Exhibit 15.1

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The Directors Biodexa Pharmaceuticals plc 1 Caspian Point Caspian Way Cardiff Wales CF10 4DQ |
DDI: +44 (0)20 7516 2200
Email: dthompson@pkf-l.com
Date: 26 March 2026 |
Consent of Independent Registered Public Accounting Firm – Exhibit 15.1
Dear Sir / Madam
We consent to the inclusion of our audit report dated March 26, 2026 in the Annual Report on Form 20-F on the consolidated financial position of Biodexa Pharmaceuticals plc (the “Group”) and its subsidiaries as of December 31, 2025 and 2024 and the related consolidated statement of comprehensive income, cash flow and changes in equity for the year ended December 31, 2025 and 2024, and the related notes.
Yours faithfully
/s/PKF Littlejohn LLP
PKF Littlejohn LLP
London, United Kingdom
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PKF Littlejohn LLP, Chartered Accountants. A list of members’ names is available at the address below. PKF Littlejohn LLP is a limited liability partnership registered in England and Wales No. OC342572. Registered office at 15 Westferry Circus, London E14 4HD. PKF Littlejohn LLP is a member of PKF Global, the network of member firms of PKF International Limited, each of which is a separate and independent legal entity and does not accept any responsibility or liability for the actions or inactions of any individual member or correspondent firm(s). |
PKF Littlejohn LLP 15 Westferry Circus Canary Wharf, London E14 4HD
T: +44 (0)20 7516 2200 pkf-l.com |