v3.26.1
Basis of Presentation and Summary of Significant Accounting Policies - Additional Information (Details)
$ in Millions
 1 Months Ended 12 Months Ended
Dec. 02, 2025
USD ($)
Oct. 21, 2024
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Jul. 01, 2024
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Apr. 29, 2024
USD ($)
Dec. 31, 2023
USD ($)
Apr. 29, 2024
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Dec. 31, 2023
USD ($)
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Jul. 31, 2023
USD ($)
Jul. 31, 2022
USD ($)
Jan. 31, 2020
USD ($)
Dec. 31, 2025
USD ($)
segment
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Dec. 31, 2025
AUD ($)
segment
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Dec. 31, 2024
USD ($)
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Dec. 31, 2023
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Dec. 31, 2022
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Dec. 31, 2020
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Dec. 21, 2023
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Significant Accounting Policies [Line Items]                                  
Cash and cash equivalents                     $ 24,711,356   $ 15,698,174        
Working capital                     3,400,000            
Deferred grant funding                     19,651,452   16,561,625        
Accumulated deficit                     188,688,904   175,289,630        
Net loss                     13,399,274   4,053,599        
Cash flow from operations                     $ 9,900,000            
Number of reportable segments | segment                     1 1          
Number of operating segments | segment                     1 1          
Stock split, conversion ratio     0.0833                            
Basis prior to conversion (in shares) | shares     12                            
Basis after conversion (in shares) | shares     1                            
Restricted cash included in other non-current assets                     $ 300,000   300,000        
Property and equipment, useful life                     5 years            
Deferred offering costs                     $ 900,000   700,000        
Loss on disposal of property and equipment                     0   600,000        
Grant funding recognized during period                     16,400,000   8,800,000        
Other income (expense)                     (153,060)   981,490        
Total revenue                     $ 1,030,193   9,784        
Common stock reserved for issuance (in shares) | shares                     3,217,657            
Income tax provision                     $ 0   0        
Unrecognized tax benefits, net                     3,100,000   2,900,000        
Accrued indemnification provisions                     $ 0   $ 0        
Stock Options | Amended and Restated 2014 Stock Incentive Plan                                  
Significant Accounting Policies [Line Items]                                  
Stock options outstanding (in shares) | shares                     1,409,042   883,334        
Common stock reserved for issuance (in shares) | shares                     540,043            
Warrant                                  
Significant Accounting Policies [Line Items]                                  
Common stock reserved for issuance (in shares) | shares                     1,268,572   1,268,572        
License And Collaboration Revenues                                  
Significant Accounting Policies [Line Items]                                  
Total revenue                     $ 12,000,000.0            
Revenue from contract with customer termination of contract               $ 1,000,000.0                  
Royalty Revenue                                  
Significant Accounting Policies [Line Items]                                  
Total revenue                               $ 26,000  
Purchase And Registration Rights Agreement                                  
Significant Accounting Policies [Line Items]                                  
Sale of stock, number of shares issued in transaction (in shares) | shares                     1,470,000 1,470,000          
Sale Of Future Royalties | Warrant                                  
Significant Accounting Policies [Line Items]                                  
Sale of stock, number of shares issued in transaction (in shares) | shares             5,000,000.0                    
Sale Of Future Royalties | Warrant | Estimate of Fair Value Measurement                                  
Significant Accounting Policies [Line Items]                                  
Warrants and rights outstanding (in shares)         $ 800,000   $ 800,000             $ 800,000      
Lincoln Park Capital Fund, LLC | Purchase And Registration Rights Agreement                                  
Significant Accounting Policies [Line Items]                                  
Authorized amount (up to)   $ 30,000                              
Sale of stock, number of shares issued in transaction (in shares) | shares   137,614                              
Lincoln Park Capital Fund, LLC | Common stock | Purchase And Registration Rights Agreement                                  
Significant Accounting Policies [Line Items]                                  
Authorized amount (up to)   $ 15,000,000.0                              
XOMA | Royalty Purchase Agreement                                  
Significant Accounting Policies [Line Items]                                  
Amount awarded for grant       $ 20,000,000.0                          
Revenue tier threshold, upper range limit       22,000,000.0   $ 22,000,000.0             $ 22,000,000.0        
Maximum royalty payments       88,000,000.0   88,000,000.0                      
Contingent purchase price payments       11,000,000.0   11,000,000.0                      
Issuance costs       $ 1,600,000                          
Other income (expense)                         1,600,000        
Proceeds from royalties received           $ 22,000,000.0                      
United                                  
Significant Accounting Policies [Line Items]                                  
Proceeds from royalties received         5,000,000.0   5,000,000.0                    
Liability related to the sale of future royalties         $ 5,000,000.0   $ 5,000,000.0             $ 5,000,000.0      
Internal rate of return         12.00%   12.00%       12.00%     12.00%      
United | Warrant | Estimate of Fair Value Measurement                                  
Significant Accounting Policies [Line Items]                                  
Warrants and rights outstanding (in shares)                                 $ 800,000
Organon                                  
Significant Accounting Policies [Line Items]                                  
Upfront license fee paid                 $ 10,000,000.0   $ 12,800,000       $ 10,000,000.0    
Reimburse amount, PDUFA fees and other manufacturing expenses               $ 1,000,000.0           $ 1,000,000.0      
Bayer | Collaborative Arrangement                                  
Significant Accounting Policies [Line Items]                                  
Upfront license fee paid $ 1,000,000.0                       $ 1,000,000.0     1,000,000.0  
Bayer | Collaborative Arrangement | Royalty Revenue                                  
Significant Accounting Policies [Line Items]                                  
Total revenue                               $ 20,000,000.0  
Upfront license fee paid                   $ 1,000,000.0              
Minimum                                  
Significant Accounting Policies [Line Items]                                  
Indirect cost allowance percentage                     5.00%            
Cash balance of financial institutions insured by federal deposits insurance corporation                     $ 250,000            
Minimum | Australian Taxation Office                                  
Significant Accounting Policies [Line Items]                                  
Total revenue                       $ 20.0          
Minimum | Lincoln Park Capital Fund, LLC | Purchase And Registration Rights Agreement                                  
Significant Accounting Policies [Line Items]                                  
Authorized amount (up to)   35,000                              
Maximum                                  
Significant Accounting Policies [Line Items]                                  
Indirect cost allowance percentage                     22.00%            
Operating lease, term of contract (in years)                     12 months            
Maximum | Lincoln Park Capital Fund, LLC | Purchase And Registration Rights Agreement                                  
Significant Accounting Policies [Line Items]                                  
Authorized amount (up to)   40,000                              
Maximum | Lincoln Park Capital Fund, LLC | Common stock | Purchase And Registration Rights Agreement                                  
Significant Accounting Policies [Line Items]                                  
Authorized amount (up to)   $ 15,000,000.0