Share-Based Compensation (Tables)
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12 Months Ended |
Dec. 31, 2025 |
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| Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items] |
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| Schedule of Share Option Activity |
| | | | | | | | | | | | | | | | | Weighted- | | | | | | Weighted- | | Average | | | | | | Average | | Remaining | | | | Number of | | Exercise | | Contractual | | | | Options | | Price | | Term (years) | Outstanding at December 31, 2024 | | | 8,232,587 | | $ | 12.57 | | 5.35 | Granted | | | 222,050 | | $ | 6.07 | | | Exercised | | | (38,284) | | $ | 6.73 | | | Forfeited | | | (557,015) | | $ | 14.56 | | | Outstanding at December 31, 2025 | | | 7,859,338 | | $ | 12.29 | | 4.58 | Options exercisable at December 31, 2025 | | | 7,116,750 | | $ | 12.78 | | 4.25 | Options vested and expected to vest at December 31, 2025 | | | 7,859,338 | | $ | 12.29 | | 4.58 | Aggregate intrinsic value of options outstanding as of December 31, 2025 | | $ | 4,039 | | | | | | Aggregate intrinsic value of options exercisable as of December 31, 2025 | | $ | 3,370 | | | | | |
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| Schedule of Inputs Used in Determining Fair Value of Share Options |
| | | | | | | 2025 | | 2024 | Risk-free interest rate | | 3.81 - 4.13% | | 4.04 - 4.17% | Expected volatility | | 78% | | 67% | Expected dividend yield | | 0% | | 0% | Expected term (in years) | | 6.01 | | 3.6 - 6.1 |
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| Schedule of Restricted Share Unit (RSU) Activity |
| | | | | | | | | | | | Weighted- | | | Number of | | Average | | | Restricted | | Grant Date | | | Share Units | | Fair Value | Outstanding at December 31, 2024 | | | 4,252,250 | | $ | 8.91 | Granted | | | 3,184,500 | | $ | 6.17 | Vested | | | (1,222,500) | | $ | 11.52 | Forfeited | | | (30,000) | | $ | 6.16 | Outstanding at December 31, 2025 | | | 6,184,250 | | $ | 7.00 |
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| Schedule of Share-Based Compensation Expense |
| | | | | | | | | Years Ended December 31, | | | 2025 | | 2024 | Research and development | | $ | 8,222 | | $ | 11,132 | General and administrative | | | 13,883 | | | 14,059 | Total share-based compensation | | $ | 22,105 | | $ | 25,191 |
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| Employee Stock Option |
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| Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items] |
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| Schedule of Share-Based Compensation Expense |
| | | | | | | | | Years Ended December 31, | | | 2025 | | 2024 | Research and development | | $ | 3,375 | | $ | 6,062 | General and administrative | | | 2,061 | | | 3,892 | Total share-based compensation | | $ | 5,436 | | $ | 9,954 |
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| Restricted Share Units |
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| Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items] |
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| Schedule of Share-Based Compensation Expense |
| | | | | | | | | Years Ended December 31, | | | 2025 | | 2024 | Research and development | | $ | 4,847 | | $ | 5,070 | General and administrative | | | 11,822 | | | 10,167 | Total share-based compensation | | $ | 16,669 | | $ | 15,237 |
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