The following table is a summary of the segment loss, including significant segment expenses for the years ended December 31, 2025 and 2024 (in thousands):


	Year Ended December 31,
	2025		2024
In-process research and development	$	10,000	$	10,000
AXN-2510/IMM2510	20,351		1,291
Other program expenses(1) (2)	4,387		9,901
General and administrative(1)	26,687		41,246
Restructuring charges	16,622		7,493
Depreciation	534		3,610
Interest income	(3,858)		(6,987)
Interest expense	5,829		8,992
Other income, net	(9,180)		(1,411)
Segment net loss	$	71,372	$	74,135

(1) Depreciation expense is removed from both “General and administrative” and “Other program expense” and is disclosed separately.

(2) Other program expenses consist of costs related to the Company’s past development of its CoStAR-TIL technology.