75000 - Document - Document And Entity Information
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75010 - Statement - Consolidated Statements of Financial Position
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75020 - Statement - Consolidated Statements of Financial Position (Parentheticals)
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75030 - Statement - Consolidated Statements of Loss and Comprehensive Loss
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75040 - Statement - Consolidated Statements of Changes in Shareholders' Deficit
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75050 - Statement - Consolidated Statements of Cash Flows
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995457 - Disclosure - Cybersecurity Risk Management, Strategy, and Governance
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995467 - Disclosure - Note 1 - Reporting Entity
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995477 - Disclosure - Note 2 - Significant Accounting Policies
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995487 - Disclosure - Note 3 - Cash and Cash Equivalents
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995497 - Disclosure - Note 4 - Restricted Cash and Restricted Cash Equivalents
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995507 - Disclosure - Note 5 - Prepaid Expenses
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995517 - Disclosure - Note 6 - Property and Equipment
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995527 - Disclosure - Note 7 - Right-of-use Assets, Operating Leases
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995537 - Disclosure - Note 8 - Other Long-Term Assets
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995547 - Disclosure - Note 9 - Fair Value Measurements and Financial Instruments
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995557 - Disclosure - Note 10 - Accrued Liabilities
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995567 - Disclosure - Note 11 - Commitments and Contingencies
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995577 - Disclosure - Note 12 - Related Party Transactions
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995587 - Disclosure - Note 13 - Share Capital
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995597 - Disclosure - Note 14 - Warrants
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995607 - Disclosure - Note 15 - Stock-based Compensation
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995617 - Disclosure - Note 16 - Collaborative Agreements
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995627 - Disclosure - Note 17 - Income Taxes
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995637 - Disclosure - Note 18 - Subsequent Events
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995647 - Disclosure - Note 2 - Significant Accounting Policies (Policies)
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995657 - Disclosure - Note 2 - Significant Accounting Policies (Tables)
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995667 - Disclosure - Note 5 - Prepaid Expenses (Tables)
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995677 - Disclosure - Note 6 - Property and Equipment (Tables)
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995687 - Disclosure - Note 7 - Right-of-use Assets, Operating Leases (Tables)
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995697 - Disclosure - Note 7 - Investments (Tables)
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995707 - Disclosure - Note 8 - Fair Value Measurements and Financial Instruments (Tables)
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995717 - Disclosure - Note 10 - Accrued Liabilities (Tables)
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995727 - Disclosure - Note 11 - Commitments and Contingencies (Tables)
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995737 - Disclosure - Note 13 - Share Capital (Tables)
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995747 - Disclosure - Note 14 - Warrants (Tables)
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995757 - Disclosure - Note 15 - Stock-based Compensation (Tables)
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995767 - Disclosure - Note 17 - Income Taxes (Tables)
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995777 - Disclosure - Note 2 - Significant Accounting Policies (Details Textual)
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995787 - Disclosure - Note 3 - Cash and Cash Equivalents (Details Textual)
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995797 - Disclosure - Note 4 - Restricted Cash and Restricted Cash Equivalents (Details Textual)
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995807 - Disclosure - Note 5 - Prepaid Expenses - Prepaid Expenses and Other Assets (Details)
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995817 - Disclosure - Note 6 - Property and Equipment - Property and Equipment (Details)
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995827 - Disclosure - Note 6 - Property and Equipment (Details Textual)
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995837 - Disclosure - Note 7 - Right-of-use Assets, Operating Leases - Schedule of Right-of-use Assets (Details)
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995847 - Disclosure - Note 7 - Investments - Investments (Details)
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995857 - Disclosure - Note 9 - Fair Value Measurements and Financial Instruments - Assets Measured on a Recurring Basis (Details)
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995867 - Disclosure - Note 10 - Accrued Liabilities - Accrued Expenses (Details)
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995877 - Disclosure - Note 11 - Commitments and Contingencies - Leases (Details)
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995887 - Disclosure - Note 11 - Commitments and Contingencies - Operating Lease Cost (Details)
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995897 - Disclosure - Note 11 - Commitments and Contingencies - Schedule of Future Minimum Payments of Lease Liabilities (Details)
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995907 - Disclosure - Note 11 - Commitments and Contingencies - Schedule of Future Minimum Payments of Lease Liabilities (Details) 2
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995917 - Disclosure - Note 11 - Commitments and Contingencies (Details Textual)
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995927 - Disclosure - Note 12 - Related party transactions (Details Textual)
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995937 - Disclosure - Note 13 - Share Capital (Details Textual)
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995947 - Disclosure - Note 13 - Share Capital - Loss Per Share (Details)
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995957 - Disclosure - Note 13 - Share Capital - Schedule of Total Anti-dilutive Shares (Details)
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995967 - Disclosure - Note 14 - Warrants (Details Textual)
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995977 - Disclosure - Note 14 - Warrants - Summary of Warrants Issued, Estimated and Record (Details))
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995987 - Disclosure - Note 14 - Warrants - Summary of Warrant Activity (Details)
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995997 - Disclosure - Note 14 - Warrants - Summary of Number of Outstanding Warrants by Exercise Price and Date of Expiration (Details)
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996007 - Disclosure - Note 15 - Stock-based Compensation (Details Textual)
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996017 - Disclosure - Note 15 - Stock-based Compensation - Stock Option Activity (Details)
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996027 - Disclosure - Note 15 - Stock-based Compensation - Weighted Average Assumptions (Details)
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996037 - Disclosure - Note 15 - Stock-based Compensation - Vesting Terms of Options Granted (Details)
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996047 - Disclosure - Note 15 - Stock-based Compensation - Vesting Terms of Options Granted (Details) (Parentheticals)
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996057 - Disclosure - Note 15 - Stock-based Compensation - Share-based Payment Expense (Details)
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996067 - Disclosure - Note 16 - Collaborative Agreements (Details Textual)
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996077 - Disclosure - Note 17 - Income Taxes (Details Textual)
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996087 - Disclosure - Note 17 - Income Taxes - Loss Before Income Taxes (Details)
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996097 - Disclosure - Note 17 - Income Taxes - Provision for Income Taxes (Details)
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996107 - Disclosure - Note 17 - Income Taxes - Deferred Tax Assets (Details)
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996117 - Disclosure - Note 18 - Subsequent Events (Details Textual)
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Proceeds from Sale of Property, Plant, and Equipment
Proceeds from Sale of Property, Plant, and Equipment, Total
Proceeds from disposition of fixed assets
Proceeds from disposal of property and equipment
Income (Loss) from Continuing Operations before Income Taxes, Foreign
Loss attributed to Canadian operations
Options with Three Year Vesting [Member]
Information pertaining to options with three year vesting.
Share-Based Compensation Arrangement by Share-Based Payment Award, Non-Option Equity Instruments, Outstanding, Number
Common shares issuable upon exercise, Ending
Common shares issuable upon exercise, Beginning
Employee Stock Purchase Plan, Stock Purchase Price, Percent
apto_EmployeeStockPurchasePlanStockPurchasePricePercent
The percent of stock purchase price under an employee stock purchase plan.
Entity Incorporation, State or Country Code
Increase (Decrease) in Accounts Payable
Increase (Decrease) in Accounts Payable, Total
Reduced the accounts payable
Accounts payable
September 2024 Common Share Issuance [Member]
September 2024 common share issuance.
September 2024 Common Share Issuance [Member]
Plan Name [Axis]
Equity [Abstract]
Entity Current Reporting Status
Negative shareholder's equity
Negative Shareholder's Equity
Negative shareholder's equity.
Operating Expenses [Abstract]
Operating expenses:
Level 2 [Member]
Level 2 [Member]
Net deferred tax asset
Deferred Tax Assets, Net of Valuation Allowance
Commitments and Contingencies
Commitments and Contingencies Disclosure [Text Block]
Share-Based Payment Arrangement, Tranche Three [Member]
Officer Two [Member]
Represents officer two.
Investment, Policy [Policy Text Block]
Investments
Tabular disclosure of the carrying amounts of right-of-use assets. This disclosure includes current assets and noncurrent assets.
Schedule of Right-of-use Assets [Table Text Block]
Schedule of Right-of-use Assets
Document Fiscal Period Focus
Loan interest rate
Debt Instrument, Interest Rate, Stated Percentage
Loan interest rate
Entity Shell Company
Other accrued expenses
Other accrued liabilities
Other Accrued Liabilities, Current
Segment Reporting, Policy [Policy Text Block]
Segment reporting
Cash and Cash Equivalent
Cash and Cash Equivalents, at Carrying Value, Total
Cash and cash equivalents
Minimum amount available under single advance
Minimum Amount Available Under Single Advance
Minimum amount available under single advance.
Accounts payable, related party
Accounts payable, related party
Increase (Decrease) in Accounts Payable, Related Parties
Cybersecurity Risk Management, Strategy, and Governance [Abstract]
Common Stock, Shares, Issued
Common Stock, Share issued
Cybersecurity Risk Management Positions or Committees Responsible Report to Board [Flag]
Cybersecurity Risk Board of Directors Oversight [Text Block]
Schedule of Future Minimum Payments of Lease Liabilities
Schedule of Future Minimum Payments of Lease Liabilities [Table Text Block]
Schedule of Future Minimum Payments of Lease Liabilities [Table Text Block]
Asset Class [Domain]
September Five Two Thousand Twenty Nine [Member]
September five two thousand twenty nine.
September 5, 2029 [Member]
Statement [Table]
Right-of-Use Asset Obtained in Exchange for Operating Lease Liability
Additions to right-of-use assets
Additions to right-of-use assets, operating leases
Internal Revenue Service (IRS) [Member]
Prepaid expenses
Increase (Decrease) in Prepaid Expense
Prepaid expenses
Stock and Warrants Issued During Period Value
Stock and warrants issued during period value.
Common shares and warrants issued pursuant to the January 2024 Public Offering
Common shares and warrants issued under the November/January 2024 Public Offering
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Grants in Period, Weighted Average Grant Date Fair Value
Grant date fair value
Stock and Warrants Issued During Period Shares Subscription Agreement
Stock and warrants issued during period shares subscription agreement.
Common shares and warrants under the Registered Direct Offering/ issued pursuant to the Hanmi Private Placement (in shares)
Money Market Accounts [Member]
Information pertaining to money market accounts.
Investment, Unrealized gain/(loss)
Debt Securities, Available-for-Sale, Accumulated Gross Unrealized Gain (Loss), before Tax
Debt Securities, Available-for-Sale, Accumulated Gross Unrealized Gain (Loss), before Tax, Total
Investment, Unrealized gain/(loss)
Statement [Line Items]
Warrant [Member]
Warrant [Member]
Outstanding Warrants to Purchase Common Shares [Member]
Entity Filer Category
Liabilities and Equity
Total liabilities and shareholders' deficit
Payables and Accruals [Abstract]
Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercisable, Weighted Average Exercise Price (in dollars per share)
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Weighted Average Exercise Price
Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercisable, Weighted Average Exercise Price (in dollars per share)
Long-Lived Tangible Asset [Axis]
Interest payments frequency
Debt Instrument, Frequency of Periodic Payment
Exclusive License to CG806 in China, Regulatory Milestones [Member]
Related to an agreement regulatory milestone.
Cybersecurity Risk Third Party Oversight and Identification Processes [Flag]
Investment Tax Credit Carryforward [Member]
Series A Warrants [Member]
Series A warrants.
Series A Warrants [Member]
Hanmi Facility Agreement [Member]
Hanmi Facility Agreement.
Hanmi Facility Agreement [Member]
January Thirty Two Thousand And Twenty Nine [Member]
January thirty two thousand and twenty nine.
January 30, 2029 [Member]
Valuation allowance
Deferred Tax Assets, Valuation Allowance
Effective Income Tax Rate Reconciliation, at Federal Statutory Income Tax Rate, Percent
Effective Income Tax Rate Reconciliation, at Federal Statutory Income Tax Rate, Percent
Statutory Canadian corporate tax rate
Shares Issued, Price Per Share (in dollars per share)
Shares Issued, Price Per Share
Issue-date Aptose share price
Common share exchange price
Subsequent Event [Line Items]
Effective Income Tax Rate Reconciliation, Nondeductible Expense, Amount
Effective Income Tax Rate Reconciliation, Nondeductible Expense, Amount, Total
Non-taxable or non-deductible items
Cybersecurity Risk Management Third Party Engaged [Flag]
Documents Incorporated by Reference [Text Block]
Share-based Payment Arrangement, Tranche Four [Member]
Fourth portion of award under share-based payment arrangement differentiated by vesting feature, including, but not limited to, performance measure or service period.
Investment Income, Interest
Interest income
Income Tax Jurisdiction [Axis]
January 31, 2029 [Member]
January Thirty One Thousand And Twenty Nine [Member]
January thirty one thousand and twenty nine.
Cash and Cash Equivalents, Restricted Cash and Cash Equivalents, Policy [Policy Text Block]
Restricted cash equivalents
Restricted cash and restricted cash equivalents
Non-current assets:
Assets, Noncurrent [Abstract]
Non-current assets:
2023 Committed Equity Facility [Member]
Two Thousand Twenty Three Committed Equity Facility [Member]
Two thousand twenty three committed equity facility.
Related Party [Member]
Related Party [Member]
Related Party [Member]
Significant Accounting Policies [Text Block]
Significant accounting policies
Property, Plant and Equipment [Line Items]
Class Of Warrant Or Right Exercise Price Of Warrants Or Rights Two
Class of warrant or right exercise price of warrants or rights two.
Exercise price
Exercise price
Accrued liabilities to related party
Accrued liabilities to related party current
Accrued liabilities to related party current.
Restricted Cash Equivalent
Restricted Cash Equivalents, Total
Restricted cash equivalents
Measurement Input, Risk Free Interest Rate [Member]
Accounting Policy [Line Item]
Accounting Policy.
Weighted average exercise price, Exercised
Share Based Compensation Arrangement By Share Based Paymet Award Weighted Average Exercise Price Exercised
Share based compensation arrangement by share based paymet award weighted average exercise price exercised.
Maximum Number of Advances
Maximum number of advances.
Maximum number of advances
Vesting [Domain]
Stock options granted in the period (in shares)
Share-based Compensation Arrangement by Share-based Payment Award, Options, Grants in Period, Gross (in shares)
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Grants in Period, Gross
Percentage of shares outstanding for issuance of warrant
Percentage of shares outstanding for issuance of warrant.
Percentage of shares outstanding
Accounts payable
Increase Decrease In Account Payable
Increase decrease in account payable.
Cybersecurity Risk Management, Strategy, and Governance [Table]
Schedule of Earnings Per Share, Basic and Diluted [Table Text Block]
Schedule of Earnings Per Share, Basic and Diluted
Investment, Name [Axis]
Earnings Per Share, Basic, Total
Earnings Per Share, Basic
Net loss per common share, basic
Net loss per common share, basic
Effective Income Tax Rate Reconciliation, Tax Settlement, Amount
Effective Income Tax Rate Reconciliation, Tax Settlement, Amount, Total
Computed expected tax recovery
Options With Performance Criteria [Member]
Information pertaining to options with performance criteria.
Options With Performance Criteria [Member]
Stock Issued During Period, Value, Licensing Fee
Common shares issued pursuant to the Hanmi licensing fees
Value of stock issued as a result of licensing fee.
Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Number, Ending Balance (in shares)
Outstanding, options (in shares)
Outstanding, options (in shares)
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Number
Total current liabilities
Liabilities, Current
Current liabilities
Summary of Warrants Issued, Estimated and Record
Fair Value, Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation [Table Text Block]
Domestic Tax Jurisdiction [Member]
Class Of Warrant Or Right Outstanding One
Class of warrant or right outstanding one.
Shares issuable upon exercise
Effective Income Tax Rate Reconciliation [Table]
Continuing Vesting Options with No Service Requirement [Member]
Information regarding continuing vesting options with no service requirement.
Equity, Attributable to Parent [Abstract]
Shareholders' deficit:
Shareholders' deficit:
Entity Small Business
Accrued liabilities
Increase (Decrease) in Accrued Liabilities
Increase (Decrease) in Accrued Liabilities, Total
Retained Earnings (Accumulated Deficit)
Retained Earnings (Accumulated Deficit), Total
Deficit
Accumulated deficit
Entity Well-known Seasoned Issuer
Forfeited, options (in shares)
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Forfeitures in Period
ESPP [Member]
Employee Stock Purchase Plan [Member]
Employee stock purchase plan.
Common Shares and Warrants Issued In S1 Financing Amount
Common shares and warrants issued In S1 financing amount.
Common shares and warrants issued in S-1 financing
Sale of Stock, Price Per Share
Sale of stock price per share
Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercises in Period, Intrinsic Value
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercises in Period, Intrinsic Value
Warrants and Rights Outstanding, Measurement Input
Measurement input
Share-Based Payment Arrangement [Text Block]
Stock-based compensation
Organization, Consolidation and Presentation of Financial Statements [Abstract]
Two Thousand Twenty Five Committed Equity Facility [Member]
Two thousand twenty five committed equity facility.
2025 Committed Equity Facility [Member]
Share Based Compensation Arrangement By Share Based Paymet Award Weighted Average Exercise Price Exercisable
Share based compensation arrangement by share based paymet award weighted average exercise price exercisable.
Weighted average exercise price, Exercisable
Leases [Abstract]
Amendment Flag
Proceeds from Sale, Maturity and Collection of Investments
Proceeds from Sale, Maturity and Collection of Investments, Total
Maturity of investments, net
Warrants to purchase common shares, number of warrants
Class of Warrant or Right, Number of Securities Called by Warrants or Rights
Hanmi Pharmaceuticals Co Ltd [Member]
Hanmi Pharmaceuticals Co Ltd [Member]
Hanmi Pharmaceuticals Co., Ltd.
Hanmi Pharmaceuticals Co., Ltd. [Member]
Chief Executive Officer [Member]
CEO [Member]
Earnings Per Share, Policy [Policy Text Block]
Loss per share
Entity Address, Postal Zip Code
Share Based Compensation Arrangement By Share Based Paymet Award Weighted Average Exercise Price Granted
Share based compensation arrangement by share based paymet award weighted average exercise price granted.
Weighted average exercise price, Issued
Interest on Related Party Loan Payable [Member]
Interest on related party loan payable.
Warrants Disclosure [Text Block]
Warrants.
Warrants
Cash used in operating activities
Cash Provided by (Used in) Operating Activity, Including Discontinued Operation
Increase (Decrease) in Operating Lease Liability
Change in operating lease liability
Cash CDIC insured amount.
Cash C D I C Insured amount
CDIC insures deposits
Segment Reporting, CODM, Profit (Loss) Measure, How Used, Description
Common Shares [Member]
Common Stock [Member]
Common Stock [Member]
Cybersecurity Risk Role of Management [Text Block]
Tax Credit Carryforward, Amount
Tax Credit Carryforward, Amount
Public Offering [Member]
Represents information pertaining to public offering.
Public Offering [Member]
Share-based Compensation Arrangements by Share-based Payment Award, Options, Grants in Period, Weighted Average Exercise Price (in dollars per share)
Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Grants in Period, Weighted Average Exercise Price
Share-based Compensation Arrangements by Share-based Payment Award, Options, Grants in Period, Weighted Average Exercise Price (in dollars per share)
Related Party Transaction, Date
Loan is repayable date
Loan is repayable date
Accumulated Depreciation, Depletion and Amortization, Property, Plant, and Equipment
Accumulated Depreciation, Depletion and Amortization, Property, Plant, and Equipment, Total
Accumulated Depreciation, Depletion and Amortization, Property, Plant, and Equipment, Beginning Balance
Accumulated Depreciation, Depletion and Amortization, Property, Plant, and Equipment, Ending Balance
Accumulated depreciation
Series B Warrants [Member]
Series B warrants.
Series B Warrants [Member]
Proceeds From Warrant Exercise
Proceeds from warrant exercise.
Proceeds from warrant exercise
Entity Address, Address Line One
Schedule of Share-Based Payment Award, Stock Options, Valuation Assumptions [Table Text Block]
Schedule of Share-based Payment Award, Stock Options, Valuation Assumptions
Measurement Input Issue Date Fair Value [Member]
Measurement input issue date fair value.
Fair Value Hierarchy and NAV [Axis]
Earnings Per Share [Abstract]
Income Tax, Policy [Policy Text Block]
Income taxes
Cybersecurity Risk Materially Affected or Reasonably Likely to Materially Affect Registrant [Flag]
Common Shares Issued for Prefunded Warrants Exercise, Shares
Common shares issued for prefunded warrants exercise, shares.
Common shares issued pursuant to the exercise of the Pre-Funded Warrants, shares
Weighted average remaining contractual life (years)
Share Based Compensation Arrangement By Share Based Payment Award Non Option Equity Instruments Outstanding Weighted Average Remaining Contractual Life
Share based compensation arrangement by share based payment award non option equity instruments outstanding weighted average remaining contractual life.
Operating Lease, Right-of-Use Asset
Right-of-use assets, operating leases
Right-of use assets, operating leases, net
Total deferred tax assets
Deferred Tax Assets, Gross
Cybersecurity Risk Board Committee or Subcommittee Responsible for Oversight [Text Block]
Transaction Cost Including Placement Agent Fees and Professional Fees
Transaction cost including placement agent fees and professional fees.
Transaction cost including placement agent fees and professional fees
Transaction cost including placement agent fees and professional fees
Class of Warrant or Right [Axis]
Document Type
Collaborative Arrangement and Arrangement Other than Collaborative [Axis]
The amount of accrual of interest on investments.
apto_InterestAccruedOnInvestments
Accrued interest on investments
Accrued interest on investments
Warrants issued
Warrants issued.
Warrants Issued
Collaborative Arrangement and Arrangement Other than Collaborative [Domain]
Entity Central Index Key
June Two Thousand And Twenty four Registered Direct Offering [Member]
June two thousand and twenty four registered direct offering.
June 2024 Registered Direct Offering [Member]
Cybersecurity Risk Process for Informing Board Committee or Subcommittee Responsible for Oversight [Text Block]
Foreign exchange loss
Realized Gain (Loss), Foreign Currency Transaction, before Tax
Other Assets, Noncurrent [Abstract]
Stock issuance program authorized shares
Stock Issuance Program Authorized Shares
Stock issuance program authorized shares.
Cash, Cash Equivalent, Restricted Cash, and Restricted Cash Equivalent, Period Increase (Decrease), Including Exchange Rate Effect and Discontinued Operation
Decrease in cash, cash equivalents, restricted cash and restricted cash equivalent
Subsequent Event Type [Domain]
Fair Value Adjustment of Warrants
Change in fair value of warrant liability
Change in fair value of warrants
Change in fair value of warrants
Noncash operating lease expense
Noncash Operating Lease Expense
Noncash operating lease expense.
Antidilutive Securities Excluded from Computation of Earnings Per Share, Amount
Total anti-dilutive shares
Impairment of Long-Lived Assets to be Disposed of
Accumulated depreciation
Cash proceeds
Proceeds from Issuance of Warrants
Share-Based Payment Arrangement, Tranche One [Member]
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Remaining Contractual Term
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Remaining Contractual Term
Debt Securities, Available-for-Sale, Amortized Cost
Debt Securities, Available-for-Sale, Amortized Cost, Total
Investment, Cost
Debt Securities, Available-for-Sale
Debt Securities, Available-for-Sale, Total
Investment, Market value
Amount Agreed To Pay For Reasonable Expenses Under Purchase Agreement
Amount agreed to pay for reasonable expenses under purchase agreement.
Amount agreed to pay for reasonable expenses under purchase agreement
Document Financial Statement Error Correction [Flag]
ACP Warrants [Member]
ACP warrants.
Exercised, options (in shares)
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercises in Period
Common shares issued upon exercise of stock options (in shares)
Common shares issued upon exercise of stock options (in shares)
Other Prepaid Expense, Current
Other prepaid expenses
Canada Revenue Agency [Member]
Restructuring and Related Cost, Expected Cost
Restructuring and Related Cost, Expected Cost, Total
Retention bonuses
Repayments of Related Party Debt
Repayment of loan with related party
Accrued liabilities
Accrued liabilities to related party
Accrued Liabilities, Current
Total
Interest on lease liabilities
The amount of interest expense related to lease liabilities
Interest on lease liabilities
Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Line Items]
Current Fiscal Year End Date
Newbridge Warrants [Member]
Newbridge warrants.
Newbridge Warrants [Member]
Officer One [Member]
Represents officer one.
Hanmi Loan Agreement [Member]
Hanmi Loan Agreement.
Hanmi Loan Agreement [Member]
The 2020 ATM Offering [Member]
Information pertaining to the 2020 ATM Offering.
The 2020 ATM Offering [Member]
Share Based Compensation Arrangement By Share Based Paymet Award Non Option Outstanding Weighted Average Exercise Price
Share based compensation arrangement by share based paymet award non option outstanding weighted average exercise price.
Weighted average exercise price, Beginning
Weighted average exercise price, Ending
Entity Address, State or Province
Investment, Name [Domain]
Number of common shares held
Investment Owned, Balance, Shares
Research and Development Expense, Policy [Policy Text Block]
Research and development
Common Stock, Capital Shares Reserved for Future Issuance
Shares available for future issuance
Class of Warrant or Right [Domain]
Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Table Text Block]
Share-based Payment Arrangement, Expensed and Capitalized, Amount
Professional fees
Professional Fees
Stock Issued During Period, Value, Stock Options Exercised
Common shares issued upon exercise of stock options
Schedule of Deferred Tax Assets and Liabilities
Performance Shares [Member]
Subsequent Event [Member]
Subsequent Event [Member]
Stock Issued During Period Value Debt Conversion
Stock issued during period value debt conversion.
Common shares issued pursuant to Hanmi debt conversion
Property, Plant and Equipment [Abstract]
Deferred Tax Assets, Tax Credit Carryforwards, Research
Research and development tax credits
Other Assets, Noncurrent
Other long-term assets
Measurement Input, Expected Term [Member]
June Two Thousand And Twenty Four Pre Funded Warrant [Member]
June 2024 Pre-funded warrant.
June 2024 Pre-funded Warrants [Member]
Antidilutive Securities [Axis]
H C Wainwright [Member]
H.C. Wainwright.
H.C. Wainwright [Member]
Share-based Compensation Arrangement by Share-based Payment Award, Award Vesting Rights, Percentage
Share-Based Compensation Arrangement by Share-Based Payment Award, Award Vesting Rights, Percentage
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Outstanding, Aggregate Intrinsic Value
Reclassifications
Reclassifications [Policy Text Block]
Reclassifications.
Accounts payable to related party current
Accounts payable to related party current.
Accounts payable to related parties
Related Party Transaction [Axis]
Clinical Development and Global Regulatory Milestone, Second Indication
apto_ClinicalDevelopmentAndGlobalRegulatoryMilestoneSecondIndication
Represents the target clinical development and global regulatory milestones for the second indication.
Common Shares Issued for Prefunded Warrants Exercise, Value
Common shares issued pursuant to the exercise of the Pre-Funded Warrants, value
Common Shares Issued for Prefunded Warrants Exercise, Value
Clinical Development and Global Regulatory Milestone, First Indication
apto_ClinicalDevelopmentAndGlobalRegulatoryMilestoneFirstIndication
Represents the target clinical development and global regulatory milestones for the first indication.
AOCI Attributable to Parent [Member]
Accumulated Other Comprehensive Loss [Member]
January Two Thousand Twenty Four Investor Warrants [Member]
January two thousand twenty four investor warrants.
January 2024 Investor Warrants [Member]
Guaranteed Investment Certificate [Member]
Represents guaranteed investment certificate.
Warrants And Rights Outstanding Maturity Date One
Warrants and rights outstanding maturity date one.
Expiration date
Debt Instrument, Maturity Date
Repayment date
Minimum [Member]
Minimum [Member]
Weighted average grant date fair value, Granted
Weighted average grant date fair value, Granted
Weighted average grant date fair value, exercise price
Financial Instrument [Axis]
Current assets:
Assets, Current [Abstract]
Nasdaq Listing Rule Minimum Requirement For Stockholders Equity
Nasdaq listing rule minimum requirement for stockholders equity.
Nasdaq Listing Rule, minimum requirement for stockholders' equity
Capital Raise Amount
Capital raise amount.
Capital raise, amount
Level 3 [Member]
Level 3 [Member]
ESPP [Member]
Related to the ESPP.
Fair Value, Assets Measured on Recurring Basis [Table Text Block]
Assets Measured on a Recurring Basis
Assets Measured on a Recurring Basis
Current liabilities:
Liabilities, Current [Abstract]
Amended Facility Agreement [Member]
Amended facility agreement.
Related Party Transactions [Abstract]
Balance (in shares)
Balance (in shares)
Shares, Outstanding
Operating Loss Carryforwards, Total
Operating Loss Carryforwards
Tax Credit Carryforward [Table]
Restricted Cash Equivalent, Current
Restricted cash equivalents, current
Restricted cash and restricted cash equivalents
Commitments and Contingencies
Commitments and contingencies
Leases
Lessee, Leases [Policy Text Block]
General and Administrative Expense [Member]
Operating Lease, Liability
Lease liability, total
Present value of lease liabilities
Present value of lease liabilities
Total
Auditor Firm ID
Reverse stock split
Stockholders' Equity, Reverse Stock Split
Forecast [Member]
Scenario Forecast [Member]
Short-Term Debt
Short-Term Advance
Common Stock, No Par Value
Common Stock, No Par Value
Common shares, no par value
New Incentive Plan [Member]
New Incentive Plan [Member]
The 2022 atm offering.
The 2022 Atm Offering [Member]
The 2022 ATM Offering [Member]
Non-current liabilities:
Liabilities, Noncurrent [Abstract]
Effect of Exchange Rate on Cash, Cash Equivalent, Restricted Cash, and Restricted Cash Equivalent, Including Discontinued Operation
Effect of exchange rate fluctuations on cash and cash equivalents held
Effect of exchange rate fluctuations on cash and cash equivalents
Bank Time Deposits [Member]
High Interest Savings Accounts [Member]
High Interest Savings Accounts [Member]
Tax Credit Carryforward [Line Items]
Financing costs
Amount before allocation of valuation allowances of deferred tax asset attributable to deductible temporary differences from undeducted financing costs.
Financing costs
Cybersecurity Risk Management Positions or Committees Responsible [Text Block]
Weighted Average Number of Shares Outstanding, Basic, Total
Weighted Average Number of Shares Outstanding, Basic
Weighted average number of common shares outstanding used in the calculation of basic loss per share (in shares)
Weighted-average number of common shares outstanding, basic
Restrictions on Cash and Cash Equivalents [Table]
Scenario [Axis]
Stock and Warrants Issued During Period Shares
Stock and warrants issued during period shares.
Common shares and warrants issued under the November/January 2024 Public Offering (in shares)
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Intrinsic Value
Warrants And Rights Outstanding Maturity Date Two
Warrants and rights outstanding maturity date two.
Expiration date
Schedule of Effective Income Tax Rate Reconciliation
Schedule of Share-Based Compensation Arrangements by Share-Based Payment Award [Table]
Long-Lived Tangible Asset [Domain]
Cybersecurity Risk Process for Informing Management or Committees Responsible [Text Block]
Initial Commitment Shares [Member]
Initial Commitment Shares [Member]
Initial commitment shares.
Subsequent Events [Text Block]
Subsequent events
Related party transactions
Related Party Transactions Disclosure [Text Block]
Related party transactions
Cash, Ending Balance
Cash
APIC, Share-Based Payment Arrangement, Increase for Cost Recognition
APIC, Share-Based Payment Arrangement, Increase for Cost Recognition, Total
Stock-based compensation
Percentage of common shares outstanding.
Percentage of Common Shares Outstanding
Percentage of common shares outstanding.
Deferred Tax Asset, In-Process Research and Development
Research and development expenditures
Effective Income Tax Rate Reconciliation, Change in Deferred Tax Assets Valuation Allowance, Amount
Changes in valuation allowances
Positive shareholder's equity
Balance
Balance
Equity, Attributable to Parent
Negative shareholder's equity
Total shareholders' deficit
Basis of Accounting, Policy [Policy Text Block]
Basis of presentation - Going concern
Basis of presentation - going concern
Statement of Stockholders' Equity [Abstract]
Share-Based Payment Arrangement, Tranche Two [Member]
Use of Estimates, Policy [Policy Text Block]
Significant accounting policies, estimates and judgments
Equity Method Investment [Table]
Property, equipment, and other intangible assets
Amount before allocation of valuation allowances of deferred tax asset attributable to deductible temporary differences from property, plant, equipment, and other intangible assets.
Property, equipment, and other intangible assets
Over-Allotment Option [Member]
Over-Allotment Option [Member]
Leasehold Improvements [Member]
November Public Offering [Member]
November public offering.
November Public Offering [Member]
Entity Address, Address Line Two
Fair Value Disclosures [Text Block]
Fair value measurements and financial instruments
Debt Modification Description
Debt modification description.
Debt modification description
United States [Member]
UNITED STATES
Warrants and Rights Note Disclosure [Abstract]
March Five Two Thousand And Twenty Six [Member]
March five two thousand and twenty six.
March 5, 2026 [Member]
Schedule of Accrued Liabilities
Schedule of Accrued Liabilities [Table Text Block]
Other Assets, Current
Other current assets
Payment of supply costs
Payment Of Supply Costs
Payment of supply costs.
Prepaid research and development expenses
Amount of consideration paid in advance for research and development that provides economic benefits within a future period of one year or the normal operating cycle, if longer.
November Two Thousand And Twenty Four Public Offering [Member]
November 2024 Public Offering.
November 2024 Public Offering [Member]
Segment Reporting, CODM, Individual Title and Position or Group Name [Extensible Enumeration]
Hanmi Second Amended Facility Agreement [Member]
Hanmi second amended facility agreement .
Hanmi Second Amended Facility Agreement [Member]
Plan Name [Domain]
Computer Software [Member]
Software and Software Development Costs [Member]
Share-based Compensation Arrangement by Share-based Payment Award, Accelerated Vesting, Number (in shares)
Share-Based Compensation Arrangement by Share-Based Payment Award, Accelerated Vesting, Number
Other assets
Increase (Decrease) in Other Operating Assets
Increase (Decrease) in Other Operating Assets, Total
Other current assets
Interest Expense, Operating and Nonoperating
Interest Expense, Operating and Nonoperating, Total
Interest expense, related party
Interest expense, related party
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Entity [Domain]
Share Based Compensation Arrangement By Share Based Payment Award Non Option Equity Instruments Exercisable Weighted Average Remaining Contractual Life
Share based compensation arrangement by share based payment award non option equity instruments exercisable weighted average remaining contractual life.
Weighted average remaining contractual life, Exercisable (years)
Cybersecurity Risk Materially Affected or Reasonably Likely to Materially Affect Registrant [Text Block]
Schedule of Investments [Line Items]
Cybersecurity Risk Management Expertise of Management Responsible [Text Block]
Warrants outstanding
Class of Warrant or Right, Outstanding
Shares issuable upon exercise
Lessee, Operating Lease, Liability, to be Paid, Fiscal Year Maturity [Abstract]
Related and Nonrelated Parties [Axis]
Other
Effective Income Tax Rate Reconciliation, Other Adjustments, Amount
Class of Warrant or Right [Table]
Foreign Tax Jurisdiction [Member]
Reverse Stock Split [Policy Text Block]
Reverse Stock Split [Policy Text Block]
Reverse stock split
Property, Plant and Equipment, Policy [Policy Text Block]
Property and equipment
Right-of-use Assets Disclosure [Text Block]
The entire disclosure for right-of-use assets. This disclosure includes current assets and noncurrent assets.
Right-of-use assets, operating leases, net
Entity Address, City or Town
Cash, FDIC Insured Amount
FDIC insures deposits
Security Exchange Name
Prepaid Expense and Other Assets [Abstract]
Maximum amount available under single advance
Maximum Amount Available Under Single Advance
Maximum amount available under single advance.
Property, Plant and Equipment, Gross
Property, Plant and Equipment, Gross, Total
Property, Plant and Equipment, Gross, Beginning Balance
Property, Plant and Equipment, Gross, Ending Balance
Property, plant and equipment, gross
Employee Stock Purchase Plan, Maximum Payroll Deduction, Percent
apto_EmployeeStockPurchasePlanMaximumPayrollDeductionPercent
The percent maximum payroll deduction under an employee stock purchase plan.
Counterparty Name [Axis]
Share-based Compensation Arrangement by Share-based Payment Award, Options, Vested and Expected to Vest, Outstanding, Number (in shares)
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Outstanding, Number
Assets and Liabilities, Lessee [Abstract]
Share-Based Compensation Arrangement by Share-Based Payment Award, Non-Option Equity Instruments, Granted
Common shares issuable upon exercise, Issued
Measurement Input Type [Domain]
Antidilutive Securities, Name [Domain]
Vested Options [Member]
Information related to vested options.
Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Table]
Statistical Measurement [Domain]
Warrants to purchase common shares, exchange price
Class of Warrant or Right, Exercise Price of Warrants or Rights
Exercise price
Total current assets
Assets, Current
Share-based Payment Arrangement, Expense
Share-Based Payment Arrangement, Expense
Document Period End Date
Equity Method Investments and Joint Ventures [Abstract]
Title and Position [Axis]
Fair Value Hierarchy and NAV [Domain]
ICFR Auditor Attestation Flag
Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercisable, Number (in shares)
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Number
Gain (Loss) on Disposition of Property Plant Equipment, Total
Gain (Loss) on Disposition of Property Plant Equipment
Disposal of property and equipment
Loss on disposition of fixed assets
Loss on disposal of property and equipment
Statement of Financial Position [Abstract]
Restricted Stock Units (RSUs) [Member]
Restricted Stock Units (RSUs) [Member]
June 2024 Warrant [Member]
June Two Thousand And Twenty Four Warrant [Member]
June two thousand and twenty four warrant.
Two Thousand Twenty Five ATM Facility [Member]
Two Thousand Twenty Five ATM Facility [Member]
2025 ATM Facility
The 2025 ATM Offering [Member]
Amount received cash equal to shareholder
Amount received cash equal to shareholder
Antidilutive Security, Excluded EPS Calculation [Table]
Vesting [Axis]
Positive working capital
Working Capital
Working capital
Working capital.
Cybersecurity Risk Management, Strategy, and Governance [Line Items]
Warrants and Rights Outstanding, Maturity Date
Warrants, maturity date
Expiration date
Schedule Of Number Of Outstanding Warrants by exercise Price And Date Of Expirations
Schedule of number of outstanding warrants by exercise price and date of expirations.
Summary of Number of Outstanding Warrants by Exercise Price and Date of Expiration
Total liabilities
Liabilities
Financial Instruments [Domain]
The entire disclosure of the amounts paid in advance during the operating period.
Prepaid Expenses [Text Block]
Prepaid expenses
Registered Direct Offering [Member]
Registered direct offering.
Measurement Input, Exercise Price [Member]
Effective Income Tax Rate Reconciliation, Foreign Income Tax Rate Differential, Amount
Statutory tax rate difference between United States and Canada
Final advance received
Final Advance Received
Final advance received.
Restricted Cash and Cash Equivalent Item [Line Items]
Restricted Cash and Cash Equivalents Items [Line Items]
Restricted cash
Restricted Cash
Restricted Cash, Total
Weighted Average Number of Shares Outstanding, Diluted, Total
Weighted Average Number of Shares Outstanding, Diluted
Weighted average number of common shares outstanding used in the calculation of diluted loss per share (in shares)
Weighted-average number of common shares outstanding, diluted
Securities Act File Number
Initial proceeds from related party debt
Initial Proceeds from Related Party Debt
Initial proceeds from related party debt.
Options with Four Year Vesting [Member]
Information pertaining to options with four year vesting.
Cover [Abstract]
Measurement Input Type [Axis]
Cash and Cash Equivalents Disclosure [Text Block]
Cash and cash equivalents
Scenario [Domain]
U.S. Treasury Bills [Member]
United States Treasury Bills [Member]
Share-based Compensation Arrangement by Share-based Payment Award, Number of Shares Authorized (in shares)
Share-Based Compensation Arrangement by Share-Based Payment Award, Number of Shares Authorized
Share-based Compensation Arrangement by Share-based Payment Award, Number of Shares Authorized (in shares)
Number of Operating Segments
Number of operating segments
Sale of Stock [Domain]
General and Administrative Expense
General and Administrative Expense, Total
General and administrative
Property, Plant and Equipment, Useful Life [Table Text Block]
Tabular disclosure for the useful life of property, plant and equipment.
Summary of Property, Plant and Equipment Useful Life
Adjustment to Reconcile Net Income to Cash Provided by (Used in) Operating Activity, Noncash Item [Abstract]
Adjustments to reconcile net loss to cash used in operating activities:
Proceeds from Issuance of Common Stock, Gross
apto_ProceedsFromIssuanceOfCommonStockGross
The gross amount of cash inflow received from the issuance of common stock, before stock issuance costs.
Revenue from Contract with Customer, Including Assessed Tax
Revenue
Subsequent Event [Table]
First Back-End Commitment Shares [Member]
First Back-End Commitment Shares [Member]
First back-end commitment shares.
Laboratory Equipment [Member]
Related to laboratory equipment.
Cash Transaction Costs
Cash transaction costs.
Cash transaction costs
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Outstanding, Weighted Average Exercise Price
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Outstanding, Weighted Average Exercise Price
Property, plant and equipment, estimated useful lives
Estimated useful lives
Schedule of Investments [Table]
New Accounting Pronouncements, Policy [Policy Text Block]
Recent Accounting Pronouncements
Recent accounting pronouncements
Lessee, Operating Lease, Liability, to be Paid, Maturity [Table Text Block]
Summary of Minimum Payments, Undiscounted, Under Operating Leases
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]
Income (Loss) from Continuing Operations before Income Taxes, Domestic
Loss attributed to U.S. foreign operations
Clinical Development and Global Regulatory Milestone, Third Indication
apto_ClinicalDevelopmentAndGlobalRegulatoryMilestoneThirdIndication
Represents the target clinical development and global regulatory milestones for the third indication.
Depreciation of property and equipment
Depreciation
Depreciation, Total
Depreciation expense
Common Stock, Shares, Outstanding
Common Stock, Shares, Outstanding, Beginning Balance
Common Stock, Shares, Outstanding, Ending Balance
Common Stock, Shares Outstanding
Lease liability, current portion
Operating Lease, Liability, Current
Less: current portion of lease liability
Less: current portion of lease liability
Current portion of lease liability, operating leases
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Cybersecurity Risk Management Processes Integrated [Flag]
Stock and Warrants Issued During Period Value Registered Direct Offering
Stock and warrants issued during period value registered direct offering.
Shares and warrants issued pursuant to the June 2024 Registered Direct Offering
Document Transition Report
Operating Expenses
Total operating expenses
Accrued Liabilities, Current [Abstract]
Research and Development Expense
Research and Development Expense, Total
Research and development
The 2023 CMPO [Member]
The 2023 CMPO [Member]
The 2023 CMPO.
apto_OperatingLeaseRightOfUseAssetGross
Amount of lessee's right to use underlying asset under operating lease before amortization, depreciation, and depletion.
Right-of-use assets, operating leases, beginning of year
Right-of-use assets, operating leases, end of year
Common shares issued (in shares)
Stock Issued During Period, Shares, Licensing Fees (in shares)
Common shares issued pursuant to the Hanmi licensing fees (in shares)
Shares of stock issued for licensing fees.
Schedule of Investments [Abstract]
Statement of Cash Flows [Abstract]
Alliance Global Partners [Member]
Alliance Global Partners.
Alliance Global Partners [Member]
Common shares issued
Common shares issued under the 2023 Committed Equity Facility/2022 ATM Facility/2025 ATM Facility
Cash proceeds from issuing shares
Share-Based Payment Arrangement, Option, Activity [Table Text Block]
Share-based Payment Arrangement, Option, Activity
Equity [Text Block]
Share capital
Two Thousand And Twenty One Stock Incentive Plan [Member]
Two thousand and twenty one stock incentive plan.
2021 Plan [Member]
Measurement Input, Expected Dividend Rate [Member]
Share-based Payment Arrangement, Vesting and Redemption of the RSUs Granted
Share-Based Payment Arrangement, Restricted Stock Unit, Activity [Table Text Block]
Computer Equipment [Member]
Computer Hardware [Member]
Cybersecurity Risk Management Processes Integrated [Text Block]
Investment [Table Text Block]
Summary of Investments
Net loss
Net loss and comprehensive loss
Net loss and comprehensive loss
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Intrinsic Value
Operating Lease, Cost
Operating lease cost
Warrants and Rights Outstanding, Term
Warrants, Remaining contractual life
Warrants expiration period
Accrued research and development expenses
The amount of research and development liabilities classified as current.
Accrued research and development expenses
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Dividend Rate
Expected dividend yield
Premium share price (as a percent)
Premium Share Price Percent
Premium share price percent.
June 2024 Pre-funded Warrants [Member]
June 2024 Pre-funded Warrants.
Operating lease payments
Operating cash flows from operating leases
Total minimum lease payments
Cash flows from operating leases
Lease payment per month
Income Tax Authority, Name [Axis]
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Risk Free Interest Rate
Risk-free interest rate
HCW Warrants [Member]
HCW warrants.
Document Fiscal Year Focus
Debt Conversion, Converted Instrument, Shares Issued
Common shares converted
Share Based Compensation Arrangement By Share Based Payment Award Non Option Equity Instruments Exercisable Number
Share based compensation arrangement by share based payment award non option equity instruments exercisable number.
Common shares issuable upon exercise, Exercisable
Class Of Warrant Or Right Outstanding Two
Class of warrant or right outstanding two.
Shares issuable upon exercise
Cash Provided by (Used in) Investing Activity, Including Discontinued Operation [Abstract]
Cash flows from investing activities:
Accounts payable
Accounts payable to related party
Accounts Payable, Current
Accounts Payable, Current, Total
Keystone [Member]
Keystone [Member]
Keystone.
Interest Expense, Long-Term Debt
Interest Expense, Long-Term Debt, Total
Interest on loan paid
Interest expense
Schedule of Loss before Income Taxes, Domestic and Foreign
Research and Development Expense [Member]
Total
Accrued Liabilities Current Net
Accrued liabilities current net.
Short-Term Advance from CEO [Member]
Short-term advance from CEO.
Deferred Costs, Capitalized, Prepaid, and Other Assets Disclosure [Table Text Block]
Summary of Prepaid Expenses and Other Assets
Research Tax Credit Carryforward [Member]
Fair Value Measurement, Policy [Policy Text Block]
Fair value
Convertible Debt
Convertible Debt, Total
Convertiable debt amount
Accounting Policy [Table]
Accounting policy.
November Twenty Five Two Thousand Twenty Nine [Member]
November twenty five two thousand twenty nine.
November 25, 2029 [Member]
Fair Value Disclosures [Abstract]
Commitments and Contingencies Disclosure [Abstract]
Measurement Input, Share Price [Member]
2025
Lessee, Operating Lease, Liability, to be Paid, Year One
2026
Loan payable to related parties, Non-current
Loan payable to related parties, non-current.
Loan payable to related party
License Fee, Total
apto_LicenseFeeTotal
Represents total license fee.
Change in fair value of warrants
Change In Fair Value Of Warrant Liability
Change in fair value of warrant liability.
Effective Income Tax Rate Reconciliation [Line Items]
Interest Expenses Related Party
Interest expenses related party.
Interest expense, related party
Interest expense, related party
Derivative Instrument [Axis]
Share-Based Payment Arrangement [Abstract]
Common shares issued pursuant to Hanmi debt conversion (in shares)
Stock Issued During Period Shares Debt Conversion
Stock issued during period shares debt conversion.
Assets, Fair Value Disclosure
Assets, Fair Value Disclosure, Total
Assets, Fair Value Disclosure
Sale of Stock [Axis]
Schedule of Share-based Payment Award, Options, Grants in Period [Table Text Block]
Tabular disclosure of share options granted during the period.
Schedule of Share-based Payment Award, Options, Grants in Period
Cash Provided by (Used in) Investing Activity, Including Discontinued Operation
Cash provided by investing activities
Private Placement [Member]
Private Placement [Member]
Commitment Shares [Member]
Commitment Shares [Member]
Commitment shares.
Property, Plant and Equipment, Additions
Additions to fixed assets
Title of 12(b) Security
Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Forfeitures in Period, Weighted Average Exercise Price
Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Forfeitures in Period, Weighted Average Exercise Price
Outstanding, weighted average exercise price (in dollars per share)
Weighted average exercise price, Forfeited/expired
Money Market Funds [Member]
Related and Nonrelated Parties [Domain]
Income Tax Disclosure
Income taxes
Basis Of Presentation Functional Currency Presentation Currency And Consolidation [Policy Text Block]
Basis of presentation functional currency presentation currency and consolidation.
Basis of presentation - functional currency, presentation currency and consolidation
January Two Thousand And Twenty Four Public Offering [Member]
January two thousand and twenty four public offering.
January 2024 Public Offering [Member]
Collaborative Arrangement and Arrangement Other than Collaborative [Table]
Class of Warrant or Right [Line Items]
Stock Issuance, Percent of Cash Commission to Broker
apto_StockIssuancePercentOfCashCommissionToBroker
The percent of cash commission payable to the broker of a stock issuance.
Legal Entity [Axis]
cash flows pursuant to the revised
cash flows pursuant to the revised
Adjustment to Reconcile Net Income to Cash Provided by (Used in) Operating Activity, Increase (Decrease) in Operating Capital [Abstract]
Change in operating assets and liabilities:
Notes To Financial Statements Abstract
Notes To Financial Statements [Abstract]
Property, Plant and Equipment [Table Text Block]
Schedule of Property and Equipment
Stock Issuance Program, Authorized Amount
apto_StockIssuanceProgramAuthorizedAmount
Amount of stock issuance plan authorized.
Outstanding, weighted average exercise price (in dollars per share)
Outstanding, weighted average exercise price (in dollars per share)
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Exercise Price
Hanmi [Member]
Hanmi [Member]
Hanmi.
Fair Value, Recurring and Nonrecurring [Table]
Restricted Cash Equivalents Disclosure [Text Block]
Restricted cash equivalents disclosure.
Restricted Cash and Restricted Cash Equivalents
Additional Paid-in Capital [Member]
Additional Paid-in Capital [Member]
Statement of Income Location, Balance [Axis]
Trading Symbol
Property, Plant and Equipment Disclosure [Text Block]
Property and equipment
Stock and Warrants Issued During Period Value Subscription Agreement1
Stock and warrants issued during period value subscription agreement1.
Common shares and warrants under the Registered Direct Offering/ issued pursuant to the Hanmi Private Placement
Lessee, Operating Lease Liability and Weighted Average [Table Text Block]
Tabular disclosure of lessee's operating lease liability and weighted average of operating lease liability.
Summary of Weighted Average Remaining Term of Leases and Weighted Average Discount Rate
Summary of Information Related to Company's leases
CrystalGenomics, Inc. [Member]
CrystalGenomics, Inc. [Member]
CrystalGenomics, Inc.
Subsequent Event Type [Axis]
Supply Agreement [Member]
Supply Agreement [Member]
Supply agreement.
Employee-related Liabilities, Current
Employee-related Liabilities, Current, Total
Accrued personnel related costs
Cash flows from financing activities:
Cash Provided by (Used in) Financing Activity, Including Discontinued Operation [Abstract]
Annual Escalation Rate
Annual escalation rate.
Annual escalation rate
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Term
Expected life of options (years)
Expected life (years)
Accounts Payable and Accrued Liabilities Disclosure [Text Block]
Accrued liabilities
Future milestone payments
Future Milestone Payments
Future milestone payments.
Schedule of Equity Method Investments [Line Items]
Lessee, Operating Lease, Liability, to be Paid
Total minimum lease payments
Lessee, Operating Lease, Liability, Undiscounted Excess Amount
Less: imputed interest
apto_AmortizationOfRightofUseAssets
The aggregate amount of recurring noncash expense charged against earnings in the period to allocate the cost of right-of-use assets over their estimated remaining economic lives.
Less: accumulated amortization
Canadian Treasury Securities [Member]
This category includes information about debt securities issued by the Canadian Department of the Treasury and backed by the Canadian government. Such securities primarily consist of treasury bills (short-term maturities - one year or less), treasury notes (intermediate term maturities - two to ten years), and treasury bonds (long-term maturities - ten to thirty years).
Government of Canada Treasury Bill [Member]
Stock and Warrants Issued During Period Shares Registered Direct Offering
Stock and warrants issued during period shares registered direct offering.
Shares and warrants issued pursuant to the June 2024 Registered Direct Offering (in shares)
Equity Components [Axis]
Share-based Compensation Arrangement by Share-based Payment Award, Options, Vested and Expected to Vest, Exercisable, Weighted Average Remaining Contractual Term (Month)
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Exercisable, Weighted Average Remaining Contractual Term
Second Tranche [Member]
Equity Method Investment Second Tranche [Member]
Equity method investment second tranche.
Nonoperating Income (Expense)
Total other (expenses) income
Equity Component [Domain]
Asset Class [Axis]
June 2024 Registered Direct Offering [Member]
June 2024 Registered Direct Offering.
June 2024 Registered Direct Offering [Member]
Warrants, issued
Class of Warrant or Right, Issued
Class of warrant or right, issued.
Document Annual Report
Prepaid Insurance
Prepaid insurance
The 2025 A T M Offering [Member]
The 2025 ATM Offering.
The 2025 ATM Offering [Member]
Stock Issued During Period, Shares, Restricted Stock Award, Net of Forfeitures, Total (in shares)
Stock Issued During Period, Shares, Restricted Stock Award, Net of Forfeitures
Stock Issued During Period, Shares, Restricted Stock Award, Net of Forfeitures, Total
Common shares issued upon redemption of restricted share units, shares
Stock Issued During Period, Shares, Employee Stock Purchase Plans
Common shares issued under the ESPP plan (Shares)
Common shares issued under the ESPP (Shares)
Share-based Compensation Arrangement by Share-based Payment Award, Expiration Period (Year)
Share-Based Compensation Arrangement by Share-Based Payment Award, Expiration Period
Interest On Loan Payable To Related Party
Interest on loan payable to related party.
Interest on loan payable to related party
Commercial Notes [Member]
Represents commercial notes.
Maximum [Member]
Maximum [Member]
Liabilities, Fair Value Disclosure
Liabilities, Fair Value Disclosure, Total
Statistical Measurement [Axis]
Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Exercises in Period, Weighted Average Exercise Price
Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Exercises in Period, Weighted Average Exercise Price
Prepaid Expense, Current
Prepaid expenses
Total
Common Stock, Value, Issued
Common shares, no par value, unlimited authorized shares, 2,552,429 and 2,006,028 shares issued and outstanding as of December 31, 2025 and December 31, 2024, respectively
Shareholders voting percentage required for arrangement
Shareholders Voting Percentage Required For Arrangement
Shareholders voting percentage required for arrangement.
Cash and Cash Equivalents [Abstract]
Consolidation, Policy [Policy Text Block]
Basis of consolidation
Loan Payable to Related Party [Member]
Loan payable to related party.
Warrants [Policy Text Block]
Warrants.
Warrants
Deferred Tax Assets, Operating Loss Carryforwards
Deferred Tax Assets, Operating Loss Carryforwards, Total
Net operating losses carried forward
Cybersecurity Risk Management Processes for Assessing, Identifying, and Managing Threats [Text Block]
Tax Credit Carryforward [Axis]
Share-Based Compensation Arrangement by Share-Based Payment Award, Non-Option Equity Instruments, Exercised
Common shares issuable upon exercise, Exercised
Common shares issuable upon exercise, Exercised
Deferred Tax Assets Restricted Interest And Financing Expenses
Deferred tax assets restricted interest and financing expenses.
Restricted interest and financing expenses
Entity Public Float
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Volatility Rate
Expected volatility
Interest Payable, Current
Accrued interest on the unpaid principal loan
Entity Registrant Name
Entity Voluntary Filers
Lessee Disclosure [Abstract]
Additional Paid in Capital
Additional Paid in Capital, Total
Additional paid-in capital
Interest on Related Party Loan Payable, Noncurrent
Interest on related party loan payable.
Interest on related party loan payable
January Two Thousand And Twenty Four Hanmi Private Placement [Member]
January two thousand and twenty four hanmi private placement.
January 2024 Hanmi Private Placement [Member]
Subsequent Events [Abstract]
Other Assets Disclosure [Text Block]
Other Long-Term Assets
Global Sales Milestone
apto_GlobalSalesMilestone
Represents the target global sales milestone.
Unvested Options [Member]
Information related to unvested options.
Cybersecurity Risk Management Positions or Committees Responsible [Flag]
Income Tax Expense (Benefit)
Tax rate reconciliation
Proceeds from Issuance of Common Stock
Issuance of common shares
Issuance of common shares under the ESPP share purchase
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]
Entity Common Stock, Shares Outstanding
Concentration Risk, Credit Risk, Policy [Policy Text Block]
Concentration of risk
Lessee, Operating Lease, Remaining Lease Term
Lease term
Proceeds From Issuance Of Common Stock and Warrants
Proceeds from issuance of common stock and warrants.
Issuance of common shares and warrants
Hanmi Warrants [Member]
Hanmi warrants.
Hanmi Warrants [Member]
Accumulated Other Comprehensive Income (Loss), Net of Tax
Accumulated Other Comprehensive Income (Loss), Net of Tax, Total
Accumulated other comprehensive loss
Payments to Acquire Property, Plant, and Equipment
Payments to Acquire Property, Plant, and Equipment, Total
Purchase of property and equipment
Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Grants in Period (in shares)
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Grants in Period
Number , Granted
January Thirty Two Thousand And Twenty Eight [Member]
January thirty two thousand and twenty eight.
January 30, 2028 [Member]
Total assets
Assets
Property, Plant and Equipment [Table]
Payments for (Proceeds from) Investments
Payments for (Proceeds from) Investments, Total
(Acquisition) maturity of investments, net
Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercisable, Weighted Average Remaining Contractual Term (Month)
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Weighted Average Remaining Contractual Term
Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercisable, Weighted Average Remaining Contractual Term (Month)
Income Statement [Abstract]
Right-of-use assets
Amount before allocation of valuation allowances of deferred tax asset attributable to deductible temporary differences from right-of-use assets.
Right-of-use assets
2023 Committed Equity Facility [Member]
2023 Committed Equity Facility [Member]
2023 committed equity facility.
Share-Based Payment Arrangement [Policy Text Block]
Stock-based compensation
Pre Funded Warrants [Member]
Pre-funded warrants.
Exercised during 2024, Pre-Funded Warrant [Member]
Pre-Funded Warrants [Member]
Number of shares sold
Sale of Stock, Number of Shares Issued in Transaction
Payments for License Fee
apto_PaymentsForLicenseFee
Represents cash outflow for license fee.
Common shares issued (in shares)
Stock Issued During Period, Shares, New Issues (in shares)
Common shares issued under the 2023 Committed Equity Facility/2022 ATM Facility/2025 ATM Facility (in shares)
Lease, Cost [Abstract]
Earnings Per Share, Diluted, Total
Earnings Per Share, Diluted
Net loss per common share, diluted
Net loss per common share, diluted
Convertible debt conversion
Debt Conversion, Original Debt, Amount
Title and Position [Domain]
City Area Code
November Two Thousand Twenty Four Public Offering [Member]
November 2024 public offering.
November 2024 Public Offering [Member]
Auditor Name
Restricted Cash and Cash Equivalent, Current
Restricted Cash and Cash Equivalent, Current, Total
Restricted cash and restricted cash equivalents
Tuspetinib Licensing Agreement [Member]
Tuspetinib Licensing Agreement [Member]
Tuspetinib Licensing Agreement.
Loan agreement amount
Debt Instrument, Face Amount
Additional Proceeds from Related Party Debt
Additional proceeds from related party debt.
Additional proceeds from related party debt
Options with Cliff Vesting After One Year Anniversary [Member]
Information pertaining to options with cliff vesting after one year anniversary.
Counterparty Name [Domain]
Stock Issued During Period, Value, Employee Stock Purchase Plan
Common shares issued under the ESPP
Operating Lease, Weighted Average Remaining Lease Term
Weighted-average remaining term - operating leases (years)
Investments [Abstract]
Exclusive License to CG806 in China, Development Milestones [Member]
Related to agreement development milestones.
Cash and Cash Equivalents, Policy [Policy Text Block]
Cash and cash equivalents
Property, Plant and Equipment, Net
Property, plant and equipment, net
Property and equipment, net
Property and equipment, net
Officer [Member]
Common shares and warrants issued in S-1 financing (in shares)
Common Shares and Warrants Issued In S1 Financing
Common shares and warrants issued in s1 financing.
Cash, Cash Equivalent, Restricted Cash, and Restricted Cash Equivalent, Including Discontinued Operation
Cash, Cash Equivalents, Restricted Cash, and Restricted Cash Equivalents, Including Disposal Group and Discontinued Operations, Total
Total cash, cash equivalents, and restricted cash equivalents shown in the consolidated statements of cash flows
Cash, cash equivalents, restricted cash and restricted cash equivalents, beginning of year
Cash, cash equivalents, restricted cash and restricted cash equivalents, end of the year
Total cash, cash equivalents, restricted cash and restricted cash equivalents shown in the consolidated statements of cash flow
Retained Earnings [Member]
Accumulated Deficit [Member]
Total non-current assets
Assets, Noncurrent
Stock-based compensation
Share-Based Payment Arrangement, Noncash Expense
Share-Based Payment Arrangement, Noncash Expense, Total
Measurement Input, Price Volatility [Member]
Liabilities, Noncurrent
Total non-current liabilities
Operating Lease, Weighted Average Discount Rate, Percent
Weighted-average discount rate - operating leases
Operating Lease, Liability, Noncurrent
Lease liability, operating leases
Lease liability, non-current
Lease liability, non-current
Level 1 [Member]
Level 1 [Member]
Class of Stock [Line Items]
Notes to Financial Statements
Disclosure Text Block [Abstract]
Notes to Financial Statements
Cash provided by financing activities
Cash Provided by (Used in) Financing Activity, Including Discontinued Operation
Lease, Cost [Table Text Block]
Summary of Operating Lease Costs and Operating Lease Cash Flows
Auditor Location
November Two Thousand Twenty Four Investor Warrants [Member]
November Two Thousand Twenty Four Investor Warrants.
November 2024 Investor Warrants [Member]
Debt Conversion Agreement [Member]
Debt conversion agreement.
Debt Conversion Agreement
Schedule of Stockholders' Equity Note, Warrants or Rights [Table Text Block]
Summary of Warrant Activity
Nonoperating Income (Expense) [Abstract]
Other income (expenses):
Derivative Contract [Domain]
Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table Text Block]
Schedule of Total Anti-dilutive Shares
Pre-Funded Warrants exercised
Pre-Funded warrants exercised.
Pre-Funded warrants exercised
Corporate Debt Securities [Member]
Guaranteed Investment Certificate [Member]
Income Tax Jurisdiction [Domain]
Placement Agent Fees
Placement agent fees.
Placement agent fees
Entity Interactive Data Current
June three two thousand and twenty nine [Member]
June three two thousand and twenty nine.
June 3, 2029 [Member]
Collaborative Agreements [Text Block]
Disclosure for collaborative agreements.
Collaborative agreements
Statement of Income Location, Balance [Domain]
Costs and Expenses, Related Party
Expenses
Cash flows from operating activities:
Cash Provided by (Used in) Operating Activity, Including Discontinued Operation [Abstract]
Furniture and Fixtures [Member]
Office Furniture [Member]
Proceeds from Related Party Debt
Proceeds from loan payable with related parties
Proceeds from loans payable with related parties
Debt Instrument, Periodic Payment, Interest
Interest expense paid
Cash Equivalents, at Carrying Value
Cash Equivalents, at Carrying Value, Total
Cash and cash equivalents
Cash and cash equivalents
Entity Tax Identification Number
Share Price
Issue date fair value (per equivalent share)
Reporting entity
Organization, Consolidation and Presentation of Financial Statements Disclosure [Text Block]
Income Tax Authority, Name [Domain]
Local Phone Number
Related Party Transaction [Domain]
Future expense associated with option
Share-based Payment Arrangement, Nonvested Award, Option, Cost Not yet Recognized, Amount
Share-Based Payment Arrangement, Nonvested Award, Option, Cost Not yet Recognized, Amount
Auditor Opinion [Text Block]
Share-Based Compensation Arrangement by Share-Based Payment Award, Non-Option Equity Instruments, Forfeitures
Common shares issuable upon exercise, Forfeited/expired
Fixed assets original cost.
Fixed Assets Original Cost
Fixed assets original cost
Class Of Warrant Or Right Exercise Price Of Warrants Or Rights Three
Class of warrant or right exercise price of warrants or rights three.
Exercise price
Exercise price
Accounting Policies [Abstract]
Financing costs including underwriting costs, professional fees and recognition of deferred financing costs
Financing Costs Including Underwriting Costs, Professional Fees and Recognition of Deferred Financing Costs
Financing costs including underwriting costs, professional fees and recognition of deferred financing costs.
Debt conversion, description
Debt Conversion, Description
Share-based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Period for Recognition (Year)
Share-Based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Period for Recognition
Total Advances
Total advances.
Total advances
Cash, Cash Equivalents, and Short-Term Investments, Total
Cash, Cash Equivalents, and Short-Term Investments
Cash and investment
Stock, Class of Stock [Table]
Hanmi Private Placement [Member]
Hanmi private placement.
Hanmi Private Placement [Member]
Common Stock, Shares Authorized, Unlimited [Fixed List]
Common Stock, Shares Authorized
Negative working capital
Negative Working Capital
Negative working capital.
Entity Emerging Growth Company
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Outstanding, Weighted Average Remaining Contractual Term
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Outstanding, Weighted Average Remaining Contractual Term
Tax Credit Carryforward, Name [Domain]