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<!-- Created: Fri Mar 27 17:01:38 UTC 2026 -->
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  <xs:element name="StockIssuedDuringPeriodValueReverseStockSplits" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="credit" nillable="true" substitutionGroup="xbrli:item" id="apm_StockIssuedDuringPeriodValueReverseStockSplits"/>
  <xs:element name="AdjustmentstoAdditionalPiadInCapitaAcquisitionOfNoncontrollingInterest" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="credit" nillable="true" substitutionGroup="xbrli:item" id="apm_AdjustmentstoAdditionalPiadInCapitaAcquisitionOfNoncontrollingInterest"/>
  <xs:element name="StockIssuedDuringPeriodValueIssuanceOfClassAOrdinarySharesUponJanuary2025Offering" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="credit" nillable="true" substitutionGroup="xbrli:item" id="apm_StockIssuedDuringPeriodValueIssuanceOfClassAOrdinarySharesUponJanuary2025Offering"/>
  <xs:element name="StockIssuedDuringPeriodSharesIssuanceOfClassAOrdinarySharesUponJanuary2025Offering" type="xbrli:sharesItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="apm_StockIssuedDuringPeriodSharesIssuanceOfClassAOrdinarySharesUponJanuary2025Offering"/>
  <xs:element name="StockIssuedDuringPeriodValueIssuanceOfClassAOrdinarySharesUponOctober2025Offering" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="credit" nillable="true" substitutionGroup="xbrli:item" id="apm_StockIssuedDuringPeriodValueIssuanceOfClassAOrdinarySharesUponOctober2025Offering"/>
  <xs:element name="StockIssuedDuringPeriodSharesIssuanceOfClassAOrdinarySharesUponOctober2025Offering" type="xbrli:sharesItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="apm_StockIssuedDuringPeriodSharesIssuanceOfClassAOrdinarySharesUponOctober2025Offering"/>
  <xs:element name="LossGainOnInvestmentsInMarketableSecuritiesNet" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="credit" nillable="true" substitutionGroup="xbrli:item" id="apm_LossGainOnInvestmentsInMarketableSecuritiesNet"/>
  <xs:element name="AllowanceForCreditLossOfDueFromARelatedParty" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="debit" nillable="true" substitutionGroup="xbrli:item" id="apm_AllowanceForCreditLossOfDueFromARelatedParty"/>
  <xs:element name="WriteoffOfPrepaymentAndOtherReceivables" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="debit" nillable="true" substitutionGroup="xbrli:item" id="apm_WriteoffOfPrepaymentAndOtherReceivables"/>
  <xs:element name="InterestExpenseAndAccretionOfConvertibleDebts" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="debit" nillable="true" substitutionGroup="xbrli:item" id="apm_InterestExpenseAndAccretionOfConvertibleDebts"/>
  <xs:element name="ReversalOfDeferredCashBonus" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="debit" nillable="true" substitutionGroup="xbrli:item" id="apm_ReversalOfDeferredCashBonus"/>
  <xs:element name="RepaymentOfLoanAndInterestFromARelatedParty" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="credit" nillable="true" substitutionGroup="xbrli:item" id="apm_RepaymentOfLoanAndInterestFromARelatedParty"/>
  <xs:element name="ProceedsFromIssuanceOfClassAOrdinarySharesAndWarrant" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="debit" nillable="true" substitutionGroup="xbrli:item" id="apm_ProceedsFromIssuanceOfClassAOrdinarySharesAndWarrant"/>
  <xs:element name="PaymentsRelatedToOfferingCosts" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="credit" nillable="true" substitutionGroup="xbrli:item" id="apm_PaymentsRelatedToOfferingCosts"/>
  <xs:element name="ReclassificationOfPlacementAgentWarrantRedemptionAmount" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="credit" nillable="true" substitutionGroup="xbrli:item" id="apm_ReclassificationOfPlacementAgentWarrantRedemptionAmount"/>
  <xs:element name="RightofuseAssetsObtainedInExchangeForNewOperatingLeaseLiabilities" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="credit" nillable="true" substitutionGroup="xbrli:item" id="apm_RightofuseAssetsObtainedInExchangeForNewOperatingLeaseLiabilities"/>
  <xs:element name="SettlementOfDeferredCashBonusByIssuanceOfShareOptionsOrShares" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="credit" nillable="true" substitutionGroup="xbrli:item" id="apm_SettlementOfDeferredCashBonusByIssuanceOfShareOptionsOrShares"/>
  <xs:element name="NoncontrollingInterestsPolicyTextBlock" type="dtr:textBlockItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="apm_NoncontrollingInterestsPolicyTextBlock"/>
  <xs:element name="OperatingLeasesPolicyTextBlock" type="dtr:textBlockItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="apm_OperatingLeasesPolicyTextBlock"/>
  <xs:element name="WarrantLiabilitiesPolicyTextBlock" type="dtr:textBlockItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="apm_WarrantLiabilitiesPolicyTextBlock"/>
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  <xs:element name="RecentlyIssuedAccountingStandardsWhichHaveNotYetBeenAdoptedPolicyTextBlock" type="dtr:textBlockItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="apm_RecentlyIssuedAccountingStandardsWhichHaveNotYetBeenAdoptedPolicyTextBlock"/>
  <xs:element name="PropertyPlantAndEquipmentUsefullLifeTableTextBlock" type="dtr:textBlockItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="apm_PropertyPlantAndEquipmentUsefullLifeTableTextBlock"/>
  <xs:element name="SummaryofSignificantAccountingPoliciesTablesTable" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrldt:hypercubeItem" id="apm_SummaryofSignificantAccountingPoliciesTablesTable"/>
  <xs:element name="SummaryofSignificantAccountingPoliciesTablesLineItems" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="apm_SummaryofSignificantAccountingPoliciesTablesLineItems"/>
  <xs:element name="ScheduleOfLongTermDepositsTableTextBlock" type="dtr:textBlockItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="apm_ScheduleOfLongTermDepositsTableTextBlock"/>
  <xs:element name="ScheduleOfIncomeTaxesPaidTableTextBlock" type="dtr:textBlockItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="apm_ScheduleOfIncomeTaxesPaidTableTextBlock"/>
  <xs:element name="IncomeTaxesTablesTable" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrldt:hypercubeItem" id="apm_IncomeTaxesTablesTable"/>
  <xs:element name="ScheduleOfMilestonePaymentsAreToBeMadeUponAchievementsOfCertainConditionsTableTextBlock" type="dtr:textBlockItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="apm_ScheduleOfMilestonePaymentsAreToBeMadeUponAchievementsOfCertainConditionsTableTextBlock"/>
  <xs:element name="SummaryofSignificantAccountingPoliciesScheduleofFairValueHierarchyoftheGroupsFinancialAssetsandLiabilitiesMeasuredatFairValueonaRecurringBasisDetailsTable" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrldt:hypercubeItem" id="apm_SummaryofSignificantAccountingPoliciesScheduleofFairValueHierarchyoftheGroupsFinancialAssetsandLiabilitiesMeasuredatFairValueonaRecurringBasisDetailsTable"/>
  <xs:element name="LongTermInvestmentScheduleofCarryingValueoftheNonMarketableInvestmentsHeldDetailsTable" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrldt:hypercubeItem" id="apm_LongTermInvestmentScheduleofCarryingValueoftheNonMarketableInvestmentsHeldDetailsTable"/>
  <xs:element name="UpwardAdjustments" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="instant" xbrli:balance="debit" nillable="true" substitutionGroup="xbrli:item" id="apm_UpwardAdjustments"/>
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  <xs:element name="PrepaidServiceFee" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="instant" xbrli:balance="debit" nillable="true" substitutionGroup="xbrli:item" id="apm_PrepaidServiceFee"/>
  <xs:element name="OtherDepositsCurrent" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="instant" xbrli:balance="debit" nillable="true" substitutionGroup="xbrli:item" id="apm_OtherDepositsCurrent"/>
  <xs:element name="RentalDeposits" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="instant" xbrli:balance="debit" nillable="true" substitutionGroup="xbrli:item" id="apm_RentalDeposits"/>
  <xs:element name="ResearchAndDevelopmentExpensesPayable" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="instant" xbrli:balance="credit" nillable="true" substitutionGroup="xbrli:item" id="apm_ResearchAndDevelopmentExpensesPayable"/>
  <xs:element name="IncomeTaxesScheduleofIncomeLossBeforeIncomeTaxExpenseDetailsTable" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrldt:hypercubeItem" id="apm_IncomeTaxesScheduleofIncomeLossBeforeIncomeTaxExpenseDetailsTable"/>
  <xs:element name="EffectiveIncomeTaxRateNetLossBeforeTax" type="dtr:percentItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="apm_EffectiveIncomeTaxRateNetLossBeforeTax"/>
  <xs:element name="IncomeTaxesScheduleofIncomeTaxesPaidDetailsTable" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrldt:hypercubeItem" id="apm_IncomeTaxesScheduleofIncomeTaxesPaidDetailsTable"/>
  <xs:element name="DeferredTaxAssetsDepreciationAndAmortization" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="instant" xbrli:balance="debit" nillable="true" substitutionGroup="xbrli:item" id="apm_DeferredTaxAssetsDepreciationAndAmortization"/>
  <xs:element name="ValuationAllowanceDeferredTaxAssetIncrease" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="credit" nillable="true" substitutionGroup="xbrli:item" id="apm_ValuationAllowanceDeferredTaxAssetIncrease"/>
  <xs:element name="ValuationAllowanceDeferredTaxAssetDecreaseAmount" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="debit" nillable="true" substitutionGroup="xbrli:item" id="apm_ValuationAllowanceDeferredTaxAssetDecreaseAmount"/>
  <xs:element name="SettlementOfLoanFromARelatedPartyThroughIssuanceOfConvertibleNote" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="debit" nillable="true" substitutionGroup="xbrli:item" id="apm_SettlementOfLoanFromARelatedPartyThroughIssuanceOfConvertibleNote"/>
  <xs:element name="ConsultantSecondmentManagementAndAdministrativeServicesFees" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="debit" nillable="true" substitutionGroup="xbrli:item" id="apm_ConsultantSecondmentManagementAndAdministrativeServicesFees"/>
  <xs:element name="ShareBasedCompensationScheduleoftheOptionActivityDetailsTable" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrldt:hypercubeItem" id="apm_ShareBasedCompensationScheduleoftheOptionActivityDetailsTable"/>
  <xs:element name="SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsExercisableWeightedAverageRemainingContractualTerm" type="xbrli:durationItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="apm_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsExercisableWeightedAverageRemainingContractualTerm"/>
  <xs:element name="CommitmentsandContingenciesScheduleofMilestonePaymentsthattheGroupisRequiredtoPayuptoDifferentAchievementsDetailsTable" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrldt:hypercubeItem" id="apm_CommitmentsandContingenciesScheduleofMilestonePaymentsthattheGroupisRequiredtoPayuptoDifferentAchievementsDetailsTable"/>
  <xs:element name="ContingentMilestonePaymentsSubtotal" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="instant" xbrli:balance="debit" nillable="true" substitutionGroup="xbrli:item" id="apm_ContingentMilestonePaymentsSubtotal"/>
  <xs:element name="SummaryofSignificantAccountingPoliciesScheduleofEstimatedUsefulLivesDetailsTable" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrldt:hypercubeItem" id="apm_SummaryofSignificantAccountingPoliciesScheduleofEstimatedUsefulLivesDetailsTable"/>
  <xs:element name="OrganizationDetailsTable" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrldt:hypercubeItem" id="apm_OrganizationDetailsTable"/>
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  <xs:element name="PercentageOfOutstandingCommonStock" type="dtr:percentItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="apm_PercentageOfOutstandingCommonStock"/>
  <xs:element name="workingCapital" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="instant" xbrli:balance="credit" nillable="true" substitutionGroup="xbrli:item" id="apm_workingCapital"/>
  <xs:element name="SummaryofSignificantAccountingPoliciesDetailsTable" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrldt:hypercubeItem" id="apm_SummaryofSignificantAccountingPoliciesDetailsTable"/>
  <xs:element name="LongTermInvestmentDetailsTable" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrldt:hypercubeItem" id="apm_LongTermInvestmentDetailsTable"/>
  <xs:element name="EquitySecuritiesWithoutReadilyDeterminableFairValueUpwardPriceUpwardAdjustments" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="instant" xbrli:balance="debit" nillable="true" substitutionGroup="xbrli:item" id="apm_EquitySecuritiesWithoutReadilyDeterminableFairValueUpwardPriceUpwardAdjustments"/>
  <xs:element name="NoncontrollingInterestOwnershipPercentageByNoncontrollingOwners" type="dtr:percentItemType" abstract="false" xbrli:periodType="instant" nillable="true" substitutionGroup="xbrli:item" id="apm_NoncontrollingInterestOwnershipPercentageByNoncontrollingOwners"/>
  <xs:element name="PropertyandEquipmentNetDetailsTable" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrldt:hypercubeItem" id="apm_PropertyandEquipmentNetDetailsTable"/>
  <xs:element name="IntangibleAssetsNetDetailsTable" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrldt:hypercubeItem" id="apm_IntangibleAssetsNetDetailsTable"/>
  <xs:element name="IncomeTaxesDetailsTable" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrldt:hypercubeItem" id="apm_IncomeTaxesDetailsTable"/>
  <xs:element name="AssessableTaxProfitsRate" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="credit" nillable="true" substitutionGroup="xbrli:item" id="apm_AssessableTaxProfitsRate"/>
  <xs:element name="RemainingAssessableProfitsPercentage" type="dtr:percentItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="apm_RemainingAssessableProfitsPercentage"/>
  <xs:element name="SubsidiariesIncomeTaxRate" type="dtr:percentItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="apm_SubsidiariesIncomeTaxRate"/>
  <xs:element name="LossCarryforwardCancelled" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="instant" xbrli:balance="credit" nillable="true" substitutionGroup="xbrli:item" id="apm_LossCarryforwardCancelled"/>
  <xs:element name="RelatedPartyBalancesandTransactionsDetailsTable" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrldt:hypercubeItem" id="apm_RelatedPartyBalancesandTransactionsDetailsTable"/>
  <xs:element name="DecreasedOwnershipPercentage" type="dtr:percentItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="apm_DecreasedOwnershipPercentage"/>
  <xs:element name="LoansInterestbearingRate" type="dtr:percentItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="apm_LoansInterestbearingRate"/>
  <xs:element name="ServicesFees" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="debit" nillable="true" substitutionGroup="xbrli:item" id="apm_ServicesFees"/>
  <xs:element name="ServicesFeesAdjusted" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="credit" nillable="true" substitutionGroup="xbrli:item" id="apm_ServicesFeesAdjusted"/>
  <xs:element name="VariableInterestEntityDetailsTable" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrldt:hypercubeItem" id="apm_VariableInterestEntityDetailsTable"/>
  <xs:element name="ShareOfEconomicBenefit" type="xbrli:sharesItemType" abstract="false" xbrli:periodType="instant" nillable="true" substitutionGroup="xbrli:item" id="apm_ShareOfEconomicBenefit"/>
  <xs:element name="ShareOfEconomic" type="dtr:perShareItemType" abstract="false" xbrli:periodType="instant" nillable="true" substitutionGroup="xbrli:item" id="apm_ShareOfEconomic"/>
  <xs:element name="LeaseDetailsTable" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrldt:hypercubeItem" id="apm_LeaseDetailsTable"/>
  <xs:element name="ConvertibleNoteDetailsTable" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrldt:hypercubeItem" id="apm_ConvertibleNoteDetailsTable"/>
  <xs:element name="OrdinarySharesDetailsTable" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrldt:hypercubeItem" id="apm_OrdinarySharesDetailsTable"/>
  <xs:element name="StockIssuedDuringPeriodSharesConversionOfUnit" type="xbrli:sharesItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="apm_StockIssuedDuringPeriodSharesConversionOfUnit"/>
  <xs:element name="AllocatedToTheLiabilityClassifiedInvestorWarrants" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="credit" nillable="true" substitutionGroup="xbrli:item" id="apm_AllocatedToTheLiabilityClassifiedInvestorWarrants"/>
  <xs:element name="AllocatedToTheEquityClassified" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="credit" nillable="true" substitutionGroup="xbrli:item" id="apm_AllocatedToTheEquityClassified"/>
  <xs:element name="GrantdateFairValue" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="credit" nillable="true" substitutionGroup="xbrli:item" id="apm_GrantdateFairValue"/>
  <xs:element name="ShareBasedCompensationDetailsTable" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrldt:hypercubeItem" id="apm_ShareBasedCompensationDetailsTable"/>
  <xs:element name="NonControllingInterestDetailsTable" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrldt:hypercubeItem" id="apm_NonControllingInterestDetailsTable"/>
  <xs:element name="WarrantsDetailsTable" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrldt:hypercubeItem" id="apm_WarrantsDetailsTable"/>
  <xs:element name="AmountOfWarrantRedemption" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="debit" nillable="true" substitutionGroup="xbrli:item" id="apm_AmountOfWarrantRedemption"/>
  <xs:element name="ACCMedicalLimitedMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="apm_ACCMedicalLimitedMember"/>
  <xs:element name="APTUSMANAGEMENTLIMITEDMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="apm_APTUSMANAGEMENTLIMITEDMember"/>
  <xs:element name="ActiculeLifeSciencesLimitedMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="apm_ActiculeLifeSciencesLimitedMember"/>
  <xs:element name="AencoTechnologiesLtdMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="apm_AencoTechnologiesLtdMember"/>
  <xs:element name="AeneasGroupLimitedMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="apm_AeneasGroupLimitedMember"/>
  <xs:element name="AeneasManagementLimitedMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="apm_AeneasManagementLimitedMember"/>
  <xs:element name="AlzheonMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="apm_AlzheonMember"/>
  <xs:element name="AptorumMedicalLimitedMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="apm_AptorumMedicalLimitedMember"/>
  <xs:element name="AptorumTherapeuticsLimitedMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="apm_AptorumTherapeuticsLimitedMember"/>
  <xs:element name="CGYInvestmentsLimitedMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="apm_CGYInvestmentsLimitedMember"/>
  <xs:element name="ChairmanAndCEOMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="apm_ChairmanAndCEOMember"/>
  <xs:element name="ComputerSoftwareMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="apm_ComputerSoftwareMember"/>
  <xs:element name="ConvertibleNotesMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="apm_ConvertibleNotesMember"/>
  <xs:element name="EmployeesAndExternalConsultantsMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="apm_EmployeesAndExternalConsultantsMember"/>
  <xs:element name="EmployeesMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="apm_EmployeesMember"/>
  <xs:element name="FirstCommercialSaleMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="apm_FirstCommercialSaleMember"/>
  <xs:element name="FromEnteringPhase1ToBeforeFirstCommercialSaleMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="apm_FromEnteringPhase1ToBeforeFirstCommercialSaleMember"/>
  <xs:element name="GovernmentSubsidiesMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="apm_GovernmentSubsidiesMember"/>
  <xs:element name="GroupsSubsidiariesMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="apm_GroupsSubsidiariesMember"/>
  <xs:element name="IanHuenMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="apm_IanHuenMember"/>
  <xs:element name="InvesteeBMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="apm_InvesteeBMember"/>
  <xs:element name="InvestmentAMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="apm_InvestmentAMember"/>
  <xs:element name="InvestmentBMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="apm_InvestmentBMember"/>
  <xs:element name="InvestmentCMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="apm_InvestmentCMember"/>
  <xs:element name="InvestorWarrantMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="apm_InvestorWarrantMember"/>
  <xs:element name="JuneTwoThousandTwentyThreeNotesMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="apm_JuneTwoThousandTwentyThreeNotesMember"/>
  <xs:element name="JurchenInvestmentCorporationMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="apm_JurchenInvestmentCorporationMember"/>
  <xs:element name="LaboratoryEquipmentMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="apm_LaboratoryEquipmentMember"/>
  <xs:element name="LibraMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="apm_LibraMember"/>
  <xs:element name="LibraSciencesLimitedMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="apm_LibraSciencesLimitedMember"/>
  <xs:element name="MeasurementInputDilutionFactorMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="apm_MeasurementInputDilutionFactorMember"/>
  <xs:element name="MeasurementInputFairValuePerShareMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="apm_MeasurementInputFairValuePerShareMember"/>
  <xs:element name="MiosMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="apm_MiosMember"/>
  <xs:element name="MiosPharmaceuticalsLimitedMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="apm_MiosPharmaceuticalsLimitedMember"/>
  <xs:element name="NetSalesAmountMoreThanCertainThresholdInAYearMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="apm_NetSalesAmountMoreThanCertainThresholdInAYearMember"/>
  <xs:element name="OctoberTwoThousandTwentyFiveOfferingMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="apm_OctoberTwoThousandTwentyFiveOfferingMember"/>
  <xs:element name="OfficeAdministrativeMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="apm_OfficeAdministrativeMember"/>
  <xs:element name="OtherJurisdictionsMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="apm_OtherJurisdictionsMember"/>
  <xs:element name="PathsDiagnosticsPteLimitedMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="apm_PathsDiagnosticsPteLimitedMember"/>
  <xs:element name="PathsInnovationsLimitedMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="apm_PathsInnovationsLimitedMember"/>
  <xs:element name="PlacementAgentWarrantMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="apm_PlacementAgentWarrantMember"/>
  <xs:element name="PlacementAgentWarrantsMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="apm_PlacementAgentWarrantsMember"/>
  <xs:element name="PrepaidPatentedLicensesMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="apm_PrepaidPatentedLicensesMember"/>
  <xs:element name="RelatedPartiesMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="apm_RelatedPartiesMember"/>
  <xs:element name="ScipioLifeSciencesLimitedMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="apm_ScipioLifeSciencesLimitedMember"/>
  <xs:element name="ScipioMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="apm_ScipioMember"/>
  <xs:element name="SepTwoThousandTwentyThreeNotesMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="apm_SepTwoThousandTwentyThreeNotesMember"/>
  <xs:element name="SeriesDConvertiblePreferredStockMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="apm_SeriesDConvertiblePreferredStockMember"/>
  <xs:element name="SeriesEConvertiblePreferredStockMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="apm_SeriesEConvertiblePreferredStockMember"/>
  <xs:element name="ShareOptionPlanMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="apm_ShareOptionPlanMember"/>
  <xs:element name="TalemMedicalGroupLimitedMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="apm_TalemMedicalGroupLimitedMember"/>
  <xs:element name="TwoThousandSeventeenShareOptionPlanMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="apm_TwoThousandSeventeenShareOptionPlanMember"/>
  <xs:element name="GoingConcernAbstract" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="apm_GoingConcernAbstract"/>
  <xs:element name="ScheduleOfCarryingValueOfTheNonMarketableInvestmentsHeldLineItems" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="apm_ScheduleOfCarryingValueOfTheNonMarketableInvestmentsHeldLineItems"/>
  <xs:element name="ScheduleOfIncomeLossBeforeIncomeTaxExpenseLineItems" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="apm_ScheduleOfIncomeLossBeforeIncomeTaxExpenseLineItems"/>
  <xs:element name="ScheduleOfIncomeTaxesPaidLineItems" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="apm_ScheduleOfIncomeTaxesPaidLineItems"/>
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</xs:schema>
