000 - Document - Document And Entity Information link:calculationLink link:definitionLink link:presentationLink 001 - Statement - Consolidated Balance Sheets link:calculationLink link:definitionLink link:presentationLink 002 - Statement - Consolidated Balance Sheets (Parentheticals) link:calculationLink link:definitionLink link:presentationLink 003 - Statement - Consolidated Statements of Operations link:calculationLink link:definitionLink link:presentationLink 004 - Statement - Consolidated Statements of Stockholders' Equity link:calculationLink link:definitionLink link:presentationLink 005 - Statement - Consolidated Statements of Cash Flows link:calculationLink link:definitionLink link:presentationLink 995554 - Disclosure - Note 1 - Organization and Nature of Operations link:calculationLink link:definitionLink link:presentationLink 995555 - Disclosure - Note 2 - Summary of Significant Accounting Policies link:calculationLink link:definitionLink link:presentationLink 995556 - Disclosure - Note 3 - Inventories link:calculationLink link:definitionLink link:presentationLink 995557 - Disclosure - Note 4 - Property and Equipment link:calculationLink link:definitionLink link:presentationLink 995558 - Disclosure - Note 5 - Intangible Assets link:calculationLink link:definitionLink link:presentationLink 995559 - Disclosure - Note 6 - Accrued Expenses link:calculationLink link:definitionLink link:presentationLink 995560 - Disclosure - Note 7 - Notes Payable link:calculationLink link:definitionLink link:presentationLink 995561 - Disclosure - Note 8 - Royalties Payable link:calculationLink link:definitionLink link:presentationLink 995562 - Disclosure - Note 9 - Leases link:calculationLink link:definitionLink link:presentationLink 995563 - Disclosure - Note 10 - Net Loss Per Share link:calculationLink link:definitionLink link:presentationLink 995564 - Disclosure - Note 11 - Equity Offerings link:calculationLink link:definitionLink link:presentationLink 995565 - Disclosure - Note 12 - Preferred Stock link:calculationLink link:definitionLink link:presentationLink 995566 - Disclosure - Note 13 - Stock-based Compensation link:calculationLink link:definitionLink link:presentationLink 995567 - Disclosure - Note 14 - Asset Acquisitions link:calculationLink link:definitionLink link:presentationLink 995568 - Disclosure - Note 15 - Income Taxes link:calculationLink link:definitionLink link:presentationLink 995569 - Disclosure - Note 16 - Commitments and Contingencies link:calculationLink link:definitionLink link:presentationLink 995570 - Disclosure - Note 17 - Related Parties link:calculationLink link:definitionLink link:presentationLink 995571 - Disclosure - Note 18 - Subsequent Events link:calculationLink link:definitionLink link:presentationLink 995572 - Disclosure - Significant Accounting Policies (Policies) link:calculationLink link:definitionLink link:presentationLink 995573 - Disclosure - Note 2 - Summary of Significant Accounting Policies (Tables) link:calculationLink link:definitionLink link:presentationLink 995574 - Disclosure - Note 3 - Inventories (Tables) link:calculationLink link:definitionLink link:presentationLink 995575 - Disclosure - Note 4 - Property and Equipment (Tables) link:calculationLink link:definitionLink link:presentationLink 995576 - Disclosure - Note 5 - Intangible Assets (Tables) link:calculationLink link:definitionLink link:presentationLink 995577 - Disclosure - Note 6 - Accrued Expenses (Tables) link:calculationLink link:definitionLink link:presentationLink 995578 - Disclosure - Note 7 - Notes Payable (Tables) link:calculationLink link:definitionLink link:presentationLink 995579 - Disclosure - Note 8 - Royalties Payable (Tables) link:calculationLink link:definitionLink link:presentationLink 995580 - Disclosure - Note 9 - Leases (Tables) link:calculationLink link:definitionLink link:presentationLink 995581 - Disclosure - Note 10 - Net Loss Per Share (Tables) link:calculationLink link:definitionLink link:presentationLink 995582 - Disclosure - Note 11 - Equity Offerings (Tables) link:calculationLink link:definitionLink link:presentationLink 995583 - Disclosure - Note 12 - Preferred Stock (Tables) link:calculationLink link:definitionLink link:presentationLink 995584 - Disclosure - Note 13 - Stock-based Compensation (Tables) link:calculationLink link:definitionLink link:presentationLink 995585 - Disclosure - Note 15 - Income Taxes (Tables) link:calculationLink link:definitionLink link:presentationLink 995586 - Disclosure - Note 17 - Related Parties (Tables) link:calculationLink link:definitionLink link:presentationLink 995587 - Disclosure - Note 1 - Organization and Nature of Operations (Details Textual) link:calculationLink link:definitionLink link:presentationLink 995588 - Disclosure - Note 2 - Summary of Significant Accounting Policies (Details Textual) link:calculationLink link:definitionLink link:presentationLink 995589 - Disclosure - Note 2 - Summary of Significant Accounting Policies - Segment Reporting (Details) link:calculationLink link:definitionLink link:presentationLink 995590 - Disclosure - Note 2 - Summary of Significant Accounting Policies - Fair Value Measurements (Details) link:calculationLink link:definitionLink link:presentationLink 995591 - Disclosure - Note 2 - Summary of Significant Accounting Policies - Unobservable Inputs (Details) link:calculationLink link:definitionLink link:presentationLink 995592 - Disclosure - Note 2 - Summary of Significant Accounting Policies - Reconciliation of Level 3 Assets and Liabilities (Details) link:calculationLink link:definitionLink link:presentationLink 995593 - Disclosure - Note 2 - Summary of Significant Accounting Policies - Nonrecurring Fair Value Measurements (Details) link:calculationLink link:definitionLink link:presentationLink 995594 - Disclosure - Note 2 - Summary of Significant Accounting Policies - Useful Life of Property and Equipment (Details) link:calculationLink link:definitionLink link:presentationLink 995595 - Disclosure - Note 2 - Summary of Significant Accounting Policies - Disaggregation of Revenue (Details) link:calculationLink link:definitionLink link:presentationLink 995596 - Disclosure - Note 3 - Inventories (Details Textual) link:calculationLink link:definitionLink link:presentationLink 995597 - Disclosure - Note 3 - Inventories - Schedule of Inventories (Details) link:calculationLink link:definitionLink link:presentationLink 995598 - Disclosure - Note 4 - Property and Equipment (Details Textual) link:calculationLink link:definitionLink link:presentationLink 995599 - Disclosure - Note 4 - Property and Equipment - Schedule of Property and Equipment, Net (Details) link:calculationLink link:definitionLink link:presentationLink 995600 - Disclosure - Note 5 - Intangible Assets (Details Textual) link:calculationLink link:definitionLink link:presentationLink 995601 - Disclosure - Note 5 - Intangible Assets - Summary of Intangible Assets (Details) link:calculationLink link:definitionLink link:presentationLink 995602 - Disclosure - Note 5 - Intangible Assets - Estimated Future Amortization Expense (Details) link:calculationLink link:definitionLink link:presentationLink 995603 - Disclosure - Note 6 - Accrued Expenses - Schedule of Accrued Expenses (Details) link:calculationLink link:definitionLink link:presentationLink 995604 - Disclosure - Note 7 - Notes Payable (Details Textual) link:calculationLink link:definitionLink link:presentationLink 995605 - Disclosure - Note 7 - Notes Payable - Future Maturities for Long-term Debt (Details) link:calculationLink link:definitionLink link:presentationLink 995606 - Disclosure - Note 8 - Royalties Payable (Details Textual) link:calculationLink link:definitionLink link:presentationLink 995607 - Disclosure - Note 8 - Royalties Payable - Sales-based Royalties (Details) link:calculationLink link:definitionLink link:presentationLink 995608 - Disclosure - Note 9 - Leases (Details Textual) link:calculationLink link:definitionLink link:presentationLink 995609 - Disclosure - Note 9 - Leases - Supplemental Information (Details) link:calculationLink link:definitionLink link:presentationLink 995610 - Disclosure - Note 9 - Leases - Lease Terms and Discount Rate (Details) link:calculationLink link:definitionLink link:presentationLink 995611 - Disclosure - Note 9 - Leases - Future Lease Payments (Details) link:calculationLink link:definitionLink link:presentationLink 995612 - Disclosure - Note 9 - Leases - Lease Right-of-use Assets and Lease Liabilities (Details) link:calculationLink link:definitionLink link:presentationLink 995613 - Disclosure - Note 10 - Net Loss Per Share (Details Textual) link:calculationLink link:definitionLink link:presentationLink 995614 - Disclosure - Note 10 - Net Loss per Share - Antidilutive Securities (Details) link:calculationLink link:definitionLink link:presentationLink 995615 - Disclosure - Note 11 - Equity Offerings (Details Textual) link:calculationLink link:definitionLink link:presentationLink 995616 - Disclosure - Note 11 - Equity Offerings - Schedule of Warrants or Rights (Details) link:calculationLink link:definitionLink link:presentationLink 995617 - Disclosure - Note 11 - Equity Offerings - Issuance of Warrants (Details) link:calculationLink link:definitionLink link:presentationLink 995618 - Disclosure - Note 12 - Preferred Stock (Details Textual) link:calculationLink link:definitionLink link:presentationLink 995619 - Disclosure - Note 12 - Preferred Stock - Schedule of Conversions (Details) link:calculationLink link:definitionLink link:presentationLink 995620 - Disclosure - Note 13 - Stock-based Compensation (Details Textual) link:calculationLink link:definitionLink link:presentationLink 995621 - Disclosure - Note 13 - Stock-based Compensation - Assumptions (Details) link:calculationLink link:definitionLink link:presentationLink 995622 - Disclosure - Note 13 - Stock-based Compensation - Schedule of Stock Option Activity (Details) link:calculationLink link:definitionLink link:presentationLink 995623 - Disclosure - Note 13 - Stock-based Compensation - Schedule of Restricted Stock Activity (Details) link:calculationLink link:definitionLink link:presentationLink 995624 - Disclosure - Note 13 - Stock-Based Compensation - Schedule for Share-based Compensation Expenses (Details) link:calculationLink link:definitionLink link:presentationLink 995625 - Disclosure - Note 14 - Asset Acquisitions (Details Textual) link:calculationLink link:definitionLink link:presentationLink 995626 - Disclosure - Note 15 - Income Taxes (Details Textual) link:calculationLink link:definitionLink link:presentationLink 995627 - Disclosure - Note 15 - Income Taxes - Schedule of Income Tax Provision (Details) link:calculationLink link:definitionLink link:presentationLink 995628 - Disclosure - Note 15 - Income Taxes - Schedule of Effective Income Tax Rate Reconciliation (Details) link:calculationLink link:definitionLink link:presentationLink 995629 - Disclosure - Note 15 - Income Taxes - Schedule of Deferred Tax Assets and Liabilities (Details) link:calculationLink link:definitionLink link:presentationLink 995630 - Disclosure - Note 17 - Related Parties (Details Textual) link:calculationLink link:definitionLink link:presentationLink 995631 - Disclosure - Note 17 - Related Parties - Summary of Related Party Transactions (Details) link:calculationLink link:definitionLink link:presentationLink 995632 - Disclosure - Note 18 - Subsequent Events (Details Textual) link:calculationLink link:definitionLink link:presentationLink