v3.26.1
CONSOLIDATED STATEMENTS OF CASH FLOWS - USD ($)
$ in Thousands
 12 Months Ended
Dec. 31, 2025
Dec. 31, 2024
Cash flows from operating activities:    
Net loss $ (114,201) $ (147,791)
Adjustments to reconcile net loss to net cash used in operating activities:    
Share-based compensation expense 22,105 25,191
Foreign currency (gain) loss (2,146) 2,886
Depreciation and amortization 12,542 12,828
Change in right-of-use assets 6,581 4,006
Gain on termination of lease liabilities (1,465) (172)
Loss on disposal of equipment, furniture and fixtures 355 9
Loss on equity method investment   17
Amortization of interest on asset retirement obligations 153 209
Amortization of debt discount 1,117 1,103
Acquired in-process research and development 568  
Gain on sale of nonfinancial assets   (28,434)
(Increase) decrease in operating assets:    
Accounts receivable - related party (2,337) 6,325
Contract assets - related party 986 (954)
Inventory 428 (387)
Prepaid expenses 720 (1,328)
Tax incentive receivable (5,916) 4,055
Other current assets (365) (2,302)
Other assets, net (159) 759
Increase (decrease) in operating liabilities:    
Accounts payable (12,313) 10,738
Accrued expenses 4,409 (13,959)
Change in lease liabilities (6,235) (3,990)
Other current liabilities 49,545 32
Deferred revenue - related party (731) 26,664
Net cash used in operating activities (46,359) (104,495)
Cash flows from investing activities:    
Purchase of property, plant and equipment (3,826) (4,955)
Acquisition of in-process research and development assets (410)  
Proceeds from sale of equipment, furniture and fixtures 129  
Proceeds from sale of nonfinancial assets   28,434
Net cash (used in) provided by investing activities (4,107) 23,479
Cash flows from financing activities:    
Exercise of share options 257  
Payments of withholdings on shares withheld for income taxes (2,991) (2,340)
Payments on lease obligations - financing leases (29)  
Proceeds from the issuance of ordinary shares 15,074 59,390
Issuance costs in connection with ordinary shares (39) (2,516)
Net cash provided by financing activities 12,272 54,534
Net decrease in cash, cash equivalents and restricted cash (38,194) (26,482)
Effect of exchange rate changes on cash, cash equivalents and restricted cash 719 1,501
Cash, cash equivalents and restricted cash at beginning of the year 105,668 130,649
Cash, cash equivalents and restricted cash at end of the year 68,193 105,668
Supplemental disclosure of non-cash transactions:    
Fixed asset acquisitions included in accounts payable and accrued expenses 1,280 851
Right-of-Use Asset Obtained in Exchange for Operating Lease Liability 8,556  
Right-of-use assets obtained in exchange for lease liabilities 8,721  
Change in estimate of asset retirement obligation (1,676) 345
Reversal of issuance costs 50  
Supplemental disclosure of cash flow information:    
Cash paid for interest $ 11,036 $ 12,029