Insider Trading Arrangements

(a)On February 3, 2026, Vimal Mehta, Chief Executive Officer, adopted a Rule 10b5-1 trading arrangement that is intended to satisfy the affirmative defense of Rule 10b5-1(c) for the sale of up to 199,032 shares of the Company’s common stock to cover taxes due in connection with the vesting of restricted stock units until December 31, 2027.

(b)On February 3, 2026, Richard Steinhart, Chief Financial Officer, adopted a Rule 10b5-1 trading arrangement that is intended to satisfy the affirmative defense of Rule 10b5-1(c) for the sale of up to 70,000 shares of the Company’s common stock to cover taxes due in connection with the vesting of restricted stock units until December 31, 2027.

(c)On February 3, 2026, Javier Rodriguez, Senior Vice President, Chief Legal Officer, adopted a Rule 10b5-1 trading arrangement that is intended to satisfy the affirmative defense of Rule 10b5-1(c) for the sale of up to 70,000 shares of the Company’s common stock to cover taxes due in connection with the vesting of restricted stock units until December 31, 2027.

(d)On February 3, 2026, Frank Yocca, Chief Scientific Officer, adopted a Rule 10b5-1 trading arrangement that is intended to satisfy the affirmative defense of Rule 10b5-1(c) for the sale of up to 70,000 shares of the Company’s common stock to cover taxes due in connection with the vesting of restricted stock units until December 31, 2027.