v3.26.1
Note 5 - Stockholders' Equity, Equity Incentive Plans, And Stock-Based Compensation - Stock Option Activity (Details) - USD ($)
 12 Months Ended
Dec. 31, 2025
Dec. 31, 2024
Dec. 31, 2023
Balance, number of options outstanding (in shares) 158,098    
Share-Based Payment Arrangement, Option [Member]      
Balance, number of options outstanding (in shares) 127,971 79,028  
Balance, weighted average exercise price (in dollars per share) $ 81.4 $ 130.2  
Balance, weighted average remaining contractual term (Year) 8 years 2 months 19 days 8 years 10 months 17 days 9 years 1 month 9 days
Balance, aggregate intrinsic value $ 0 $ 683,016 $ 300,969
Granted, number of options outstanding (in shares) 47,627 54,780 [1]  
Granted, weighted average exercise price (in dollars per share) $ 34.6 $ 24.2 [1]  
Expired/Cancelled, Number of Options Outstanding (in shares) (17,500) (5,837)  
Expired/Cancelled, Weighted Average Exercise Price (in dollars per share) $ 67.8 $ 205.4  
Expired/Cancelled (in shares) 17,500 5,837  
Balance, number of options outstanding (in shares) 158,098 127,971 79,028
Balance, weighted average exercise price (in dollars per share) $ 68.8 $ 81.4 $ 130.2
Options vested and exercisable, number of options outstanding (in shares) 121,693    
Options vested and exercisable, weighted average exercise price (in dollars per share) $ 76.8    
Options vested and exercisable, weighted average remaining contractual term (Year) 8 years 18 days    
Options vested and exercisable, aggregate intrinsic value $ 0    
[1] * For the year ended December 31, 2024, the Company settled certain accrued bonus amounts through the issuance of a total of 16,641 stock options to certain employees, in lieu of cash bonuses. The fair value of those stock options was approximately $330,816 and this amount was recorded directly to additional paid-in capital on the consolidated balance sheet as the stock options were issued to settle an accrued bonus amount for which the associated expense was previously recognized in the consolidated statement of operations. This amount is not included within the expenses disclosed below.