v3.26.1
Consolidated Statements of Shareholders' Equity - USD ($)
$ in Thousands
Total
Underwriter Offering
ATM Program
Ordinary shares
Ordinary shares
Underwriter Offering
Ordinary shares
ATM Program
Additional paid-in capital
Additional paid-in capital
Underwriter Offering
Additional paid-in capital
ATM Program
Accumulated other comprehensive income
Accumulated deficit
Beginning balance (in shares) at Dec. 31, 2023       98,774,827              
Beginning balance at Dec. 31, 2023 $ 236,244     $ 273     $ 987,423     $ 1,493 $ (752,945)
Increase (Decrease) in Stockholders' Equity [Roll Forward]                      
Issuance of ordinary shares, net of issuance costs (in shares)         29,932,626 1,250,000          
Issuance of ordinary shares, net of issuance costs   $ 349,950 $ 9,655   $ 76 $ 3   $ 349,874 $ 9,652    
Stock option exercises (in shares)       1,853,718              
Stock option exercises 11,263     $ 4     11,259        
Share-based compensation expense 33,546           33,546        
Vesting of ordinary shares (in shares)       1,328,991              
Vesting of ordinary shares 0     $ 3     (3)        
Shares withheld to pay employee withholding tax on equity awards (in shares)       (508,575)              
Shares withheld to pay employee withholding tax on equity awards (6,076)           (6,076)        
Foreign currency translation adjustments 1,223                 1,223  
Unrealized gain on available for sale securities, net of tax 2,787                 2,787  
Reclassification adjustment for realized net gain on available for sale marketable securities included in net loss, net of tax (1,290)                 (1,290)  
Net loss $ (235,757)                   (235,757)
Ending balance (in shares) at Dec. 31, 2024 132,631,587     132,631,587              
Ending balance at Dec. 31, 2024 $ 401,545     $ 359     1,385,675     4,213 (988,702)
Increase (Decrease) in Stockholders' Equity [Roll Forward]                      
Issuance of ordinary shares, net of issuance costs (in shares)         13,372,093 372,538          
Issuance of ordinary shares, net of issuance costs   $ 269,249 $ 6,109   $ 36 $ 1   $ 269,213 $ 6,108    
Stock option exercises (in shares) 2,505,396     2,505,396              
Stock option exercises $ 21,326     $ 8     21,318        
Share-based compensation expense 30,962           30,962        
Vesting of ordinary shares (in shares)       540,824              
Vesting of ordinary shares 0     $ 1     (1)        
Shares withheld to pay employee withholding tax on equity awards (in shares)       (194,370)              
Shares withheld to pay employee withholding tax on equity awards (3,297)           (3,297)        
Foreign currency translation adjustments 1,045                 1,045  
Unrealized gain on available for sale securities, net of tax 243                 243  
Reclassification adjustment for realized net gain on available for sale marketable securities included in net loss, net of tax (2,787)                 (2,787)  
Net loss $ (197,532)                   (197,532)
Ending balance (in shares) at Dec. 31, 2025 149,228,068     149,228,068              
Ending balance at Dec. 31, 2025 $ 526,863     $ 405     $ 1,709,978     $ 2,714 $ (1,186,234)