v3.26.1
Principal Business Activity (Details) - USD ($)
$ in Thousands
1 Months Ended 3 Months Ended 12 Months Ended
Nov. 07, 2025
Mar. 09, 2025
Dec. 31, 2023
Dec. 31, 2021
Mar. 31, 2019
Mar. 31, 2026
Dec. 31, 2025
Dec. 31, 2024
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                
Accumulated deficit             $ 816,223 $ 702,022
Cash flows from operations             46,359 104,495
Cash, cash equivalents     $ 130,649       68,193 105,668
Janssen Pharmaceuticals Inc | Collaboration Agreement                
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                
Non-refundable upfront cash funding         $ 100,000      
Milestone funding       $ 30,000        
Janssen Pharmaceuticals Inc | Asset Purchase Agreement                
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                
Non-refundable upfront cash funding     65,000          
Milestone funding               $ 60,000
Milestone funding for extension of RPGR product clinical trials     50,000          
Milestone funding for development of drug substances     10,000          
Milestone funding for development of drug products     5,000          
Milestone funding for sale of drug products in the US     175,000          
Milestone funding for sale of drug products in the UK, France, Germany, Spain and Italy     75,000          
Milestone funding for transfer of manufacturing technology     25,000          
Milestone funding upon regulatory approval     10,000          
Hologen Limited | Collaboration Agreement                
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                
Class A shares of Hologen received in transaction   500,000            
Hologen Limited | Hologen Strategic Agreement                
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                
Milestone funding upfront payment received   $ 200,000            
Additional funding payment received             50,000  
Funding receivables             $ 5,000  
Class A share ownership percentage of Hologen Neuro   30.00%            
Class B share ownership percentage of Hologen Neuro   70.00%            
Milestone funding to provide additional capital   $ 230,000            
Percentage approval of directors   70.00%            
Hologen Limited | Manufacturing Framework Agreement                
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                
Percentage approval of directors   70.00%            
Purchase option after twelve months, percentage of Company's outstanding common shares   40.00%            
Vesting period, irrevocable option to purchase shares of MeiraGTx Manufacturing   3 years            
Eli Lilly | Eli Lilly Collaboration Agreement                
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                
Initial funding $ 75,000              
Contingent funding available 400,000              
Milestone funding contingent on development and regulatory approval $ 135,000              
Maximum | Janssen Pharmaceuticals Inc | Asset Purchase Agreement                
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                
Contingent funding available     $ 350,000          
Maximum | Hologen Limited | Hologen Strategic Agreement                
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                
Milestone funding to provide additional capital   $ 230,000            
Subsequent Event | Hologen Limited | Hologen Strategic Agreement                
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                
Additional funding payment received           $ 55,000    
Subsequent Event | Eli Lilly | Eli Lilly Collaboration Agreement                
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                
Additional funding payment received           $ 55,000