v3.26.1
Consolidated Statements of Cash Flows - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2025
Dec. 31, 2024
Dec. 31, 2023
Cash flows from operating activities:      
Net loss $ (56,033) $ (83,736) $ (101,870)
Adjustments to reconcile net loss to net cash used in operating activities:      
Depreciation and amortization 897 1,040 1,066
Stock-based compensation 8,963 13,011 18,137
Amortization of premiums and discounts on marketable securities (2,002) (5,043) (6,830)
Amortization of debt discount and issuance costs and other non-cash interest 176 259 235
Loss on debt extinguishment 146 0 0
Impairment loss of property and equipment 907 0 208
Impairment loss of right-of-use asset 0 1,549 2,700
Reclassification of currency translation loss 282 0 0
Loss on disposal of property and equipment 290 8 3
Changes in operating assets and liabilities      
Prepaid expenses and other current assets 1,909 335 3,583
Other assets 2,415 3,180 (4,921)
Accounts payable and accrued liabilities (7,338) (3,146) 6,347
Operating lease asset and liabilities (2,389) (1,669) (303)
Net cash used in operating activities (51,777) (74,212) (81,645)
Cash flows from investing activities:      
Purchases of property and equipment (8) (29) (1,810)
Purchases of marketable securities (42,631) (91,337) (180,399)
Maturities of marketable securities 134,981 171,794 258,250
Proceeds from sale of equipment 121 0 5
Net cash provided by investing activities 92,463 80,428 76,046
Cash flows from financing activities:      
Repayment of loan principal and final fee (10,650) 0 0
Proceeds from issuance of common stock under employee stock incentive plans 65 103 638
Net cash (used in) provided by financing activities (10,585) 103 638
Effect of exchange rate changes on cash and cash equivalents 28 (63) (2)
Net increase (decrease) in cash and cash equivalents 30,129 6,256 (4,963)
Cash and cash equivalents at the beginning of period 41,749 35,493 40,456
Cash and cash equivalents at the end of period 71,878 41,749 35,493
Supplemental disclosures of noncash investing and financing information:      
Par value of common stock upon cashless exercise of prefunded warrants 0 0 4
Supplemental disclosures      
Cash paid for interest $ 766 $ 1,335 $ 1,315