Subsequent Event	12 Months Ended
Dec. 31, 2025
Subsequent Events [Abstract]
Subsequent Event	Subsequent Event Enodia Asset Purchase Agreement On March 6, 2026, the Company entered into an asset purchase agreement (the “Asset Purchase Agreement”) with Enodia Therapeutics SAS (“Enodia”), under which Enodia has acquired the Company’s assets from its Sec61-based discovery and development program. Under the terms of the Asset Purchase Agreement, the Company received initial upfront payments totaling $1.0 million, and may receive future payments from Enodia upon achievement of certain development, regulatory and commercial milestones, for a potential total of up to $127 million. In addition, Enodia will pay the Company tiered royalties on any net sales, subject to certain reductions for patent expiration, generic competition and payments for licenses to third party patents.

Subsequent Event

12 Months Ended

Dec. 31, 2025

Enodia Asset Purchase Agreement

On March 6, 2026, the Company entered into an asset purchase agreement (the “Asset Purchase Agreement”) with Enodia Therapeutics SAS (“Enodia”), under which Enodia has acquired the Company’s assets from its Sec61-based discovery and development program. Under the terms of the Asset Purchase Agreement, the Company received initial upfront payments totaling $1.0 million, and may receive future payments from Enodia upon achievement of certain development, regulatory and commercial milestones, for a potential total of up to $127 million. In addition, Enodia will pay the Company tiered royalties on any net sales, subject to certain reductions for patent expiration, generic competition and payments for licenses to third party patents.