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Acquisitions of Assets - Additional Information (Details)		1 Months Ended					3 Months Ended	12 Months Ended
	Jul. 31, 2025 USD ($)	Dec. 31, 2023 USD ($) shares	Oct. 31, 2023 USD ($)	Feb. 28, 2022 USD ($)	Sep. 30, 2021 USD ($) Agreements shares	Jun. 30, 2020 USD ($)	Dec. 31, 2023 USD ($)	Dec. 31, 2025 USD ($) Milestones	Dec. 31, 2024 USD ($)	Dec. 31, 2023 USD ($)
Business Combination [Line Items]
Acquired in-process research and development								$ 5,000,000	$ 0
Amgen Inc.
Business Combination [Line Items]
Number of license agreements \| Agreements					2
Vanderbilt IPR&D Assets
Business Combination [Line Items]
Contingent consideration deemed due or payable								$ 0
BlackThorn Merger Agreement
Business Combination [Line Items]
Contingent consideration, milestone payment settled in cash						$ 10,000,000
Number of milestone achieved \| Milestones								0
BlackThorn Merger Agreement \| BlackThorn Therapeutics, Inc.
Business Combination [Line Items]
Contingent consideration deemed due or payable								$ 0
Contingent consideration payable in cash		$ 2,300,000
Acquired in-process research and developed expense							$ 60,800,000
BlackThorn Merger Agreement \| BlackThorn Therapeutics, Inc. \| Common Stock
Business Combination [Line Items]
Shares issued based on volume weighted average price per share prior to date milestone was met \| shares		6,072,445
BlackThorn Merger Agreement \| navacaprant
Business Combination [Line Items]
Milestone payment due description								milestone payment that became due in October 2023 upon dosing the first patient in the Phase 3 clinical trial for navacaprant,
BlackThorn Merger Agreement \| navacaprant \| Maximum \| Development and Regulatory Approval Milestones
Business Combination [Line Items]
Contingent consideration						365,000,000
BlackThorn Merger Agreement \| navacaprant \| Maximum \| Sales-based Milestones
Business Combination [Line Items]
Contingent consideration						450,000,000
BlackThorn Merger Agreement \| NMRA-511 \| Maximum \| Development and Regulatory Approval Milestones
Business Combination [Line Items]
Contingent consideration						100,000,000
BlackThorn Merger Agreement \| NMRA-511 \| Maximum \| Sales-based Milestones
Business Combination [Line Items]
Contingent consideration						$ 100,000,000
BlackThorn Carveout Plan
Business Combination [Line Items]
Number of milestone achieved \| Milestones								0
Contingent consideration deemed due or payable								$ 0
Asset acquisition compensation recognized and paid										$ 1,800,000
Amgen Inc. Licenses \| Amgen Inc.
Business Combination [Line Items]
Number of milestone achieved \| Milestones								0
Contingent consideration deemed due or payable								$ 0
Amgen Inc. Licenses \| Amgen Inc. \| Series A-2
Business Combination [Line Items]
Upfront consideration transferred shares \| shares					20,000,000
Acquisition date fair value of shares transferred					$ 157,000,000
Amgen Inc. Licenses \| Amgen Inc. \| Maximum \| Case One
Business Combination [Line Items]
Contingent consideration payable in cash					360,000,000
Amgen Inc. Licenses \| Amgen Inc. \| Maximum \| Commercial Milestone Payment \| Case Two
Business Combination [Line Items]
Contingent consideration payable in cash					$ 360,000,000
Vanderbilt License
Business Combination [Line Items]
Contingent consideration, milestone payment settled in cash	$ 5,000,000		$ 2,000,000
Number of milestone achieved \| Milestones								0
Acquired in-process research and development										$ 800,000
Vanderbilt License \| Maximum \| Achievement of Specified Development Events
Business Combination [Line Items]
Contingent consideration payable in cash				$ 42,000,000
Vanderbilt License \| Maximum \| Achievement of Specified Commercialization Events
Business Combination [Line Items]
Contingent consideration payable in cash				380,000,000
Vanderbilt License \| Vanderbilt IPR&D Assets
Business Combination [Line Items]
Upfront cash payment				$ 13,000,000