesIssuableForDividendOnPartnerCompanyConvertiblePreferredShares" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="debit" />
  <xsd:element name="ProceedsFromIssuanceOfPaymentsForRedemptionsOfPartnerCompanyPreferredStock" id="fbio_ProceedsFromIssuanceOfPaymentsForRedemptionsOfPartnerCompanyPreferredStock" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="credit" />
  <xsd:element name="ProceedsfromexerciseOfPartnerCompaniesOptionsAndWarrantsNet" id="fbio_ProceedsfromexerciseOfPartnerCompaniesOptionsAndWarrantsNet" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="debit" />
  <xsd:element name="AccruedResearchAndDevelopmentExpensePolicyPolicyTextBlock" id="fbio_AccruedResearchAndDevelopmentExpensePolicyPolicyTextBlock" type="dtr-types:textBlockItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="WarrantLiabilityPolicyPolicyTextBlock" id="fbio_WarrantLiabilityPolicyPolicyTextBlock" type="dtr-types:textBlockItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="SunPharmaceuticalIndustriesIncMember" id="fbio_SunPharmaceuticalIndustriesIncMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="IfMilestoneAchievedOnOrBeforeDateThatIs12MonthsPriorToDeadlineDateAndApprovalsForDosingOnceEveryThreeWeeksMember" id="fbio_IfMilestoneAchievedOnOrBeforeDateThatIs12MonthsPriorToDeadlineDateAndApprovalsForDosingOnceEveryThreeWeeksMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="IfMilestoneAchievedOnOrBeforeDateThatIs12MonthsPriorToDeadlineDateAndApprovalsForDosingMoreFrequentThanEveryThreeWeeksMember" id="fbio_IfMilestoneAchievedOnOrBeforeDateThatIs12MonthsPriorToDeadlineDateAndApprovalsForDosingMoreFrequentThanEveryThreeWeeksMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="IfMilestoneAchievedOnOrAfterDateThatIs12MonthsPriorToDeadlineDateAndApprovalsForDosingOnceEveryThreeWeeksMember" id="fbio_IfMilestoneAchievedOnOrAfterDateThatIs12MonthsPriorToDeadlineDateAndApprovalsForDosingOnceEveryThreeWeeksMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="IfMilestoneAchievedOnOrAfterDateThatIs12MonthsPriorToDeadlineDateAndApprovalsForDosingMoreFrequentThanEveryThreeWeeksMember" id="fbio_IfMilestoneAchievedOnOrAfterDateThatIs12MonthsPriorToDeadlineDateAndApprovalsForDosingMoreFrequentThanEveryThreeWeeksMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="MergerAgreementContingentCashConsiderationReceivableForEachOutstandingSharesUponAchievementOfMilestoneCondition" id="fbio_MergerAgreementContingentCashConsiderationReceivableForEachOutstandingSharesUponAchievementOfMilestoneCondition" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" xbrli:balance="debit" />
  <xsd:element name="MergerAgreementMilestoneDeadlineDateDeterminationTerm" id="fbio_MergerAgreementMilestoneDeadlineDateDeterminationTerm" type="xbrli:durationItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="SeriesC1WarrantsMember" id="fbio_SeriesC1WarrantsMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="PartnerCompanyInstallmentPaymentsSettlementAmount" id="fbio_PartnerCompanyInstallmentPaymentsSettlementAmount" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" xbrli:balance="debit" />
  <xsd:element name="PartnerCompanyInstallmentPaymentsNumberOfInstallments" id="fbio_PartnerCompanyInstallmentPaymentsNumberOfInstallments" type="xbrli:integerItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" />
  <xsd:element name="GainLossOnSettlementOfPartnerCompanyInstallmentPayments" id="fbio_GainLossOnSettlementOfPartnerCompanyInstallmentPayments" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="credit" />
  <xsd:element name="PartnerCompanyInstallmentPaymentsLicenses" id="fbio_PartnerCompanyInstallmentPaymentsLicenses" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" xbrli:balance="credit" />
  <xsd:element name="SeriesC2WarrantsMember" id="fbio_SeriesC2WarrantsMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="InstallmentUponExecutionOfSettlementAgreementMember" id="fbio_InstallmentUponExecutionOfSettlementAgreementMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="InstallmentOnDecember12024Member" id="fbio_InstallmentOnDecember12024Member" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="InstallmentOnJanuary152025Member" id="fbio_InstallmentOnJanuary152025Member" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="AgreementWithPartnerCompaniesTerm" id="fbio_AgreementWithPartnerCompaniesTerm" type="xbrli:durationItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="AgreementWithPartnerCompaniesPercentageOfStockOwned" id="fbio_AgreementWithPartnerCompaniesPercentageOfStockOwned" type="dtr-types:percentItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="AgreementWithPartnerCompaniesPeriodForPaymentOfEquityFees" id="fbio_AgreementWithPartnerCompaniesPeriodForPaymentOfEquityFees" type="xbrli:durationItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="AgreementWithPartnerCompaniesPercentageOfGrossAmountOfAnySuchEquityOrDebtFinancing" id="fbio_AgreementWithPartnerCompaniesPercentageOfGrossAmountOfAnySuchEquityOrDebtFinancing" type="dtr-types:percentItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="AgreementWithPartnerCompaniesPercentageOfAnnualNetAssetsPayableAsCashFee" id="fbio_AgreementWithPartnerCompaniesPercentageOfAnnualNetAssetsPayableAsCashFee" type="dtr-types:percentItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="AgreementWithPartnerCompaniesPeriodForPaymentOfAnnualCashFee" id="fbio_AgreementWithPartnerCompaniesPeriodForPaymentOfAnnualCashFee" type="xbrli:durationItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="AgreementWithPartnerCompaniesChangeInControlFeeDescription" id="fbio_AgreementWithPartnerCompaniesChangeInControlFeeDescription" type="xbrli:stringItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="FortressBiotechIncMember" id="fbio_FortressBiotechIncMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="SegmentExpenditureAdditionToIntangibleAssets" id="fbio_SegmentExpenditureAdditionToIntangibleAssets" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="debit" />
  <xsd:element name="ResearchAndDevelopmentExpenseStockBasedCompensation" id="fbio_ResearchAndDevelopmentExpenseStockBasedCompensation" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="debit" />
  <xsd:element name="SellingGeneralAndAdministrativeExpenseShareBasedCompensation" id="fbio_SellingGeneralAndAdministrativeExpenseShareBasedCompensation" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="debit" />
  <xsd:element name="PercentageOfOutstandingLoanPrincipalAmountPrepaymentCharge" id="fbio_PercentageOfOutstandingLoanPrincipalAmountPrepaymentCharge" type="dtr-types:percentItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="EmployeeStockPurchasePlanOfferingFairValueReckoningPercentage" id="fbio_EmployeeStockPurchasePlanOfferingFairValueReckoningPercentage" type="dtr-types:percentItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" />
  <xsd:element name="ClassOfWarrantOrRightsExercisedWeightedAverageIntrinsicValue" id="fbio_ClassOfWarrantOrRightsExercisedWeightedAverageIntrinsicValue" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="debit" />
  <xsd:element name="PercentageOfRentableArea" id="fbio_PercentageOfRentableArea" type="dtr-types:percentItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="CybersecurityIncidentAmountTransferredToFraudulentAccounts" id="fbio_CybersecurityIncidentAmountTransferredToFraudulentAccounts" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="credit" />
  <xsd:element name="CybersecurityIncidentRecoveryOfPortionOfFundsTransferredEarlierToFraudulentAccounts" id="fbio_CybersecurityIncidentRecoveryOfPortionOfFundsTransferredEarlierToFraudulentAccounts" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="debit" />
  <xsd:element name="WorcesterMassachusettsMember" id="fbio_WorcesterMassachusettsMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="Rule10b51ArrangementModifiedFlag" id="fbio_Rule10b51ArrangementModifiedFlag" type="xbrli:booleanItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="NonRule10b51ArrangementModifiedFlag" id="fbio_NonRule10b51ArrangementModifiedFlag" type="xbrli:booleanItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="FiniteLivedIntangibleAssetsAccumulatedImpairment" id="fbio_FiniteLivedIntangibleAssetsAccumulatedImpairment" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" xbrli:balance="credit" />
  <xsd:element name="ProceedsFromLongTermDebtExcludingLineOfCredit" id="fbio_ProceedsFromLongTermDebtExcludingLineOfCredit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="debit" />
  <xsd:element name="LossRecoveryOfCosts" id="fbio_LossRecoveryOfCosts" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="credit" />
  <xsd:element name="LongTermIncentivePlanMember" id="fbio_LongTermIncentivePlanMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="EmployeesAndNonEmployeesMember" id="fbio_EmployeesAndNonEmployeesMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="DeferredTaxLiabilitiesStateTaxes" id="fbio_DeferredTaxLiabilitiesStateTaxes" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" xbrli:balance="credit" />
  <xsd:element name="BoardServicesAgreementMember" id="fbio_BoardServicesAgreementMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="CaribeBioadvisorsMember" id="fbio_CaribeBioadvisorsMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="EmrosiMember" id="fbio_EmrosiMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="OperatingLeaseLiabilityReversed" id="fbio_OperatingLeaseLiabilityReversed" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" xbrli:balance="debit" />
  <xsd:element name="PropertyPlantAndEquipmentWriteOff" id="fbio_PropertyPlantAndEquipmentWriteOff" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="credit" />
  <xsd:element name="OperatingLeaseRightOfUseAssetWriteOff" id="fbio_OperatingLeaseRightOfUseAssetWriteOff" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="credit" />
  <xsd:element name="PostEffectiveAmendmentOfShelfRegistration2024IssuedToPreferredStockHoldersMember" id="fbio_PostEffectiveAmendmentOfShelfRegistration2024IssuedToPreferredStockHoldersMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="PostEffectiveAmendmentOfShelfRegistration2024NovemberProspectusMember" id="fbio_PostEffectiveAmendmentOfShelfRegistration2024NovemberProspectusMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="PostEffectiveAmendmentOfShelfRegistration2024DecemberProspectusMember" id="fbio_PostEffectiveAmendmentOfShelfRegistration2024DecemberProspectusMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="SaleOfStockNumberOfSharesPerUnit" id="fbio_SaleOfStockNumberOfSharesPerUnit" type="xbrli:sharesItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="SaleOfStockNumberOfWarrantsPerUnit" id="fbio_SaleOfStockNumberOfWarrantsPerUnit" type="xbrli:sharesItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="PriorOaktreeAgreementMember" id="fbio_PriorOaktreeAgreementMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="January2025WarrantsMember" id="fbio_January2025WarrantsMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="EquityOfferingMember" id="fbio_EquityOfferingMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="LegalExpenseReimbursement" id="fbio_LegalExpenseReimbursement" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="debit" />
  <xsd:element name="MilestonePaymentsReceivableLicensingAgreements" id="fbio_MilestonePaymentsReceivableLicensingAgreements" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="debit" />
  <xsd:element name="PercentageToBeReceivedOnThirdPartyLicensingRevenue" id="fbio_PercentageToBeReceivedOnThirdPartyLicensingRevenue" type="dtr-types:percentItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="MaximumAmountsToBeReceivedOnThirdPartyLicensingRevenue" id="fbio_MaximumAmountsToBeReceivedOnThirdPartyLicensingRevenue" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="debit" />
  <xsd:element name="Mergeragreementmaximumcontingentconsiderationpershareforeachoutstandingshares" id="fbio_Mergeragreementmaximumcontingentconsiderationpershareforeachoutstandingshares" type="dtr-types:perShareItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" />
  <xsd:element name="DebtInstrumentPercentageOfPrincipalBalanceDue" id="fbio_DebtInstrumentPercentageOfPrincipalBalanceDue" type="dtr-types:percentItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" />
  <xsd:element name="UricaMember" id="fbio_UricaMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="FirstSpecifiedPeriodOrConditionMember" id="fbio_FirstSpecifiedPeriodOrConditionMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="SecondSpecifiedPeriodOrConditionMember" id="fbio_SecondSpecifiedPeriodOrConditionMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="JM17LicenseAgreementForIntellectualPropertyRightsMember" id="fbio_JM17LicenseAgreementForIntellectualPropertyRightsMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="JM17TerminationAndTransferAgreementMember" id="fbio_JM17TerminationAndTransferAgreementMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="NumberOfTranchesOfSharesToBeIssued" id="fbio_NumberOfTranchesOfSharesToBeIssued" type="xbrli:integerItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="ReimbursementPayableLicensingAgreements" id="fbio_ReimbursementPayableLicensingAgreements" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="credit" />
  <xsd:element name="DevelopmentMilestonePayableUSLicensingAgreements" id="fbio_DevelopmentMilestonePayableUSLicensingAgreements" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="credit" />
  <xsd:element name="DevelopmentMilestonePayableOutsideUSLicensingAgreements" id="fbio_DevelopmentMilestonePayableOutsideUSLicensingAgreements" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="credit" />
  <xsd:element name="SalesMilestonePayableLicensingAgreements" id="fbio_SalesMilestonePayableLicensingAgreements" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="credit" />
  <xsd:element name="AnnualNetSalesUsedAsBasisForMilestonesPayableLicensingAgreements" id="fbio_AnnualNetSalesUsedAsBasisForMilestonesPayableLicensingAgreements" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="credit" />
  <xsd:element name="PeriodNotToCompete" id="fbio_PeriodNotToCompete" type="xbrli:durationItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="ShareRepurchaseConsideration" id="fbio_ShareRepurchaseConsideration" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="debit" />
  <xsd:element name="TerminationPaymentsReceivable" id="fbio_TerminationPaymentsReceivable" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="debit" />
  <xsd:element name="DevelopmentAndRegulatoryPaymentsReceivable" id="fbio_DevelopmentAndRegulatoryPaymentsReceivable" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="debit" />
  <xsd:element name="MilestonesPayable" id="fbio_MilestonesPayable" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="credit" />
  <xsd:element name="MilestonePaid" id="fbio_MilestonePaid" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="debit" />
  <xsd:element name="EmrosiLicenseCollaborationAndAssignmentAgreementForDevelopmentAndCommercializationMember" id="fbio_EmrosiLicenseCollaborationAndAssignmentAgreementForDevelopmentAndCommercializationMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="QbexzaAssetPurchaseAgreementMember" id="fbio_QbexzaAssetPurchaseAgreementMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="QbexzaLicenseAgreementForDevelopmentAndCommercializationByCounterpartyMember" id="fbio_QbexzaLicenseAgreementForDevelopmentAndCommercializationByCounterpartyMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="AccutaneLicenseAndSupplyAgreementMember" id="fbio_AccutaneLicenseAndSupplyAgreementMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="PeriodOfRoyaltyPayable" id="fbio_PeriodOfRoyaltyPayable" type="xbrli:durationItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="ReductionInMilestonePaymentsReceivableIfNetSalesExceedFourBillionYenInSingleYeardevelopmentAndRegulatoryPaymentsReceivable" id="fbio_ReductionInMilestonePaymentsReceivableIfNetSalesExceedFourBillionYenInSingleYeardevelopmentAndRegulatoryPaymentsReceivable" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="debit" />
  <xsd:element name="NumberOfSalesBasedMilestones" id="fbio_NumberOfSalesBasedMilestones" type="xbrli:integerItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="PeriodOfAgreement" id="fbio_PeriodOfAgreement" type="xbrli:durationItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="PeriodOfWrittenNoticeToTerminateAgreementWithoutCause" id="fbio_PeriodOfWrittenNoticeToTerminateAgreementWithoutCause" type="xbrli:durationItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="VyneAssetPurchaseAgreementMember" id="fbio_VyneAssetPurchaseAgreementMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="AssetPurchaseRoyaltyAndRelatedAgreementsWithCrystalisMember" id="fbio_AssetPurchaseRoyaltyAndRelatedAgreementsWithCrystalisMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="AvenueShareRepurchaseAgreementMember" id="fbio_AvenueShareRepurchaseAgreementMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="DeconsolidationOfCommonStockWarrants" id="fbio_DeconsolidationOfCommonStockWarrants" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="debit" />
  <xsd:element name="SettlementOfPartnerCompanyPayables" id="fbio_SettlementOfPartnerCompanyPayables" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="debit" />
  <xsd:element name="RepaymentsOfDebtPrincipal" id="fbio_RepaymentsOfDebtPrincipal" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="credit" />
  <xsd:element name="RepaymentsOfDebtInterest" id="fbio_RepaymentsOfDebtInterest" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="credit" />
  <xsd:element name="PaymentsOfDebtYieldProtectionPremium" id="fbio_PaymentsOfDebtYieldProtectionPremium" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="credit" />
  <xsd:element name="ProceedsFromContractTermination" id="fbio_ProceedsFromContractTermination" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="debit" />
  <xsd:element name="Excesspershareexercisepriceofwarrants" id="fbio_Excesspershareexercisepriceofwarrants" type="dtr-types:perShareItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" />
  <xsd:element name="SharesWithheldRelatedToNetSettlementOfWarrants" id="fbio_SharesWithheldRelatedToNetSettlementOfWarrants" type="xbrli:sharesItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="AssetAcquisitionConsiderationInCash" id="fbio_AssetAcquisitionConsiderationInCash" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="credit" />
  <xsd:element name="TransactionRelatedExpenses" id="fbio_TransactionRelatedExpenses" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="debit" />
  <xsd:element name="AssetAcquisitionConsiderationUpfrontPayment" id="fbio_AssetAcquisitionConsiderationUpfrontPayment" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="credit" />
  <xsd:element name="AssetAcquisitionConsiderationSubsequentPayment" id="fbio_AssetAcquisitionConsiderationSubsequentPayment" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="credit" />
  <xsd:element name="AssetAcquisitionConsiderationSubsequentPaymentDuePeriod" id="fbio_AssetAcquisitionConsiderationSubsequentPaymentDuePeriod" type="xbrli:durationItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="AssetAcquisitionConsiderationThresholdNetAssetsConsideredForDelayInSubsequentPayment" id="fbio_AssetAcquisitionConsiderationThresholdNetAssetsConsideredForDelayInSubsequentPayment" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" xbrli:balance="debit" />
  <xsd:element name="AssetAcquisitionInterestRateOnOutstandingLiability" id="fbio_AssetAcquisitionInterestRateOnOutstandingLiability" type="dtr-types:percentItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="PercentageReductionInRoyaltyPaymentPercentageUponLaunchOfGenericCompetitor" id="fbio_PercentageReductionInRoyaltyPaymentPercentageUponLaunchOfGenericCompetitor" type="dtr-types:percentItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="ProceedsFromRoyaltyPayments" id="fbio_ProceedsFromRoyaltyPayments" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="debit" />
  <xsd:element name="CutiaTherapeuticsHkLimitedMember" id="fbio_CutiaTherapeuticsHkLimitedMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="ClassOfWarrantOrRightWarrantsExercisedForShares" id="fbio_ClassOfWarrantOrRightWarrantsExercisedForShares" type="xbrli:sharesItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="DebtInstrumentInterestOnlyPeriodExtendedPeriod" id="fbio_DebtInstrumentInterestOnlyPeriodExtendedPeriod" type="xbrli:durationItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="DisposalGroupNotDiscontinuedOperationConsiderationUpfrontPaymentReceivable" id="fbio_DisposalGroupNotDiscontinuedOperationConsiderationUpfrontPaymentReceivable" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" xbrli:balance="debit" />
  <xsd:element name="UponOccurrenceOfDevelopmentAndRegulatoryEventsMember" id="fbio_UponOccurrenceOfDevelopmentAndRegulatoryEventsMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="DisposalGroupNotDiscontinuedOperationConsiderationMilestonePaymentReceivable" id="fbio_DisposalGroupNotDiscontinuedOperationConsiderationMilestonePaymentReceivable" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" xbrli:balance="debit" />
  <xsd:element name="EachIndicationAfterOccurrenceOfDevelopmentAndRegulatoryEventsMember" id="fbio_EachIndicationAfterOccurrenceOfDevelopmentAndRegulatoryEventsMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="DisposalGroupNotDiscontinuedOperationConsiderationExpectedPercentageOfAllFuturePaymentsAndRoyaltiesPayable" id="fbio_DisposalGroupNotDiscontinuedOperationConsiderationExpectedPercentageOfAllFuturePaymentsAndRoyaltiesPayable" type="dtr-types:percentItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" />
  <xsd:element name="AccountsPayableAndAccruedExpensesTable" id="fbio_AccountsPayableAndAccruedExpensesTable" type="xbrli:stringItemType" substitutionGroup="xbrldt:hypercubeItem" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="AccountsPayableAndAccruedExpensesLineItems" id="fbio_AccountsPayableAndAccruedExpensesLineItems" type="xbrli:stringItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="NumberOfReportableSegmentsNotDisclosedFlag" id="fbio_NumberOfReportableSegmentsNotDisclosedFlag" type="xbrli:booleanItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="GainFromReversalOfFinancingRelatedObligation" id="fbio_GainFromReversalOfFinancingRelatedObligation" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="credit" />
  <xsd:element name="FairValueOfAssetsInRepurchaseTransaction" id="fbio_FairValueOfAssetsInRepurchaseTransaction" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" xbrli:balance="debit" />
  <xsd:element name="GainLossOnRecovery" id="fbio_GainLossOnRecovery" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="credit" />
  <xsd:element name="LeaseLiabilitiesArisingFromObtainingRightOfUseAssets" id="fbio_LeaseLiabilitiesArisingFromObtainingRightOfUseAssets" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="debit" />
  <xsd:element name="OaktreeWarrants2025Member" id="fbio_OaktreeWarrants2025Member" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="AdjustmentsToAdditionalPaidInCapitalPartnerCompaniesOfferingsNetAndWarrantExercises" id="fbio_AdjustmentsToAdditionalPaidInCapitalPartnerCompaniesOfferingsNetAndWarrantExercises" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="credit" />
  <xsd:element name="MinimumNetSalesToBeAchieved" id="fbio_MinimumNetSalesToBeAchieved" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="credit" />
  <xsd:element name="ReductionInDebtCovenantMember" id="fbio_ReductionInDebtCovenantMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="LoansDueOnSeptember302027Member" id="fbio_LoansDueOnSeptember302027Member" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="LoansDueOnDecember302027Member" id="fbio_LoansDueOnDecember302027Member" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="LoansDueOnMarch312028Member" id="fbio_LoansDueOnMarch312028Member" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="SecondAmendmentAgreementMember" id="fbio_SecondAmendmentAgreementMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="EffectiveIncomeTaxRateReconciliationNondeductibleExpenseTransactionCostsAmount" id="fbio_EffectiveIncomeTaxRateReconciliationNondeductibleExpenseTransactionCostsAmount" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="debit" />
  <xsd:element name="EffectiveIncomeTaxRateReconciliationNondeductibleExpenseTransactionCostsPercentage" id="fbio_EffectiveIncomeTaxRateReconciliationNondeductibleExpenseTransactionCostsPercentage" type="dtr-types:percentItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="EffectiveIncomeTaxRateReconciliationSection162mCompensationDisallowance" id="fbio_EffectiveIncomeTaxRateReconciliationSection162mCompensationDisallowance" type="dtr-types:percentItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="DebtCovenantNoLongerApplyMember" id="fbio_DebtCovenantNoLongerApplyMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="ThresholdPercentageOfProceedsToBeTransferred" id="fbio_ThresholdPercentageOfProceedsToBeTransferred" type="dtr-types:percentItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" />
  <xsd:element name="AreaOfLandOperatingSublease" id="fbio_AreaOfLandOperatingSublease" type="dtr-types:areaItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" />
  <xsd:element name="LesseeOperatingSubleaseBaseRentReceivable" id="fbio_LesseeOperatingSubleaseBaseRentReceivable" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" xbrli:balance="debit" />
  <xsd:element name="DebtInstrumentCovenantMinimumLiquidityAmount" id="fbio_DebtInstrumentCovenantMinimumLiquidityAmount" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" xbrli:balance="debit" />
  <xsd:element name="EuniceKennedyShriverNationalInstituteOfChildHealthAndHumanDevelopmentMember" id="fbio_EuniceKennedyShriverNationalInstituteOfChildHealthAndHumanDevelopmentMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="FoamFranchiseProductsMember" id="fbio_FoamFranchiseProductsMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="NewYorkCityMember" id="fbio_NewYorkCityMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="OaktreeWarrants2024And2025Member" id="fbio_OaktreeWarrants2024And2025Member" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="LicenseAgreementNumberOfProductsAgreedToAcquire" id="fbio_LicenseAgreementNumberOfProductsAgreedToAcquire" type="xbrli:integerItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="PercentageOfWithholdingTax" id="fbio_PercentageOfWithholdingTax" type="dtr-types:percentItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="PaymentsAsPercentageOfFinancingProceeds" id="fbio_PaymentsAsPercentageOfFinancingProceeds" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="credit" />
  <xsd:element name="ParentCompanyAndItsSubsidiariesMember" id="fbio_ParentCompanyAndItsSubsidiariesMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="EffectOfSubsidiaryDeemedDividendsOnNetIncomeLossPerShareCalculation" id="fbio_EffectOfSubsidiaryDeemedDividendsOnNetIncomeLossPerShareCalculation" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="debit" />
  <xsd:element name="LicenseAgreementConsiderationPaidInEquity" id="fbio_LicenseAgreementConsiderationPaidInEquity" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" xbrli:balance="credit" />
  <xsd:element name="AdjustmentsToAdditionalPaidInCapitalExchangeOfPartnerCompanyPreferredShares" id="fbio_AdjustmentsToAdditionalPaidInCapitalExchangeOfPartnerCompanyPreferredShares" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="credit" />
  <xsd:element name="AdjustmentsToAdditionalPaidInCapitalReclassificationOfPartnerCompanyPreferredShares" id="fbio_AdjustmentsToAdditionalPaidInCapitalReclassificationOfPartnerCompanyPreferredShares" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="credit" />
  <xsd:element name="RedemptionPriceForPreferredStock" id="fbio_RedemptionPriceForPreferredStock" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="credit" />
</xsd:schema>
