v3.26.1
Consolidated Statements of Operations and Comprehensive Loss - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2025
Dec. 31, 2024
Total revenue, net $ 75,388 $ 10,120
Cost and operating expenses:    
Cost of sales (96,369) (11,387)
Research and development expenses, net (117,689) (138,436)
Selling, general and administrative expenses (131,874) (101,723)
Loss from operations (270,544) (241,426)
Other income (expense):    
Other income, net 515 220
Foreign exchange gains (losses), net 2,163 (989)
Interest income 18,980 32,355
Interest expense, net (36,670) (9,294)
Total other income (expenses), net (15,012) 22,292
Net loss before income tax (285,556) (219,134)
Income tax expense (1,972) (1,528)
Net loss (287,528) (220,662)
Other comprehensive income (loss), net of tax:    
Foreign currency exchange translation adjustment 23,343 135
Unrealized holding gains (losses) on available-for-sale debt securities, net of tax of $0 and $0 475 (317)
Total other comprehensive income (loss), net of tax 23,818 (182)
Total comprehensive loss $ (263,710) $ (220,844)
Basic net loss per ordinary share (in usd per share) $ (1.08) $ (0.86)
Diluted net loss per ordinary share (in usd per share) $ (1.08) $ (0.86)
Weighted-average basic ordinary shares (in shares) 266,138,224 255,161,038
Weighted-average diluted ordinary shares (in shares) 266,138,224 255,161,038
Product revenue, net    
Total revenue, net $ 74,318 $ 0
License revenue    
Total revenue, net $ 1,070 $ 10,120